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The demographic and clinical characteristics of an Italian population of adult outpatients with chronic cough.

Campi G, Noale M, Fabbrizzi A, Lavorini F, Maggi S, Fontana G.

Aging Clin Exp Res. 2020 Jan 16. doi: 10.1007/s40520-019-01464-4. [Epub ahead of print]


Perfusion and diffusion in meningioma tumors: a preliminary multiparametric analysis with Dynamic Susceptibility Contrast and IntraVoxel Incoherent Motion MRI.

Zampini MA, Buizza G, Paganelli C, Fontana G, D'Ippolito E, Valvo F, Preda L, Baroni G.

Magn Reson Imaging. 2019 Dec 28;67:69-78. doi: 10.1016/j.mri.2019.12.003. [Epub ahead of print]


Virtual 4DCT from 4DMRI for the management of respiratory motion in carbon ion therapy of abdominal tumors.

Meschini G, Vai A, Paganelli C, Molinelli S, Fontana G, Pella A, Preda L, Vitolo V, Valvo F, Ciocca M, Riboldi M, Baroni G.

Med Phys. 2019 Dec 27. doi: 10.1002/mp.13992. [Epub ahead of print]


Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation.

Calverley PM, Page C, Dal Negro RW, Fontana G, Cazzola M, Cicero AF, Pozzi E, Wedzicha JA.

Int J Chron Obstruct Pulmon Dis. 2019 Dec 2;14:2733-2744. doi: 10.2147/COPD.S221852. eCollection 2019.


Compartmentalized DNA repair: Rif1 S-acylation links DNA double-strand break repair to the nuclear membrane.

Fontana GA, Rass U.

Mol Cell Oncol. 2019 Aug 21;6(6):e1648025. doi: 10.1080/23723556.2019.1648025. eCollection 2019.


Long-time clinical experience in patient setup for several particle therapy clinical indications: management of patient positioning and evaluation of setup reproducibility and stability.

Ricotti R, Pella A, Tagaste B, Elisei G, Fontana G, Bonora M, Ciocca M, Valvo F, Orecchia R, Baroni G.

Br J Radiol. 2019 Nov 14:20190595. doi: 10.1259/bjr.20190595. [Epub ahead of print]


The lung microbiome: clinical and therapeutic implications.

Fabbrizzi A, Amedei A, Lavorini F, Renda T, Fontana G.

Intern Emerg Med. 2019 Nov;14(8):1241-1250. doi: 10.1007/s11739-019-02208-y. Epub 2019 Oct 31. Review.


Mineral-Coated Microparticles Enhance mRNA-Based Transfection of Human Bone Marrow Cells.

Fontana G, Martin HL, Lee JS, Schill K, Hematti P, Murphy WL.

Mol Ther Nucleic Acids. 2019 Dec 6;18:455-464. doi: 10.1016/j.omtn.2019.09.004. Epub 2019 Sep 16.


Five reasons for optimism on World Patient Safety Day.

Fontana G, Flott K, Dhingra-Kumar N, Durkin M, Darzi A.

Lancet. 2019 Sep 21;394(10203):993-995. doi: 10.1016/S0140-6736(19)32134-8. Epub 2019 Sep 12. No abstract available.


A Review of the Phytochemistry, Traditional Uses, and Biological Activities of the Genus Ballota and Otostegia.

Rosselli S, Fontana G, Bruno M.

Planta Med. 2019 Aug;85(11-12):869-910. doi: 10.1055/a-0953-6165. Epub 2019 Jun 19. Review.


Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement.

Fontana G, Bruno M, Notarbartolo M, Labbozzetta M, Poma P, Spinella A, Rosselli S.

Bioorg Chem. 2019 Sep;90:103054. doi: 10.1016/j.bioorg.2019.103054. Epub 2019 Jun 7.


Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane.

Fontana GA, Hess D, Reinert JK, Mattarocci S, Falquet B, Klein D, Shore D, Thomä NH, Rass U.

Nat Commun. 2019 Jun 10;10(1):2535. doi: 10.1038/s41467-019-10349-z.


New understanding in the treatment of cough (NEUROCOUGH) ERS Clinical Research Collaboration: improving care and treatment for patients with cough.

McGarvey L, Dupont L, Birring SS, Boyd J, Chung KF, Dabrowska M, Domingo C, Fontana G, Guilleminault L, Kardos P, Millqvist E, Morice AH, Smith JA, van den Berg JW, Van de Kerkhove C; NEUROCOUGH Clinical Research Collaboration.

Eur Respir J. 2019 May 30;53(5). pii: 1900787. doi: 10.1183/13993003.00787-2019. Print 2019 May. No abstract available.


