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Items: 1 to 50 of 506

1.

Immune modulatory effects of ibrutinib in pancreatic ductal adenocarcinoma.

Sinha M, Griffith M, Betts C, Choe G, Sivagnanam S, Cheung A, Tamaki W, Liu E, Sudduth-Klinger J, Vaccaro G, Lopez C, Fong L, Coussens L, Tempero M.

Ann Oncol. 2019 Jul;30 Suppl 4:iv40. doi: 10.1093/annonc/mdz155.145. Epub 2019 Dec 4. No abstract available.

PMID:
32085149
2.

Ibrutinib in combination with nab-paclitaxel and gemcitabine as first-line treatment for patients with metastatic pancreatic adenocarcinoma: results from the phase 3 RESOLVE study.

Tempero M, Oh D, Macarulla T, Reni M, Van Cutsem E, Hendifar A, Waldschmidt D, Starling N, Bachet J, Chang H, Maurel J, Lonardi S, Coussens L, Fong L, Tsao L, Cole G Jr, James D, Tabernero J.

Ann Oncol. 2019 Jul;30 Suppl 4:iv126. doi: 10.1093/annonc/mdz154.001. Epub 2019 Dec 4. No abstract available.

PMID:
32085015
3.

Tissue Determinants of Human NK Cell Development, Function, and Residence.

Dogra P, Rancan C, Ma W, Toth M, Senda T, Carpenter DJ, Kubota M, Matsumoto R, Thapa P, Szabo PA, Li Poon MM, Li J, Arakawa-Hoyt J, Shen Y, Fong L, Lanier LL, Farber DL.

Cell. 2020 Feb 20;180(4):749-763.e13. doi: 10.1016/j.cell.2020.01.022. Epub 2020 Feb 13.

PMID:
32059780
4.

TCR Convergence in Individuals Treated With Immune Checkpoint Inhibition for Cancer.

Looney TJ, Topacio-Hall D, Lowman G, Conroy J, Morrison C, Oh D, Fong L, Zhang L.

Front Immunol. 2020 Jan 9;10:2985. doi: 10.3389/fimmu.2019.02985. eCollection 2019.

5.

Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores.

Heizer PJ, Yang Y, Tu Y, Kim PH, Chen NY, Hu Y, Yoshinaga Y, de Jong PJ, Vergnes L, Morales JE, Li RL, Jackson NJ, Reue K, Young SG, Fong LG.

J Lipid Res. 2020 Jan 15. pii: jlr.RA119000593. doi: 10.1194/jlr.RA119000593. [Epub ahead of print]

6.

Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses.

Greaney SK, Algazi AP, Tsai KK, Takamura KT, Chen L, Twitty CG, Zhang L, Paciorek A, Pierce RH, Le MH, Daud AI, Fong L.

Cancer Immunol Res. 2020 Feb;8(2):246-254. doi: 10.1158/2326-6066.CIR-19-0359. Epub 2019 Dec 18.

7.

An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death.

Chen NY, Yang Y, Weston TA, Belling JN, Heizer P, Tu Y, Kim P, Edillo L, Jonas SJ, Weiss PS, Fong LG, Young SG.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25870-25879. doi: 10.1073/pnas.1917225116. Epub 2019 Dec 3.

PMID:
31796586
8.

Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells.

Almenar-Queralt A, Merkurjev D, Kim HS, Navarro M, Ma Q, Chaves RS, Allegue C, Driscoll SP, Chen AG, Kohlnhofer B, Fong LK, Woodruff G, Mackintosh C, Bohaciakova D, Hruska-Plochan M, Tadokoro T, Young JE, El Hajj N, Dittrich M, Marsala M, Goldstein LSB, Garcia-Bassets I.

Nat Genet. 2019 Dec;51(12):1691-1701. doi: 10.1038/s41588-019-0526-4. Epub 2019 Nov 18.

PMID:
31740836
9.

Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer.

Fong L, Hotson A, Powderly JD, Sznol M, Heist RS, Choueiri TK, George S, Hughes BGM, Hellmann MD, Shepard DR, Rini BI, Kummar S, Weise AM, Riese MJ, Markman B, Emens LA, Mahadevan D, Luke JJ, Laport G, Brody JD, Hernandez-Aya L, Bonomi P, Goldman JW, Berim L, Renouf DJ, Goodwin RA, Munneke B, Ho PY, Hsieh J, McCaffery I, Kwei L, Willingham SB, Miller RA.

Cancer Discov. 2020 Jan;10(1):40-53. doi: 10.1158/2159-8290.CD-19-0980. Epub 2019 Nov 15.

10.

