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Items: 1 to 50 of 111

1.

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes.

Lebreton F, Lavallard V, Bellofatto K, Bonnet R, Wassmer CH, Perez L, Kalandadze V, Follenzi A, Boulvain M, Kerr-Conte J, Goodman DJ, Bosco D, Berney T, Berishvili E.

Nat Commun. 2019 Oct 3;10(1):4491. doi: 10.1038/s41467-019-12472-3.

2.

Biological and clinical implications of BIRC3 mutations in chronic lymphocytic leukemia.

Diop F, Moia R, Favini C, Spaccarotella E, De Paoli L, Bruscaggin A, Spina V, Terzi-di-Bergamo L, Arruga F, Tarantelli C, Deambrogi C, Rasi S, Adhinaveni R, Patriarca A, Favini S, Sagiraju S, Jabangwe C, Kodipad AA, Peroni D, Mauro FR, Del Giudice I, Forconi F, Cortelezzi A, Zaja F, Bomben R, Rossi FM, Visco C, Chiarenza A, Rigolin GM, Marasca R, Coscia M, Perbellini O, Tedeschi A, Laurenti L, Motta M, Donaldson D, Weir P, Mills K, Thornton P, Lawless S, Bertoni F, Del Poeta G, Cuneo A, Follenzi A, Gattei V, Boldorini RL, Catherwood M, Deaglio S, Foá R, Gaidano G, Rossi D.

Haematologica. 2019 Aug 1. pii: haematol.2019.219550. doi: 10.3324/haematol.2019.219550. [Epub ahead of print]

3.

Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts.

Pignani S, Zappaterra F, Barbon E, Follenzi A, Bovolenta M, Bernardi F, Branchini A, Pinotti M.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun;1862(6):619-624. doi: 10.1016/j.bbagrm.2019.04.002. Epub 2019 Apr 18.

PMID:
31005673
4.

FVIII expression by its native promoter sustains long-term correction avoiding immune response in hemophilic mice.

Merlin S, Famà R, Borroni E, Zanolini D, Bruscaggin V, Zucchelli S, Follenzi A.

Blood Adv. 2019 Mar 12;3(5):825-838. doi: 10.1182/bloodadvances.2018027979.

5.

Transcriptional Targeting and MicroRNA Regulation of Lentiviral Vectors.

Merlin S, Follenzi A.

Mol Ther Methods Clin Dev. 2019 Jan 8;12:223-232. doi: 10.1016/j.omtm.2018.12.013. eCollection 2019 Mar 15. Review.

6.

Author Correction: Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy.

Aspesi A, Monteleone V, Betti M, Actis C, Morleo G, Sculco M, Guarrera S, Wlodarski MW, Ramenghi U, Santoro C, Ellis SR, Loreni F, Follenzi A, Dianzani I.

Sci Rep. 2018 Nov 16;8(1):17227. doi: 10.1038/s41598-018-35522-0.

7.

Patient-Specific iPSC-Derived Endothelial Cells Provide Long-Term Phenotypic Correction of Hemophilia A.

Olgasi C, Talmon M, Merlin S, Cucci A, Richaud-Patin Y, Ranaldo G, Colangelo D, Di Scipio F, Berta GN, Borsotti C, Valeri F, Faraldi F, Prat M, Messina M, Schinco P, Lombardo A, Raya A, Follenzi A.

Stem Cell Reports. 2018 Dec 11;11(6):1391-1406. doi: 10.1016/j.stemcr.2018.10.012. Epub 2018 Nov 8.

8.

Emerging Therapeutic Approaches for Diamond Blackfan Anemia.

Aspesi A, Borsotti C, Follenzi A.

Curr Gene Ther. 2018;18(6):327-335. doi: 10.2174/1566523218666181109124538. Review.

9.

New technologies in gene therapy for inducing immune tolerance in hemophilia A.

Borsotti C, Follenzi A.

Expert Rev Clin Immunol. 2018 Dec;14(12):1013-1019. doi: 10.1080/1744666X.2018.1539667. Epub 2018 Nov 3. Review.

