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Items: 8

1.

Activity Based Profiling of Deubiquitylating Enzymes and Inhibitors in Animal Tissues.

McLellan L, Forder C, Cranston A, Harrigan J, Jacq X.

Methods Mol Biol. 2016;1449:411-9. doi: 10.1007/978-1-4939-3756-1_27.

PMID:
27613053
2.

AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.

Byth KF, Thomas A, Hughes G, Forder C, McGregor A, Geh C, Oakes S, Green C, Walker M, Newcombe N, Green S, Growcott J, Barker A, Wilkinson RW.

Mol Cancer Ther. 2009 Jul;8(7):1856-66. doi: 10.1158/1535-7163.MCT-08-0836. Epub 2009 Jun 9.

3.

Discovery of imidazole vinyl pyrimidines as a novel class of kinase inhibitors which inhibit Tie-2 and are orally bioavailable.

Buttar D, Edge M, Emery SC, Fitzek M, Forder C, Griffen A, Hayter B, Hayward CF, Hopcroft PJ, Luke RW, Page K, Stawpert J, Wright A.

Bioorg Med Chem Lett. 2008 Aug 15;18(16):4723-6. doi: 10.1016/j.bmcl.2008.06.106. Epub 2008 Jul 23.

PMID:
18676144
4.

A phase I pharmacodynamic study of the effects of the cyclin-dependent kinase-inhibitor AZD5438 on cell cycle markers within the buccal mucosa, plucked scalp hairs and peripheral blood mononucleocytes of healthy male volunteers.

Camidge DR, Pemberton M, Growcott J, Amakye D, Wilson D, Swaisland H, Forder C, Wilkinson R, Byth K, Hughes A.

Cancer Chemother Pharmacol. 2007 Sep;60(4):479-88. Epub 2006 Dec 2.

PMID:
17143601
5.

The cellular phenotype of AZ703, a novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor.

Byth KF, Geh C, Forder CL, Oakes SE, Thomas AP.

Mol Cancer Ther. 2006 Mar;5(3):655-64.

6.

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

Marron MB, Hughes DP, Edge MD, Forder CL, Brindle NP.

J Biol Chem. 2000 Dec 15;275(50):39741-6.

7.

Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L-glutamic acid: reversed-polarity mutants.

Edge M, Forder C, Hennam J, Lee I, Tonge D, Hardern I, Fitton J, Eckersley K, East S, Shufflebotham A, Blakey D, Slater A.

Protein Eng. 1998 Dec;11(12):1229-34.

PMID:
9930672
8.

Abortion: a constitutional problem in European perspective.

Forder CJ.

Maastrich J Eur Comp Law. 1994;1:56-100. No abstract available.

PMID:
11656792

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