MRI-based tumour control probability in skull-base chordomas treated with carbon-ion therapy.

Buizza G, Molinelli S, D'Ippolito E, Fontana G, Pella A, Valvo F, Preda L, Orecchia R, Baroni G, Paganelli C.

Radiother Oncol. 2019 Aug;137:32-37. doi: 10.1016/j.radonc.2019.04.018. Epub 2019 Apr 30.


A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator.

Kerzner B, Martin HL, Weiser M, Fontana G, Russell N, Murphy WL, Lund EA, Doro CJ.

J Vis Exp. 2019 Mar 24;(145). doi: 10.3791/59206.


Antitussive therapy: A role for levodropropizine.

Birring S, de Blasio F, Dicpinigaitis PV, Fontana G, Lanata L, Page C, Saibene F, Zanasi A.

Pulm Pharmacol Ther. 2019 Jun;56:79-85. doi: 10.1016/j.pupt.2019.03.003. Epub 2019 Mar 11. Review.


Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.

Kaushik G, Gil DA, Torr E, Berge ES, Soref C, Uhl P, Fontana G, Antosiewicz-Bourget J, Edington C, Schwartz MP, Griffith LG, Thomson JA, Skala MC, Daly WT, Murphy WL.

Adv Healthc Mater. 2019 Jan;8(2):e1801186. doi: 10.1002/adhm.201801186. Epub 2018 Dec 19.


Prospective US investigational device exemption trial of a sutureless aortic bioprosthesis: One-year outcomes.

Suri RM, Javadikasgari H, Heimansohn DA, Weissman NJ, Ailawadi G, Ad N, Aldea GS, Thourani VH, Szeto WY, Michler RE, Michelena HI, Dabir R, Fontana GP, Kessler WF, Moront MG, Brunsting LA 3rd, Griffith BP, Montoya A, Subramanian S, Mostovych MA, Roselli EE.

J Thorac Cardiovasc Surg. 2019 May;157(5):1773-1782.e3. doi: 10.1016/j.jtcvs.2018.08.121. Epub 2018 Oct 23.


The pathogenetic mechanisms of cough in idiopathic pulmonary fibrosis.

Bargagli E, Di Masi M, Perruzza M, Vietri L, Bergantini L, Torricelli E, Biadene G, Fontana G, Lavorini F.

Intern Emerg Med. 2019 Jan;14(1):39-43. doi: 10.1007/s11739-018-1960-5. Epub 2018 Sep 29. Review.


Early commercial experience from transcatheter aortic valve implantation using the Portico™ bioprosthetic valve: 30-day outcomes in the multicentre PORTICO-1 study.

Maisano F, Worthley S, Rodés-Cabau J, Linke AH, Fichtlscherer S, Schäfer U, Makkar RR, Fontana G, Asch FM, Søndergaard L.

EuroIntervention. 2018 Oct 20;14(8):886-893. doi: 10.4244/EIJ-D-18-00343.


Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.

Fontana GA, Reinert JK, Thomä NH, Rass U.

Microb Cell. 2018 May 17;5(7):327-343. doi: 10.15698/mic2018.07.639. Review.


Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.

Adamski M, Fontana G, Gershlak JR, Gaudette GR, Le HD, Murphy WL.

J Vis Exp. 2018 May 31;(135). doi: 10.3791/57586.


MRI evaluation of sacral chordoma treated with carbon ion radiotherapy alone.

Preda L, Stoppa D, Fiore MR, Fontana G, Camisa S, Sacchi R, Ghitti M, Viselner G, Fossati P, Valvo F, Vitolo V, Bonora M, Iannalfi A, Vischioni B, Vai A, Mastella E, Baroni G, Orecchia R.

Radiother Oncol. 2018 Aug;128(2):203-208. doi: 10.1016/j.radonc.2017.11.029. Epub 2017 Dec 23.


Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells.

Khalil AS, Yu X, Xie AW, Fontana G, Umhoefer JM, Johnson HJ, Hookway TA, McDevitt TC, Murphy WL.

Sci Rep. 2017 Oct 27;7(1):14211. doi: 10.1038/s41598-017-14153-x.


Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study.

Dal Negro RW, Wedzicha JA, Iversen M, Fontana G, Page C, Cicero AF, Pozzi E, Calverley PMA; RESTORE group; RESTORE study.

Eur Respir J. 2017 Oct 12;50(4). pii: 1700711. doi: 10.1183/13993003.00711-2017. Print 2017 Oct.


A Novel Method and Mechanism for Micro-Sphere Singularization.

