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Items: 31

1.

Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models.

Chiarot E, Spagnuolo A, Maccari S, Naimo E, Acquaviva A, Cecchi R, Galletti B, Fabbrini M, Mori E, Ruggiero P, Grandi G, Fontana MR, Bensi G, Margarit I.

Sci Rep. 2018 Feb 7;8(1):2593. doi: 10.1038/s41598-018-20609-5.

2.

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin.

Fiaschi L, Di Palo B, Scarselli M, Pozzi C, Tomaszewski K, Galletti B, Nardi-Dei V, Arcidiacono L, Mishra RP, Mori E, Pallaoro M, Falugi F, Torre A, Fontana MR, Soriani M, Bubeck Wardenburg J, Grandi G, Rappuoli R, Ferlenghi I, Bagnoli F.

Clin Vaccine Immunol. 2016 Jun 6;23(6):442-50. doi: 10.1128/CVI.00091-16. Print 2016 Jun.

3.

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.

Mancini F, Monaci E, Lofano G, Torre A, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Galletti B, Laera D, Pallaoro M, Tuscano G, Fontana MR, Bensi G, Grandi G, Rossi-Paccani S, Nuti S, Rappuoli R, De Gregorio E, Bagnoli F, Soldaini E, Bertholet S.

PLoS One. 2016 Jan 26;11(1):e0147767. doi: 10.1371/journal.pone.0147767. eCollection 2016.

4.

MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers.

Monaci E, Mancini F, Lofano G, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Giraldi M, Galletti B, Rossi Paccani S, Torre A, Fontana MR, Grandi G, de Gregorio E, Bensi G, Chiarot E, Nuti S, Bagnoli F, Soldaini E, Bertholet S.

Front Immunol. 2015 Sep 7;6:439. doi: 10.3389/fimmu.2015.00439. eCollection 2015.

5.

Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice.

Torre A, Bacconi M, Sammicheli C, Galletti B, Laera D, Fontana MR, Grandi G, De Gregorio E, Bagnoli F, Nuti S, Bertholet S, Bensi G.

Infect Immun. 2015 Aug;83(8):3157-63. doi: 10.1128/IAI.00258-15. Epub 2015 May 26.

6.

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.

Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3680-5. doi: 10.1073/pnas.1424924112. Epub 2015 Mar 9.

7.

Protectome analysis: a new selective bioinformatics tool for bacterial vaccine candidate discovery.

Altindis E, Cozzi R, Di Palo B, Necchi F, Mishra RP, Fontana MR, Soriani M, Bagnoli F, Maione D, Grandi G, Liberatori S.

Mol Cell Proteomics. 2015 Feb;14(2):418-29. doi: 10.1074/mcp.M114.039362. Epub 2014 Nov 3.

8.

SslE elicits functional antibodies that impair in vitro mucinase activity and in vivo colonization by both intestinal and extraintestinal Escherichia coli strains.

Nesta B, Valeri M, Spagnuolo A, Rosini R, Mora M, Donato P, Alteri CJ, Del Vecchio M, Buccato S, Pezzicoli A, Bertoldi I, Buzzigoli L, Tuscano G, Falduto M, Rippa V, Ashhab Y, Bensi G, Fontana MR, Seib KL, Mobley HL, Pizza M, Soriani M, Serino L.

PLoS Pathog. 2014 May 8;10(5):e1004124. doi: 10.1371/journal.ppat.1004124. eCollection 2014 May. Erratum in: PLoS Pathog. 2015 Mar;11(3):e1004773.

9.

Protective activity of the CnaBE3 domain conserved among Staphylococcus aureus Sdr proteins.

Becherelli M, Prachi P, Viciani E, Biagini M, Fiaschi L, Chiarot E, Nosari S, Brettoni C, Marchi S, Biancucci M, Fontana MR, Montagnani F, Bagnoli F, Barocchi MA, Manetti AG.

PLoS One. 2013 Sep 17;8(9):e74718. doi: 10.1371/journal.pone.0074718. eCollection 2013.

10.

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.

Schluepen C, Malito E, Marongiu A, Schirle M, McWhinnie E, Lo Surdo P, Biancucci M, Falugi F, Nardi-Dei V, Marchi S, Fontana MR, Lombardi B, De Falco MG, Rinaudo CD, Spraggon G, Nissum M, Bagnoli F, Grandi G, Bottomley MJ, Liberatori S.

Biochem J. 2013 Nov 1;455(3):273-84. doi: 10.1042/BJ20130540.

PMID:
23895222
11.

Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice.

Mishra RP, Mariotti P, Fiaschi L, Nosari S, Maccari S, Liberatori S, Fontana MR, Pezzicoli A, De Falco MG, Falugi F, Altindis E, Serruto D, Grandi G, Bagnoli F.

J Infect Dis. 2012 Oct 1;206(7):1041-9. doi: 10.1093/infdis/jis463. Epub 2012 Jul 24.

PMID:
22829645
12.

FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.

Nesta B, Spraggon G, Alteri C, Moriel DG, Rosini R, Veggi D, Smith S, Bertoldi I, Pastorello I, Ferlenghi I, Fontana MR, Frankel G, Mobley HL, Rappuoli R, Pizza M, Serino L, Soriani M.

MBio. 2012 Apr 10;3(2). pii: e00010-12. doi: 10.1128/mBio.00010-12. Print 2012.

13.

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli.

