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Isolation of sutherlandins A, B, C and D from Sutherlandia frutescens (L.) R. Br. by counter-current chromatography using spiral tubing support rotors.

Chen C, Folk WR, Lazo-Portugal R, Finn TM, Knight M.

J Chromatogr A. 2017 Jul 28;1508:7-15. doi: 10.1016/j.chroma.2017.05.027. Epub 2017 May 22.


Chilling susceptibility in mungbean varieties is associated with their differentially expressed genes.

Chen LR, Ko CY, Folk WR, Lin TY.

Bot Stud. 2017 Dec;58(1):7. doi: 10.1186/s40529-017-0161-2. Epub 2017 Jan 9.


An Investigation into the Immunomodulatory Activities of Sutherlandia frutescens in Healthy Mice.

Lei W, Browning JD Jr, Eichen PA, Folk WR, Sun GY, Lubahn DB, Fritsche KL.

PLoS One. 2016 Aug 30;11(8):e0160994. doi: 10.1371/journal.pone.0160994. eCollection 2016.


Rapid and efficient Agrobacterium-mediated transformation of sorghum (Sorghum bicolor) employing standard binary vectors and bar gene as a selectable marker.

Do PT, Lee H, Mookkan M, Folk WR, Zhang ZJ.

Plant Cell Rep. 2016 Oct;35(10):2065-76. doi: 10.1007/s00299-016-2019-6. Epub 2016 Jun 27.


Multilevel Assessment of Middle School Students' Interest in the Health Sciences: Development and Validation of a New Measurement Tool.

Romine WL, Miller ME, Knese SA, Folk WR.

CBE Life Sci Educ. 2016 Summer;15(2). pii: ar21. doi: 10.1187/cbe.15-02-0034.


Phytochemicals and botanical extracts regulate NF-κB and Nrf2/ARE reporter activities in DI TNC1 astrocytes.

Ajit D, Simonyi A, Li R, Chen Z, Hannink M, Fritsche KL, Mossine VV, Smith RE, Dobbs TK, Luo R, Folk WR, Gu Z, Lubahn DB, Weisman GA, Sun GY.

Neurochem Int. 2016 Jul;97:49-56. doi: 10.1016/j.neuint.2016.05.004. Epub 2016 May 7.


Does Concurrent Use of Some Botanicals Interfere with Treatment of Tuberculosis?

Folk WR, Smith A, Song H, Chuang D, Cheng J, Gu Z, Sun G.

Neuromolecular Med. 2016 Sep;18(3):483-6. doi: 10.1007/s12017-016-8402-1. Epub 2016 May 7. Review.


Inhibition of Hedgehog-Signaling Driven Genes in Prostate Cancer Cells by Sutherlandia frutescens Extract.

Lu Y, Starkey N, Lei W, Li J, Cheng J, Folk WR, Lubahn DB.

PLoS One. 2015 Dec 28;10(12):e0145507. doi: 10.1371/journal.pone.0145507. eCollection 2015.


Unveiling the anti-inflammatory activity of Sutherlandia frutescens using murine macrophages.

Lei W, Browning JD Jr, Eichen PA, Brownstein KJ, Folk WR, Sun GY, Lubahn DB, Rottinghaus GE, Fritsche KL.

Int Immunopharmacol. 2015 Dec;29(2):254-262. doi: 10.1016/j.intimp.2015.11.012. Epub 2015 Nov 12.


Inhibition of Gli/hedgehog signaling in prostate cancer cells by "cancer bush" Sutherlandia frutescens extract.

Lin H, Jackson GA, Lu Y, Drenkhahn SK, Brownstein KJ, Starkey NJ, Lamberson WR, Fritsche KL, Mossine VV, Besch-Williford CL, Folk WR, Zhang Y, Lubahn DB.

Cell Biol Int. 2016 Feb;40(2):131-42. doi: 10.1002/cbin.10544. Epub 2015 Oct 6.


Consumption of Sutherlandia frutescens by HIV-Seropositive South African Adults: An Adaptive Double-Blind Randomized Placebo Controlled Trial.

Wilson D, Goggin K, Williams K, Gerkovich MM, Gqaleni N, Syce J, Bartman P, Johnson Q, Folk WR.

PLoS One. 2015 Jul 17;10(7):e0128522. doi: 10.1371/journal.pone.0128522. eCollection 2015.


Immuno-stimulatory activity of a polysaccharide-enriched fraction of Sutherlandia frutescens occurs by the toll-like receptor-4 signaling pathway.

Lei W, Browning JD Jr, Eichen PA, Lu CH, Mossine VV, Rottinghaus GE, Folk WR, Sun GY, Lubahn DB, Fritsche KL.

J Ethnopharmacol. 2015 Aug 22;172:247-53. doi: 10.1016/j.jep.2015.06.013. Epub 2015 Jun 18.


