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Items: 1 to 50 of 91

1.

Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension.

Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB.

J Am Heart Assoc. 2019 Aug 6;8(15):e013111. doi: 10.1161/JAHA.119.013111. Epub 2019 Jul 24.

2.

Protective role of B cells in sterile particulate-induced lung injury.

Atif SM, Mack DG, McKee AS, Rangel-Moreno J, Martin AK, Getahun A, Maier LA, Cambier JC, Tuder R, Fontenot AP.

JCI Insight. 2019 May 16;5. pii: 125494. doi: 10.1172/jci.insight.125494.

3.

Upregulation of Chitinase 1 in Alveolar Macrophages of HIV-Infected Smokers.

Logue EC, Neff CP, Mack DG, Martin AK, Fiorillo S, Lavelle J, Vandivier RW, Campbell TB, Palmer BE, Fontenot AP.

J Immunol. 2019 Mar 1;202(5):1363-1372. doi: 10.4049/jimmunol.1801105. Epub 2019 Jan 21.

PMID:
30665939
4.

An exploration of Prevotella-rich microbiomes in HIV and men who have sex with men.

Armstrong AJS, Shaffer M, Nusbacher NM, Griesmer C, Fiorillo S, Schneider JM, Preston Neff C, Li SX, Fontenot AP, Campbell T, Palmer BE, Lozupone CA.

Microbiome. 2018 Nov 5;6(1):198. doi: 10.1186/s40168-018-0580-7.

5.

TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization.

Wade MF, Collins MK, Richards D, Mack DG, Martin AK, Dinarello CA, Fontenot AP, McKee AS.

J Immunol. 2018 Oct 15;201(8):2232-2243. doi: 10.4049/jimmunol.1800303. Epub 2018 Sep 5.

6.

Immunologic Effects of Beryllium Exposure.

Fontenot AP.

Ann Am Thorac Soc. 2018 Apr;15(Suppl 2):S81-S85. doi: 10.1513/AnnalsATS.201707-573MG.

7.

Genetic, Immunologic, and Environmental Basis of Sarcoidosis.

Moller DR, Rybicki BA, Hamzeh NY, Montgomery CG, Chen ES, Drake W, Fontenot AP.

Ann Am Thorac Soc. 2017 Dec;14(Supplement_6):S429-S436. doi: 10.1513/AnnalsATS.201707-565OT. Review.

8.

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome.

Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP.

J Immunol. 2017 Oct 1;199(7):2279-2290. doi: 10.4049/jimmunol.1700570. Epub 2017 Aug 21.

9.

Mechanisms Underlying HIV-Associated Noninfectious Lung Disease.

Presti RM, Flores SC, Palmer BE, Atkinson JJ, Lesko CR, Lau B, Fontenot AP, Roman J, McDyer JF, Twigg HL 3rd.

Chest. 2017 Nov;152(5):1053-1060. doi: 10.1016/j.chest.2017.04.154. Epub 2017 Apr 17. Review.

10.

Interplay of innate and adaptive immunity in metal-induced hypersensitivity.

McKee AS, Fontenot AP.

Curr Opin Immunol. 2016 Oct;42:25-30. doi: 10.1016/j.coi.2016.05.001. Epub 2016 May 23. Review.

11.

Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.

Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. doi: 10.1073/pnas.1606994113. Epub 2016 Jun 15.

12.

The Impact of Antiretroviral Therapy on Lung Immunology.

Cribbs SK, Fontenot AP.

Semin Respir Crit Care Med. 2016 Apr;37(2):157-65. doi: 10.1055/s-0036-1572554. Epub 2016 Mar 14. Review.

PMID:
26974295
13.

Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation.

Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS.

J Immunol. 2016 Jan 1;196(1):22-7. doi: 10.4049/jimmunol.1502011. Review.

14.

Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals.

Beck JM, Schloss PD, Venkataraman A, Twigg H 3rd, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB; Lung HIV Microbiome Project.

