Sort by
Items per page

Send to

Choose Destination

Search results

Items: 29


Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli.

Caveney NA, Caballero G, Voedts H, Niciforovic A, Worrall LJ, Vuckovic M, Fonvielle M, Hugonnet JE, Arthur M, Strynadka NCJ.

Nat Commun. 2019 Apr 23;10(1):1849. doi: 10.1038/s41467-019-09507-0.


Negative Impact of Carbapenem Methylation on the Reactivity of β-Lactams for Cysteine Acylation as Revealed by Quantum Calculations and Kinetic Analyses.

Bhattacharjee N, Triboulet S, Dubée V, Fonvielle M, Edoo Z, Hugonnet JE, Ethève-Quelquejeu M, Simorre JP, Field MJ, Arthur M, Bougault CM.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02039-18. doi: 10.1128/AAC.02039-18. Print 2019 Apr.


Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus.

Maya-Martinez R, Alexander JAN, Otten CF, Ayala I, Vollmer D, Gray J, Bougault CM, Burt A, Laguri C, Fonvielle M, Arthur M, Strynadka NCJ, Vollmer W, Simorre JP.

Front Microbiol. 2019 Jan 18;9:3223. doi: 10.3389/fmicb.2018.03223. eCollection 2018.


Synthesis of Lipid-Carbohydrate-Peptidyl-RNA Conjugates to Explore the Limits Imposed by the Substrate Specificity of Cell Wall Enzymes on the Acquisition of Drug Resistance.

Fonvielle M, Bouhss A, Hoareau C, Patin D, Mengin-Lecreulx D, Iannazzo L, Sakkas N, El Sagheer A, Brown T, Ethève-Quelquejeu M, Arthur M.

Chemistry. 2018 Oct 9;24(56):14911-14915. doi: 10.1002/chem.201802360. Epub 2018 Sep 6.


Synthesis of Avibactam Derivatives and Activity on β-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria.

Edoo Z, Iannazzo L, Compain F, Li de la Sierra Gallay I, van Tilbeurgh H, Fonvielle M, Bouchet F, Le Run E, Mainardi JL, Arthur M, Ethève-Quelquejeu M, Hugonnet JE.

Chemistry. 2018 Jun 7;24(32):8081-8086. doi: 10.1002/chem.201800923. Epub 2018 May 14.


Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.

Iannazzo L, Fonvielle M, Braud E, Hřebabecký H, Procházková E, Nencka R, Mathé C, Arthur M, Etheve-Quelquejeu M.

Org Biomol Chem. 2018 Mar 14;16(11):1903-1911. doi: 10.1039/c8ob00019k.


Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d-Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis.

Ngadjeua F, Braud E, Saidjalolov S, Iannazzo L, Schnappinger D, Ehrt S, Hugonnet JE, Mengin-Lecreulx D, Patin D, Ethève-Quelquejeu M, Fonvielle M, Arthur M.

Chemistry. 2018 Apr 17;24(22):5743-5747. doi: 10.1002/chem.201706082. Epub 2018 Feb 21.


Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.

Fonvielle M, Sakkas N, Iannazzo L, Le Fournis C, Patin D, Mengin-Lecreulx D, El-Sagheer A, Braud E, Cardon S, Brown T, Arthur M, Etheve-Quelquejeu M.

Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13553-13557. doi: 10.1002/anie.201606843. Epub 2016 Sep 26.


Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC.

Iannazzo L, Soroka D, Triboulet S, Fonvielle M, Compain F, Dubée V, Mainardi JL, Hugonnet JE, Braud E, Arthur M, Etheve-Quelquejeu M.

J Med Chem. 2016 Apr 14;59(7):3427-38. doi: 10.1021/acs.jmedchem.6b00096. Epub 2016 Mar 18.


Synthesis of 3'-fluoro-tRNA analogues for exploring non-ribosomal peptide synthesis in bacteria.

Iannazzo L, Laisné G, Fonvielle M, Braud E, Herbeuval JP, Arthur M, Etheve-Quelquejeu M.

Chembiochem. 2015 Feb 9;16(3):477-86. doi: 10.1002/cbic.201402523. Epub 2015 Jan 13.


Synthesis of 3'-triazoyl-dinucleotides as precursors of stable Phe-tRNA(Phe) and Leu-tRNA(Leu) analogues.

Santarem M, Fonvielle M, Sakkas N, Laisné G, Chemama M, Herbeuval JP, Braud E, Arthur M, Etheve-Quelquejeu M.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3231-3. doi: 10.1016/j.bmcl.2014.06.027. Epub 2014 Jun 19.


Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei.

Moutiez M, Seguin J, Fonvielle M, Belin P, Jacques IB, Favry E, Arthur M, Gondry M.

Nucleic Acids Res. 2014 Jun;42(11):7247-58. doi: 10.1093/nar/gku348. Epub 2014 Apr 29.


Synthesis and biological evaluation of non-isomerizable analogues of Ala-tRNA(Ala).

Mellal D, Fonvielle M, Santarem M, Chemama M, Schneider Y, Iannazzo L, Braud E, Arthur M, Etheve-Quelquejeu M.

Org Biomol Chem. 2013 Sep 28;11(36):6161-9. doi: 10.1039/c3ob41206g.


The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors.

Fonvielle M, Li de La Sierra-Gallay I, El-Sagheer AH, Lecerf M, Patin D, Mellal D, Mayer C, Blanot D, Gale N, Brown T, van Tilbeurgh H, Ethève-Quelquejeu M, Arthur M.

