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Items: 13

1.

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, Frohberger SJ, Sjoberg H, Pionnier N, Murphy E, Archer J, Steven A, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Kwenti TDB, Woods AK, Joseph SB, Hull MV, Xiong W, Kuhen KL, Taylor MJ, Wanji S, Turner JD, Hübner MP, Hoerauf A, Chatterjee AK, Roland J, Tremblay MS, Schultz PG, Sullivan W, Chu XJ, Petrassi HM, McNamara CW.

Sci Transl Med. 2019 May 8;11(491). pii: eaav3523. doi: 10.1126/scitranslmed.aav3523.

PMID:
31068442
2.

Mouse models of Loa loa.

Pionnier NP, Sjoberg H, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Tayong DB, Taylor MJ, Wanji S, Turner JD.

Nat Commun. 2019 Mar 29;10(1):1429. doi: 10.1038/s41467-019-09442-0.

3.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau2086. doi: 10.1126/scitranslmed.aau2086.

PMID:
30867321
4.

Mapping of lymphatic filariasis in loiasis areas: A new strategy shows no evidence for Wuchereria bancrofti endemicity in Cameroon.

Wanji S, Esum ME, Njouendou AJ, Mbeng AA, Chounna Ndongmo PW, Abong RA, Fru J, Fombad FF, Nchanji GT, Ngongeh G, Ngandjui NV, Enyong PI, Storey H, Curtis KC, Fischer K, Fauver JR, Lew D, Goss CW, Fischer PU.

PLoS Negl Trop Dis. 2019 Mar 8;13(3):e0007192. doi: 10.1371/journal.pntd.0007192. eCollection 2019 Mar.

5.

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.

Sjoberg HT, Pionnier N, Aljayyoussi G, Metuge HM, Njouendou AJ, Chunda VC, Fombad FF, Tayong DB, Gandjui NVT, Akumtoh DN, Chounna PWN, Ndzeshang BL, Lachaud S, Tekle F, Quirynen L, Engelen M, Baeten B, Steven A, Ward SA, Taylor MJ, Wanji S, Turner JD.

PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0006356. doi: 10.1371/journal.pntd.0006356. eCollection 2019 Jan.

6.

Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents.

Fombad FF, Njouendou AJ, Ndongmo PC, Ritter M, Chunda VC, Metuge HM, Gandjui NVT, Enyong P, Njiokou F, Hoerauf A, Mackenzie CD, Wanji S.

Parasit Vectors. 2019 Jan 8;12(1):14. doi: 10.1186/s13071-018-3282-x.

7.

Impact of repeated annual community directed treatment with ivermectin on loiasis parasitological indicators in Cameroon: Implications for onchocerciasis and lymphatic filariasis elimination in areas co-endemic with Loa loa in Africa.

Wanji S, Chounna Ndongmo WP, Fombad FF, Kengne-Ouafo JA, Njouendou AJ, Longang Tchounkeu YF, Koudou B, Bockarie M, Fobi G, Roungou JB, Enyong PA.

PLoS Negl Trop Dis. 2018 Sep 18;12(9):e0006750. doi: 10.1371/journal.pntd.0006750. eCollection 2018 Sep.

8.

Evaluation of in vitro culture systems for the maintenance of microfilariae and infective larvae of Loa loa.

Zofou D, Fombad FF, Gandjui NVT, Njouendou AJ, Kengne-Ouafo AJ, Chounna Ndongmo PW, Datchoua-Poutcheu FR, Enyong PA, Bita DT, Taylor MJ, Turner JD, Wanji S.

Parasit Vectors. 2018 May 2;11(1):275. doi: 10.1186/s13071-018-2852-2.

9.

Heterogeneity in the in vitro susceptibility of Loa loa microfilariae to drugs commonly used in parasitological infections.

Njouendou AJ, Fombad FF, O'Neill M, Zofou D, Nutting C, Ndongmo PC, Kengne-Ouafo AJ, Geary TG, Mackenzie CD, Wanji S.

Parasit Vectors. 2018 Apr 4;11(1):223. doi: 10.1186/s13071-018-2799-3.

10.

Successful long-term maintenance of Mansonella perstans in an in vitro culture system.

Njouendou AJ, Ritter M, Ndongmo WPC, Kien CA, Narcisse GTV, Fombad FF, Tayong DB, Pfarr K, Layland LE, Hoerauf A, Wanji S.

Parasit Vectors. 2017 Nov 10;10(1):563. doi: 10.1186/s13071-017-2515-8.

11.

Update on the distribution of Mansonella perstans in the southern part of Cameroon: influence of ecological factors and mass drug administration with ivermectin.

Wanji S, Tayong DB, Layland LE, Datchoua Poutcheu FR, Ndongmo WP, Kengne-Ouafo JA, Ritter M, Amvongo-Adjia N, Fombad FF, Njeshi CN, Nkwescheu AS, Enyong PA, Hoerauf A.

Parasit Vectors. 2016 May 31;9(1):311. doi: 10.1186/s13071-016-1595-1.

12.

Further evidence of the cross-reactivity of the Binax NOW® Filariasis ICT cards to non-Wuchereria bancrofti filariae: experimental studies with Loa loa and Onchocerca ochengi.

Wanji S, Amvongo-Adjia N, Njouendou AJ, Kengne-Ouafo JA, Ndongmo WP, Fombad FF, Koudou B, Enyong PA, Bockarie M.

Parasit Vectors. 2016 May 5;9:267. doi: 10.1186/s13071-016-1556-8.

13.

Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region.

Wanji S, Amvongo-Adjia N, Koudou B, Njouendou AJ, Chounna Ndongmo PW, Kengne-Ouafo JA, Datchoua-Poutcheu FR, Fovennso BA, Tayong DB, Fombad FF, Fischer PU, Enyong PI, Bockarie M.

PLoS Negl Trop Dis. 2015 Nov 6;9(11):e0004184. doi: 10.1371/journal.pntd.0004184. eCollection 2015 Nov.

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