Phase II Trial of a DNA Vaccine Encoding Prostatic Acid Phosphatase (pTVG-HP [MVI-816]) in Patients With Progressive, Nonmetastatic, Castration-Sensitive Prostate Cancer.

McNeel DG, Eickhoff JC, Johnson LE, Roth AR, Perk TG, Fong L, Antonarakis ES, Wargowski E, Jeraj R, Liu G.

J Clin Oncol. 2019 Dec 20;37(36):3507-3517. doi: 10.1200/JCO.19.01701. Epub 2019 Oct 23.

PMID:
31644357
11.

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response.

Keenan BP, Fong L, Kelley RK.

J Immunother Cancer. 2019 Oct 18;7(1):267. doi: 10.1186/s40425-019-0749-z. Review.

12.

Complete atrioventricular septal defect repair in Australia: Results over 25 years.

Fong LS, Betts K, Bell D, Konstantinov IE, Nicholson IA, Winlaw DS, Orr Y; Australian CAVSD Study Group.

J Thorac Cardiovasc Surg. 2020 Mar;159(3):1014-1025.e8. doi: 10.1016/j.jtcvs.2019.08.005. Epub 2019 Aug 30.

PMID:
31590953
13.

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.

Li N, Wang Y, Neri S, Zhen Y, Fong LWR, Qiao Y, Li X, Chen Z, Stephan C, Deng W, Ye R, Jiang W, Zhang S, Yu Y, Hung MC, Chen J, Lin SH.

Nat Commun. 2019 Sep 25;10(1):4363. doi: 10.1038/s41467-019-12377-1.

14.

Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review.

Razali NNM, Ng CT, Fong LY.

Planta Med. 2019 Nov;85(16):1203-1215. doi: 10.1055/a-1008-6138. Epub 2019 Sep 20. Review.

PMID:
31539918
15.

Malaysian Tualang Honey Inhibits Hydrogen Peroxide-Induced Endothelial Hyperpermeability.

Devasvaran K, Tan JJ, Ng CT, Fong LY, Yong YK.

Oxid Med Cell Longev. 2019 Aug 18;2019:1202676. doi: 10.1155/2019/1202676. eCollection 2019.

16.

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia.

Hu X, Weston TA, He C, Jung RS, Heizer PJ, Young BD, Tu Y, Tontonoz P, Wohlschlegel JA, Jiang H, Young SG, Fong LG.

Elife. 2019 Sep 5;8. pii: e50231. doi: 10.7554/eLife.50231.

17.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

Pech MF, Fong LE, Villalta JE, Chan LJ, Kharbanda S, O'Brien JJ, McAllister FE, Firestone AJ, Jan CH, Settleman J.

Elife. 2019 Aug 27;8. pii: e47362. doi: 10.7554/eLife.47362.

18.

Segmenting Chinese Gamblers Based on Gambling Forms: A Latent Class Analysis.

Nong SZ, Fong LHN, Fong DKC, Lam D.

J Gambl Stud. 2020 Mar;36(1):141-159. doi: 10.1007/s10899-019-09877-6.

PMID:
31325014
19.

Modified-Single Patch vs Double Patch Repair of Complete Atrioventricular Septal Defects.

Fong LS, Betts K, Kannekanti R, Ayer J, Winlaw DS, Orr Y.

Semin Thorac Cardiovasc Surg. 2019 Jul 12. pii: S1043-0679(19)30187-X. doi: 10.1053/j.semtcvs.2019.07.004. [Epub ahead of print]

PMID:
31306766
20.

DYT1 Dystonia Patient-Derived Fibroblasts Have Increased Deformability and Susceptibility to Damage by Mechanical Forces.

Gill NK, Ly C, Kim PH, Saunders CA, Fong LG, Young SG, Luxton GWG, Rowat AC.

Front Cell Dev Biol. 2019 Jun 26;7:103. doi: 10.3389/fcell.2019.00103. eCollection 2019.

21.

GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism.

Young SG, Fong LG, Beigneux AP, Allan CM, He C, Jiang H, Nakajima K, Meiyappan M, Birrane G, Ploug M.

Cell Metab. 2019 Jul 2;30(1):51-65. doi: 10.1016/j.cmet.2019.05.023. Review.

PMID:
31269429
22.

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.

Hu X, Matsumoto K, Jung RS, Weston TA, Heizer PJ, He C, Sandoval NP, Allan CM, Tu Y, Vinters HV, Liau LM, Ellison RM, Morales JE, Baufeld LJ, Bayley NA, He L, Betsholtz C, Beigneux AP, Nathanson DA, Gerhardt H, Young SG, Fong LG, Jiang H.

Elife. 2019 Jun 6;8. pii: e47178. doi: 10.7554/eLife.47178.

23.

Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer-A Phase 1 Study.

Uldrick TS, Gonçalves PH, Abdul-Hay M, Claeys AJ, Emu B, Ernstoff MS, Fling SP, Fong L, Kaiser JC, Lacroix AM, Lee SY, Lundgren LM, Lurain K, Parsons CH, Peeramsetti S, Ramaswami R, Sharon E, Sznol M, Wang CJ, Yarchoan R, Cheever MA; Cancer Immunotherapy Trials Network (CITN)-12 Study Team.

JAMA Oncol. 2019 Jun 2. doi: 10.1001/jamaoncol.2019.2244. [Epub ahead of print]

PMID:
31154457
24.

Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up.

Fradet Y, Bellmunt J, Vaughn DJ, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Nam K, Frenkl TL, Perini RF, de Wit R, Bajorin DF.

Ann Oncol. 2019 Jun 1;30(6):970-976. doi: 10.1093/annonc/mdz127.

25.
26.

Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.

Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R.

Cell. 2019 Apr 4;177(2):414-427.e13. doi: 10.1016/j.cell.2019.02.016.

27.

Lipoprotein lipase is active as a monomer.

Beigneux AP, Allan CM, Sandoval NP, Cho GW, Heizer PJ, Jung RS, Stanhope KL, Havel PJ, Birrane G, Meiyappan M, Gill JE 4th, Murakami M, Miyashita K, Nakajima K, Ploug M, Fong LG, Young SG.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6319-6328. doi: 10.1073/pnas.1900983116. Epub 2019 Mar 8.

28.

Adnexal mass staging CT with a disease-specific structured report compared to simple structured report.

Franconeri A, Boos J, Fang J, Shenoy-Bhangle A, Perillo M, Wei CJ, Garrett L, Esselen K, Fong L, Brook OR.

Eur Radiol. 2019 Sep;29(9):4851-4860. doi: 10.1007/s00330-019-06037-7. Epub 2019 Feb 28.

PMID:
30820722
29.

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Pai CS, Huang JT, Lu X, Simons DM, Park C, Chang A, Tamaki W, Liu E, Roybal KT, Seagal J, Chen M, Hagihara K, Wei XX, DuPage M, Kwek SS, Oh DY, Daud A, Tsai KK, Wu C, Zhang L, Fasso M, Sachidanandam R, Jayaprakash A, Lin I, Casbon AJ, Kinsbury GA, Fong L.

Immunity. 2019 Feb 19;50(2):477-492.e8. doi: 10.1016/j.immuni.2019.01.006. Epub 2019 Feb 5.

30.

Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma.

Xu J, Chang WH, Fong LWR, Weiss RH, Yu SL, Chen CH.

Signal Transduct Target Ther. 2019 Jan 25;4:2. doi: 10.1038/s41392-019-0035-z. eCollection 2019.

31.

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.

van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB.

Cell Stem Cell. 2019 Mar 7;24(3):363-375.e9. doi: 10.1016/j.stem.2018.12.013. Epub 2019 Jan 24.

32.

Biodegradable bioadhesive nanoparticle incorporation of broad-spectrum organic sunscreen agents.

Suh HW, Lewis J, Fong L, Ramseier JY, Carlson K, Peng ZH, Yin ES, Saltzman WM, Girardi M.

Bioeng Transl Med. 2018 Jul 6;4(1):129-140. doi: 10.1002/btm2.10092. eCollection 2019 Jan.

33.

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner.

Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Morales JE, Sajti E, Troutman TD, Saunders TL, Cusanovich DA, Beigneux AP, Romanoski CE, Fong LG, Young SG.

J Lipid Res. 2019 Apr;60(4):869-879. doi: 10.1194/jlr.M091322. Epub 2018 Dec 31.

PMID:
30598475
34.

Immunity in the Time of Metastases.

Oh DY, Fong L.

Immunity. 2018 Dec 18;49(6):1002-1003. doi: 10.1016/j.immuni.2018.12.008.

35.

Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.

Birrane G, Beigneux AP, Dwyer B, Strack-Logue B, Kristensen KK, Francone OL, Fong LG, Mertens HDT, Pan CQ, Ploug M, Young SG, Meiyappan M.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1723-1732. doi: 10.1073/pnas.1817984116. Epub 2018 Dec 17.

36.

Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer.

Hagihara K, Chan S, Zhang L, Oh DY, Wei XX, Simko J, Fong L.

Oncoimmunology. 2018 Oct 1;8(1):e1486953. doi: 10.1080/2162402X.2018.1486953. eCollection 2019.

37.

Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.