Am J Respir Crit Care Med. 2015 Dec 1;192(11):1335-44. doi: 10.1164/rccm.201501-0128OC.

15.

Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice.

Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP.

Mucosal Immunol. 2016 Jan;9(1):218-28. doi: 10.1038/mi.2015.54. Epub 2015 Jul 1.

16.

MyD88 dependence of beryllium-induced dendritic cell trafficking and CD4⁺ T-cell priming.

McKee AS, Mack DG, Crawford F, Fontenot AP.

Mucosal Immunol. 2015 Nov;8(6):1237-47. doi: 10.1038/mi.2015.14. Epub 2015 Mar 11.

17.

Lymphocytic alveolitis is associated with the accumulation of functionally impaired HIV-specific T cells in the lung of antiretroviral therapy-naive subjects.

Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):464-73. doi: 10.1164/rccm.201408-1521OC.

18.

An official American Thoracic Society statement: diagnosis and management of beryllium sensitivity and chronic beryllium disease.

Balmes JR, Abraham JL, Dweik RA, Fireman E, Fontenot AP, Maier LA, Muller-Quernheim J, Ostiguy G, Pepper LD, Saltini C, Schuler CR, Takaro TK, Wambach PF; ATS Ad Hoc Committee on Beryllium Sensitivity and Chronic Beryllium Disease.

Am J Respir Crit Care Med. 2014 Nov 15;190(10):e34-59. doi: 10.1164/rccm.201409-1722ST. Review.

PMID:
25398119
19.

HIV-induced alteration in gut microbiota: driving factors, consequences, and effects of antiretroviral therapy.

Lozupone CA, Rhodes ME, Neff CP, Fontenot AP, Campbell TB, Palmer BE.

Gut Microbes. 2014 Jul 1;5(4):562-70. doi: 10.4161/gmic.32132. Epub 2014 Jul 31. Review.

PMID:
25078714
20.

Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.

Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW.

Cell. 2014 Jul 3;158(1):132-42. doi: 10.1016/j.cell.2014.04.048.

21.

Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease.

Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8553-8. doi: 10.1073/pnas.1408048111. Epub 2014 May 27.

22.

Identification of multiple public TCR repertoires in chronic beryllium disease.

Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP.

J Immunol. 2014 May 15;192(10):4571-80. doi: 10.4049/jimmunol.1400007. Epub 2014 Apr 9.

23.

Use of bronchoalveolar lavage to assess the respiratory microbiome: signal in the noise.

Twigg HL 3rd, Morris A, Ghedin E, Curtis JL, Huffnagle GB, Crothers K, Campbell TB, Flores SC, Fontenot AP, Beck JM, Huang L, Lynch S, Knox KS, Weinstock G; Lung HIV Microbiome Project.

Lancet Respir Med. 2013 Jul;1(5):354-6. doi: 10.1016/S2213-2600(13)70117-6. Epub 2013 Jul 8. No abstract available.

PMID:
24429191
24.

Allergy and hypersensitivity.

Fontenot AP, Peebles RS Jr.

Curr Opin Immunol. 2013 Dec;25(6):736-7. doi: 10.1016/j.coi.2013.10.007. Epub 2013 Oct 29. No abstract available.

PMID:
24183163
25.

Alterations in the gut microbiota associated with HIV-1 infection.

Lozupone CA, Li M, Campbell TB, Flores SC, Linderman D, Gebert MJ, Knight R, Fontenot AP, Palmer BE.

Cell Host Microbe. 2013 Sep 11;14(3):329-39. doi: 10.1016/j.chom.2013.08.006.

26.

T cell recognition of beryllium.

Dai S, Falta MT, Bowerman NA, McKee AS, Fontenot AP.

Curr Opin Immunol. 2013 Dec;25(6):775-80. doi: 10.1016/j.coi.2013.07.012. Epub 2013 Aug 23. Review.

27.

Impaired function of CTLA-4 in the lungs of patients with chronic beryllium disease contributes to persistent inflammation.

