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Items: 1 to 50 of 125

1.

Haematopoietic stem cells in cirrhosis - Authors' reply.

Newsome PN, Fox R, Forbes SJ.

Lancet Gastroenterol Hepatol. 2018 May;3(5):298-299. doi: 10.1016/S2468-1253(18)30035-9. Epub 2018 Apr 6. No abstract available.

PMID:
29644971
2.

Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ.

Nature. 2018 Mar 14;555(7696):402. doi: 10.1038/nature25996.

PMID:
29542689
3.

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.

Ferreira-Gonzalez S, Lu WY, Raven A, Dwyer B, Man TY, O'Duibhir E, Lewis PJS, Campana L, Kendall TJ, Bird TG, Tarrats N, Acosta JC, Boulter L, Forbes SJ.

Nat Commun. 2018 Mar 9;9(1):1020. doi: 10.1038/s41467-018-03299-5.

4.

Studies of macrophage therapy for cirrhosis - From mice to men.

Thomas JA, Ramachandran P, Forbes SJ.

J Hepatol. 2018 May;68(5):1090-1091. doi: 10.1016/j.jhep.2017.11.043. Epub 2018 Jan 6. No abstract available.

PMID:
29317297
5.

Understanding liver regeneration to bring new insights to the mechanisms driving cholangiocarcinoma.

Guest RV, Boulter L, Dwyer BJ, Forbes SJ.

NPJ Regen Med. 2017 May 22;2:13. doi: 10.1038/s41536-017-0018-z. eCollection 2017.

6.

Raman spectroscopy and regenerative medicine: a review.

Ember KJI, Hoeve MA, McAughtrie SL, Bergholt MS, Dwyer BJ, Stevens MM, Faulds K, Forbes SJ, Campbell CJ.

NPJ Regen Med. 2017 May 15;2:12. doi: 10.1038/s41536-017-0014-3. eCollection 2017. Review.

7.

GADD45β Loss Ablates Innate Immunosuppression in Cancer.

Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, Forbes SJ, Sica A, Alesse E, Zazzeroni F, Franzoso G.

Cancer Res. 2018 Mar 1;78(5):1275-1292. doi: 10.1158/0008-5472.CAN-17-1833. Epub 2017 Dec 26.

PMID:
29279355
8.

The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.

Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP.

J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20.

PMID:
29263216
9.

11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.

Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z.

Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22.

10.

Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial.

Newsome PN, Fox R, King AL, Barton D, Than NN, Moore J, Corbett C, Townsend S, Thomas J, Guo K, Hull D, Beard HA, Thompson J, Atkinson A, Bienek C, McGowan N, Guha N, Campbell J, Hollyman D, Stocken D, Yap C, Forbes SJ.

Lancet Gastroenterol Hepatol. 2018 Jan;3(1):25-36. doi: 10.1016/S2468-1253(17)30326-6. Epub 2017 Nov 7.

11.

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ.

Nature. 2017 Jul 20;547(7663):350-354. doi: 10.1038/nature23015. Epub 2017 Jul 12. Erratum in: Nature. 2018 Mar 14;555(7696):402.

12.

Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.

Fraser AR, Pass C, Burgoyne P, Atkinson A, Bailey L, Laurie A, W A McGowan N, Hamid A, Moore JK, Dwyer BJ, Turner ML, Forbes SJ, Campbell JDM.

Cytotherapy. 2017 Sep;19(9):1113-1124. doi: 10.1016/j.jcyt.2017.05.009. Epub 2017 Jun 30.

13.

Milk Fat Globule-EGF Factor 8 for Liver Fibrosis Therapy: Creaming Off the Beneficial Effects of Mesenchymal Stromal Cells.

Forbes SJ.

Gastroenterology. 2017 Apr;152(5):943-946. doi: 10.1053/j.gastro.2017.02.032. Epub 2017 Mar 1. No abstract available.

PMID:
28259796
14.

Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labeling in macrophages for magnetic resonance-based detection in vivo.

Sharkey J, Starkey Lewis PJ, Barrow M, Alwahsh SM, Noble J, Livingstone E, Lennen RJ, Jansen MA, Carrion JG, Liptrott N, Forbes S, Adams DJ, Chadwick AE, Forbes SJ, Murray P, Rosseinsky MJ, Goldring CE, Park BK.

