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Items: 1 to 50 of 62

1.

A phase 2 clinical trial of a vasopressin V1a receptor antagonist shows improved adaptive behaviors in men with autism spectrum disorder.

Bolognani F, Del Valle Rubido M, Squassante L, Wandel C, Derks M, Murtagh L, Sevigny J, Khwaja O, Umbricht D, Fontoura P.

Sci Transl Med. 2019 May 8;11(491). pii: eaat7838. doi: 10.1126/scitranslmed.aat7838. Epub 2019 May 1.

PMID:
31043521
2.

In Search of Biomarkers for Autism Spectrum Disorder.

Del Valle Rubido M, McCracken JT, Hollander E, Shic F, Noeldeke J, Boak L, Khwaja O, Sadikhov S, Fontoura P, Umbricht D.

Autism Res. 2018 Nov;11(11):1567-1579. doi: 10.1002/aur.2026. Epub 2018 Oct 15.

3.

Marine tardigrades of the Bahamas with the description of two new species and updated keys to the species of Anisonyches and Archechiniscus.

Bartels PJ, Fontoura P, Nelson DR.

Zootaxa. 2018 May 14;4420(1):43-70. doi: 10.11646/zootaxa.4420.1.3.

PMID:
30313553
4.

Correction to: A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.

Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators.

Alzheimers Res Ther. 2018 Sep 27;10(1):99. doi: 10.1186/s13195-018-0409-4.

5.

Survey of Third-Party Parenting Options Associated With Fertility Preservation Available to Patients With Cancer Around the Globe.

Rashedi AS, de Roo SF, Ataman LM, Edmonds ME, Silva AA, Scarella A, Horbaczewska A, Anazodo A, Arvas A, Ramalho de Carvalho B, Sartorio C, Beerendonk CCM, Diaz-Garcia C, Suh CS, Melo C, Andersen CY, Motta E, Greenblatt EM, Van Moer E, Zand E, Reis FM, Sánchez F, Terrado G, Rodrigues JK, Marcos de Meneses E Silva J, Smitz J, Medrano J, Lee JR, Winkler-Crepaz K, Smith K, Ferreira Melo E Silva LH, Wildt L, Salama M, Del Mar Andrés M, Bourlon MT, Vega M, Chehin MB, De Vos M, Khrouf M, Suzuki N, Azmy O, Fontoura P, Campos-Junior PHA, Mallmann P, Azambuja R, Marinho RM, Anderson RA, Jach R, Antunes RA, Mitchell R, Fathi R, Adiga SK, Takae S, Kim SH, Romero S, Grieco SC, Shaulov T, Furui T, Almeida-Santos T, Nelen W, Jayasinghe Y, Sugishita Y, Woodruff TK.

J Glob Oncol. 2018 Sep;4:1-7. doi: 10.1200/JGO.2017.009944. Epub 2017 Jun 30.

6.

Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe.

Rashedi AS, de Roo SF, Ataman LM, Edmonds ME, Silva AA, Scarella A, Horbaczewska A, Anazodo A, Arvas A, Ramalho de Carvalho B, Sartorio C, Beerendonk CCM, Diaz-Garcia C, Suh CS, Melo C, Yding Andersen C, Motta E, Greenblatt EM, Van Moer E, Zand E, Reis FM, Sánchez F, Terrado G, Rodrigues JK, de Meneses E Silva JM, Smitz J, Medrano J, Lee JR, Winkler-Crepaz K, Smith K, Ferreira Melo E Silva LH, Wildt L, Salama M, Del Mar Andrés M, Bourlon MT, Vega M, Chehin MB, De Vos M, Khrouf M, Suzuki N, Azmy O, Fontoura P, Campos-Junior PHA, Mallmann P, Azambuja R, Marinho RM, Anderson RA, Jach R, Antunes RA, Mitchell R, Fathi R, Adiga SK, Takae S, Kim SH, Romero S, Chedid Grieco S, Shaulov T, Furui T, Almeida-Santos T, Nelen W, Jayasinghe Y, Sugishita Y, Woodruff TK.

J Glob Oncol. 2018 Sep;4:1-16. doi: 10.1200/JGO.2016.008144. Epub 2017 Jun 28.

7.

A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.

Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators.

Alzheimers Res Ther. 2017 Dec 8;9(1):95. doi: 10.1186/s13195-017-0318-y. Erratum in: Alzheimers Res Ther. 2018 Sep 27;10(1):99.

8.

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.

Youssef EA, Berry-Kravis E, Czech C, Hagerman RJ, Hessl D, Wong CY, Rabbia M, Deptula D, John A, Kinch R, Drewitt P, Lindemann L, Marcinowski M, Langland R, Horn C, Fontoura P, Santarelli L, Quiroz JA; FragXis Study Group.

