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Machine learning can identify newly diagnosed patients with CLL at high risk of infection.

Agius R, Brieghel C, Andersen MA, Pearson AT, Ledergerber B, Cozzi-Lepri A, Louzoun Y, Andersen CL, Bergstedt J, von Stemann JH, Jørgensen M, Tang ME, Fontes M, Bahlo J, Herling CD, Hallek M, Lundgren J, MacPherson CR, Larsen J, Niemann CU.

Nat Commun. 2020 Jan 17;11(1):363. doi: 10.1038/s41467-019-14225-8.


Renal sympathetic denervation for resistant hypertension: where do we stand after more than a decade.

Fontes MAP, Marzano LAS, Silva CC, Silva ACSE.

J Bras Nefrol. 2020 Jan 10. pii: S0101-28002020005001101. doi: 10.1590/2175-8239-JBN-2018-0213. [Epub ahead of print] English, Portuguese.


Heavy metals in iron ore tailings and floodplain soils affected by the Samarco dam collapse in Brazil.

Davila RB, Fontes MPF, Pacheco AA, Ferreira MDS.

Sci Total Environ. 2019 Dec 16;709:136151. doi: 10.1016/j.scitotenv.2019.136151. [Epub ahead of print]


Risk assessment of trace elements pollution of Manaus urban rivers.

Ferreira MDS, Fontes MPF, Pacheco AA, Lima HN, Santos JZL.

Sci Total Environ. 2019 Dec 10;709:134471. doi: 10.1016/j.scitotenv.2019.134471. [Epub ahead of print]


Genomics of lethal prostate cancer at diagnosis and castration-resistance.

Mateo J, Seed G, Bertan C, Rescigno P, Dolling D, Figueiredo I, Miranda S, Nava Rodrigues D, Gurel B, Clarke M, Atkin M, Chandler R, Messina C, Sumanasuriya S, Bianchini D, Barrero M, Petremolo A, Zafeiriou Z, Fontes MS, Perez-Lopez R, Tunariu N, Fulton BA, Jones R, McGovern UB, Ralph C, Varughese M, Parikh O, Jain S, Elliott T, Sandhu S, Porta N, Hall E, Yuan W, Carreira S, de Bono JS.

J Clin Invest. 2019 Dec 24. pii: 132031. doi: 10.1172/JCI132031. [Epub ahead of print]


Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920).

Salvador GHM, Gomes AAS, Bryan-Quirós W, Fernández J, Lewin MR, Gutiérrez JM, Lomonte B, Fontes MRM.

Sci Rep. 2019 Nov 20;9(1):17203. doi: 10.1038/s41598-019-53755-5.


A bacterial light response reveals an orphan desaturase for human plasmalogen synthesis.

Gallego-García A, Monera-Girona AJ, Pajares-Martínez E, Bastida-Martínez E, Pérez-Castaño R, Iniesta AA, Fontes M, Padmanabhan S, Elías-Arnanz M.

Science. 2019 Oct 4;366(6461):128-132. doi: 10.1126/science.aay1436.


Seasonal monitoring of cocaine and benzoylecgonine in a subtropical coastal zone (Santos Bay, Brazil).

Fontes MK, de Campos BG, Cortez FS, Pusceddu FH, Moreno BB, Maranho LA, Lebre DT, Guimarães LL, Pereira CDS.

Mar Pollut Bull. 2019 Dec;149:110545. doi: 10.1016/j.marpolbul.2019.110545. Epub 2019 Sep 5.


Syndromic Oral Clefts: Challenges of Genetic Assessment in Brazil and Suggestions to Improve Health Policies.

Gil-da-Silva-Lopes VL, Fontes MIB, Dos Santos AP, Appenzeller S, Fett-Conte AC, Francisquetti MCC, Monlleó IL.

Public Health Genomics. 2019;22(1-2):69-76. doi: 10.1159/000501973. Epub 2019 Aug 27.


DISSEQT-DIStribution-based modeling of SEQuence space Time dynamics.

Henningsson R, Moratorio G, Bordería AV, Vignuzzi M, Fontes M.

Virus Evol. 2019 Aug 5;5(2):vez028. doi: 10.1093/ve/vez028. eCollection 2019 Jul. Erratum in: Virus Evol. 2019 Nov 19;5(2):vez052.


Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver.

Fonseca RC, Bassi GS, Brito CC, Rosa LB, David BA, Araújo AM, Nóbrega N, Diniz AB, Jesus ICG, Barcelos LS, Fontes MAP, Bonaventura D, Kanashiro A, Cunha TM, Guatimosim S, Cardoso VN, Fernandes SOA, Menezes GB, de Lartigue G, Oliveira AG.

Brain Behav Immun. 2019 Oct;81:444-454. doi: 10.1016/j.bbi.2019.06.041. Epub 2019 Jul 2.