From Gigabyte to Kilobyte: A Bioinformatics Protocol for Mining Large RNA-Seq Transcriptomics Data.

Li J, Hou J, Sun L, Wilkins JM, Lu Y, Niederhuth CE, Merideth BR, Mawhinney TP, Mossine VV, Greenlief CM, Walker JC, Folk WR, Hannink M, Lubahn DB, Birchler JA, Cheng J.

PLoS One. 2015 Apr 22;10(4):e0125000. doi: 10.1371/journal.pone.0125000. eCollection 2015.


Arabidopsis thaliana MSI4/FVE associates with members of a novel family of plant specific PWWP/RRM domain proteins.

Kenzior A, Folk WR.

Plant Mol Biol. 2015 Mar;87(4-5):329-39. doi: 10.1007/s11103-014-0280-z. Epub 2015 Jan 20.


Dietary Sutherlandia and elderberry mitigate cerebral ischemia-induced neuronal damage and attenuate p47phox and phospho-ERK1/2 expression in microglial cells.

Chuang DY, Cui J, Simonyi A, Engel VA, Chen S, Fritsche KL, Thomas AL, Applequist WL, Folk WR, Lubahn DB, Sun AY, Sun GY, Gu Z.

ASN Neuro. 2014 Oct 16;6(6). pii: 1759091414554946. doi: 10.1177/1759091414554946. Print 2014.


Antioxidant potential of Sutherlandia frutescens and its protective effects against oxidative stress in various cell cultures.

Tobwala S, Fan W, Hines CJ, Folk WR, Ercal N.

BMC Complement Altern Med. 2014 Jul 29;14:271. doi: 10.1186/1472-6882-14-271.


Sutherlandia frutescens ethanol extracts inhibit oxidative stress and inflammatory responses in neurons and microglial cells.

Jiang J, Chuang DY, Zong Y, Patel J, Brownstein K, Lei W, Lu CH, Simonyi A, Gu Z, Cui J, Rottinghaus GE, Fritsche KL, Lubahn DB, Folk WR, Sun GY.

PLoS One. 2014 Feb 25;9(2):e89748. doi: 10.1371/journal.pone.0089748. eCollection 2014.


Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients.

Lee JH, Hachiya A, Shin SK, Lee J, Gatanaga H, Oka S, Kirby KA, Ong YT, Sarafianos SG, Folk WR, Yoo W, Hong SP, Kim SO.

Clin Microbiol Infect. 2013 Jun;19(6):E263-70. doi: 10.1111/1469-0691.12167. Epub 2013 Mar 11.


21st century natural product research and drug development and traditional medicines.

Ngo LT, Okogun JI, Folk WR.

Nat Prod Rep. 2013 Apr;30(4):584-92. doi: 10.1039/c3np20120a. Review.


Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells.

Chuang DY, Chan MH, Zong Y, Sheng W, He Y, Jiang JH, Simonyi A, Gu Z, Fritsche KL, Cui J, Lee JC, Folk WR, Lubahn DB, Sun AY, Sun GY.

J Neuroinflammation. 2013 Jan 29;10:15. doi: 10.1186/1742-2094-10-15.


Femtogram-level detection of Clostridium botulinum neurotoxin type A by sandwich immunoassay using nanoporous substrate and ultra-bright fluorescent suprananoparticles.

Bok S, Korampally V, Darr CM, Folk WR, Polo-Parada L, Gangopadhyay K, Gangopadhyay S.

Biosens Bioelectron. 2013 Mar 15;41:409-16. doi: 10.1016/j.bios.2012.08.063. Epub 2012 Sep 19.


Antiviral therapies: focus on hepatitis B reverse transcriptase.

Michailidis E, Kirby KA, Hachiya A, Yoo W, Hong SP, Kim SO, Folk WR, Sarafianos SG.

Int J Biochem Cell Biol. 2012 Jul;44(7):1060-71. doi: 10.1016/j.biocel.2012.04.006. Epub 2012 Apr 16. Review.


Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots.

Michailidis E, Singh K, Kirby KA, Hachiya A, Yoo W, Hong SP, Kim SO, Folk WR, Sarafianos SG.

Int J Curr Chem. 2011 Oct;2(4):253-260.


Confeito-like assembly of organosilicate-caged fluorophores: ultrabright suprananoparticles for fluorescence imaging.

Bok S, Korampally V, Polo-Parada L, Mamidi V, Baker GA, Gangopadhyay K, Folk WR, Dasgupta PK, Gangopadhyay S.

Nanotechnology. 2012 May 4;23(17):175601. doi: 10.1088/0957-4484/23/17/175601. Epub 2012 Apr 5.


Stimulation of BK virus DNA replication by NFI family transcription factors.

Liang B, Tikhanovich I, Nasheuer HP, Folk WR.

J Virol. 2012 Mar;86(6):3264-75. doi: 10.1128/JVI.06369-11. Epub 2011 Dec 28.


