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Items: 16


Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double-Stranded DNA Donors.

Paix A, Rasoloson D, Folkmann A, Seydoux G.

Curr Protoc Mol Biol. 2019 Dec;129(1):e102. doi: 10.1002/cpmb.102.


P Granules Protect RNA Interference Genes from Silencing by piRNAs.

Ouyang JPT, Folkmann A, Bernard L, Lee CY, Seroussi U, Charlesworth AG, Claycomb JM, Seydoux G.

Dev Cell. 2019 Sep 23;50(6):716-728.e6. doi: 10.1016/j.devcel.2019.07.026. Epub 2019 Aug 8.


Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms.

Folkmann AW, Seydoux G.

Development. 2019 Mar 25;146(6). pii: dev171116. doi: 10.1242/dev.171116.


Single-molecule study reveals the frenetic lives of proteins in gradients.

Folkmann AW, Seydoux G.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9336-9338. doi: 10.1073/pnas.1812248115. Epub 2018 Sep 4. No abstract available.


Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks.

Paix A, Folkmann A, Goldman DH, Kulaga H, Grzelak MJ, Rasoloson D, Paidemarry S, Green R, Reed RR, Seydoux G.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10745-E10754. doi: 10.1073/pnas.1711979114. Epub 2017 Nov 28.


Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans.

Paix A, Folkmann A, Seydoux G.

Methods. 2017 May 15;121-122:86-93. doi: 10.1016/j.ymeth.2017.03.023. Epub 2017 Apr 7.


High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes.

Paix A, Folkmann A, Rasoloson D, Seydoux G.

Genetics. 2015 Sep;201(1):47-54. doi: 10.1534/genetics.115.179382. Epub 2015 Jul 17.


Cytoplasmic hGle1A regulates stress granules by modulation of translation.

Aditi, Folkmann AW, Wente SR.

Mol Biol Cell. 2015 Apr 15;26(8):1476-90. doi: 10.1091/mbc.E14-11-1523. Epub 2015 Feb 18.


Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis.

Kaneb HM, Folkmann AW, Belzil VV, Jao LE, Leblond CS, Girard SL, Daoud H, Noreau A, Rochefort D, Hince P, Szuto A, Levert A, Vidal S, André-Guimont C, Camu W, Bouchard JP, Dupré N, Rouleau GA, Wente SR, Dion PA.

Hum Mol Genet. 2015 Mar 1;24(5):1363-73. doi: 10.1093/hmg/ddu545. Epub 2014 Oct 24.


Insights into mRNA export-linked molecular mechanisms of human disease through a Gle1 structure-function analysis.

Folkmann AW, Dawson TR, Wente SR.

Adv Biol Regul. 2014 Jan;54:74-91. doi: 10.1016/j.jbior.2013.10.002. Epub 2013 Nov 13. Review.


Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease.

Folkmann AW, Collier SE, Zhan X, Aditi, Ohi MD, Wente SR.

Cell. 2013 Oct 24;155(3):582-93. doi: 10.1016/j.cell.2013.09.023. Epub 2013 Oct 24.


Dbp5, Gle1-IP6 and Nup159: a working model for mRNP export.

Folkmann AW, Noble KN, Cole CN, Wente SR.

Nucleus. 2011 Nov-Dec;2(6):540-8. doi: 10.4161/nucl.2.6.17881. Epub 2011 Nov 1. Review.


The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1.

Hodge CA, Tran EJ, Noble KN, Alcazar-Roman AR, Ben-Yishay R, Scarcelli JJ, Folkmann AW, Shav-Tal Y, Wente SR, Cole CN.

Genes Dev. 2011 May 15;25(10):1052-64. doi: 10.1101/gad.2041611.


Vinculin activators target integrins from within the cell to increase melanoma sensitivity to chemotherapy.

Nelson ES, Folkmann AW, Henry MD, DeMali KA.

Mol Cancer Res. 2011 Jun;9(6):712-23. doi: 10.1158/1541-7786.MCR-10-0599. Epub 2011 Apr 1.


Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells.

Miller PM, Folkmann AW, Maia AR, Efimova N, Efimov A, Kaverina I.

Nat Cell Biol. 2009 Sep;11(9):1069-80. doi: 10.1038/ncb1920. Epub 2009 Aug 23.


The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation.

Bolger TA, Folkmann AW, Tran EJ, Wente SR.

Cell. 2008 Aug 22;134(4):624-33. doi: 10.1016/j.cell.2008.06.027.

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