The influence of thermal comfort conditions on user's exposure time in open spaces.

Faustini FB, de Faria JRG, Fontes MSGC.

Int J Biometeorol. 2019 Jun 27. doi: 10.1007/s00484-019-01749-3. [Epub ahead of print]


Vulnerability of seagrass blue carbon to microbial attack following exposure to warming and oxygen.

Macreadie PI, Atwood TB, Seymour JR, Fontes MLS, Sanderman J, Nielsen DA, Connolly RM.

Sci Total Environ. 2019 Oct 10;686:264-275. doi: 10.1016/j.scitotenv.2019.05.462. Epub 2019 Jun 2.


Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.

Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, Canton T, Consiglio CR, Albert ML, Fontes M, Duffy D, Ingersoll MA.

JCI Insight. 2019 May 30;5. pii: 122998. doi: 10.1172/jci.insight.122998.


Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation.

Reina J, Zhou L, Fontes MRM, Panté N, Cella N.

FEBS Open Bio. 2019 Jul;9(7):1174-1183. doi: 10.1002/2211-5463.12626. Epub 2019 May 29.


Effect of maternal feed restriction in dairy goats at different stages of gestation on skeletal muscle development and energy metabolism of kids at the time of births.

Costa TC, Moura FH, Souza RO, Lopes MM, Fontes MMS, Serão NVL, Sanglard LP, Du M, Gionbelli MP, Duarte MS.

Anim Reprod Sci. 2019 Jul;206:46-59. doi: 10.1016/j.anireprosci.2019.05.006. Epub 2019 May 11.


Cardiovascular reactivity to emotional stress: The hidden challenge for pets in the urbanized environment.

Cunha Silva C, Fontes MAP.

Physiol Behav. 2019 Aug 1;207:151-158. doi: 10.1016/j.physbeh.2019.05.014. Epub 2019 May 14. Review.


Electrical impedance tomography monitoring during spontaneous breathing trial: Physiological description and potential clinical utility.

Lima JNG, Fontes MS, Szmuszkowicz T, Isola AM, Maciel AT.

Acta Anaesthesiol Scand. 2019 Sep;63(8):1019-1027. doi: 10.1111/aas.13383. Epub 2019 May 7.


Exercise training restores the myogenic response in skeletal muscle resistance arteries and corrects peripheral edema in rats with heart failure.

Paula SM, Couto GK, Fontes MT, Costa SK, Negrão CE, Mill JG, Rossoni LV.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H87-H96. doi: 10.1152/ajpheart.00042.2019. Epub 2019 May 3.


Marine contamination and cytogenotoxic effects of fluoxetine in the tropical brown mussel Perna perna.

Cortez FS, Souza LDS, Guimarães LL, Pusceddu FH, Maranho LA, Fontes MK, Moreno BB, Nobre CR, Abessa DMS, Cesar A, Pereira CDS.

Mar Pollut Bull. 2019 Apr;141:366-372. doi: 10.1016/j.marpolbul.2019.02.065. Epub 2019 Mar 6.


TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut.

Wang H, Kwon YH, Dewan V, Vahedi F, Syed S, Fontes ME, Ashkar AA, Surette MG, Khan WI.

J Immunol. 2019 May 15;202(10):3041-3052. doi: 10.4049/jimmunol.1801034. Epub 2019 Apr 5.


Siri – jeg har det ikke så godt. Kan du hjælpe mig?

Fontes M.

Ugeskr Laeger. 2019 Apr 1;181(7A). pii: V70142. Danish. No abstract available.


Dual cellular localization of the Leishmania amazonensis Rbp38 (LaRbp38) explains its affinity for telomeric and mitochondrial DNA.

Fernandes CAH, Perez AM, Barros AC, Dreyer TR, da Silva MS, Morea EGO, Fontes MRM, Cano MIN.

Biochimie. 2019 Jul;162:15-25. doi: 10.1016/j.biochi.2019.03.017. Epub 2019 Mar 28.


Glymphatic System Function in Relation to Anesthesia and Sleep States.

Benveniste H, Heerdt PM, Fontes M, Rothman DL, Volkow ND.

Anesth Analg. 2019 Apr;128(4):747-758. doi: 10.1213/ANE.0000000000004069. Review.


Simplex-Centroid mixture design applied to arsenic (V) removal from waters using synthetic minerals.

Dias AC, Fontes MPF, Reis C, Bellato CR, Fendorf S.

J Environ Manage. 2019 May 15;238:92-101. doi: 10.1016/j.jenvman.2019.02.099. Epub 2019 Mar 5.


Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis.

Kwon YH, Wang H, Denou E, Ghia JE, Rossi L, Fontes ME, Bernier SP, Shajib MS, Banskota S, Collins SM, Surette MG, Khan WI.

