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Items: 21


Diversification of DNA binding specificities enabled SREBP transcription regulators to expand the repertoire of cellular functions that they govern in fungi.

Del Olmo Toledo V, Puccinelli R, Fordyce PM, Pérez JC.

PLoS Genet. 2018 Dec 31;14(12):e1007884. doi: 10.1371/journal.pgen.1007884. eCollection 2018 Dec.


BET-seq: Binding energy topographies revealed by microfluidics and high-throughput sequencing.

Aditham AK, Shimko TC, Fordyce PM.

Methods Cell Biol. 2018;148:229-250. doi: 10.1016/bs.mcb.2018.09.011. Epub 2018 Oct 23.


An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices.

Brower K, Puccinelli R, Markin CJ, Shimko TC, Longwell SA, Cruz B, Gomez-Sjoberg R, Fordyce PM.

HardwareX. 2018 Apr;3:117-134. doi: 10.1016/j.ohx.2017.10.001. Epub 2017 Oct 31.


Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding.

Le DD, Shimko TC, Aditham AK, Keys AM, Longwell SA, Orenstein Y, Fordyce PM.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3702-E3711. doi: 10.1073/pnas.1715888115. Epub 2018 Mar 27.


Programmable Microfluidic Synthesis of Over One Thousand Uniquely Identifiable Spectral Codes.

Nguyen HQ, Baxter BC, Brower K, Diaz-Botia CA, DeRisi JL, Fordyce PM, Thorn KS.

Adv Opt Mater. 2017 Feb 2;5(3). pii: 1600548. doi: 10.1002/adom.201600548. Epub 2016 Oct 18.


Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices.

Brower K, White AK, Fordyce PM.

J Vis Exp. 2017 Jan 27;(119). doi: 10.3791/55276.


Correction: Programmable microfluidic synthesis of spectrally encoded microspheres.

Gerver RE, Gómez-Sjöberg R, Baxter BC, Thorn KS, Fordyce PM, Diaz-Botia CA, Helms BA, DeRisi JL.

Lab Chip. 2015 Feb 21;15(4):1213. doi: 10.1039/c5lc90018b.


How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes.

Pérez JC, Fordyce PM, Lohse MB, Hanson-Smith V, DeRisi JL, Johnson AD.

Genes Dev. 2014 Jun 15;28(12):1272-7. doi: 10.1101/gad.242271.114. Epub 2014 May 29.


Structure of the transcriptional network controlling white-opaque switching in Candida albicans.

Hernday AD, Lohse MB, Fordyce PM, Nobile CJ, DeRisi JL, Johnson AD.

Mol Microbiol. 2013 Oct;90(1):22-35. doi: 10.1111/mmi.12329. Epub 2013 Aug 25.


Microfluidic affinity and ChIP-seq analyses converge on a conserved FOXP2-binding motif in chimp and human, which enables the detection of evolutionarily novel targets.

Nelson CS, Fuller CK, Fordyce PM, Greninger AL, Li H, DeRisi JL.

Nucleic Acids Res. 2013 Jul;41(12):5991-6004. doi: 10.1093/nar/gkt259. Epub 2013 Apr 26.


Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains.

Lohse MB, Hernday AD, Fordyce PM, Noiman L, Sorrells TR, Hanson-Smith V, Nobile CJ, DeRisi JL, Johnson AD.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7660-5. doi: 10.1073/pnas.1221734110. Epub 2013 Apr 22.


Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses.

Fordyce PM, Pincus D, Kimmig P, Nelson CS, El-Samad H, Walter P, DeRisi JL.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3084-93. doi: 10.1073/pnas.1212457109. Epub 2012 Oct 10.


Programmable microfluidic synthesis of spectrally encoded microspheres.

Gerver RE, Gómez-Sjöberg R, Baxter BC, Thorn KS, Fordyce PM, Diaz-Botia CA, Helms BA, DeRisi JL.

Lab Chip. 2012 Nov 21;12(22):4716-23. doi: 10.1039/c2lc40699c. Erratum in: Lab Chip. 2015 Feb 21;15(4):1213.


Systematic characterization of feature dimensions and closing pressures for microfluidic valves produced via photoresist reflow.

Fordyce PM, Diaz-Botia CA, DeRisi JL, Gomez-Sjoberg R.

Lab Chip. 2012 Nov 7;12(21):4287-95. doi: 10.1039/c2lc40414a.


De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis.

Fordyce PM, Gerber D, Tran D, Zheng J, Li H, DeRisi JL, Quake SR.

Nat Biotechnol. 2010 Sep;28(9):970-5. doi: 10.1038/nbt.1675. Epub 2010 Aug 29.


Eg5 steps it up!

Valentine MT, Fordyce PM, Block SM.

Cell Div. 2006 Dec 15;1:31.


Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro.

Valentine MT, Fordyce PM, Krzysiak TC, Gilbert SP, Block SM.

Nat Cell Biol. 2006 May;8(5):470-6. Epub 2006 Apr 2.


Simultaneous, coincident optical trapping and single-molecule fluorescence.

Lang MJ, Fordyce PM, Engh AM, Neuman KC, Block SM.

Nat Methods. 2004 Nov;1(2):133-9. Epub 2004 Oct 21.


Combined optical trapping and single-molecule fluorescence.

Lang MJ, Fordyce PM, Block SM.

J Biol. 2003;2(1):6. Epub 2003 Feb 24.


Stepping and stretching. How kinesin uses internal strain to walk processively.

Rosenfeld SS, Fordyce PM, Jefferson GM, King PH, Block SM.

J Biol Chem. 2003 May 16;278(20):18550-6. Epub 2003 Mar 6.


Search for the decay KL --> pi(0)e+e-.

Alavi-Harati A, Albuquerque IF, Alexopoulos T, Arenton M, Arisaka K, Averitte S, Barker AR, Bellantoni L, Bellavance A, Belz J, Ben-David R, Bergman DR, Blucher E, Bock GJ, Bown C, Bright S, Cheu E, Childress S, Coleman R, Corcoran MD, Corti G, Cox B, Crisler MB, Erwin AR, Ford R, Fordyce PM, Glazov A, Golossanov A, Graham G, Graham J, Hagan K, Halkiadakis E, Hanagaki K, Hidaka S, Hsiung YB, Jejer V, Jennings J, Jensen DA, Kessler R, Kobrak HG, LaDue J, Lath A, Ledovskoy A, McBride PL, McManus AP, Mikelsons P, Monnier E, Nakaya T, Nelson KS, Nguyen H, O'Dell V, Pang M, Pordes R, Prasad V, Qiao C, Quinn B, Ramberg EJ, Ray RE, Roodman A, Sadamoto M, Schnetzer S, Senyo K, Shanahan P, Shawhan PS, Slater W, Solomey N, Somalwar SV, Stone RL, Suzuki I, Swallow EC, Swanson RA, Taegar SA, Tesarek RJ, Thomson GB, Toale PA, Tripathi A, Tschirhart R, Wah YW, Wang J, White HB, Whitmore J, Winstein B, Winston R, Yamanaka T, Zimmerman ED.

Phys Rev Lett. 2001 Jan 15;86(3):397-401.


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