Fontana G, Ruggeri S, Altissimo L, Legnani G, Fassi I.

Micromachines (Basel). 2017 Sep 8;8(9). pii: E273. doi: 10.3390/mi8090273.


Can we reliably predict the level of anticoagulation after enoxaparin injection in elderly patients with renal failure?

Pellizzari L, Facchinetti R, Corrà L, Sepe A, Fantin F, Fontana G, Zamboni M, Di Francesco V.

Aging Clin Exp Res. 2018 Jun;30(6):605-608. doi: 10.1007/s40520-017-0822-8. Epub 2017 Aug 14.


A high-urgency stroke code reduces in-hospital delays in acute ischemic stroke: a single-centre experience.

Candelaresi P, Lattuada P, Uggetti C, Daccò R, Fontana G, Frediani F.

Neurol Sci. 2017 Sep;38(9):1671-1676. doi: 10.1007/s10072-017-3046-y. Epub 2017 Jun 30.


How to harness the private sector for universal health coverage.

Wadge H, Roy R, Sripathy A, Fontana G, Marti J, Darzi A.

Lancet. 2017 Jul 8;390(10090):e19-e20. doi: 10.1016/S0140-6736(17)31718-X. Epub 2017 Jun 23. No abstract available.


Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.

Mattarocci S, Reinert JK, Bunker RD, Fontana GA, Shi T, Klein D, Cavadini S, Faty M, Shyian M, Hafner L, Shore D, Thomä NH, Rass U.

Nat Struct Mol Biol. 2017 Jul;24(7):588-595. doi: 10.1038/nsmb.3420. Epub 2017 Jun 12.


A 57-year-old chronic cougher with somatically evoked cough.

Lavorini F, Fontana GA.

Pulm Pharmacol Ther. 2017 Dec;47:56-58. doi: 10.1016/j.pupt.2017.05.014. Epub 2017 May 28. No abstract available.


Mid-infrared coincidence measurements on twin photons at room temperature.

Mancinelli M, Trenti A, Piccione S, Fontana G, Dam JS, Tidemand-Lichtenberg P, Pedersen C, Pavesi L.

Nat Commun. 2017 May 15;8:15184. doi: 10.1038/ncomms15184.


Clinical Trial Principles and Endpoint Definitions for Paravalvular Leaks in Surgical Prosthesis.

Ruiz CE, Hahn RT, Berrebi A, Borer JS, Cutlip DE, Fontana G, Gerosa G, Ibrahim R, Jelnin V, Jilaihawi H, Jolicoeur EM, Kliger C, Kronzon I, Leipsic J, Maisano F, Millan X, Nataf P, O'Gara PT, Pibarot P, Ramee SR, Rihal CS, Rodes-Cabau J, Sorajja P, Suri R, Swain JA, Turi ZG, Tuzcu EM, Weissman NJ, Zamorano JL, Serruys PW, Leon MB; Paravalvular Leak Academic Research Consortium.

Eur Heart J. 2018 Apr 14;39(15):1224-1245. doi: 10.1093/eurheartj/ehx211.


Clinical Trial Principles and Endpoint Definitions for Paravalvular Leaks in Surgical Prosthesis: An Expert Statement.

Ruiz CE, Hahn RT, Berrebi A, Borer JS, Cutlip DE, Fontana G, Gerosa G, Ibrahim R, Jelnin V, Jilaihawi H, Jolicoeur EM, Kliger C, Kronzon I, Leipsic J, Maisano F, Millan X, Nataf P, O'Gara PT, Pibarot P, Ramee SR, Rihal CS, Rodes-Cabau J, Sorajja P, Suri R, Swain JA, Turi ZG, Tuzcu EM, Weissman NJ, Zamorano JL, Serruys PW, Leon MB; Paravalvular Leak Academic Research Consortium.

J Am Coll Cardiol. 2017 Apr 25;69(16):2067-2087. doi: 10.1016/j.jacc.2017.02.038. Review.


Health care must mean safe care: enshrining patient safety in global health.

Flott K, Fontana G, Dhingra-Kumar N, Yu A, Durkin M, Darzi A.

Lancet. 2017 Apr 1;389(10076):1279-1281. doi: 10.1016/S0140-6736(17)30868-1. No abstract available.


Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study.

Chakravarty T, Søndergaard L, Friedman J, De Backer O, Berman D, Kofoed KF, Jilaihawi H, Shiota T, Abramowitz Y, Jørgensen TH, Rami T, Israr S, Fontana G, de Knegt M, Fuchs A, Lyden P, Trento A, Bhatt DL, Leon MB, Makkar RR; RESOLVE; SAVORY Investigators.

