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Items: 1 to 50 of 109

1.

Age at onset in genetic prion disease and the design of preventive clinical trials.

Minikel EV, Vallabh SM, Orseth MC, Brandel JP, Haïk S, Laplanche JL, Zerr I, Parchi P, Capellari S, Safar J, Kenny J, Fong JC, Takada LT, Ponto C, Hermann P, Knipper T, Stehmann C, Kitamoto T, Ae R, Hamaguchi T, Sanjo N, Tsukamoto T, Mizusawa H, Collins SJ, Chiesa R, Roiter I, de Pedro-Cuesta J, Calero M, Geschwind MD, Yamada M, Nakamura Y, Mead S.

Neurology. 2019 Jul 9;93(2):e125-e134. doi: 10.1212/WNL.0000000000007745. Epub 2019 Jun 6.

PMID:
31171647
2.

Holt-Oram Syndrome.

McDermott DA, Fong JC, Basson CT.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2004 Jul 20 [updated 2019 May 23].

3.

Precision medicine for a man presented with diabetes at 2-month old.

Ang SF, Tan CSH, Fong JCW, Lim SC.

Eur J Hum Genet. 2019 Jun;27(6):989-993. doi: 10.1038/s41431-019-0371-z. Epub 2019 Mar 19.

PMID:
30890782
4.

PAX4 R192H is associated with younger onset of Type 2 diabetes in East Asians in Singapore.

Ang SF, Tan CSH, Wang L, Dorajoo R, Fong JCW, Kon WYC, Lian JX, Ang K, Rahim JB, Jeevith B, Lee SBM, Tang WE, Subramanium T, Sum CF, Liu JJ, Lim SC.

J Diabetes Complications. 2019 Jan;33(1):53-58. doi: 10.1016/j.jdiacomp.2018.10.002. Epub 2018 Oct 13.

PMID:
30528630
5.

Directed evolution and biophysical characterization of a full-length, soluble, human caveolin-1 variant.

Smith JN, Edgar JM, Balk JM, Iftikhar M, Fong JC, Olsen TJ, Fishman DA, Majumdar S, Weiss GA.

Biochim Biophys Acta Proteins Proteom. 2018 Sep;1866(9):963-972. doi: 10.1016/j.bbapap.2018.05.014. Epub 2018 May 29.

PMID:
29857161
6.

Understanding breast cancer screening--past, present, and future.

Sitt JC, Lui CY, Sinn LH, Fong JC.

Hong Kong Med J. 2018 Apr;24(2):166-174. doi: 10.12809/hkmj177123. Epub 2017 Apr 6. Review.

7.

Spectrum of mutations in index patients with familial hypercholesterolemia in Singapore: Single center study.

Pek SLT, Dissanayake S, Fong JCW, Lin MX, Chan EZL, Tang JI, Lee CW, Ong HY, Sum CF, Lim SC, Tavintharan S.

Atherosclerosis. 2018 Feb;269:106-116. doi: 10.1016/j.atherosclerosis.2017.12.028. Epub 2017 Dec 27.

PMID:
29353225
8.

Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts.

Steele NZ, Bright AR, Lee SE, Fong JC, Bonham LW, Karydas A, Karbassi ID, Pribadi M, Meservey MA, Gallen MC, Ramos EM, Liaquat K, Hoffman CC, Krasner MR, Dodge W, L Miller B, Coppola G, Rankin KP, Yokoyama JS, Higgins JJ.

Adv Genomics Genet. 2018;8:23-33. doi: 10.2147/AGG.S164047. Epub 2018 Oct 25.

9.

Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia.

Olney NT, Alquezar C, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, De May M, Seeley WW, Coppola G, Miller BL, Kao AW.

Acta Neuropathol. 2017 Nov;134(5):813-816. doi: 10.1007/s00401-017-1764-0. Epub 2017 Aug 21. No abstract available.

10.

Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms.

Fong JC, Rogers A, Michael AK, Parsley NC, Cornell WC, Lin YC, Singh PK, Hartmann R, Drescher K, Vinogradov E, Dietrich LE, Partch CL, Yildiz FH.

Elife. 2017 Aug 1;6. pii: e26163. doi: 10.7554/eLife.26163.

11.

Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer.

Read ML, Fong JC, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson RJ, Nieto H, Reynolds JJ, Bacon A, Mallick U, Hackshaw A, Watkinson JC, Boelaert K, Turnell AS, Smith VE, McCabe CJ.

Oncogene. 2017 Sep 14;36(37):5296-5308. doi: 10.1038/onc.2017.154. Epub 2017 May 15.

12.