PMID:
30345839
10.

In Atp7b-/- Mice Modeling Wilson's Disease Liver Repopulation With Bone Marrow-Derived Myofibroblasts or Inflammatory Cells and Not Hepatocytes Is Deleterious.

Sharma Y, Liu J, Kristian KE, Follenzi A, Gupta S.

Gene Expr. 2018 Dec 14;19(1):15-24. doi: 10.3727/105221618X15320123457380. Epub 2018 Jul 20.

11.

PPARs are mediators of anti-cancer properties of superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with conjugated linoleic acid.

Ricci M, Miola M, Multari C, Borroni E, Canuto RA, Congiusta N, Vernè E, Follenzi A, Muzio G.

Chem Biol Interact. 2018 Aug 25;292:9-14. doi: 10.1016/j.cbi.2018.07.003. Epub 2018 Jul 3.

PMID:
29986832
12.

A functional assay for the clinical annotation of genetic variants of uncertain significance in Diamond-Blackfan anemia.

Aspesi A, Betti M, Sculco M, Actis C, Olgasi C, Wlodarski MW, Vlachos A, Lipton JM, Ramenghi U, Santoro C, Follenzi A, Ellis SR, Dianzani I.

Hum Mutat. 2018 Aug;39(8):1102-1111. doi: 10.1002/humu.23551. Epub 2018 May 28.

13.

Fetuin B links vitamin D deficiency and pediatric obesity: Direct negative regulation by vitamin D.

Walker GE, Follenzi A, Bruscaggin V, Manfredi M, Bellone S, Marengo E, Maiuri L, Prodam F, Bona G.

J Steroid Biochem Mol Biol. 2018 Sep;182:37-49. doi: 10.1016/j.jsbmb.2018.04.009. Epub 2018 Apr 21.

14.

Corrigendum to "Innovative superparamagnetic iron-oxide nanoparticles coated with silica and conjugated with linoleic acid: Effect on tumor cell growth and viability" [Mater. Sci. Eng. C 76 (2017) 439-447].

Muzio G, Miola M, Ferraris S, Maggiora M, Bertone E, Puccinelli MP, Ricci M, Borroni E, Canuto RA, Verné E, Follenzi A.

Mater Sci Eng C Mater Biol Appl. 2018 May 1;86:198. doi: 10.1016/j.msec.2017.12.027. Epub 2018 Feb 3. No abstract available.

PMID:
29525093
15.

A humanized mouse model of liver fibrosis following expansion of transplanted hepatic stellate cells.

Benten D, Kluwe J, Wirth JW, Thiele ND, Follenzi A, Bhargava KK, Palestro CJ, Koepke M, Tjandra R, Volz T, Lutgehetmann M, Gupta S.

Lab Invest. 2018 Apr;98(4):525-536. doi: 10.1038/s41374-017-0010-7. Epub 2018 Jan 19.

16.

Endothelial MMP-9 drives the inflammatory response in abdominal aortic aneurysm (AAA).

Ramella M, Boccafoschi F, Bellofatto K, Follenzi A, Fusaro L, Boldorini R, Casella F, Porta C, Settembrini P, Cannas M.

Am J Transl Res. 2017 Dec 15;9(12):5485-5495. eCollection 2017.

17.

Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy.

Aspesi A, Monteleone V, Betti M, Actis C, Morleo G, Sculco M, Guarrera S, Wlodarski MW, Ramenghi U, Santoro C, Ellis SR, Loreni F, Follenzi A, Dianzani I.

Sci Rep. 2017 Sep 20;7(1):12010. doi: 10.1038/s41598-017-12307-5. Erratum in: Sci Rep. 2018 Nov 16;8(1):17227.

18.

Advanced cell-based modeling of the royal disease: characterization of the mutated F9 mRNA.

Martorell L, Luce E, Vazquez JL, Richaud-Patin Y, Jimenez-Delgado S, Corrales I, Borras N, Casacuberta-Serra S, Weber A, Parra R, Altisent C, Follenzi A, Dubart-Kupperschmitt A, Raya A, Vidal F, Barquinero J.

