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Items: 31


Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists.

Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, Schneekloth JS, Merkel J, Teran C, Naderi ZK, Supattapone S, Strittmatter SM.

Cell Rep. 2019 Jan 29;26(5):1368. doi: 10.1016/j.celrep.2019.01.064. No abstract available.


Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists.

Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, Schneekloth JS, Merkel J, Teran C, Naderi ZK, Supattapone S, Strittmatter SM.

Cell Rep. 2019 Jan 2;26(1):145-158.e8. doi: 10.1016/j.celrep.2018.12.021. Erratum in: Cell Rep. 2019 Jan 29;26(5):1368.


Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins.

Wexler AG, Schofield WB, Degnan PH, Folta-Stogniew E, Barry NA, Goodman AL.

Elife. 2018 Sep 18;7. pii: e37138. doi: 10.7554/eLife.37138.


Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.

Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC.

Nat Commun. 2016 Nov 21;7:13516. doi: 10.1038/ncomms13516.


Homodimerization enhances both sensitivity and dynamic range of the ligand-binding domain of type 1 metabotropic glutamate receptor.

Serebryany E, Folta-Stogniew E, Liu J, Yan EC.

FEBS Lett. 2016 Dec;590(23):4308-4317. doi: 10.1002/1873-3468.12473. Epub 2016 Nov 19.


ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy.

Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT.

Nat Commun. 2015 Dec 1;6:10006. doi: 10.1038/ncomms10006.


Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK.

Murray PB, Lax I, Reshetnyak A, Ligon GF, Lillquist JS, Natoli EJ Jr, Shi X, Folta-Stogniew E, Gunel M, Alvarado D, Schlessinger J.

Sci Signal. 2015 Jan 20;8(360):ra6. doi: 10.1126/scisignal.2005916.


Antigenic requirement for Gag in a vaccine that protects against high-dose mucosal challenge with simian immunodeficiency virus.

Schell JB, Bahl K, Folta-Stogniew E, Rose N, Buonocore L, Marx PA, Gambhira R, Rose JK.

Virology. 2015 Feb;476:405-412. doi: 10.1016/j.virol.2014.12.027. Epub 2015 Jan 12.


The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer.

Reshetnyak AV, Opatowsky Y, Boggon TJ, Folta-Stogniew E, Tome F, Lax I, Schlessinger J.

Mol Cell. 2015 Jan 8;57(1):191-201. doi: 10.1016/j.molcel.2014.11.021. Epub 2014 Dec 24.


Oligomerization and higher-order assembly contribute to sub-cellular localization of a bacterial scaffold.

Bowman GR, Perez AM, Ptacin JL, Ighodaro E, Folta-Stogniew E, Comolli LR, Shapiro L.

Mol Microbiol. 2013 Nov;90(4):776-95. doi: 10.1111/mmi.12398. Epub 2013 Oct 7.


Recognition of the F&H motif by the Lowe syndrome protein OCRL.

Pirruccello M, Swan LE, Folta-Stogniew E, De Camilli P.

Nat Struct Mol Biol. 2011 Jun 12;18(7):789-95. doi: 10.1038/nsmb.2071.


Molecular recognition of leucine-aspartate repeat (LD) motifs by the focal adhesion targeting homology domain of cerebral cavernous malformation 3 (CCM3).

Li X, Ji W, Zhang R, Folta-Stogniew E, Min W, Boggon TJ.

J Biol Chem. 2011 Jul 22;286(29):26138-47. doi: 10.1074/jbc.M110.211250. Epub 2011 Jun 1.


Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1.

Kapoor N, Gupta R, Menon ST, Folta-Stogniew E, Raleigh DP, Sakmar TP.

J Biol Chem. 2010 Oct 8;285(41):31647-60. doi: 10.1074/jbc.M110.148429. Epub 2010 Aug 2.


Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR.

Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT.

Biochemistry. 2010 Jun 8;49(22):4620-34. doi: 10.1021/bi9021445.


Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site.

Hoopes JT, Liu X, Xu X, Demeler B, Folta-Stogniew E, Li C, Ha Y.

J Biol Chem. 2010 Jan 15;285(3):2165-73. doi: 10.1074/jbc.M109.018432. Epub 2009 Nov 10.


Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.

Casuscelli J, Schmidt S, DeGray B, Petri ET, Celić A, Folta-Stogniew E, Ehrlich BE, Boggon TJ.

Am J Physiol Renal Physiol. 2009 Nov;297(5):F1310-5. doi: 10.1152/ajprenal.00412.2009. Epub 2009 Sep 2.


Reexamination of the role of the amino terminus of SecA in promoting its dimerization and functional state.

Das S, Stivison E, Folta-Stogniew E, Oliver D.

J Bacteriol. 2008 Nov;190(21):7302-7. doi: 10.1128/JB.00593-08. Epub 2008 Aug 22.


Keck Foundation Biotechnology Resource Laboratory, Yale University.

Stone KL, Bjornson RD, Blasko GG, Bruce C, Cofrancesco R, Carriero NJ, Colangelo CM, Crawford JK, Crawford JM, daSilva NC, Deluca JD, Elliott JI, Elliott MM, Flory PJ, Folta-Stogniew EJ, Gulcicek E, Kong Y, Lam TT, Lee JY, Lin A, LoPresti MB, Mane SM, McMurray WJ, Tikhonova IR, Westman S, Williams NA, Wu TL, Hongyu Z, Williams KR.

Yale J Biol Med. 2007 Dec;80(4):195-211. Review. No abstract available.


Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.

Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D.

EMBO J. 2008 Jan 9;27(1):277-89. Epub 2007 Dec 6.


The structural basis of cyclic diguanylate signal transduction by PilZ domains.

Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF.

EMBO J. 2007 Dec 12;26(24):5153-66. Epub 2007 Nov 22.


Exchange of DNA base pairs that coincides with recognition of homology promoted by E. coli RecA protein.

Folta-Stogniew E, O'Malley S, Gupta R, Anderson KS, Radding CM.

Mol Cell. 2004 Sep 24;15(6):965-75.


Trimeric subunit stoichiometry of the glutamate transporters from Bacillus caldotenax and Bacillus stearothermophilus.

Yernool D, Boudker O, Folta-Stogniew E, Gouaux E.

Biochemistry. 2003 Nov 11;42(44):12981-8.


Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein.

Gupta RC, Folta-Stogniew E, O'Malley S, Takahashi M, Radding CM.

Mol Cell. 1999 Nov;4(5):705-14.


Human Rad51 protein can form homologous joints in the absence of net strand exchange.

Gupta RC, Folta-Stogniew E, Radding CM.

J Biol Chem. 1999 Jan 15;274(3):1248-56.


RecA tests homology at both pairing and strand exchange.

Bazemore LR, Folta-Stogniew E, Takahashi M, Radding CM.

Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11863-8.


Base-catalysis of imino proton exchange in DNA: effects of catalyst upon DNA structure and dynamics.

Folta-Stogniew E, Russu IM.

Biochemistry. 1996 Jun 25;35(25):8439-49.


Energetics of base pair opening in a DNA dodecamer containing an A3T3 tract.

Moe JG, Folta-Stogniew E, Russu IM.

Nucleic Acids Res. 1995 Jun 11;23(11):1984-9.


Sequence dependence of base-pair opening in a DNA dodecamer containing the CACA/GTGT sequence motif.

Folta-Stogniew E, Russu IM.

Biochemistry. 1994 Sep 13;33(36):11016-24.


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