Lancet. 2017 Jun 17;389(10087):2383-2392. doi: 10.1016/S0140-6736(17)30757-2. Epub 2017 Mar 19.


Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture.

Fontana G, Gershlak J, Adamski M, Lee JS, Matsumoto S, Le HD, Binder B, Wirth J, Gaudette G, Murphy WL.

Adv Healthc Mater. 2017 Apr;6(8). doi: 10.1002/adhm.201601225. Epub 2017 Mar 20.


Crossing kingdoms: Using decellularized plants as perfusable tissue engineering scaffolds.

Gershlak JR, Hernandez S, Fontana G, Perreault LR, Hansen KJ, Larson SA, Binder BY, Dolivo DM, Yang T, Dominko T, Rolle MW, Weathers PJ, Medina-Bolivar F, Cramer CL, Murphy WL, Gaudette GR.

Biomaterials. 2017 May;125:13-22. doi: 10.1016/j.biomaterials.2017.02.011. Epub 2017 Feb 10.


A Randomized Clinical Trial Comparing the Effects of Antitussive Agents on Respiratory Center Output in Patients With Chronic Cough.

Mannini C, Lavorini F, Zanasi A, Saibene F, Lanata L, Fontana G.

Chest. 2017 Jun;151(6):1288-1294. doi: 10.1016/j.chest.2017.02.001. Epub 2017 Feb 10.


Flood dynamics in urbanised landscapes: 100 years of climate and humans' interaction.

Sofia G, Roder G, Dalla Fontana G, Tarolli P.

Sci Rep. 2017 Jan 12;7:40527. doi: 10.1038/srep40527.


Minimally Invasive Robotically Assisted Repair of Partial Anomalous Venous Connection.

Pirelli L, Kliger CA, Patel NC, Bono M, Ruiz CE, Jelnin V, Fontana GP.

Innovations (Phila). 2017 Jan/Feb;12(1):71-73. doi: 10.1097/IMI.0000000000000323.


Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1.

Ölmezer G, Levikova M, Klein D, Falquet B, Fontana GA, Cejka P, Rass U.

Nat Commun. 2016 Oct 25;7:13157. doi: 10.1038/ncomms13157.


MRI quantification of pancreas motion as a function of patient setup for particle therapy -a preliminary study.

Fontana G, Riboldi M, Gianoli C, Chirvase CI, Villa G, Paganelli C, Summers PE, Tagaste B, Pella A, Fossati P, Ciocca M, Baroni G, Valvo F, Orecchia R.

J Appl Clin Med Phys. 2016 Sep 8;17(5):60-75. doi: 10.1120/jacmp.v17i5.6236.


Oxidative stress controls the choice of alternative last exons via a Brahma-BRCA1-CstF pathway.

Fontana GA, Rigamonti A, Lenzken SC, Filosa G, Alvarez R, Calogero R, Bianchi ME, Barabino SM.

Nucleic Acids Res. 2017 Jan 25;45(2):902-914. doi: 10.1093/nar/gkw780. Epub 2016 Sep 2.


Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study.

Lavorini F, Spina D, Walker MJ, Franciosi L, Page CP, Fontana GA.

Pulm Pharmacol Ther. 2016 Oct;40:91-4. doi: 10.1016/j.pupt.2016.08.001. Epub 2016 Aug 15.


Prospective study of the efficacy of antibiotics versus antitussive drugs for the management of URTI-related acute cough in children.

Zanasi A, Lanata L, Saibene F, Fontana G, Dicpinigaitis PV, Venier V, De Blasio F.

Multidiscip Respir Med. 2016 Jun 13;11:29. doi: 10.1186/s40248-016-0059-y. eCollection 2016.


Message From the President.

Fontana GP.

Innovations (Phila). 2016 May;11 Suppl 1:S27-8. doi: 10.1097/IMI.0000000000000261. No abstract available.


Optimising Inhaled Pharmacotherapy for Elderly Patients with Chronic Obstructive Pulmonary Disease: The Importance of Delivery Devices.

Lavorini F, Mannini C, Chellini E, Fontana GA.

Drugs Aging. 2016 Jul;33(7):461-73. doi: 10.1007/s40266-016-0377-y. Review.


Clinical evaluation of 4D PET motion compensation strategies for treatment verification in ion beam therapy.

Gianoli C, Kurz C, Riboldi M, Bauer J, Fontana G, Baroni G, Debus J, Parodi K.

Phys Med Biol. 2016 Jun 7;61(11):4141-55. doi: 10.1088/0031-9155/61/11/4141. Epub 2016 May 18.


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