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Items: 1 to 50 of 60

1.

Heterodimerization of the GABAB receptor-implications for GPCR signaling and drug discovery.

Marshall FH, Foord SM.

Adv Pharmacol. 2010;58:63-91. doi: 10.1016/S1054-3589(10)58003-7. Review.

PMID:
20655478
2.

Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery.

Barnes MR, Harland L, Foord SM, Hall MD, Dix I, Thomas S, Williams-Jones BI, Brouwer CR.

Nat Rev Drug Discov. 2009 Sep;8(9):701-8. doi: 10.1038/nrd2944. Epub 2009 Jul 17. Review.

PMID:
19609266
3.

Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design.

Gloriam DE, Foord SM, Blaney FE, Garland SL.

J Med Chem. 2009 Jul 23;52(14):4429-42. doi: 10.1021/jm900319e.

PMID:
19537715
4.

International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.

Maguire JJ, Parker WA, Foord SM, Bonner TI, Neubig RR, Davenport AP.

Pharmacol Rev. 2009 Mar;61(1):1-8. doi: 10.1124/pr.109.001107. Review.

5.

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents.

Haitina T, Fredriksson R, Foord SM, Schiöth HB, Gloriam DE.

BMC Genomics. 2009 Jan 15;10:24. doi: 10.1186/1471-2164-10-24.

6.

IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.

Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, Catterall WA, Davenport AP, Delagrange P, Dollery CT, Foord SM, Gutman GA, Laudet V, Neubig RR, Ohlstein EH, Olsen RW, Peters J, Pin JP, Ruffolo RR, Searls DB, Wright MW, Spedding M.

Nucleic Acids Res. 2009 Jan;37(Database issue):D680-5. doi: 10.1093/nar/gkn728. Epub 2008 Oct 23.

7.

The role of positive selection in determining the molecular cause of species differences in disease.

Vamathevan JJ, Hasan S, Emes RD, Amrine-Madsen H, Rajagopalan D, Topp SD, Kumar V, Word M, Simmons MD, Foord SM, Sanseau P, Yang Z, Holbrook JD.

BMC Evol Biol. 2008 Oct 6;8:273. doi: 10.1186/1471-2148-8-273.

8.

Drug discovery in the extracellular matrix.

Huxley-Jones J, Foord SM, Barnes MR.

Drug Discov Today. 2008 Aug;13(15-16):685-94. doi: 10.1016/j.drudis.2008.05.005. Epub 2008 Jun 24. Review.

PMID:
18583179
9.

International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function.

Davenport AP, Bonner TI, Foord SM, Harmar AJ, Neubig RR, Pin JP, Spedding M, Kojima M, Kangawa K.

Pharmacol Rev. 2005 Dec;57(4):541-6. Review.

PMID:
16382107
10.

New methods for researching accessory proteins.

Foord SM, Topp SD, Abramo M, Holbrook JD.

J Mol Neurosci. 2005;26(2-3):265-76. Review.

PMID:
16012200
11.

International Union of Pharmacology. XLVI. G protein-coupled receptor list.

Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin JP, Davenport AP, Spedding M, Harmar AJ.

Pharmacol Rev. 2005 Jun;57(2):279-88. Review.

PMID:
15914470
12.

Current status of drug receptor nomenclature: receptor closure? The role of NC-IUPHAR.

Spedding M, Foord SM, Hofmann F.

Expert Opin Investig Drugs. 2004 May;13(5):461-4.

PMID:
15155121
13.

Matching accessories.

Foord SM.

Sci STKE. 2003 Jul 8;2003(190):pe25. Review.

PMID:
12855771
14.

Important amino acids for the function of the human MT1 melatonin receptor.

Kokkola T, Foord SM, Watson MA, Vakkuri O, Laitinen JT.

Biochem Pharmacol. 2003 May 1;65(9):1463-71.

PMID:
12732358
15.