Moriel DG, Bertoldi I, Spagnuolo A, Marchi S, Rosini R, Nesta B, Pastorello I, Corea VA, Torricelli G, Cartocci E, Savino S, Scarselli M, Dobrindt U, Hacker J, Tettelin H, Tallon LJ, Sullivan S, Wieler LH, Ewers C, Pickard D, Dougan G, Fontana MR, Rappuoli R, Pizza M, Serino L.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9072-7. doi: 10.1073/pnas.0915077107. Epub 2010 May 3.

14.

The effectiveness of sealants in managing caries lesions.

Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF; CDC Dental Sealant Systematic Review Work Group, Bader J, Clarkson J, Fontana MR, Meyer DM, Rozier RG, Weintraub JA, Zero DT.

J Dent Res. 2008 Feb;87(2):169-74.

PMID:
18218845
15.

Proteomics characterization of outer membrane vesicles from the extraintestinal pathogenic Escherichia coli DeltatolR IHE3034 mutant.

Berlanda Scorza F, Doro F, Rodríguez-Ortega MJ, Stella M, Liberatori S, Taddei AR, Serino L, Gomes Moriel D, Nesta B, Fontana MR, Spagnuolo A, Pizza M, Norais N, Grandi G.

Mol Cell Proteomics. 2008 Mar;7(3):473-85. Epub 2007 Nov 2.

16.

A new in vitro model to study the relationship of gap size and secondary caries.

Totiam P, González-Cabezas C, Fontana MR, Zero DT.

Caries Res. 2007;41(6):467-73. Epub 2007 Sep 7.

PMID:
17827964
17.

Identification of a new OmpA-like protein in Neisseria gonorrhoeae involved in the binding to human epithelial cells and in vivo colonization.

Serino L, Nesta B, Leuzzi R, Fontana MR, Monaci E, Mocca BT, Cartocci E, Masignani V, Jerse AE, Rappuoli R, Pizza M.

Mol Microbiol. 2007 Jun;64(5):1391-403.

18.

[Spa therapy in urolithiasis].

Petraccia L, Mennuni G, Fontana Mr, Fraioli A.

Clin Ter. 2005 Sep-Oct;156(5):231-3. Review. Italian.

PMID:
16382972
19.

Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages.

Leuzzi R, Serino L, Scarselli M, Savino S, Fontana MR, Monaci E, Taddei A, Fischer G, Rappuoli R, Pizza M.

Mol Microbiol. 2005 Nov;58(3):669-81.

20.

Genetic detoxification of bacterial toxins.

Pizza M, Fontana MR, Scarlato V, Rappuoli R.

Methods Mol Med. 2003;87:133-52. No abstract available.

PMID:
12958454
21.

Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants.

Pizza M, Giuliani MM, Fontana MR, Monaci E, Douce G, Dougan G, Mills KH, Rappuoli R, Del Giudice G.

Vaccine. 2001 Mar 21;19(17-19):2534-41. Review.

PMID:
11257389
22.

LTK63 and LTR72, two mucosal adjuvants ready for clinical trials.

Pizza M, Giuliani MM, Fontana MR, Douce G, Dougan G, Rappuoli R.

Int J Med Microbiol. 2000 Oct;290(4-5):455-61. Review. No abstract available.

PMID:
11111926
23.

IEM101, a naturally attenuated Vibrio cholerae strain as carrier for genetically detoxified derivatives of cholera toxin.

Fontana MR, Monaci E, Yanqing L, Guoming Q, Duan G, Rappuoli R, Pizza M.

Vaccine. 2000 Aug 15;19(1):75-85.

PMID:
10924789
24.

Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop.

Giannelli V, Fontana MR, Giuliani MM, Guangcai D, Rappuoli R, Pizza M.

Infect Immun. 1997 Jan;65(1):331-4.

25.

Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin.

Magagnoli C, Manetti R, Fontana MR, Giannelli V, Giuliani MM, Rappuoli R, Pizza M.

Infect Immun. 1996 Dec;64(12):5434-8.

26.

Genetic detoxification of bacterial toxins.

Pizza M, Fontana MR, Scarlato V, Rappuoli R.

Methods Mol Med. 1996;4:91-109. doi: 10.1385/0-89603-334-1:91.

PMID:
21359697
27.

Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit.

Fontana MR, Manetti R, Giannelli V, Magagnoli C, Marchini A, Olivieri R, Domenighini M, Rappuoli R, Pizza M.

Infect Immun. 1995 Jun;63(6):2356-60.

28.

A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit.

Pizza M, Fontana MR, Giuliani MM, Domenighini M, Magagnoli C, Giannelli V, Nucci D, Hol W, Manetti R, Rappuoli R.

J Exp Med. 1994 Dec 1;180(6):2147-53.

29.

Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis.

Pizza M, Domenighini M, Hol W, Giannelli V, Fontana MR, Giuliani MM, Magagnoli C, Peppoloni S, Manetti R, Rappuoli R.

Mol Microbiol. 1994 Oct;14(1):51-60.

PMID:
7830560
30.

Processing of interleukin-1 in cells of monocytic lineage is differentiation-dependent.

Carinci V, Guida S, Fontana MR, Palla E, Rossini M, Melli M.

Eur J Biochem. 1992 Apr 1;205(1):295-301.

31.

Neurophysiological assessment of the somatosensory pathway in rheumatic patients with atlanto-axial subluxation.

Schoenhuber R, Bortolotti P, Malavasi P, Mussini C, Fontana MR, Manzini E.

Electromyogr Clin Neurophysiol. 1984 Mar-Apr;24(3):213-6. No abstract available.

PMID:
6714149

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