Neuropsychopharmacology. 2018 Feb;43(3):503-512. doi: 10.1038/npp.2017.177. Epub 2017 Aug 17.

9.

A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder.

Umbricht D, Del Valle Rubido M, Hollander E, McCracken JT, Shic F, Scahill L, Noeldeke J, Boak L, Khwaja O, Squassante L, Grundschober C, Kletzl H, Fontoura P.

Neuropsychopharmacology. 2017 Aug;42(9):1924. doi: 10.1038/npp.2017.92.

10.

Three new <i>Batillipes</i> species (Arthrotardigrada: Batillipedidae) from the Brazilian coast.

Santos E, Rocha CMCD, Gomes EJ, Fontoura P.

Zootaxa. 2017 Mar 16;4243(3):483-502. doi: 10.11646/zootaxa.4243.3.4.

PMID:
28610140
11.

Two new species of Tardigrada (Eutardigrada: Ramazzottiidae, Macrobiotidae) from the supralittoral zone of the Atlantic Iberian Peninsula rocky shores.

Fontoura P, Rubal M, Veiga P.

Zootaxa. 2017 May 10;4263(3):450-466. doi: 10.11646/zootaxa.4263.3.2.

PMID:
28609855
12.

Sembragiline in Moderate Alzheimer's Disease: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Trial (MAyflOwer RoAD).

Nave S, Doody RS, Boada M, Grimmer T, Savola JM, Delmar P, Pauly-Evers M, Nikolcheva T, Czech C, Borroni E, Ricci B, Dukart J, Mannino M, Carey T, Moran E, Gilaberte I, Muelhardt NM, Gerlach I, Santarelli L, Ostrowitzki S, Fontoura P.

J Alzheimers Dis. 2017;58(4):1217-1228. doi: 10.3233/JAD-161309.

13.

Safety and efficacy of olesoxime in patients with type 2 or non-ambulatory type 3 spinal muscular atrophy: a randomised, double-blind, placebo-controlled phase 2 trial.

Bertini E, Dessaud E, Mercuri E, Muntoni F, Kirschner J, Reid C, Lusakowska A, Comi GP, Cuisset JM, Abitbol JL, Scherrer B, Ducray PS, Buchbjerg J, Vianna E, van der Pol WL, Vuillerot C, Blaettler T, Fontoura P; Olesoxime SMA Phase 2 Study Investigators.

Lancet Neurol. 2017 Jul;16(7):513-522. doi: 10.1016/S1474-4422(17)30085-6. Epub 2017 Apr 28. Erratum in: Lancet Neurol. 2017 Aug;16(8):584.

14.

Leptin Improves Sperm Cryopreservation via Antioxidant Defense.

Fontoura P, Mello MD, Gallo-Sá P, Erthal-Martins MC, Cardoso MC, Ramos C.

J Reprod Infertil. 2017 Jan-Mar;18(1):172-178.

15.

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.

Montalban X, Hauser SL, Kappos L, Arnold DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Rammohan KW, Selmaj K, Traboulsee A, Sauter A, Masterman D, Fontoura P, Belachew S, Garren H, Mairon N, Chin P, Wolinsky JS; ORATORIO Clinical Investigators.

N Engl J Med. 2017 Jan 19;376(3):209-220. doi: 10.1056/NEJMoa1606468. Epub 2016 Dec 21.

16.

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.

Hauser SL, Bar-Or A, Comi G, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Montalban X, Rammohan KW, Selmaj K, Traboulsee A, Wolinsky JS, Arnold DL, Klingelschmitt G, Masterman D, Fontoura P, Belachew S, Chin P, Mairon N, Garren H, Kappos L; OPERA I and OPERA II Clinical Investigators.

N Engl J Med. 2017 Jan 19;376(3):221-234. doi: 10.1056/NEJMoa1601277. Epub 2016 Dec 21.

17.

Reactive Case Detection for Plasmodium vivax Malaria Elimination in Rural Amazonia.

Fontoura PS, Finco BF, Lima NF, de Carvalho JF Jr, Vinetz JM, Castro MC, Ferreira MU.

PLoS Negl Trop Dis. 2016 Dec 12;10(12):e0005221. doi: 10.1371/journal.pntd.0005221. eCollection 2016 Dec.

18.

A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder.

Umbricht D, Del Valle Rubido M, Hollander E, McCracken JT, Shic F, Scahill L, Noeldeke J, Boak L, Khwaja O, Squassante L, Grundschober C, Kletzl H, Fontoura P.

Neuropsychopharmacology. 2017 Aug;42(9):1914-1923. doi: 10.1038/npp.2016.232. Epub 2016 Oct 6. Erratum in: Neuropsychopharmacology. 2017 Aug;42(9):1924.

19.