Molecular identification of high and low affinity receptors for nicotinic acid.

Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB.

J Biol Chem. 2003 Mar 14;278(11):9869-74. Epub 2003 Jan 9.

16.

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ.

J Biol Chem. 2003 Mar 28;278(13):11312-9. Epub 2002 Dec 19.

17.

Receptor classification: post genome.

Foord SM.

Curr Opin Pharmacol. 2002 Oct;2(5):561-6. Review.

PMID:
12324260
18.

Bioinformatics and type II G-protein-coupled receptors.

Foord SM, Jupe S, Holbrook J.

Biochem Soc Trans. 2002 Aug;30(4):473-9. Review.

PMID:
12196118
19.

International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.

Poyner DR, Sexton PM, Marshall I, Smith DM, Quirion R, Born W, Muff R, Fischer JA, Foord SM.

Pharmacol Rev. 2002 Jun;54(2):233-46. Review.

PMID:
12037140
20.

Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.

Hilairet S, Bélanger C, Bertrand J, Laperrière A, Foord SM, Bouvier M.

J Biol Chem. 2001 Nov 9;276(45):42182-90. Epub 2001 Sep 4.

22.

Transgenic gene knock-outs: functional genomics and therapeutic target selection.

Harris S, Foord SM.

Pharmacogenomics. 2000 Nov;1(4):433-43. Review.

PMID:
11257927
23.

The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor.

Foord SM, Wise A, Brown J, Main MJ, Fraser NJ.

Biochem Soc Trans. 1999 Aug;27(4):535-9. Review. No abstract available.

PMID:
10917636
24.
25.

Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product.

Zumpe ET, Tilakaratne N, Fraser NJ, Christopoulos G, Foord SM, Sexton PM.

Biochem Biophys Res Commun. 2000 Jan 7;267(1):368-72.

PMID:
10623626
26.

Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product.

Christopoulos G, Perry KJ, Morfis M, Tilakaratne N, Gao Y, Fraser NJ, Main MJ, Foord SM, Sexton PM.

Mol Pharmacol. 1999 Jul;56(1):235-42.

PMID:
10385705
27.

RAMPs: accessory proteins for seven transmembrane domain receptors.

Foord SM, Marshall FH.

Trends Pharmacol Sci. 1999 May;20(5):184-7. Review. No abstract available.

PMID:
10354609
28.
29.

Receptor activity modifying proteins regulate the activity of a calcitonin gene-related peptide receptor in rabbit aortic endothelial cells.

Muff R, Leuthäuser K, Bühlmann N, Foord SM, Fischer JA, Born W.

FEBS Lett. 1998 Dec 28;441(3):366-8.

30.

The CGRP receptor can couple via pertussis toxin sensitive and insensitive G proteins.

Main MJ, Brown J, Brown S, Fraser NJ, Foord SM.

FEBS Lett. 1998 Dec 11;441(1):6-10.

31.

Heterodimerization is required for the formation of a functional GABA(B) receptor.

White JH, Wise A, Main MJ, Green A, Fraser NJ, Disney GH, Barnes AA, Emson P, Foord SM, Marshall FH.

Nature. 1998 Dec 17;396(6712):679-82.

PMID:
9872316
32.

Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function.

Kokkola T, Watson MA, White J, Dowell S, Foord SM, Laitinen JT.

Biochem Biophys Res Commun. 1998 Aug 19;249(2):531-6.

PMID:
9712731
33.

GR196429: a nonindolic agonist at high-affinity melatonin receptors.

Beresford IJ, Browning C, Starkey SJ, Brown J, Foord SM, Coughlan J, North PC, Dubocovich ML, Hagan RM.

J Pharmacol Exp Ther. 1998 Jun;285(3):1239-45.

PMID:
9618428
34.

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM.

Nature. 1998 May 28;393(6683):333-9.

PMID:
9620797
35.

Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus.

Marshall FH, Patel K, Lundstrom K, Camacho J, Foord SM, Lee MG.

