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Items: 4

1.

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF.

PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov.

2.

Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics.

Crusco A, Whiteland H, Baptista R, Forde-Thomas JE, Beckmann M, Mur LAJ, Nash RJ, Westwell AD, Hoffmann KF.

ACS Infect Dis. 2019 Jul 12;5(7):1188-1199. doi: 10.1021/acsinfecdis.9b00034. Epub 2019 May 28.

PMID:
31083889
3.

An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni.

Whiteland HL, Chakroborty A, Forde-Thomas JE, Crusco A, Cookson A, Hollinshead J, Fenn CA, Bartholomew B, Holdsworth PA, Fisher M, Nash RJ, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):465-474. doi: 10.1016/j.ijpddr.2018.10.009. Epub 2018 Oct 26.

4.

Aberrant spindle dynamics and cytokinesis in Dictyostelium discoideum cells that lack glycogen synthase kinase 3.

Harwood AJ, Forde-Thomas JE, Williams H, Samereier M, Müller-Taubenberger A.

Eur J Cell Biol. 2013 Jun-Jul;92(6-7):222-8. doi: 10.1016/j.ejcb.2013.05.001. Epub 2013 May 16.

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