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Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice.

Oakley RH, Cruz-Topete D, He B, Foley JF, Myers PH, Xu X, Gomez-Sanchez CE, Chambon P, Willis MS, Cidlowski JA.

Sci Signal. 2019 Apr 16;12(577). pii: eaau9685. doi: 10.1126/scisignal.aau9685.


Evaluation of natalizumab pharmacokinetics and pharmacodynamics with standard and extended interval dosing.

Foley JF, Goelz S, Hoyt T, Christensen A, Metzger RR.

Mult Scler Relat Disord. 2019 Jun;31:65-71. doi: 10.1016/j.msard.2019.03.017. Epub 2019 Mar 26.


DNA methylation in mice is influenced by genetics as well as sex and life experience.

Grimm SA, Shimbo T, Takaku M, Thomas JW, Auerbach S, Bennett BD, Bucher JR, Burkholder AB, Day F, Du Y, Duncan CG, French JE, Foley JF, Li J, Merrick BA, Tice RR, Wang T, Xu X; NISC Comparative Sequencing Program, Bushel PR, Fargo DC, Mullikin JC, Wade PA.

Nat Commun. 2019 Jan 18;10(1):305. doi: 10.1038/s41467-018-08067-z.


NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system.

French CD, Willoughby RE, Pan A, Wong SJ, Foley JF, Wheat LJ, Fernandez J, Encarnacion R, Ondrush JM, Fatteh N, Paez A, David D, Javaid W, Amzuta IG, Neilan AM, Robbins GK, Brunner AM, Hu WT, Mishchuk DO, Slupsky CM.

PLoS Negl Trop Dis. 2018 Dec 17;12(12):e0007045. doi: 10.1371/journal.pntd.0007045. eCollection 2018 Dec.


Whole exome sequencing in the rat.

Foley JF, Phadke DP, Hardy O, Hardy S, Miller V, Madan A, Howard K, Kruse K, Lord C, Ramaiahgari S, Solomon GG, Shah RR, Pandiri AR, Herbert RA, Sills RC, Merrick BA.

BMC Genomics. 2018 Jun 20;19(1):487. doi: 10.1186/s12864-018-4858-8.


Glucocorticoid receptor isoform-specific regulation of development, circadian rhythm, and inflammation in mice.

Oakley RH, Ramamoorthy S, Foley JF, Busada JT, Lu NZ, Cidlowski JA.

FASEB J. 2018 Oct;32(10):5258-5271. doi: 10.1096/fj.201701153R. Epub 2018 Apr 19.


Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype.

Xu P, Morrison JP, Foley JF, Stumpo DJ, Ward T, Zeldin DC, Blackshear PJ.

PLoS One. 2018 Jan 3;13(1):e0190561. doi: 10.1371/journal.pone.0190561. eCollection 2018.


Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.

Tang S, Fang Y, Huang G, Xu X, Padilla-Banks E, Fan W, Xu Q, Sanderson SM, Foley JF, Dowdy S, McBurney MW, Fargo DC, Williams CJ, Locasale JW, Guan Z, Li X.

EMBO J. 2017 Nov 2;36(21):3175-3193. doi: 10.15252/embj.201796708. Epub 2017 Oct 11.


Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5.

Chen VS, Morrison JP, Southwell MF, Foley JF, Bolon B, Elmore SA.

Toxicol Pathol. 2017 Aug;45(6):705-744. doi: 10.1177/0192623317728134. Epub 2017 Sep 11.


Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biological sero-converters.

Schwab N, Schneider-Hohendorf T, Hoyt T, Gross CC, Meuth SG, Klotz L, Foley JF, Wiendl H.

Mult Scler. 2018 Apr;24(5):563-573. doi: 10.1177/1352458517728814. Epub 2017 Aug 29. Review.


Sectioning Mammary Gland Whole Mounts for Lesion Identification.

Tucker DK, Foley JF, Bouknight SA, Fenton SE.

J Vis Exp. 2017 Jul 24;(125). doi: 10.3791/55796.


Baseline EEG abnormalities in mild traumatic brain injury from the BIMA study.

Williams CS, Spitz MC, Foley JF, Weaver LK, Lindblad AS, Wierzbicki MR.

Undersea Hyperb Med. 2016 Aug-Sept;43(5):521-530.


Heart failure inhibitor.

Foley JF.

Sci Signal. 2017 Jul 11;10(487). pii: eaao3132. doi: 10.1126/scisignal.aao3132.


Long-term natalizumab treatment is associated with sustained improvements in quality of life in patients with multiple sclerosis.

Foley JF, Nair KV, Vollmer T, Stephenson JJ, Niecko T, Agarwal SS, Watson C.

Patient Prefer Adherence. 2017 Jun 16;11:1035-1048. doi: 10.2147/PPA.S134865. eCollection 2017.


New connections: Manipulating NK cell responses.

Foley JF.

