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Items: 43


Role for GrgA in Regulation of σ28-Dependent Transcription in the Obligate Intracellular Bacterial Pathogen Chlamydia trachomatis.

Desai M, Wurihan W, Di R, Fondell JD, Nickels BE, Bao X, Fan H.

J Bacteriol. 2018 Sep 24;200(20). pii: e00298-18. doi: 10.1128/JB.00298-18. Print 2018 Oct 15.


Identification of a strong and specific antichlamydial N-acylhydrazone.

Zhang H, Kunadia A, Lin Y, Fondell JD, Seidel D, Fan H.

PLoS One. 2017 Oct 3;12(10):e0185783. doi: 10.1371/journal.pone.0185783. eCollection 2017.


ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity.

Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD.

Mol Cancer Res. 2013 Jul;11(7):736-47. doi: 10.1158/1541-7786.MCR-12-0618. Epub 2013 Mar 28.


The Mediator complex in thyroid hormone receptor action.

Fondell JD.

Biochim Biophys Acta. 2013 Jul;1830(7):3867-75. doi: 10.1016/j.bbagen.2012.02.012. Epub 2012 Feb 28. Review.


Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif.

Jin F, Claessens F, Fondell JD.

J Biol Chem. 2012 Jan 6;287(2):858-70. doi: 10.1074/jbc.M111.304519. Epub 2011 Nov 18.


Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.

Tong X, Gui H, Jin F, Heck BW, Lin P, Ma J, Fondell JD, Tsai CC.

EMBO Rep. 2011 May;12(5):428-35. doi: 10.1038/embor.2011.49. Epub 2011 Apr 8.


Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events.

Belakavadi M, Dell J, Grover GJ, Fondell JD.

Mol Cell Endocrinol. 2011 Jun 6;339(1-2):72-80. doi: 10.1016/j.mce.2011.03.016. Epub 2011 Mar 31.


PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex.

Pyper SR, Viswakarma N, Jia Y, Zhu YJ, Fondell JD, Reddy JK.

PPAR Res. 2010;2010. pii: 173907. doi: 10.1155/2010/173907. Epub 2010 Sep 5.


Repression of cardiac phospholamban gene expression is mediated by thyroid hormone receptor-{alpha}1 and involves targeted covalent histone modifications.

Belakavadi M, Saunders J, Weisleder N, Raghava PS, Fondell JD.

Endocrinology. 2010 Jun;151(6):2946-56. doi: 10.1210/en.2009-1241. Epub 2010 Apr 14.


Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation.

Belakavadi M, Fondell JD.

Mol Cell Biol. 2010 May;30(10):2437-48. doi: 10.1128/MCB.01541-09. Epub 2010 Mar 15.


A novel androgen receptor-binding element modulates Cdc6 transcription in prostate cancer cells during cell-cycle progression.

Jin F, Fondell JD.

Nucleic Acids Res. 2009 Aug;37(14):4826-38. doi: 10.1093/nar/gkp510. Epub 2009 Jun 11.


MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling.

Belakavadi M, Pandey PK, Vijayvargia R, Fondell JD.

Mol Cell Biol. 2008 Jun;28(12):3932-42. doi: 10.1128/MCB.02191-07. Epub 2008 Apr 7.


Role of the mediator complex in nuclear hormone receptor signaling.

Belakavadi M, Fondell JD.

Rev Physiol Biochem Pharmacol. 2006;156:23-43. Review.


Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1.

Udayakumar TS, Belakavadi M, Choi KH, Pandey PK, Fondell JD.

J Biol Chem. 2006 May 26;281(21):14691-9. Epub 2006 Mar 30.


Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation.

Pandey PK, Udayakumar TS, Lin X, Sharma D, Shapiro PS, Fondell JD.

Mol Cell Biol. 2005 Dec;25(24):10695-710.


Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation.

Liu Y, Xia X, Fondell JD, Yen PM.