Genetic prion disease: Experience of a rapidly progressive dementia center in the United States and a review of the literature.

Takada LT, Kim MO, Cleveland RW, Wong K, Forner SA, Gala II, Fong JC, Geschwind MD.

Am J Med Genet B Neuropsychiatr Genet. 2017 Jan;174(1):36-69. doi: 10.1002/ajmg.b.32505. Review.

PMID:
27943639
13.

Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy.

Fong JC, Rojas JC, Bang J, Legati A, Rankin KP, Forner S, Miller ZA, Karydas AM, Coppola G, Grouse CK, Ralph J, Miller BL, Geschwind MD.

J Alzheimers Dis. 2017;55(1):249-258.

14.

A preliminary study to evaluate the strategy of combining clinical criteria and next generation sequencing (NGS) for the identification of monogenic diabetes among multi-ethnic Asians.

Ang SF, Lim SC, Tan CSh, Fong JC, Kon WY, Lian JX, Subramanium T, Sum CF.

Diabetes Res Clin Pract. 2016 Sep;119:13-22. doi: 10.1016/j.diabres.2016.06.008. Epub 2016 Jul 1.

PMID:
27420379
15.

Young-onset frontotemporal dementia in a homozygous tau R406W mutation carrier.

Ng AS, Sias AC, Pressman PS, Fong JC, Karydas AM, Zanto TP, De May M, Coppola G, Geschwind DH, Miller BL, Lee SE.

Ann Clin Transl Neurol. 2015 Nov 12;2(12):1124-8. doi: 10.1002/acn3.265. eCollection 2015 Dec.

16.

Frontotemporal Dementia and Psychiatric Illness: Emerging Clinical and Biological Links in Gene Carriers.

Block NR, Sha SJ, Karydas AM, Fong JC, De May MG, Miller BL, Rosen HJ.

Am J Geriatr Psychiatry. 2016 Feb;24(2):107-16. doi: 10.1016/j.jagp.2015.04.007. Epub 2015 Jun 21.

17.

The effect of chronic liver disease on venous thromboembolism among medically managed patients in Singapore General Hospital.

Yang Y, Zhang XZ, Ng HS, Fong JC, Lee LH.

Thromb Res. 2015 Sep;136(3):548-51. doi: 10.1016/j.thromres.2015.06.033. Epub 2015 Jul 6.

PMID:
26164397
18.

Synergistic induction of insulin resistance by endothelin-1 and cAMP in 3T3-L1 adipocytes.

Chai SP, Fong JC.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2048-55. doi: 10.1016/j.bbadis.2015.06.026. Epub 2015 Jul 2.

19.

Identification and characterization of VpsR and VpsT binding sites in Vibrio cholerae.

Zamorano-Sánchez D, Fong JC, Kilic S, Erill I, Yildiz FH.

J Bacteriol. 2015 Apr;197(7):1221-35. doi: 10.1128/JB.02439-14. Epub 2015 Jan 26.

20.

Polymyxin B resistance and biofilm formation in Vibrio cholerae are controlled by the response regulator CarR.

Bilecen K, Fong JC, Cheng A, Jones CJ, Zamorano-Sánchez D, Yildiz FH.

Infect Immun. 2015 Mar;83(3):1199-209. doi: 10.1128/IAI.02700-14. Epub 2015 Jan 12.

21.

Molecular determinants of mechanical properties of V. cholerae biofilms at the air-liquid interface.

Hollenbeck EC, Fong JC, Lim JY, Yildiz FH, Fuller GG, Cegelski L.

Biophys J. 2014 Nov 18;107(10):2245-52. doi: 10.1016/j.bpj.2014.10.015.

22.

Ascertainment bias causes false signal of anticipation in genetic prion disease.

Minikel EV, Zerr I, Collins SJ, Ponto C, Boyd A, Klug G, Karch A, Kenny J, Collinge J, Takada LT, Forner S, Fong JC, Mead S, Geschwind MD.

Am J Hum Genet. 2014 Oct 2;95(4):371-82. doi: 10.1016/j.ajhg.2014.09.003.

23.

Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion.

Lee SE, Khazenzon AM, Trujillo AJ, Guo CC, Yokoyama JS, Sha SJ, Takada LT, Karydas AM, Block NR, Coppola G, Pribadi M, Geschwind DH, Rademakers R, Fong JC, Weiner MW, Boxer AL, Kramer JH, Rosen HJ, Miller BL, Seeley WW.

Brain. 2014 Nov;137(Pt 11):3047-60. doi: 10.1093/brain/awu248. Epub 2014 Oct 1.

24.

The Type II secretion system delivers matrix proteins for biofilm formation by Vibrio cholerae.