Efficacy and Safety of Basimglurant as Adjunctive Therapy for Major Depression: A Randomized Clinical Trial.

Quiroz JA, Tamburri P, Deptula D, Banken L, Beyer U, Rabbia M, Parkar N, Fontoura P, Santarelli L.

JAMA Psychiatry. 2016 Jul 1;73(7):675-84. doi: 10.1001/jamapsychiatry.2016.0838.

PMID:
27304433
20.

New records of marine tardigrades from Moorea, French Polynesia, with the description of Styraconyx turbinarium sp. nov. (Arthrotardigrada, Halechiniscidae).

Bartels PJ, Fontoura P, Nelson DR.

Zootaxa. 2015 May 5;3955(3):389-402. doi: 10.11646/zootaxa.3955.3.6.

PMID:
25947860
21.

The effects of liraglutide on male fertility: a case report.

Fontoura P, Cardoso MC, Erthal-Martins MC, Werneck C, Sartorio C, Ramos CF.

Reprod Biomed Online. 2014 Nov;29(5):644-6. doi: 10.1016/j.rbmo.2014.07.009. Epub 2014 Jul 29.

PMID:
25246122
22.

Epidemiology of disappearing Plasmodium vivax malaria: a case study in rural Amazonia.

Barbosa S, Gozze AB, Lima NF, Batista CL, Bastos Mda S, Nicolete VC, Fontoura PS, Gonçalves RM, Viana SA, Menezes MJ, Scopel KK, Cavasini CE, Malafronte Rdos S, da Silva-Nunes M, Vinetz JM, Castro MC, Ferreira MU.

PLoS Negl Trop Dis. 2014 Aug 28;8(8):e3109. doi: 10.1371/journal.pntd.0003109. eCollection 2014 Aug.

23.

Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.

Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, Furia B, Risher N, Sheedy J, Kong R, Ma J, Turpoff A, Lee CS, Zhang X, Moon YC, Trifillis P, Welch EM, Colacino JM, Babiak J, Almstead NG, Peltz SW, Eng LA, Chen KS, Mull JL, Lynes MS, Rubin LL, Fontoura P, Santarelli L, Haehnke D, McCarthy KD, Schmucki R, Ebeling M, Sivaramakrishnan M, Ko CP, Paushkin SV, Ratni H, Gerlach I, Ghosh A, Metzger F.

Science. 2014 Aug 8;345(6197):688-93. doi: 10.1126/science.1250127.

24.

Epidemiology and control of child toxocariasis in the western Brazilian Amazon - a population-based study.

Oliart-Guzmán H, Delfino BM, Martins AC, Mantovani SA, Braña AM, Pereira TM, Branco FL, Ramalho AA, Campos RG, Fontoura PS, de Araujo TS, de Oliveira CS, Muniz PT, Rubinsky-Elefant G, Codeço CT, da Silva-Nunes M.

Am J Trop Med Hyg. 2014 Apr;90(4):670-81. doi: 10.4269/ajtmh.13-0506. Epub 2014 Feb 10.

25.

Drug discovery for autism spectrum disorder: challenges and opportunities.

Ghosh A, Michalon A, Lindemann L, Fontoura P, Santarelli L.

Nat Rev Drug Discov. 2013 Oct;12(10):777-90. doi: 10.1038/nrd4102. Review.

PMID:
24080699
26.
27.

Integrative taxonomy allows the identification of synonymous species and the erection of a new genus of Echiniscidae (Tardigrada, Heterotardigrada).

Vicente F, Fontoura P, Cesari M, Rebecchi L, Guidetti R, Serrano A, Bertolani R.

Zootaxa. 2013 Feb 14;3613:557-72. doi: 10.11646/zootaxa.3613.6.3.

PMID:
24698838
28.

Defective nitric oxide-cyclic guanosine monophosphate signaling in patients with bipolar disorder: a potential role for platelet dysfunction.

Fontoura PC, Pinto VL, Matsuura C, Resende Ade C, de Bem GF, Ferraz MR, Cheniaux E, Brunini TM, Mendes-Ribeiro AC.

Psychosom Med. 2012 Oct;74(8):873-7. doi: 10.1097/PSY.0b013e3182689460. Epub 2012 Sep 28.

PMID:
23023680
29.

Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects.

Sievers C, Meira M, Hoffmann F, Fontoura P, Kappos L, Lindberg RL.

Clin Immunol. 2012 Jul;144(1):70-9. doi: 10.1016/j.clim.2012.04.002. Epub 2012 May 2.

PMID:
22659298
30.

Prerequisites to launch neuroprotective trials in Parkinson's disease: an industry perspective.

Streffer JR, Grachev ID, Fitzer-Attas C, Gomez-Mancilla B, Boroojerdi B, Bronzova J, Ostrowitzki S, Victor SJ, Fontoura P, Alexander R.