Chain JL, Martin AK, Mack DG, Maier LA, Palmer BE, Fontenot AP.

J Immunol. 2013 Aug 15;191(4):1648-56. doi: 10.4049/jimmunol.1300282. Epub 2013 Jul 12.

28.

Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease.

Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP.

J Exp Med. 2013 Jul 1;210(7):1403-18.

29.

Comparison of the respiratory microbiome in healthy nonsmokers and smokers.

Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, Flores SC, Fontenot AP, Ghedin E, Huang L, Jablonski K, Kleerup E, Lynch SV, Sodergren E, Twigg H, Young VB, Bassis CM, Venkataraman A, Schmidt TM, Weinstock GM; Lung HIV Microbiome Project.

Am J Respir Crit Care Med. 2013 May 15;187(10):1067-75. doi: 10.1164/rccm.201210-1913OC.

30.

Widespread colonization of the lung by Tropheryma whipplei in HIV infection.

Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP; Lung HIV Microbiome Project.

Am J Respir Crit Care Med. 2013 May 15;187(10):1110-7. doi: 10.1164/rccm.201211-2145OC.

31.

In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice.

Palmer BE, Neff CP, Lecureux J, Ehler A, Dsouza M, Remling-Mulder L, Korman AJ, Fontenot AP, Akkina R.

J Immunol. 2013 Jan 1;190(1):211-9. doi: 10.4049/jimmunol.1201108. Epub 2012 Dec 3.

32.

Infliximab therapy modulates an antigen-specific immune response in chronic beryllium disease.

Maier LA, Barkes BQ, Mroz M, Rossman MD, Barnard J, Gillespie M, Martin A, Mack DG, Silveira L, Sawyer RT, Newman LS, Fontenot AP.

Respir Med. 2012 Dec;106(12):1810-3. doi: 10.1016/j.rmed.2012.08.014. Epub 2012 Sep 11. No abstract available.

33.

Chronic beryllium disease, HLA-DPB1, and the DP peptide binding groove.

Silveira LJ, McCanlies EC, Fingerlin TE, Van Dyke MV, Mroz MM, Strand M, Fontenot AP, Bowerman N, Dabelea DM, Schuler CR, Weston A, Maier LA.

J Immunol. 2012 Oct 15;189(8):4014-23. doi: 10.4049/jimmunol.1200798. Epub 2012 Sep 12.

34.

Highly conserved CDR3 region in circulating CD4(+)Vβ5(+) T cells may be associated with cytotoxic activity in Chagas disease.

Menezes CA, Sullivan AK, Falta MT, Mack DG, Freed BM, Rocha MO, Gollob KJ, Fontenot AP, Dutra WO.

Clin Exp Immunol. 2012 Aug;169(2):109-18. doi: 10.1111/j.1365-2249.2012.04608.x.

35.

Regulatory T cells and lung fibrosis: a good cell gone bad.

Atamas SP, Fontenot AP.

Am J Respir Crit Care Med. 2011 Dec 1;184(11):1224-6. doi: 10.1164/rccm.201108-1572ED. No abstract available.

PMID:
22162882
36.

Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells.

Brindley SM, Lanham AM, Karrer FM, Tucker RM, Fontenot AP, Mack CL.

Hepatology. 2012 Apr;55(4):1130-8. doi: 10.1002/hep.24807.

37.

Beryllium-specific CD4+ T cells in blood as a biomarker of disease progression.

Martin AK, Mack DG, Falta MT, Mroz MM, Newman LS, Maier LA, Fontenot AP.

J Allergy Clin Immunol. 2011 Nov;128(5):1100-6.e1-5. doi: 10.1016/j.jaci.2011.08.022. Epub 2011 Sep 23.

38.

Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition.

Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP.

J Immunol. 2011 Oct 1;187(7):3694-703. doi: 10.4049/jimmunol.1101872. Epub 2011 Aug 26.

39.

Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease.