Br J Pharmacol. 1997 Aug;121(8):1673-8.

36.

The structure of the prostaglandin EP4 receptor gene and related pseudogenes.

Foord SM, Marks B, Stolz M, Bufflier E, Fraser NJ, Lee MG.

Genomics. 1996 Jul 1;35(1):182-8.

PMID:
8661119
37.

Isolation and characterisation of a human calcitonin-gene-related-peptide receptor.

Foord SM, Craig RK.

Eur J Biochem. 1987 Dec 30;170(1-2):373-9.

38.
39.

Thyrotropin regulates thyrotroph responsiveness to dopamine in vitro.

Foord SM, Peters JR, Dieguez C, Shewring G, Hall R, Scanlon MF.

Endocrinology. 1986 Apr;118(4):1319-26.

PMID:
3004910
40.

Expression and function of the human calcitonin/alpha-CGRP gene in health and disease.

Craig RK, Riley JH, Edbrooke MR, Broad PM, Foord SM, Al-Kazwini SJ, Holman JJ, Marshall I.

Biochem Soc Symp. 1986;52:91-105.

PMID:
3034287
41.

Differential production of SRIF 14 and 28 by fetal rat hypothalamic cells enriched by velocity sedimentation.

Lewis MD, Foord SM, Lewis MB, Hall R, Scanlon MF.

Neuroendocrinology. 1986;44(1):125-31.

PMID:
2878383
42.

Characterization and partial purification of the sodium-potassium-ATPase inhibitor released from cultured rat hypothalamic cells.

Morgan K, Lewis MD, Spurlock G, Collins PA, Foord SM, Southgate K, Scanlon MF, Mir MA.

J Biol Chem. 1985 Nov 5;260(25):13595-600.

43.

The influence of oestrogens on the sensitivity of PRL, TSH and LH to the inhibitory actions of dopamine in hyperprolactinaemic patients.

Valcavi R, Harris PE, Foord SM, Dieguez C, Evans PJ, Peters JR, Hall R, Scanlon MF.

Clin Endocrinol (Oxf). 1985 Aug;23(2):139-46.

PMID:
4053412
44.
45.

Differential effects of acute DA receptor blockade with domperidone on LH and TSH release in patients with hyperprolactinemia.

Peters JR, Rodriguez-Arnao MD, Foord SM, Edwards C, Dieguez C, Woodhead S, Hall R, Scanlon MF.

J Endocrinol Invest. 1985 Apr;8(2):163-6.

PMID:
4031383
46.

Relationships between the circadian rhythms of TSH, prolactin and cortisol in surgically treated microprolactinoma patients.

Salvador J, Wilson DW, Harris PE, Peters JR, Edwards C, Foord SM, Dieguez C, Hall R, Scanlon MF.

Clin Endocrinol (Oxf). 1985 Mar;22(3):265-72.

PMID:
3978833
48.

Release of an active sodium transport inhibitor (ASTI) from rat hypothalamic cells in culture.

Morgan K, Foord SM, Spurlock G, Charalambous BM, Dieguez C, Scanlon MF, Mir MA.

Endocrinology. 1984 Oct;115(4):1642-4.

PMID:
6148236
49.

Rat anterior pituitary cells maintained on artificial capillaries: responses of thyrotrophs and lactotrophs to depolarization, TRH and dopamine.

Dieguez C, Foord SM, Newman GR, Shewring G, Hall R, Jackson IM, Peters JR, Scanlon MF.

Mol Cell Endocrinol. 1984 Aug;37(1):73-82.

PMID:
6432605
50.

Hypothyroid pituitary cells in culture: an analysis of thyrotropin and prolactin responses to dopamine (DA) and DA receptor binding.

Foord SM, Peters JR, Dieguez C, Jasani B, Hall R, Scanlon MF.

Endocrinology. 1984 Jul;115(1):407-15.

PMID:
6428863

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