Cytotherapy. 2017 Apr;19(4):555-569. doi: 10.1016/j.jcyt.2017.01.003. Epub 2017 Feb 15.

15.

Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference.

Abou-Alfa GK, Andersen JB, Chapman W, Choti M, Forbes SJ, Gores GJ, Hong TS, Harding JJ, Vander Heiden MG, Javle M, Kelley RK, Kwong LN, Lowery M, Merrell A, Miyabe K, Rhim A, Saha S, Sia D, Tanasanvimon S, Venook A, Valle JW, Walesky C, Whetstine J, Willenbring H, Zhu AX, Mayer D, Stanger BZ.

J Gastrointest Oncol. 2016 Dec;7(6):819-827. doi: 10.21037/jgo.2016.11.11. No abstract available.

16.

Increased pollinator habitat enhances cacao fruit set and predator conservation.

Forbes SJ, Northfield TD.

Ecol Appl. 2017 Apr;27(3):887-899. doi: 10.1002/eap.1491. Epub 2017 Mar 15.

PMID:
28019052
17.

Patients with the worst outcomes after paracetamol (acetaminophen)-induced liver failure have an early monocytopenia.

Moore JK, MacKinnon AC, Man TY, Manning JR, Forbes SJ, Simpson KJ.

Aliment Pharmacol Ther. 2017 Feb;45(3):443-454. doi: 10.1111/apt.13878. Epub 2016 Nov 28.

PMID:
27896824
18.

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells.

Oosthuyzen W, Scullion KM, Ivy JR, Morrison EE, Hunter RW, Starkey Lewis PJ, O'Duibhir E, Street JM, Caporali A, Gregory CD, Forbes SJ, Webb DJ, Bailey MA, Dear JW.

J Am Soc Nephrol. 2016 Nov;27(11):3345-3355. Epub 2016 Mar 28.

19.

Notch3 drives development and progression of cholangiocarcinoma.

Guest RV, Boulter L, Dwyer BJ, Kendall TJ, Man TY, Minnis-Lyons SE, Lu WY, Robson AJ, Gonzalez SF, Raven A, Wojtacha D, Morton JP, Komuta M, Roskams T, Wigmore SJ, Sansom OJ, Forbes SJ.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12250-12255. Epub 2016 Oct 10.

20.

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 Oct 27;18(11):1260. doi: 10.1038/ncb3428. No abstract available.

PMID:
27784900
21.

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers.

Carotenuto P, Fassan M, Pandolfo R, Lampis A, Vicentini C, Cascione L, Paulus-Hock V, Boulter L, Guest R, Quagliata L, Hahne JC, Ridgway R, Jamieson T, Athineos D, Veronese A, Visone R, Murgia C, Ferrari G, Guzzardo V, Evans TRJ, MacLeod M, Feng GJ, Dale T, Negrini M, Forbes SJ, Terracciano L, Scarpa A, Patel T, Valeri N, Workman P, Sansom O, Braconi C.

Gut. 2017 Jul;66(7):1268-1277. doi: 10.1136/gutjnl-2016-312278. Epub 2016 Sep 12.

22.

Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis.

Gieseck RL 3rd, Ramalingam TR, Hart KM, Vannella KM, Cantu DA, Lu WY, Ferreira-González S, Forbes SJ, Vallier L, Wynn TA.

Immunity. 2016 Jul 19;45(1):145-58. doi: 10.1016/j.immuni.2016.06.009. Epub 2016 Jul 12.

23.

Liver regeneration - mechanisms and models to clinical application.

Forbes SJ, Newsome PN.

Nat Rev Gastroenterol Hepatol. 2016 Aug;13(8):473-85. doi: 10.1038/nrgastro.2016.97. Epub 2016 Jun 29. Review.

PMID:
27353402
24.

Corrigendum to "Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma" [J Hepatol 2015;62:607-616].

Yeung OW, Lo CM, Ling CC, Qi X, Geng W, Li CX, Ng KT, Forbes SJ, Guan XY, Poon RT, Fan ST, Man K.