Johnson TL, Fong JC, Rule C, Rogers A, Yildiz FH, Sandkvist M.

J Bacteriol. 2014 Dec;196(24):4245-52. doi: 10.1128/JB.01944-14. Epub 2014 Sep 29.

25.

Vibrio cholerae use pili and flagella synergistically to effect motility switching and conditional surface attachment.

Utada AS, Bennett RR, Fong JCN, Gibiansky ML, Yildiz FH, Golestanian R, Wong GCL.

Nat Commun. 2014 Sep 19;5:4913. doi: 10.1038/ncomms5913.

26.

Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approach.

Reichhardt C, Fong JC, Yildiz F, Cegelski L.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt B):378-83. doi: 10.1016/j.bbamem.2014.05.030. Epub 2014 Jun 7.

27.

The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells.

Read ML, Seed RI, Fong JC, Modasia B, Ryan GA, Watkins RJ, Gagliano T, Smith VE, Stratford AL, Kwan PK, Sharma N, Dixon OM, Watkinson JC, Boelaert K, Franklyn JA, Turnell AS, McCabe CJ.

Endocrinology. 2014 Apr;155(4):1222-34. doi: 10.1210/en.2013-1646. Epub 2014 Feb 7.

28.

Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases.

Kim MO, Cali I, Oehler A, Fong JC, Wong K, See T, Katz JS, Gambetti P, Bettcher BM, Dearmond SJ, Geschwind MD.

Acta Neuropathol Commun. 2013 Dec 12;1:80. doi: 10.1186/2051-5960-1-80.

29.

Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.

Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV Jr, Moore MJ, Shaw CE, Gao FB.

PLoS One. 2013 Oct 15;8(10):e76055. doi: 10.1371/journal.pone.0076055. eCollection 2013.

30.

Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.

Lewy GD, Ryan GA, Read ML, Fong JC, Poole V, Seed RI, Sharma N, Smith VE, Kwan PP, Stewart SL, Bacon A, Warfield A, Franklyn JA, McCabe CJ, Boelaert K.

Endocrinology. 2013 Nov;154(11):4408-22. doi: 10.1210/en.2012-2156. Epub 2013 Jul 18.

PMID:
23867215
31.

Structural basis for biofilm formation via the Vibrio cholerae matrix protein RbmA.

Giglio KM, Fong JC, Yildiz FH, Sondermann H.

J Bacteriol. 2013 Jul;195(14):3277-86. doi: 10.1128/JB.00374-13. Epub 2013 May 17.

32.

Development of quinoline-based disruptors of biofilm formation against Vibrio cholerae.

León B, Fong JC, Peach KC, Wong WR, Yildiz FH, Linington RG.

Org Lett. 2013 Mar 15;15(6):1234-7. doi: 10.1021/ol400150z. Epub 2013 Mar 5.

PMID:
23461487
33.

Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutation.

Takada LT, Pimentel ML, Dejesus-Hernandez M, Fong JC, Yokoyama JS, Karydas A, Thibodeau MP, Rutherford NJ, Baker MC, Lomen-Hoerth C, Rademakers R, Miller BL.

Arch Neurol. 2012 Sep;69(9):1149-53. doi: 10.1001/archneurol.2012.650.

34.

Depletion of SUMO ligase hMMS21 impairs G1 to S transition in MCF-7 breast cancer cells.

Ni HJ, Chang YN, Kao PH, Chai SP, Hsieh YH, Wang DH, Fong JC.

Biochim Biophys Acta. 2012 Dec;1820(12):1893-900. doi: 10.1016/j.bbagen.2012.08.002. Epub 2012 Aug 10.

PMID:
22906975
35.

Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features.

Sha SJ, Takada LT, Rankin KP, Yokoyama JS, Rutherford NJ, Fong JC, Khan B, Karydas A, Baker MC, DeJesus-Hernandez M, Pribadi M, Coppola G, Geschwind DH, Rademakers R, Lee SE, Seeley W, Miller BL, Boxer AL.

Neurology. 2012 Sep 4;79(10):1002-11. doi: 10.1212/WNL.0b013e318268452e. Epub 2012 Aug 8.

36.

Genetic counseling for FTD/ALS caused by the C9ORF72 hexanucleotide expansion.

Fong JC, Karydas AM, Goldman JS.

Alzheimers Res Ther. 2012 Jul 19;4(4):27. doi: 10.1186/alzrt130. eCollection 2012. Review.

37.

Molecular architecture and assembly principles of Vibrio cholerae biofilms.

Berk V, Fong JC, Dempsey GT, Develioglu ON, Zhuang X, Liphardt J, Yildiz FH, Chu S.