Goldstein JI, Kominsky DJ, Jacobson N, Bowers B, Regalia K, Austin GL, Yousefi M, Falta MT, Fontenot AP, Gerich ME, Golden-Mason L, Colgan SP.

Gastroenterology. 2011 Jul;141(1):208-16. doi: 10.1053/j.gastro.2011.03.060. Epub 2011 Apr 7.

40.

Immunomodulatory strategies prevent the development of autoimmune emphysema.

Hanaoka M, Nicolls MR, Fontenot AP, Kraskauskas D, Mack DG, Kratzer A, Salys J, Kraskauskiene V, Burns N, Voelkel NF, Taraseviciene-Stewart L.

Respir Res. 2010 Dec 16;11:179. doi: 10.1186/1465-9921-11-179.

41.

Altered immune phenotype in peripheral blood cells of patients with scleroderma-associated pulmonary hypertension.

Risbano MG, Meadows CA, Coldren CD, Jenkins TJ, Edwards MG, Collier D, Huber W, Mack DG, Fontenot AP, Geraci MW, Bull TM.

Clin Transl Sci. 2010 Oct;3(5):210-8. doi: 10.1111/j.1752-8062.2010.00218.x. Erratum in: Clin Transl Sci. 2010 Dec;3(6):340. Hunt, James [added].

42.

γδ T cells protect against lung fibrosis via IL-22.

Simonian PL, Wehrmann F, Roark CL, Born WK, O'Brien RL, Fontenot AP.

J Exp Med. 2010 Sep 27;207(10):2239-53. doi: 10.1084/jem.20100061. Epub 2010 Sep 20.

43.

Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection.

Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Golden-Mason L, Akkina R, Fontenot AP, Wilson CC, Palmer BE.

J Immunol. 2010 Sep 1;185(5):3007-18. doi: 10.4049/jimmunol.1000156. Epub 2010 Jul 23.

44.

Linking genetic susceptibility and T cell activation in beryllium-induced disease.

Falta MT, Bowerman NA, Dai S, Kappler JW, Fontenot AP.

Proc Am Thorac Soc. 2010 May;7(2):126-9. doi: 10.1513/pats.201002-022RM. Review.

45.

Crystal structure of HLA-DP2 and implications for chronic beryllium disease.

Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7425-30. doi: 10.1073/pnas.1001772107. Epub 2010 Mar 31.

46.

Deficient and dysfunctional regulatory T cells in the lungs of chronic beryllium disease subjects.

Mack DG, Lanham AM, Falta MT, Palmer BE, Maier LA, Fontenot AP.

Am J Respir Crit Care Med. 2010 Jun 1;181(11):1241-9. doi: 10.1164/rccm.201001-0025OC. Epub 2010 Mar 18.

47.

Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis.

Simonian PL, Roark CL, Born WK, O'Brien RL, Fontenot AP.

Transl Res. 2009 Nov;154(5):222-7. doi: 10.1016/j.trsl.2009.08.006. Epub 2009 Sep 9.

48.

CD27 expression on CD4+ T cells differentiates effector from regulatory T cell subsets in the lung.

Mack DG, Lanham AM, Palmer BE, Maier LA, Fontenot AP.

J Immunol. 2009 Jun 1;182(11):7317-24. doi: 10.4049/jimmunol.0804305.

49.

IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis.

Simonian PL, Roark CL, Wehrmann F, Lanham AM, Born WK, O'Brien RL, Fontenot AP.

J Immunol. 2009 May 15;182(10):6540-9. doi: 10.4049/jimmunol.0900013.

50.

Decreased 4-1BB expression on HIV-specific CD4+ T cells is associated with sustained viral replication and reduced IL-2 production.

Kassu A, D'Souza M, O'Connor BP, Kelly-McKnight E, Akkina R, Fontenot AP, Palmer BE.

Clin Immunol. 2009 Aug;132(2):234-45. doi: 10.1016/j.clim.2009.03.531. Epub 2009 Apr 29.

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