J Hepatol. 2016 Jun;64(6):1461. doi: 10.1016/j.jhep.2016.02.038. Epub 2016 Mar 16. No abstract available.

PMID:
27198050
25.

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D.

Nat Rev Gastroenterol Hepatol. 2016 May;13(5):261-80. doi: 10.1038/nrgastro.2016.51. Epub 2016 Apr 20.

26.

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 May;18(5):467-79. doi: 10.1038/ncb3337. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2016 Oct 27;18(11):1260.

PMID:
27088858
27.

Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.

Szkolnicka D, Lucendo-Villarin B, Moore JK, Simpson KJ, Forbes SJ, Hay DC.

Stem Cells Transl Med. 2016 Jun;5(6):764-72. doi: 10.5966/sctm.2015-0117. Epub 2016 Apr 7.

28.

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes.

Cameron K, Tan R, Schmidt-Heck W, Campos G, Lyall MJ, Wang Y, Lucendo-Villarin B, Szkolnicka D, Bates N, Kimber SJ, Hengstler JG, Godoy P, Forbes SJ, Hay DC.

Stem Cell Reports. 2015 Dec 8;5(6):1250-1262. doi: 10.1016/j.stemcr.2015.10.016. Epub 2015 Nov 25.

29.

Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.

Muir KR, Lima MJ, Docherty HM, McGowan NW, Forbes S, Heremans Y, Forbes SJ, Heimberg H, Casey J, Docherty K.

PLoS One. 2015 Oct 12;10(10):e0140352. doi: 10.1371/journal.pone.0140352. eCollection 2015.

30.

Two Fresh Streams to Fill the Liver's Hepatocyte Pool.

Bird TG, Forbes SJ.

Cell Stem Cell. 2015 Oct 1;17(4):377-8. doi: 10.1016/j.stem.2015.09.007.

31.

CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure.

Stutchfield BM, Antoine DJ, Mackinnon AC, Gow DJ, Bain CC, Hawley CA, Hughes MJ, Francis B, Wojtacha D, Man TY, Dear JW, Devey LR, Mowat AM, Pollard JW, Park BK, Jenkins SJ, Simpson KJ, Hume DA, Wigmore SJ, Forbes SJ.

Gastroenterology. 2015 Dec;149(7):1896-1909.e14. doi: 10.1053/j.gastro.2015.08.053. Epub 2015 Sep 5.

32.

Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.

Moore JK, Mackinnon AC, Wojtacha D, Pope C, Fraser AR, Burgoyne P, Bailey L, Pass C, Atkinson A, Mcgowan NW, Manson L, Turner ML, Campbell JD, Forbes SJ.

Cytotherapy. 2015 Nov;17(11):1604-16. doi: 10.1016/j.jcyt.2015.07.016. Epub 2015 Sep 3.

33.

Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015).

Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M, Hay DC.

Adv Healthc Mater. 2015 Aug 26;4(12):1819. doi: 10.1002/adhm.201570072.

PMID:
26308957
34.

Hepatic progenitor cells of biliary origin with liver repopulation capacity.

Lu WY, Bird TG, Boulter L, Tsuchiya A, Cole AM, Hay T, Guest RV, Wojtacha D, Man TY, Mackinnon A, Ridgway RA, Kendall T, Williams MJ, Jamieson T, Raven A, Hay DC, Iredale JP, Clarke AR, Sansom OJ, Forbes SJ.

Nat Cell Biol. 2015 Aug;17(8):971-983. doi: 10.1038/ncb3203. Epub 2015 Jul 20.

35.

Organoid cultures boost human liver cell expansion.

Forbes SJ.

Hepatology. 2015 Nov;62(5):1635-7. doi: 10.1002/hep.27970. Epub 2015 Jul 31. No abstract available.

PMID:
26146934
36.

Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.

Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M, Hay DC.

Adv Healthc Mater. 2015 Aug 26;4(12):1820-5. doi: 10.1002/adhm.201500391. Epub 2015 Jun 24.

PMID:
26109270
37.

Cell therapy for liver disease: From liver transplantation to cell factory.

Forbes SJ, Gupta S, Dhawan A.