J Thromb Haemost. 2017 Nov;15(11):2188-2197. doi: 10.1111/jth.13808. Epub 2017 Sep 25.

PMID:
28834196
19.

Oxidative and ER stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury.

Imarisio C, Alchera E, Bangalore Revanna C, Valente G, Follenzi A, Trisolini E, Boldorini R, Carini R.

Free Radic Biol Med. 2017 Nov;112:141-148. doi: 10.1016/j.freeradbiomed.2017.07.020. Epub 2017 Jul 21.

PMID:
28739531
20.

Tumor targeting by lentiviral vectors combined with magnetic nanoparticles in mice.

Borroni E, Miola M, Ferraris S, Ricci G, Žužek Rožman K, Kostevšek N, Catizone A, Rimondini L, Prat M, Verné E, Follenzi A.

Acta Biomater. 2017 Sep 1;59:303-316. doi: 10.1016/j.actbio.2017.07.007. Epub 2017 Jul 5.

PMID:
28688987
21.

A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice.

Merlin S, Cannizzo ES, Borroni E, Bruscaggin V, Schinco P, Tulalamba W, Chuah MK, Arruda VR, VandenDriessche T, Prat M, Valente G, Follenzi A.

Mol Ther. 2017 Aug 2;25(8):1815-1830. doi: 10.1016/j.ymthe.2017.04.029. Epub 2017 May 26.

22.

Innovative superparamagnetic iron-oxide nanoparticles coated with silica and conjugated with linoleic acid: Effect on tumor cell growth and viability.

Muzio G, Miola M, Ferraris S, Maggiora M, Bertone E, Puccinelli MP, Ricci M, Borroni E, Canuto RA, Verné E, Follenzi A.

Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:439-447. doi: 10.1016/j.msec.2017.03.063. Epub 2017 Mar 10. Erratum in: Mater Sci Eng C Mater Biol Appl. 2018 May 1;86:198.

23.

A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis.

Angioni MM, Bellofatto K, Merlin S, Menegon S, Perra A, Petrelli A, Sulas P, Giordano S, Columbano A, Follenzi A.

Oncotarget. 2017 Feb 28;8(9):15716-15731. doi: 10.18632/oncotarget.14984.

24.

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ.

Blood. 2017 Mar 16;129(11):1514-1526. doi: 10.1182/blood-2016-09-742387. Epub 2017 Feb 1. Erratum in: Blood. 2017 Dec 21;130(25):2809.

25.

Evidence for CD19B-CD8T cell interactions in blood and tissues from patients with GvHD.

Deola S, Cugno C, Comoli P, Guido I, Rubert L, Zecca M, Zanolini D, Follenzi A, Langes M, Negri G, Tauber M, Pusceddu I, Cavattoni I, Svaldi M, Grigoleit GU, Baumeister E, Wang E, Rutella S, Marincola FM.

Bone Marrow Transplant. 2017 Mar;52(3):459-462. doi: 10.1038/bmt.2016.294. Epub 2016 Nov 7. No abstract available.

26.

Lentiviral vector interactions with the host cell.

Borsotti C, Borroni E, Follenzi A.

Curr Opin Virol. 2016 Dec;21:102-108. doi: 10.1016/j.coviro.2016.08.016. Epub 2016 Sep 13. Review.

PMID:
27637073
27.

Genetically modified human CD4(+) T cells can be evaluated in vivo without lethal graft-versus-host disease.

Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP.

Immunology. 2016 Aug;148(4):339-51. doi: 10.1111/imm.12613.

28.

Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy.

Merlin S, Bhargava KK, Ranaldo G, Zanolini D, Palestro CJ, Santambrogio L, Prat M, Follenzi A, Gupta S.

Am J Pathol. 2016 Mar;186(3):539-51. doi: 10.1016/j.ajpath.2015.11.002. Epub 2016 Jan 7.

29.

The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity.

Clement CC, Becerra A, Yin L, Zolla V, Huang L, Merlin S, Follenzi A, Shaffer SA, Stern LJ, Santambrogio L.