Mov Disord. 2012 Apr 15;27(5):651-5. doi: 10.1002/mds.25017. Review.

PMID:
22508283
31.

Monoclonal antibody therapy in multiple sclerosis: Paradigm shifts and emerging challenges.

Fontoura P.

MAbs. 2010 Nov-Dec;2(6):670-81. doi: 10.4161/mabs.2.6.13270. Review.

32.

Multiple sclerosis therapies: molecular mechanisms and future.

Fontoura P, Garren H.

Results Probl Cell Differ. 2010;51:259-85. doi: 10.1007/400_2010_36. Review.

PMID:
20838962
33.

The 'Ajuda Paralyses': history of a neuropsychiatric debate in mid-19th-century Portugal.

Fontoura P.

Brain. 2010 Oct;133(10):3141-52. doi: 10.1093/brain/awq211. Epub 2010 Aug 18.

PMID:
20719878
34.

The Global Adherence Project (GAP): a multicenter observational study on adherence to disease-modifying therapies in patients with relapsing-remitting multiple sclerosis.

Devonshire V, Lapierre Y, Macdonell R, Ramo-Tello C, Patti F, Fontoura P, Suchet L, Hyde R, Balla I, Frohman EM, Kieseier BC; GAP Study Group.

Eur J Neurol. 2011 Jan;18(1):69-77. doi: 10.1111/j.1468-1331.2010.03110.x.

PMID:
20561039
35.

Roles of B lymphocytes in multiple sclerosis: diversifying beyond the antibody response.

Fontoura P.

Immunotherapy. 2009 Mar;1(2):181-5. doi: 10.2217/1750743X.1.2.181.

PMID:
20635939
36.

Video NeuroImage: symptomatic SUNCT syndrome cured after trigeminal neurovascular contact surgical decompression.

Guerreiro R, Casimiro M, Lopes D, Marques JP, Fontoura P.

Neurology. 2009 Feb 17;72(7):e37. doi: 10.1212/01.wnl.0000342483.46328.1a. No abstract available.

PMID:
19221289
37.

Neurological practice in the Centuriae of Amatus Lusitanus.

Fontoura P.

Brain. 2009 Feb;132(Pt 2):296-308. doi: 10.1093/brain/awn327. Epub 2009 Jan 19.

PMID:
19153148
38.

Hourglass brain.

Guerreiro RM, Fontoura P.

Neurology. 2008 Jul 8;71(2):149. doi: 10.1212/01.wnl.0000316809.62935.79. No abstract available.

PMID:
18606971
39.

Novel human pathological mutations. Gene symbol: NOTCH3. Disease: cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL).

Ferreira S, Fontoura P, Guerreiro R, Oliveira JP.

Hum Genet. 2007 Jun;121(5):649-50. No abstract available.

PMID:
17879447
40.

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation.

Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP.

J Clin Invest. 2007 Feb;117(2):438-47. Epub 2007 Jan 25.

41.

Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review.

Langer-Gould A, Popat RA, Huang SM, Cobb K, Fontoura P, Gould MK, Nelson LM.

Arch Neurol. 2006 Dec;63(12):1686-91. Review.

PMID:
17172607
42.

[Multiple brain abscesses of a mycotic origin in an immunocompetent individual].

Guerreiro R, Rodrigues M, Fontoura P, Pinto-Marques J.

Rev Neurol. 2006 Nov 1-15;43(9):567-8. Spanish. No abstract available.

43.

Emerging therapeutic targets in multiple sclerosis.

Fontoura P, Steinman L, Miller A.

Curr Opin Neurol. 2006 Jun;19(3):260-6. Review.

PMID:
16702832
44.

Nogo in multiple sclerosis: growing roles of a growth inhibitor.

Fontoura P, Steinman L.

J Neurol Sci. 2006 Jun 15;245(1-2):201-10. Epub 2006 May 6. Review.

PMID:
16682057
45.

Antigen-specific therapies in multiple sclerosis: going beyond proteins and peptides.

Fontoura P, Garren H, Steinman L.

Int Rev Immunol. 2005 Sep-Dec;24(5-6):415-46. Review.

PMID:
16318989
46.

[Balint's syndrome due to sequential bilateral haematomas].

Fontoura P, Guerreiro R, Pinto-Marques J.

Rev Neurol. 2005 Nov 16-30;41(10):622-3. Spanish. No abstract available.

47.

Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite.

Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L.

Science. 2005 Nov 4;310(5749):850-5. Erratum in: Science. 2006 Feb 17;311(5763):954.

48.

A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease.

Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, Robinson WH, Steinman L.

J Immunol. 2005 Nov 1;175(9):6226-34.

49.
50.

Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis.

Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L.

J Immunol. 2004 Dec 1;173(11):6981-92.

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