J Hepatol. 2015 Apr;62(1 Suppl):S157-69. doi: 10.1016/j.jhep.2015.02.040. Review.

38.
39.

WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.

Boulter L, Guest RV, Kendall TJ, Wilson DH, Wojtacha D, Robson AJ, Ridgway RA, Samuel K, Van Rooijen N, Barry ST, Wigmore SJ, Sansom OJ, Forbes SJ.

J Clin Invest. 2015 Mar 2;125(3):1269-85. doi: 10.1172/JCI76452. Epub 2015 Feb 17.

40.

Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma.

Yeung OW, Lo CM, Ling CC, Qi X, Geng W, Li CX, Ng KT, Forbes SJ, Guan XY, Poon RT, Fan ST, Man K.

J Hepatol. 2015 Mar;62(3):607-16. doi: 10.1016/j.jhep.2014.10.029. Epub 2014 Oct 30.

PMID:
25450711
41.

Preparing the ground for tissue regeneration: from mechanism to therapy.

Forbes SJ, Rosenthal N.

Nat Med. 2014 Aug;20(8):857-69. doi: 10.1038/nm.3653. Review.

PMID:
25100531
42.

Galectin-3 regulates hepatic progenitor cell expansion during liver injury.

Hsieh WC, Mackinnon AC, Lu WY, Jung J, Boulter L, Henderson NC, Simpson KJ, Schotanus B, Wojtacha D, Bird TG, Medine CN, Hay DC, Sethi T, Iredale JP, Forbes SJ.

Gut. 2015 Feb;64(2):312-21. doi: 10.1136/gutjnl-2013-306290. Epub 2014 May 16.

PMID:
24837171
43.

Regenerative medicine. Knocking on the door to successful hepatocyte transplantation.

Forbes SJ, Alison MR.

Nat Rev Gastroenterol Hepatol. 2014 May;11(5):277-8. doi: 10.1038/nrgastro.2014.44. Epub 2014 Mar 25.

PMID:
24662276
44.

Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome.

Craig DG, Lee P, Pryde EA, Hidalgo E, Hayes PC, Wigmore SJ, Forbes SJ, Simpson KJ.

Case Rep Transplant. 2014;2014:272498. doi: 10.1155/2014/272498. Epub 2014 Jan 29.

45.

Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.

Tsuchiya A, Lu WY, Weinhold B, Boulter L, Stutchfield BM, Williams MJ, Guest RV, Minnis-Lyons SE, MacKinnon AC, Schwarzer D, Ichida T, Nomoto M, Aoyagi Y, Gerardy-Schahn R, Forbes SJ.

Hepatology. 2014 Nov;60(5):1727-40. doi: 10.1002/hep.27099. Epub 2014 Sep 29.

PMID:
24585441
46.

Systematic review: the effects of autologous stem cell therapy for patients with liver disease.

Moore JK, Stutchfield BM, Forbes SJ.

Aliment Pharmacol Ther. 2014 Apr;39(7):673-85. doi: 10.1111/apt.12645. Epub 2014 Feb 13. Review.

47.

Recent advances in stem cells and regenerative medicine.

Forbes SJ.

QJM. 2014 Apr;107(4):251-2. doi: 10.1093/qjmed/hcu032. Epub 2014 Feb 6. No abstract available.

48.

Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.

Kallis YN, Scotton CJ, Mackinnon AC, Goldin RD, Wright NA, Iredale JP, Chambers RC, Forbes SJ.

PLoS One. 2014 Jan 27;9(1):e86241. doi: 10.1371/journal.pone.0086241. eCollection 2014.

49.

CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist.

Sarvi S, Mackinnon AC, Avlonitis N, Bradley M, Rintoul RC, Rassl DM, Wang W, Forbes SJ, Gregory CD, Sethi T.

Cancer Res. 2014 Mar 1;74(5):1554-65. doi: 10.1158/0008-5472.CAN-13-1541. Epub 2014 Jan 16.

50.

Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion.

Williams MJ, Clouston AD, Forbes SJ.

Gastroenterology. 2014 Feb;146(2):349-56. doi: 10.1053/j.gastro.2013.11.034. Epub 2013 Dec 4. Review.

PMID:
24315991

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