Science. 2012 Jul 13;337(6091):236-9. doi: 10.1126/science.1222981.

38.

A 44-year-old man with profound behavioural changes.

Laforce R Jr, Kerchner GA, Rabinovici GD, Fong JC, Miller BL, Seeley WW, Grinberg LT.

Can J Neurol Sci. 2012 Jul;39(4):527-30. No abstract available.

39.

Subtle imaging findings in a case of tight filum terminale syndrome.

Yeung JT, Lee CM, Fong JC.

Hong Kong Med J. 2012 Jun;18(3):258-9. No abstract available.

40.

Cellular levels and binding of c-di-GMP control subcellular localization and activity of the Vibrio cholerae transcriptional regulator VpsT.

Shikuma NJ, Fong JC, Yildiz FH.

PLoS Pathog. 2012;8(5):e1002719. doi: 10.1371/journal.ppat.1002719. Epub 2012 May 24.

41.

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.

Smith VE, Read ML, Turnell AS, Sharma N, Lewy GD, Fong JC, Seed RI, Kwan P, Ryan G, Mehanna H, Chan SY, Darras VM, Boelaert K, Franklyn JA, McCabe CJ.

Endocrinology. 2012 Jul;153(7):3526-36. doi: 10.1210/en.2011-2030. Epub 2012 Apr 25.

PMID:
22535767
42.

Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion.

Khan BK, Yokoyama JS, Takada LT, Sha SJ, Rutherford NJ, Fong JC, Karydas AM, Wu T, Ketelle RS, Baker MC, Hernandez MD, Coppola G, Geschwind DH, Rademakers R, Lee SE, Rosen HJ, Rabinovici GD, Seeley WW, Rankin KP, Boxer AL, Miller BL.

J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):358-64. doi: 10.1136/jnnp-2011-301883.

43.

Synergistic induction of interleukin-6 expression by endothelin-1 and cyclic AMP in adipocytes.

Chai SP, Juan CC, Kao PH, Wang DH, Fong JC.

Int J Obes (Lond). 2013 Feb;37(2):197-203. doi: 10.1038/ijo.2012.11. Epub 2012 Jan 31.

PMID:
22290536
44.

Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment.

Read ML, Lewy GD, Fong JC, Sharma N, Seed RI, Smith VE, Gentilin E, Warfield A, Eggo MC, Knauf JA, Leadbeater WE, Watkinson JC, Franklyn JA, Boelaert K, McCabe CJ.

Cancer Res. 2011 Oct 1;71(19):6153-64. doi: 10.1158/0008-5472.CAN-11-0720. Epub 2011 Aug 15.

45.

A novel cross-talk between endothelin-1 and cyclic AMP signaling pathways in the regulation of GLUT1 transcription in 3T3-L1 adipocytes.

Kao YS, Fong JC.

Cell Signal. 2011 May;23(5):901-10. doi: 10.1016/j.cellsig.2011.01.016. Epub 2011 Jan 22.

PMID:
21262356
46.

Role of Vibrio polysaccharide (vps) genes in VPS production, biofilm formation and Vibrio cholerae pathogenesis.

Fong JC, Syed KA, Klose KE, Yildiz FH.

Microbiology. 2010 Sep;156(Pt 9):2757-69. doi: 10.1099/mic.0.040196-0. Epub 2010 May 13.

47.

Vibrio cholerae VpsT regulates matrix production and motility by directly sensing cyclic di-GMP.

Krasteva PV, Fong JC, Shikuma NJ, Beyhan S, Navarro MV, Yildiz FH, Sondermann H.

Science. 2010 Feb 12;327(5967):866-8. doi: 10.1126/science.1181185.

48.

Titanium versus autograft ossiculoplasty.

Fong JC, Michael P, Raut V.

Acta Otolaryngol. 2010 May;130(5):554-8. doi: 10.3109/00016480903338131.

PMID:
19958249
49.

A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer.

Smith VE, Read ML, Turnell AS, Watkins RJ, Watkinson JC, Lewy GD, Fong JC, James SR, Eggo MC, Boelaert K, Franklyn JA, McCabe CJ.

J Cell Sci. 2009 Sep 15;122(Pt 18):3393-402. doi: 10.1242/jcs.045427. Epub 2009 Aug 25.

50.

Overexpression of VpsS, a hybrid sensor kinase, enhances biofilm formation in Vibrio cholerae.

Shikuma NJ, Fong JC, Odell LS, Perchuk BS, Laub MT, Yildiz FH.

J Bacteriol. 2009 Aug;191(16):5147-58. doi: 10.1128/JB.00401-09. Epub 2009 Jun 12.

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