Cell Mol Gastroenterol Hepatol. 2019;7(4):709-728. doi: 10.1016/j.jcmgh.2019.01.004. Epub 2019 Feb 1.


Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches.

Salvador GHM, Cardoso FF, Gomes AA, Cavalcante WLG, Gallacci M, Fontes MRM.

Sci Rep. 2019 Jan 24;9(1):510. doi: 10.1038/s41598-018-36839-6.


Ex situ catalytic biomass pyrolysis using mesoporous Ti-MCM-41.

Fontes MDSB, Melo DMA, Fontes LAO, Braga RM, Costa CC, Martinelli AE.

Environ Sci Pollut Res Int. 2019 Feb;26(6):5983-5989. doi: 10.1007/s11356-018-4003-x. Epub 2019 Jan 6.


Sodium-glucose cotransporter-2 inhibitors: an overview and perioperative implications.

Bardia A, Wai M, Fontes ML.

Curr Opin Anaesthesiol. 2019 Feb;32(1):80-85. doi: 10.1097/ACO.0000000000000674. Review.


Charcot Marie Tooth Disease. A Single Disorder?

Fontés M.

Int J Mol Sci. 2018 Nov 29;19(12). pii: E3807. doi: 10.3390/ijms19123807.


EpCAMhigh and EpCAMlow circulating tumor cells in metastatic prostate and breast cancer patients.

de Wit S, Manicone M, Rossi E, Lampignano R, Yang L, Zill B, Rengel-Puertas A, Ouhlen M, Crespo M, Berghuis AMS, Andree KC, Vidotto R, Trapp EK, Tzschaschel M, Colomba E, Fowler G, Flohr P, Rescigno P, Fontes MS, Zamarchi R, Fehm T, Neubauer H, Rack B, Alunni-Fabbroni M, Farace F, De Bono J, IJzerman MJ, Terstappen LWMM.

Oncotarget. 2018 Nov 2;9(86):35705-35716. doi: 10.18632/oncotarget.26298. eCollection 2018 Nov 2.


Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.

Rodrigues DN, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Mendes LST, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS.

J Clin Invest. 2018 Nov 1;128(11):5185. doi: 10.1172/JCI125184. Epub 2018 Nov 1. No abstract available.


Simultaneous identification of the wood types in aged cachaças and their adulterations with wood extracts using digital images and SPA-LDA.

de Sousa Fernandes DD, de Almeida VE, Fontes MM, de Araújo MCU, Véras G, Diniz PHGD.

Food Chem. 2019 Feb 1;273:77-84. doi: 10.1016/j.foodchem.2018.02.035. Epub 2018 Feb 8.


Smoking habit modulates peri-implant microbiome: A case-control study.

Pimentel SP, Fontes M, Ribeiro FV, Corrêa MG, Nishii D, Cirano FR, Casati MZ, Casarin RCV.

J Periodontal Res. 2018 Dec;53(6):983-991. doi: 10.1111/jre.12597. Epub 2018 Sep 26.


Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins.

Cardoso FF, Borges RJ, Dreyer TR, Salvador GHM, Cavalcante WLG, Pai MD, Gallacci M, Fontes MRM.

Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2728-2737. doi: 10.1016/j.bbagen.2018.08.002. Epub 2018 Aug 4.


Impact of malocclusion on oral health-related quality of life among schoolchildren.

Guimarães SPA, Jorge KO, Fontes MJF, Ramos-Jorge ML, Araújo CTP, Ferreira EF, Melgaço CA, Zarzar PM.

Braz Oral Res. 2018;32:e95. doi: 10.1590/1807-3107bor-2018.vol32.0095. Epub 2018 Sep 17.


Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

Clave E, Araujo IL, Alanio C, Patin E, Bergstedt J, Urrutia A, Lopez-Lastra S, Li Y, Charbit B, MacPherson CR, Hasan M, Melo-Lima BL, Douay C, Saut N, Germain M, Trégouët DA, Morange PE, Fontes M, Duffy D, Di Santo JP, Quintana-Murci L, Albert ML, Toubert A; Milieu Intérieur Consortium.

Sci Transl Med. 2018 Sep 5;10(457). pii: eaao2966. doi: 10.1126/scitranslmed.aao2966.


Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.

Nava Rodrigues D, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Teixeira Mendes LS, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS.

J Clin Invest. 2018 Oct 1;128(10):4441-4453. doi: 10.1172/JCI121924. Epub 2018 Sep 4. Erratum in: J Clin Invest. 2018 Nov 1;128(11):5185.


In Vivo genotoxicity of a commercial C.I. Disperse Red 1 dye.

Fernandes FH, Botasso-Nasciutti MO, Svio ALV, Souza LDCM, Fernandes-Cal JR, Cardoso FF, Fontes MRM, Albuquerque AF, Munari CC, Kummrow F, Umbuzeiro GA, Salvadori DMF.