Sci Signal. 2017 May 30;10(481). pii: eaan8369. doi: 10.1126/scisignal.aan8369.


Receptor cooperation in B cells.

Foley JF.

Sci Signal. 2017 May 23;10(480). pii: eaan7951. doi: 10.1126/scisignal.aan7951.


Shutting down innate immune responses during fertilization.

Foley JF.

Sci Signal. 2017 May 2;10(477). pii: eaan5400. doi: 10.1126/scisignal.aan5400.


Interferon-independent antiviral defense.

Foley JF.

Science. 2017 Apr 28;356(6336):392-394. doi: 10.1126/science.356.6336.392-q. No abstract available.


sTREM2 and neuroinflammation.

Foley JF.

Sci Signal. 2017 Mar 14;10(470). pii: eaan1468. doi: 10.1126/scisignal.aan1468.


Flexible control of T cell activation.

Foley JF.

Science. 2017 Mar 10;355(6329):1035-1036. doi: 10.1126/science.355.6329.1035-g. No abstract available.


How red berries reduce inflammation.

Foley JF.

Science. 2017 Feb 24;355(6327):808-809. doi: 10.1126/science.355.6327.808-h. Epub 2017 Feb 23. No abstract available.


An encephalitis-boosting microRNA.

Foley JF.

Science. 2017 Feb 17;355(6326):706-708. doi: 10.1126/science.355.6326.706-p. No abstract available.


TAK1 regulates resident macrophages by protecting lysosomal integrity.

Sakamachi Y, Morioka S, Mihaly SR, Takaesu G, Foley JF, Fessler MB, Ninomiya-Tsuji J.

Cell Death Dis. 2017 Feb 9;8(2):e2598. doi: 10.1038/cddis.2017.23.


Calcineurin for T cell adhesion.

Foley JF.

Sci Signal. 2017 Feb 7;10(465). pii: eaam9146. doi: 10.1126/scisignal.aam9146.


Overactive antiviral responses in lupus.

Foley JF.

Science. 2016 Dec 2;354(6316):1114-1115. No abstract available.


CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State.

Zheng X, Yang P, Lackford B, Bennett BD, Wang L, Li H, Wang Y, Miao Y, Foley JF, Fargo DC, Jin Y, Williams CJ, Jothi R, Hu G.

Stem Cell Reports. 2016 Nov 8;7(5):897-910. doi: 10.1016/j.stemcr.2016.09.007. Epub 2016 Oct 13.


Mammary Gland Evaluation in Juvenile Toxicity Studies: Temporal Developmental Patterns in the Male and Female Harlan Sprague-Dawley Rat.

Filgo AJ, Foley JF, Puvanesarajah S, Borde AR, Midkiff BR, Reed CE, Chappell VA, Alexander LB, Borde PR, Troester MA, Bouknight SA, Fenton SE.

Toxicol Pathol. 2016 Oct;44(7):1034-58. doi: 10.1177/0192623316663864. Epub 2016 Sep 9.


Preparation of High-quality Hematoxylin and Eosin-stained Sections from Rodent Mammary Gland Whole Mounts for Histopathologic Review.

Tucker DK, Foley JF, Hayes-Bouknight SA, Fenton SE.

Toxicol Pathol. 2016 Oct;44(7):1059-64. doi: 10.1177/0192623316660769. Epub 2016 Jul 29.


Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice.

Cruz-Topete D, Myers PH, Foley JF, Willis MS, Cidlowski JA.

Endocrinology. 2016 Jul;157(7):2759-71. doi: 10.1210/en.2015-1604. Epub 2016 May 24.


Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest.

Singh AP, Foley JF, Rubino M, Boyle MC, Tandon A, Shah R, Archer TK.

Mol Cell Biol. 2016 Jul 14;36(15):1990-2010. doi: 10.1128/MCB.01101-15. Print 2016 Aug 1.


Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development.

Swartley OM, Foley JF, Livingston DP 3rd, Cullen JM, Elmore SA.

Toxicol Pathol. 2016 Jul;44(5):705-25. doi: 10.1177/0192623316630836. Epub 2016 Mar 8.


Selectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific.

Singh SP, Foley JF, Zhang HH, Hurt DE, Richards JL, Smith CS, Liao F, Farber JM.

Mol Pharmacol. 2015 Nov;88(5):894-910. doi: 10.1124/mol.115.099960. Epub 2015 Aug 27.


Focus issue: Inflammatory mechanisms.

Foley JF.

Sci Signal. 2015 Mar 3;8(366):eg2. doi: 10.1126/scisignal.aaa9599.


F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation.

Harvey JB, Hong HH, Bhusari S, Ton TV, Wang Y, Foley JF, Peddada SD, Hooth M, DeVito M, Nyska A, Pandiri AR, Hoenerhoff MJ.

Vet Pathol. 2016 Jan;53(1):170-81. doi: 10.1177/0300985815571680. Epub 2015 Mar 2.


Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats.

Morgan DL, Merrick BA, Gerrish KE, Stockton PS, Wang Y, Foley JF, Gwinn WM, Kelly FL, Palmer SM, Ton TV, Flake GP.

PLoS One. 2015 Feb 24;10(2):e0118459. doi: 10.1371/journal.pone.0118459. eCollection 2015.


Body weight-based natalizumab treatment in adult patients with multiple sclerosis.

Tanaka M, Kinoshita M, Foley JF, Tanaka K, Kira J, Carroll WM.

J Neurol. 2015 Mar;262(3):781-2. doi: 10.1007/s00415-015-7655-1. Epub 2015 Feb 7. No abstract available.


Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice.

Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Foley JF, Flagler N, Ney E, Suksamrarn A, Piyachaturawat P, Bushel PR, Korach KS.

Environ Health Perspect. 2015 Apr;123(4):344-52. doi: 10.1289/ehp.1307935. Epub 2015 Jan 9.


The TRUST (EvaluaTion of Bladder Function in Relapsing-Remitting MUltiple Sclerosis Patients Treated with Natalizumab) Observational Study.

Khatri BO, Foley JF, Fink J, Kramer JF, Cha C, You X, Warth JD, Foulds P.

Int J MS Care. 2014 Spring;16(1):40-7. doi: 10.7224/1537-2073.2013-003.


NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.

Chrysovergis K, Wang X, Kosak J, Lee SH, Kim JS, Foley JF, Travlos G, Singh S, Baek SJ, Eling TE.

Int J Obes (Lond). 2014 Dec;38(12):1555-64. doi: 10.1038/ijo.2014.27. Epub 2014 Feb 17.


Optimizing therapeutics in the management of patients with multiple sclerosis: a review of drug efficacy, dosing, and mechanisms of action.

Damal K, Stoker E, Foley JF.

Biologics. 2013;7:247-58. doi: 10.2147/BTT.S53007. Epub 2013 Nov 27. Review.


A prospective trial of hyperbaric oxygen for chronic sequelae after brain injury (HYBOBI).

Churchill S, Weaver LK, Deru K, Russo AA, Handrahan D, Orrison WW Jr, Foley JF, Elwell HA.

Undersea Hyperb Med. 2013 Mar-Apr;40(2):165-93.


In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor.

Podolin PL, Bolognese BJ, Foley JF, Long E 3rd, Peck B, Umbrecht S, Zhang X, Zhu P, Schwartz B, Xie W, Quinn C, Qi H, Sweitzer S, Chen S, Galop M, Ding Y, Belyanskaya SL, Israel DI, Morgan BA, Behm DJ, Marino JP Jr, Kurali E, Barnette MS, Mayer RJ, Booth-Genthe CL, Callahan JF.

Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:25-31. doi: 10.1016/j.prostaglandins.2013.02.001. Epub 2013 Feb 19.


Intramuscular interferon beta-1a and evolving treatment options and outcomes measurement for MS: considerations for managed care.

Barnes CJ, Caon C, Foley JF, Friedman M, Menzin J, Nair KV, Nichols C, Olvey EL, Owens GM, Pill MW, Skrepnek GH, White LA, Zerkowski K.

J Manag Care Pharm. 2013 Jan-Feb;19(1 Suppl A):S1-53. No abstract available.


Emerging methods for evaluating the effectiveness of intramuscular interferon beta-1a for relapsing-remitting multiple sclerosis.

Foley JF, Barnes CJ, Nair KV.

J Manag Care Pharm. 2013 Jan-Feb;19(1 Suppl A):S16-23. Review.


Focus issue: understanding mechanisms of inflammation.

Foley JF.

Sci Signal. 2013 Jan 15;6(258):eg2. doi: 10.1126/scisignal.2003938.


Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance.

Humble MM, Young MJ, Foley JF, Pandiri AR, Travlos GS, Copeland WC.

Hum Mol Genet. 2013 Mar 1;22(5):1017-25. doi: 10.1093/hmg/dds506. Epub 2012 Nov 29.


The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens.

Wilson RH, Maruoka S, Whitehead GS, Foley JF, Flake GP, Sever ML, Zeldin DC, Kraft M, Garantziotis S, Nakano H, Cook DN.

Nat Med. 2012 Nov;18(11):1705-10. doi: 10.1038/nm.2920. Epub 2012 Oct 14.


Focus issue: regulation of lymphocyte function.

Andrianantoandro E, Foley JF.

Sci Signal. 2012 Jul 31;5(235):eg8. doi: 10.1126/scisignal.2003412.


Testing an aflatoxin B1 gene signature in rat archival tissues.

Merrick BA, Auerbach SS, Stockton PS, Foley JF, Malarkey DE, Sills RC, Irwin RD, Tice RR.

Chem Res Toxicol. 2012 May 21;25(5):1132-44. doi: 10.1021/tx3000945. Epub 2012 May 4.

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