Effect of short term and chronic administration of Sutherlandia frutescens on pharmacokinetics of nevirapine in rats.

Minocha M, Mandava NK, Kwatra D, Pal D, Folk WR, Earla R, Mitra AK.

Int J Pharm. 2011 Jul 15;413(1-2):44-50. doi: 10.1016/j.ijpharm.2011.04.051. Epub 2011 Apr 23.


Inhibition of human BK polyomavirus replication by small noncoding RNAs.

Tikhanovich I, Liang B, Seoighe C, Folk WR, Nasheuer HP.

J Virol. 2011 Jul;85(14):6930-40. doi: 10.1128/JVI.00547-11. Epub 2011 May 4.


Identification of a beta-casein-like peptide in breast nipple aspirate fluid that is associated with breast cancer.

Sauter ER, Davis W, Qin W, Scanlon S, Mooney B, Bromert K, Folk WR.

Biomark Med. 2009 Oct;3(5):577-88. doi: 10.2217/bmm.09.46.


Efficacy of Artemisia afra phytotherapy in experimental tuberculosis.

Ntutela S, Smith P, Matika L, Mukinda J, Arendse H, Allie N, Estes DM, Mabusela W, Folb P, Steyn L, Johnson Q, Folk WR, Syce J, Jacobs M.

Tuberculosis (Edinb). 2009 Dec;89 Suppl 1:S33-40. doi: 10.1016/S1472-9792(09)70009-5.


Restriction of human polyomavirus BK virus DNA replication in murine cells and extracts.

Mahon C, Liang B, Tikhanovich I, Abend JR, Imperiale MJ, Nasheuer HP, Folk WR.

J Virol. 2009 Jun;83(11):5708-17. doi: 10.1128/JVI.00300-09. Epub 2009 Mar 18.


High-resolution human papillomavirus genotyping by MALDI-TOF mass spectrometry.

Hong SP, Shin SK, Lee EH, Kim EO, Ji SI, Chung HJ, Park SN, Yoo W, Folk WR, Kim SO.

Nat Protoc. 2008;3(9):1476-84. doi: 10.1038/nprot.2008.136.


Abandonment of antiretroviral therapy: a potential barrier to scale-up in sub-Saharan Africa.

Reid SE, Mulenga LB, Folk WR, Tambatamba BC, Chi BH.

S Afr Med J. 2008 Jun;98(6):448, 450. No abstract available.


A randomized, double-blind, placebo-controlled trial of Lessertia frutescens in healthy adults.

Johnson Q, Syce J, Nell H, Rudeen K, Folk WR.

PLoS Clin Trials. 2007 Apr 27;2(4):e16.


Altered expression of plant lysyl tRNA synthetase promotes tRNA misacylation and translational recoding of lysine.

Wu XR, Kenzior A, Willmot D, Scanlon S, Chen Z, Topin A, He SH, Acevedo A, Folk WR.

Plant J. 2007 May;50(4):627-36. Epub 2007 Apr 8.


Visualizing bz1 missense suppression in Zea mays: an assay for monocot tRNA expression and utilization.

Wu XR, Chen Z, Shende A, Dooner HK, Folk WR.

Plant Mol Biol. 2006 Jul;61(4-5):795-8.


Inhibition of polyomavirus ori-dependent DNA replication by mSin3B.

Xie AY, Folk WR.

J Virol. 2002 Dec;76(23):11809-18.


NMR structure of the N-terminal J domain of murine polyomavirus T antigens. Implications for DnaJ-like domains and for mutations of T antigens.

Berjanskii MV, Riley MI, Xie A, Semenchenko V, Folk WR, Van Doren SR.

J Biol Chem. 2000 Nov 17;275(46):36094-103.


AtMSI4 and RbAp48 WD-40 repeat proteins bind metal ions.

Kenzior AL, Folk WR.

FEBS Lett. 1998 Dec 4;440(3):425-9.


Identity elements and aminoacylation of plant tRNATrp.

Ulmasov B, Topin A, Chen Z, He SH, Folk WR.

Nucleic Acids Res. 1998 Nov 15;26(22):5139-41.


Nonsense and missense translational suppression in plant cells mediated by tRNA(Lys).

Chen Z, Ulmasov B, Folk WR.

Plant Mol Biol. 1998 Jan;36(1):163-70.


Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain.

Riley MI, Yoo W, Mda NY, Folk WR.

J Virol. 1997 Aug;71(8):6068-74.


AP1 enhances polyomavirus DNA replication by promoting T-antigen-mediated unwinding of DNA.

Guo W, Tang WJ, Bu X, Bermudez V, Martin M, Folk WR.

J Virol. 1996 Aug;70(8):4914-8.


Hsp70 heat shock protein cognate is expressed and stored in developing tomato pollen.

Duck NB, Folk WR.

Plant Mol Biol. 1994 Nov;26(4):1031-9.


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