Angew Chem Int Ed Engl. 2013 Jul 8;52(28):7278-81. doi: 10.1002/anie.201301411. Epub 2013 Jun 6. No abstract available.


Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121: insights from biochemical studies and crystal structures.

Fonvielle M, Le Du MH, Lequin O, Lecoq A, Jacquet M, Thai R, Dubois S, Grach G, Gondry M, Belin P.

J Biol Chem. 2013 Jun 14;288(24):17347-59. doi: 10.1074/jbc.M112.443853. Epub 2013 Apr 25.


Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase.

Fonvielle M, Mellal D, Patin D, Lecerf M, Blanot D, Bouhss A, Santarem M, Mengin-Lecreulx D, Sollogoub M, Arthur M, Ethève-Quelquejeu M.

Chemistry. 2013 Jan 21;19(4):1357-63. doi: 10.1002/chem.201201999. Epub 2012 Nov 29.


Nonribosomal peptide synthesis in animals: the cyclodipeptide synthase of Nematostella.

Seguin J, Moutiez M, Li Y, Belin P, Lecoq A, Fonvielle M, Charbonnier JB, Pernodet JL, Gondry M.

Chem Biol. 2011 Nov 23;18(11):1362-8. doi: 10.1016/j.chembiol.2011.09.010.


Synthesis of stable aminoacyl-tRNA analogs.

Chemama M, Fonvielle M, Lecerf M, Mellal D, Fief H, Arthur M, Etheve-Quelquejeu M.

Curr Protoc Nucleic Acid Chem. 2011 Mar;Chapter 4:Unit 4.44. doi: 10.1002/0471142700.nc0444s44.


Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis.

Sauguet L, Moutiez M, Li Y, Belin P, Seguin J, Le Du MH, Thai R, Masson C, Fonvielle M, Pernodet JL, Charbonnier JB, Gondry M.

Nucleic Acids Res. 2011 May;39(10):4475-89. doi: 10.1093/nar/gkr027. Epub 2011 Feb 3.


Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases.

Daher R, Coinçon M, Fonvielle M, Gest PM, Guerin ME, Jackson M, Sygusch J, Therisod M.

J Med Chem. 2010 Nov 11;53(21):7836-42. doi: 10.1021/jm1009814.


Decoding the logic of the tRNA regiospecificity of nonribosomal FemX(Wv) aminoacyl transferase.

Fonvielle M, Chemama M, Lecerf M, Villet R, Busca P, Bouhss A, Ethève-Quelquejeu M, Arthur M.

Angew Chem Int Ed Engl. 2010 Jul 12;49(30):5115-9. doi: 10.1002/anie.201001473. No abstract available.


Aminoacyl-tRNA recognition by the FemXWv transferase for bacterial cell wall synthesis.

Fonvielle M, Chemama M, Villet R, Lecerf M, Bouhss A, Valéry JM, Ethève-Quelquejeu M, Arthur M.

Nucleic Acids Res. 2009 Apr;37(5):1589-601. doi: 10.1093/nar/gkn1039. Epub 2009 Jan 16.


Synthesis of stable aminoacyl-tRNA analogues containing triazole as a bioisoster of esters.

Chemama M, Fonvielle M, Arthur M, Valéry JM, Etheve-Quelquejeu M.

Chemistry. 2009;15(8):1929-38. doi: 10.1002/chem.200801563.


Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics.

Fonvielle M, Coinçon M, Daher R, Desbenoit N, Kosieradzka K, Barilone N, Gicquel B, Sygusch J, Jackson M, Therisod M.

Chemistry. 2008;14(28):8521-9. doi: 10.1002/chem.200800857.


Idiosyncratic features in tRNAs participating in bacterial cell wall synthesis.

Villet R, Fonvielle M, Busca P, Chemama M, Maillard AP, Hugonnet JE, Dubost L, Marie A, Josseaume N, Mesnage S, Mayer C, Valéry JM, Ethève-Quelquejeu M, Arthur M.

Nucleic Acids Res. 2007;35(20):6870-83. Epub 2007 Oct 11.


Stable analogues of aminoacyl-tRNA for inhibition of an essential step of bacterial cell-wall synthesis.

Chemama M, Fonvielle M, Villet R, Arthur M, Valéry JM, Etheve-Quelquejeu M.

J Am Chem Soc. 2007 Oct 24;129(42):12642-3. Epub 2007 Oct 2. No abstract available. Erratum in: J Am Chem Soc. 2008 Mar 26;130(12):4203.


New competitive inhibitors of cytosolic (NADH-dependent) rabbit muscle glycerophosphate dehydrogenase.

Fonvielle M, Therisod H, Hemery M, Therisod M.

Bioorg Med Chem Lett. 2007 Jan 15;17(2):410-3. Epub 2006 Oct 17.


New inhibitors of rabbit muscle triose-phosphate isomerase.

Fonvielle M, Mariano S, Therisod M.

Bioorg Med Chem Lett. 2005 Jun 2;15(11):2906-9.


New highly selective inhibitors of class II fructose-1,6-bisphosphate aldolases.

Fonvielle M, Weber P, Dabkowska K, Therisod M.

Bioorg Med Chem Lett. 2004 Jun 7;14(11):2923-6.


Supplemental Content

Loading ...
Support Center