J Biol Chem. 2016 Mar 11;291(11):5576-95. doi: 10.1074/jbc.M115.655738. Epub 2016 Jan 6.

30.

Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.

Chen H, Choesang T, Li H, Sun S, Pham P, Bao W, Feola M, Westerman M, Li G, Follenzi A, Blanc L, Rivella S, Fleming RE, Ginzburg YZ.

Haematologica. 2016 Mar;101(3):297-308. doi: 10.3324/haematol.2015.127902. Epub 2015 Dec 3.

31.

The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice.

Rolla S, Alchera E, Imarisio C, Bardina V, Valente G, Cappello P, Mombello C, Follenzi A, Novelli F, Carini R.

Clin Sci (Lond). 2016 Feb;130(3):193-203. doi: 10.1042/CS20150405. Epub 2015 Nov 11.

PMID:
26558403
32.

Pharmacological Preconditioning by Adenosine A2a Receptor Stimulation: Features of the Protected Liver Cell Phenotype.

Alchera E, Imarisio C, Mandili G, Merlin S, Chandrashekar BR, Novelli F, Follenzi A, Carini R.

Biomed Res Int. 2015;2015:286746. doi: 10.1155/2015/286746. Epub 2015 Oct 11. Review.

33.

Correction: Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential.

Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, Merlin S, Talmon M, Novelli E, Diena M, Nicoletti C, Musarò A, Filigheddu N, Follenzi A, Prat M.

PLoS One. 2015 Oct 23;10(10):e0141632. doi: 10.1371/journal.pone.0141632. eCollection 2015. No abstract available.

34.

Erratum to: Switching of mesodermal and endodermal properties in hTERT-modified and expanded fetal human pancreatic progenitor cells.

Cheng K, Follenzi A, Surana M, Fleischer N, Gupta S.

Stem Cell Res Ther. 2015 Sep 30;6:189. doi: 10.1186/s13287-015-0176-0. No abstract available.

35.

Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks.

Canals I, Soriano J, Orlandi JG, Torrent R, Richaud-Patin Y, Jiménez-Delgado S, Merlin S, Follenzi A, Consiglio A, Vilageliu L, Grinberg D, Raya A.

Stem Cell Reports. 2015 Oct 13;5(4):546-57. doi: 10.1016/j.stemcr.2015.08.016. Epub 2015 Sep 24.

36.

Human Lipoaspirate as Autologous Injectable Active Scaffold for One-Step Repair of Cartilage Defects.

Bosetti M, Borrone A, Follenzi A, Messaggio F, Tremolada C, Cannas M.

Cell Transplant. 2016;25(6):1043-56. doi: 10.3727/096368915X689514. Epub 2015 Sep 21.

PMID:
26395761
37.

Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential.

Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, Merlin S, Talmon M, Novelli E, Diena M, Nicoletti C, Musarò A, Filigheddu N, Follenzi A, Prat M.

PLoS One. 2015 Sep 16;10(9):e0137999. doi: 10.1371/journal.pone.0137999. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0141632.

38.

Cell Penetrating Peptide Adsorption on Magnetite and Silica Surfaces: A Computational Investigation.

Grasso G, Deriu MA, Prat M, Rimondini L, Vernè E, Follenzi A, Danani A.

J Phys Chem B. 2015 Jul 2;119(26):8239-46. doi: 10.1021/jp512782e. Epub 2015 Jun 18.

PMID:
26042722
39.

Extrahepatic sources of factor VIII potentially contribute to the coagulation cascade correcting the bleeding phenotype of mice with hemophilia A.

Zanolini D, Merlin S, Feola M, Ranaldo G, Amoruso A, Gaidano G, Zaffaroni M, Ferrero A, Brunelleschi S, Valente G, Gupta S, Prat M, Follenzi A.

Haematologica. 2015 Jul;100(7):881-92. doi: 10.3324/haematol.2014.123117. Epub 2015 Apr 24.

40.

Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis.

Zavattari P, Perra A, Menegon S, Kowalik MA, Petrelli A, Angioni MM, Follenzi A, Quagliata L, Ledda-Columbano GM, Terracciano L, Giordano S, Columbano A.