Environ Mol Mutagen. 2018 Dec;59(9):822-828. doi: 10.1002/em.22226. Epub 2018 Aug 27.


Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis.

Lambros MB, Seed G, Sumanasuriya S, Gil V, Crespo M, Fontes M, Chandler R, Mehra N, Fowler G, Ebbs B, Flohr P, Miranda S, Yuan W, Mackay A, Ferreira A, Pereira R, Bertan C, Figueiredo I, Riisnaes R, Rodrigues DN, Sharp A, Goodall J, Boysen G, Carreira S, Bianchini D, Rescigno P, Zafeiriou Z, Hunt J, Moloney D, Hamilton L, Neves RP, Swennenhuis J, Andree K, Stoecklein NH, Terstappen LWMM, de Bono JS.

Clin Cancer Res. 2018 Nov 15;24(22):5635-5644. doi: 10.1158/1078-0432.CCR-18-0862. Epub 2018 Aug 9.


A Glutamatergic Hypothalamomedullary Circuit Mediates Thermogenesis, but Not Heat Conservation, during Stress-Induced Hyperthermia.

Machado NLS, Abbott SBG, Resch JM, Zhu L, Arrigoni E, Lowell BB, Fuller PM, Fontes MAP, Saper CB.

Curr Biol. 2018 Jul 23;28(14):2291-2301.e5. doi: 10.1016/j.cub.2018.05.064. Epub 2018 Jul 12.


SMSSVD: SubMatrix Selection Singular Value Decomposition.

Henningsson R, Fontes M.

Bioinformatics. 2019 Feb 1;35(3):478-486. doi: 10.1093/bioinformatics/bty566.


Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.

Salvador GHM, Dreyer TR, Gomes AAS, Cavalcante WLG, Dos Santos JI, Gandin CA, de Oliveira Neto M, Gallacci M, Fontes MRM.

Sci Rep. 2018 Jul 9;8(1):10317. doi: 10.1038/s41598-018-28584-7.


Involvement of GABAergic and Adrenergic Neurotransmissions on Paraventricular Nucleus of Hypothalamus in the Control of Cardiac Function.

Mendonça MM, Santana JS, da Cruz KR, Ianzer D, Ghedini PC, Nalivaiko E, Fontes MAP, Ferreira RN, Pedrino GR, Colugnati DB, Xavier CH.

Front Physiol. 2018 Jun 4;9:670. doi: 10.3389/fphys.2018.00670. eCollection 2018.


Multifactorial control of the expression of a CRISPR-Cas system by an extracytoplasmic function σ/anti-σ pair and a global regulatory complex.

Bernal-Bernal D, Abellón-Ruiz J, Iniesta AA, Pajares-Martínez E, Bastida-Martínez E, Fontes M, Padmanabhan S, Elías-Arnanz M.

Nucleic Acids Res. 2018 Jul 27;46(13):6726-6745. doi: 10.1093/nar/gky475.


Inflammation-related differences in mucosa-associated microbiota and intestinal barrier function in colonic Crohn's disease.

Libertucci J, Dutta U, Kaur S, Jury J, Rossi L, Fontes ME, Shajib MS, Khan WI, Surette MG, Verdu EF, Armstrong D.

Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G420-G431. doi: 10.1152/ajpgi.00411.2017. Epub 2018 May 31.


Publisher Correction: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Di Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium.

Nat Immunol. 2018 Jun;19(6):645. doi: 10.1038/s41590-018-0105-3.


Stating asymmetry in neural pathways: methodological trends in autonomic neuroscience.

Xavier CH, Mendonça MM, Marins FR, da Silva ES, Ianzer D, Colugnati DB, Pedrino GR, Fontes MAP.

Int J Neurosci. 2018 Nov;128(11):1078-1085. doi: 10.1080/00207454.2018.1473396. Epub 2018 May 22. Review.


Circulating tumor cells, tumor-derived extracellular vesicles and plasma cytokeratins in castration-resistant prostate cancer patients.

Nanou A, Coumans FAW, van Dalum G, Zeune LL, Dolling D, Onstenk W, Crespo M, Fontes MS, Rescigno P, Fowler G, Flohr P, Brune C, Sleijfer S, de Bono JS, Terstappen LWMM.

Oncotarget. 2018 Apr 10;9(27):19283-19293. doi: 10.18632/oncotarget.25019. eCollection 2018 Apr 10.


Speciation, bioaccessibility and potential risk of chromium in Amazon forest soils.

Moreira LJD, da Silva EB, Fontes MPF, Liu X, Ma LQ.

Environ Pollut. 2018 Aug;239:384-391. doi: 10.1016/j.envpol.2018.04.025. Epub 2018 Apr 16.


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