Mol Endocrinol. 2006 Mar;20(3):483-90. Epub 2005 Oct 27.


Nuclear receptor recruitment of histone-modifying enzymes to target gene promoters.

Tsai CC, Fondell JD.

Vitam Horm. 2004;68:93-122. Review.


A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch AG, Holmberg S, Holstege FC, Jaehning JA, Kim YJ, Kuras L, Leutz A, Lis JT, Meisterernest M, Naar AM, Nasmyth K, Parvin JD, Ptashne M, Reinberg D, Ronne H, Sadowski I, Sakurai H, Sipiczki M, Sternberg PW, Stillman DJ, Strich R, Struhl K, Svejstrup JQ, Tuck S, Winston F, Roeder RG, Kornberg RD.

Mol Cell. 2004 Jun 4;14(5):553-7. No abstract available.


Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.

Wang Q, Udayakumar TS, Vasaitis TS, Brodie AM, Fondell JD.

J Biol Chem. 2004 Apr 23;279(17):17319-28. Epub 2004 Feb 13.


Effects of total glycosides from Baishouwu on human breast and prostate cancer cell proliferation.

Wang H, Wang Q, Srivastava RK, Gong SS, Lao L, Fondell JD, Wang JB.

Altern Ther Health Med. 2003 Sep-Oct;9(5):62-6.


Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.

Yoon HG, Chan DW, Huang ZQ, Li J, Fondell JD, Qin J, Wong J.

EMBO J. 2003 Mar 17;22(6):1336-46.


A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

Wang Q, Sharma D, Ren Y, Fondell JD.

J Biol Chem. 2002 Nov 8;277(45):42852-8. Epub 2002 Sep 5.


Conditional over-expression of estrogen receptor alpha in a transgenic mouse model.

Hruska KS, Tilli MT, Ren S, Cotarla I, Kwong T, Li M, Fondell JD, Hewitt JA, Koos RD, Furth PA, Flaws JA.

Transgenic Res. 2002 Aug;11(4):361-72.


Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1.

Zhang Y, Fondell JD, Wang Q, Xia X, Cheng A, Lu ML, Hamburger AW.

Oncogene. 2002 Aug 15;21(36):5609-18.


Gene activation by thyroid hormone receptor in vitro and purification of the TRAP coactivator complex.

Fondell JD.

Methods Mol Biol. 2002;202:195-214. Review. No abstract available.


Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo.

Sharma D, Fondell JD.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7934-9. Epub 2002 May 28.


Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells.

Sharma D, Fondell JD.

Mol Endocrinol. 2000 Dec;14(12):2001-9.


Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors.

Ren Y, Behre E, Ren Z, Zhang J, Wang Q, Fondell JD.

Mol Cell Biol. 2000 Aug;20(15):5433-46.


Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J, Roeder RG.

Mol Cell. 1999 Mar;3(3):361-70.


A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.

Gu W, Malik S, Ito M, Yuan CX, Fondell JD, Zhang X, Martinez E, Qin J, Roeder RG.

Mol Cell. 1999 Jan;3(1):97-108. Erratum in: Mol Cell 1999 Apr;3(4):following 541.


The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.

Yuan CX, Ito M, Fondell JD, Fu ZY, Roeder RG.

Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7939-44. Erratum in: Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14584.


Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

Fondell JD, Ge H, Roeder RG.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8329-33.


Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression.

Fondell JD, Brunel F, Hisatake K, Roeder RG.

Mol Cell Biol. 1996 Jan;16(1):281-7.


Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta.

Sauer F, Fondell JD, Ohkuma Y, Roeder RG, Jäckle H.

Nature. 1995 May 11;375(6527):162-4.


The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.

Marolleau JP, Fondell JD, Malissen M, Trucy J, Barbier E, Marcu KB, Cazenave PA, Primi D.

Cell. 1988 Oct 21;55(2):291-300.


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