Hepatology. 2015 Sep;62(3):851-62. doi: 10.1002/hep.27790. Epub 2015 Apr 22.

PMID:
25783764
41.

Mouse hepatocytes and LSEC proteome reveal novel mechanisms of ischemia/reperfusion damage and protection by A2aR stimulation.

Mandili G, Alchera E, Merlin S, Imarisio C, Chandrashekar BR, Riganti C, Bianchi A, Novelli F, Follenzi A, Carini R.

J Hepatol. 2015 Mar;62(3):573-80. doi: 10.1016/j.jhep.2014.10.007. Epub 2014 Oct 12.

42.

Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.

Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP.

Clin Exp Immunol. 2015 Mar;179(3):398-413. doi: 10.1111/cei.12465.

43.

Dissecting the transcriptional phenotype of ribosomal protein deficiency: implications for Diamond-Blackfan Anemia.

Aspesi A, Pavesi E, Robotti E, Crescitelli R, Boria I, Avondo F, Moniz H, Da Costa L, Mohandas N, Roncaglia P, Ramenghi U, Ronchi A, Gustincich S, Merlin S, Marengo E, Ellis SR, Follenzi A, Santoro C, Dianzani I.

Gene. 2014 Jul 25;545(2):282-9. doi: 10.1016/j.gene.2014.04.077. Epub 2014 May 15.

44.

Visualization of dynamics of single endogenous mRNA labeled in live mouse.

Park HY, Lim H, Yoon YJ, Follenzi A, Nwokafor C, Lopez-Jones M, Meng X, Singer RH.

Science. 2014 Jan 24;343(6169):422-4. doi: 10.1126/science.1239200.

45.

Monophasic and biphasic electrical stimulation induces a precardiac differentiation in progenitor cells isolated from human heart.

Pietronave S, Zamperone A, Oltolina F, Colangelo D, Follenzi A, Novelli E, Diena M, Pavesi A, Consolo F, Fiore GB, Soncini M, Prat M.

Stem Cells Dev. 2014 Apr 15;23(8):888-98. doi: 10.1089/scd.2013.0375. Epub 2014 Jan 24.

46.

Isolation and characterization of a spontaneously immortalized multipotent mesenchymal cell line derived from mouse subcutaneous adipose tissue.

Zamperone A, Pietronave S, Merlin S, Colangelo D, Ranaldo G, Medico E, Di Scipio F, Berta GN, Follenzi A, Prat M.

Stem Cells Dev. 2013 Nov 1;22(21):2873-84. doi: 10.1089/scd.2012.0718. Epub 2013 Aug 9.

47.

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

Scharf B, Clement CC, Wu XX, Morozova K, Zanolini D, Follenzi A, Larocca JN, Levon K, Sutterwala FS, Rand J, Cobelli N, Purdue E, Hajjar KA, Santambrogio L.

Nat Commun. 2012 Mar 27;3:755. doi: 10.1038/ncomms1754.

48.

Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.

Capozza F, Trimmer C, Castello-Cros R, Katiyar S, Whitaker-Menezes D, Follenzi A, Crosariol M, Llaverias G, Sotgia F, Pestell RG, Lisanti MP.

Cancer Res. 2012 May 1;72(9):2262-74. doi: 10.1158/0008-5472.CAN-11-2593. Epub 2012 Mar 6.

49.

N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.

Cotella D, Radicke S, Cipriani V, Cavaletto M, Merlin S, Follenzi A, Ravens U, Wettwer E, Santoro C, Sblattero D.

Int J Biochem Cell Biol. 2012 Jun;44(6):876-85. doi: 10.1016/j.biocel.2012.02.011. Epub 2012 Feb 22.

PMID:
22387313
50.

Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death.

Noh KM, Hwang JY, Follenzi A, Athanasiadou R, Miyawaki T, Greally JM, Bennett MV, Zukin RS.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E962-71. doi: 10.1073/pnas.1121568109. Epub 2012 Feb 27.

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