Pai CS, Simons DM, Lu X, Evans M, Wei J, Wang YH, Chen M, Huang J, Park C, Chang A, Wang J, Westmoreland S, Beam C, Banach D, Bowley D, Dong F, Seagal J, Ritacco W, Richardson PL, Mitra S, Lynch G, Bousquet P, Mankovich J, Kingsbury G, Fong L.

J Clin Invest. 2019 Jan 2;129(1):349-363. doi: 10.1172/JCI123391. Epub 2018 Dec 10.

38.

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.

Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K.

J Clin Invest. 2019 Jan 2;129(1):281-295. doi: 10.1172/JCI122595. Epub 2018 Dec 3.

39.

Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats.

Fong LY, Jing R, Smalley KJ, Wang ZX, Taccioli C, Fan S, Chen H, Alder H, Huebner K, Farber JL, Fiehn O, Croce CM.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11091-E11100. doi: 10.1073/pnas.1813956115. Epub 2018 Nov 5.

40.

A Review of TENIS Syndrome in Hospital Pulau Pinang.

Khoo ACH, Fong LY, Hamzah F.

Indian J Nucl Med. 2018 Oct-Dec;33(4):284-289. doi: 10.4103/ijnm.IJNM_65_18.

41.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Oct 18;175(3):889. doi: 10.1016/j.cell.2018.10.019. No abstract available.

42.

Itraconazole as a Noncastrating Treatment for Biochemically Recurrent Prostate Cancer: A Phase 2 Study.

Lee M, Hong H, Kim W, Zhang L, Friedlander TW, Fong L, Lin AM, Small EJ, Wei XX, Rodvelt TJ, Miralda B, Stocksdale B, Ryan CJ, Aggarwal R.

Clin Genitourin Cancer. 2019 Feb;17(1):e92-e96. doi: 10.1016/j.clgc.2018.09.013. Epub 2018 Sep 24.

PMID:
30327180
43.

The Immune Landscape of Prostate Cancer and Nomination of PD-L2 as a Potential Therapeutic Target.

Zhao SG, Lehrer J, Chang SL, Das R, Erho N, Liu Y, Sjöström M, Den RB, Freedland SJ, Klein EA, Karnes RJ, Schaeffer EM, Xu M, Speers C, Nguyen PL, Ross AE, Chan JM, Cooperberg MR, Carroll PR, Davicioni E, Fong L, Spratt DE, Feng FY.

J Natl Cancer Inst. 2019 Mar 1;111(3):301-310. doi: 10.1093/jnci/djy141.

PMID:
30321406
44.

Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T.

Nat Med. 2018 Dec;24(12):1941. doi: 10.1038/s41591-018-0235-z.

PMID:
30291359
45.

Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.

Levy Y, Ross JA, Niglas M, Snetkov VA, Lynham S, Liao CY, Puckelwartz MJ, Hsu YM, McNally EM, Alsheimer M, Harridge SD, Young SG, Fong LG, Español Y, Lopez-Otin C, Kennedy BK, Lowe DA, Ochala J.

JCI Insight. 2018 Oct 4;3(19). pii: 120920. doi: 10.1172/jci.insight.120920.

46.

Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome.

Kim PH, Luu J, Heizer P, Tu Y, Weston TA, Chen N, Lim C, Li RL, Lin PY, Dunn JCY, Hodzic D, Young SG, Fong LG.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7163. doi: 10.1126/scitranslmed.aat7163.

47.

Is the modified single-patch repair superior to the double-patch repair of complete atrioventricular septal defects?

Fong LS, Winlaw DS, Orr Y.

Interact Cardiovasc Thorac Surg. 2019 Mar 1;28(3):427-431. doi: 10.1093/icvts/ivy261. Review.

PMID:
30239715
48.

A Preclinical Assessment of 89Zr-atezolizumab Identifies a Requirement for Carrier Added Formulations Not Observed with 89Zr-C4.

Moroz A, Lee CY, Wang YH, Hsiao JC, Sevillano N, Truillet C, Craik CS, Fong L, Wang CI, Evans MJ.

Bioconjug Chem. 2018 Oct 17;29(10):3476-3482. doi: 10.1021/acs.bioconjchem.8b00632. Epub 2018 Sep 24.

49.

Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures.

Chen NY, Kim P, Weston TA, Edillo L, Tu Y, Fong LG, Young SG.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10100-10105. doi: 10.1073/pnas.1812622115. Epub 2018 Sep 17.

50.

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.

He C, Hu X, Weston TA, Jung RS, Heizer P, Tu Y, Ellison R, Matsumoto K, Gerhardt H, Tontonoz P, Fong LG, Young SG, Jiang H.

Biochem Biophys Res Commun. 2018 Oct 12;504(4):899-902. doi: 10.1016/j.bbrc.2018.09.051. Epub 2018 Sep 15.

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