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Items: 8


Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease.

Felmlee MA, Jones RS, Rodriguez-Cruz V, Follman KE, Morris ME.

Pharmacol Rev. 2020 Apr;72(2):466-485. doi: 10.1124/pr.119.018762. Review.


Treatment of γ-Hydroxybutyric Acid and γ-Butyrolactone Overdose with Two Potent Monocarboxylate Transporter 1 Inhibitors, AZD3965 and AR-C155858.

Follman KE, Morris ME.

J Pharmacol Exp Ther. 2019 Jul;370(1):84-91. doi: 10.1124/jpet.119.256503. Epub 2019 Apr 22.


Simulation-Based Analysis of the Impact of Renal Impairment on the Pharmacokinetics of Highly Metabolized Compounds.

Follman KE, Morris ME.

Pharmaceutics. 2019 Mar 2;11(3). pii: E105. doi: 10.3390/pharmaceutics11030105.


Effects of renal impairment on transporter-mediated renal reabsorption of drugs and renal drug-drug interactions: A simulation-based study.

Follman KE, Dave RA, Morris ME.

Biopharm Drug Dispos. 2018 Apr;39(4):218-231. doi: 10.1002/bdd.2128.


Prediction of the Effects of Renal Impairment on Clearance for Organic Cation Drugs that Undergo Renal Secretion: A Simulation-Based Study.

Follman KE, Morris ME.

Drug Metab Dispos. 2018 May;46(5):758-769. doi: 10.1124/dmd.117.079558. Epub 2018 Feb 28.


The Drug of Abuse Gamma-Hydroxybutyric Acid Exhibits Tissue-Specific Nonlinear Distribution.

Felmlee MA, Morse BL, Follman KE, Morris ME.

AAPS J. 2017 Dec 26;20(1):21. doi: 10.1208/s12248-017-0180-7.


Effect of chronic γ-hydroxybutyrate (GHB) administration on GHB toxicokinetics and GHB-induced respiratory depression.

Morse BL, Chadha GS, Felmlee MA, Follman KE, Morris ME.

Am J Drug Alcohol Abuse. 2017 Nov;43(6):686-693. doi: 10.1080/00952990.2017.1339055. Epub 2017 Jun 29.


γ-Hydroxybutyric Acid (GHB) Pharmacokinetics and Pharmacodynamics: Semi-Mechanistic and Physiologically Relevant PK/PD Model.

Dave RA, Follman KE, Morris ME.

AAPS J. 2017 Sep;19(5):1449-1460. doi: 10.1208/s12248-017-0111-7. Epub 2017 Jun 26.

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