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Items: 40

1.

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids.

Bolhaqueiro ACF, Ponsioen B, Bakker B, Klaasen SJ, Kucukkose E, van Jaarsveld RH, Vivié J, Verlaan-Klink I, Hami N, Spierings DCJ, Sasaki N, Dutta D, Boj SF, Vries RGJ, Lansdorp PM, van de Wetering M, van Oudenaarden A, Clevers H, Kranenburg O, Foijer F, Snippert HJG, Kops GJPL.

Nat Genet. 2019 May;51(5):824-834. doi: 10.1038/s41588-019-0399-6. Epub 2019 Apr 29.

PMID:
31036964
2.

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors.

Pillay N, Tighe A, Nelson L, Littler S, Coulson-Gilmer C, Bah N, Golder A, Bakker B, Spierings DCJ, James DI, Smith KM, Jordan AM, Morgan RD, Ogilvie DJ, Foijer F, Jackson DA, Taylor SS.

Cancer Cell. 2019 Mar 18;35(3):519-533.e8. doi: 10.1016/j.ccell.2019.02.004.

3.

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.

Aziz K, Limzerwala JF, Sturmlechner I, Hurley E, Zhang C, Jeganathan KB, Nelson G, Bronk S, Fierro Velasco RO, van Deursen EJ, O'Brien DR, Kocher JA, Youssef SA, van Ree JH, de Bruin A, van den Bos H, Spierings DCJ, Foijer F, van de Sluis B, Roberts LR, Gores GJ, Li H, van Deursen JM.

Gastroenterology. 2019 Jul;157(1):210-226.e12. doi: 10.1053/j.gastro.2019.03.016. Epub 2019 Mar 13.

PMID:
30878468
4.

Quantification of Aneuploidy in Mammalian Systems.

van den Bos H, Bakker B, Taudt A, Guryev V, Colomé-Tatché M, Lansdorp PM, Foijer F, Spierings DCJ.

Methods Mol Biol. 2019;1896:159-190. doi: 10.1007/978-1-4939-8931-7_15.

PMID:
30474848
5.

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α.

Simões-Sousa S, Littler S, Thompson SL, Minshall P, Whalley H, Bakker B, Belkot K, Moralli D, Bronder D, Tighe A, Spierings DCJ, Bah N, Graham J, Nelson L, Green CM, Foijer F, Townsend PA, Taylor SS.

Cell Rep. 2018 Oct 16;25(3):749-760.e6. doi: 10.1016/j.celrep.2018.09.060.

6.

Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells.

Benedict B, van Harn T, Dekker M, Hermsen S, Kucukosmanoglu A, Pieters W, Delzenne-Goette E, Dorsman JC, Petermann E, Foijer F, Te Riele H.

Elife. 2018 Oct 16;7. pii: e37868. doi: 10.7554/eLife.37868.

7.

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.

van Gijn SE, Wierenga E, van den Tempel N, Kok YP, Heijink AM, Spierings DCJ, Foijer F, van Vugt MATM, Fehrmann RSN.

Oncogene. 2019 Feb;38(6):852-867. doi: 10.1038/s41388-018-0470-2. Epub 2018 Sep 3.

8.

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.

Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E.

Nat Commun. 2018 Jul 19;9(1):2834. doi: 10.1038/s41467-018-05258-6.

9.

Non-random Mis-segregation of Human Chromosomes.

Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E, Foijer F, McClelland SE.

Cell Rep. 2018 Jun 12;23(11):3366-3380. doi: 10.1016/j.celrep.2018.05.047.

10.

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

Wielders CLC, van Nierop P, Vormer TL, Foijer F, Verheij J, Lodder JC, Andersen JB, Mansvelder HD, Te Riele H.

PLoS One. 2018 May 22;13(5):e0196979. doi: 10.1371/journal.pone.0196979. eCollection 2018.

11.

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM.

Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089.

12.

CIN and Aneuploidy: Different Concepts, Different Consequences.

Schukken KM, Foijer F.

Bioessays. 2018 Jan;40(1). doi: 10.1002/bies.201700147. Epub 2017 Nov 21. Review.

PMID:
29160563
13.

Single-cell sequencing to quantify genomic integrity in cancer.

van den Bos H, Bakker B, Spierings DCJ, Lansdorp PM, Foijer F.

Int J Biochem Cell Biol. 2018 Jan;94:146-150. doi: 10.1016/j.biocel.2017.09.016. Epub 2017 Sep 23. Review.

PMID:
28951245
14.

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

Schoonen PM, Talens F, Stok C, Gogola E, Heijink AM, Bouwman P, Foijer F, Tarsounas M, Blatter S, Jonkers J, Rottenberg S, van Vugt MATM.

Nat Commun. 2017 Jul 17;8:15981. doi: 10.1038/ncomms15981.

15.

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies.

Soto M, Raaijmakers JA, Bakker B, Spierings DCJ, Lansdorp PM, Foijer F, Medema RH.

Cell Rep. 2017 Jun 20;19(12):2423-2431. doi: 10.1016/j.celrep.2017.05.055.

16.

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

Bockaj I, Bruggeman SWM, Foijer F.

Bioessays. 2017 Jul;39(7). doi: 10.1002/bies.201700084. Epub 2017 Jun 14. No abstract available.

PMID:
28612937
17.

Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small-cell lung cancer patient.

Ferronika P, van den Bos H, Taudt A, Spierings DCJ, Saber A, Hiltermann TJN, Kok K, Porubsky D, van der Wekken AJ, Timens W, Foijer F, Colomé-Tatché M, Groen HJM, Lansdorp PM, van den Berg A.

Ann Oncol. 2017 Jul 1;28(7):1668-1670. doi: 10.1093/annonc/mdx182. No abstract available.

PMID:
28419234
18.

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.

Foijer F, Albacker LA, Bakker B, Spierings DC, Yue Y, Xie SZ, Davis S, Lutum-Jehle A, Takemoto D, Hare B, Furey B, Bronson RT, Lansdorp PM, Bradley A, Sorger PK.

Elife. 2017 Mar 20;6. pii: e20873. doi: 10.7554/eLife.20873.

19.

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals.

Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ.

Dev Cell. 2017 Feb 6;40(3):313-322.e5. doi: 10.1016/j.devcel.2016.12.022. Epub 2017 Jan 26.

20.

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

van den Bos H, Spierings DC, Taudt A, Bakker B, Porubský D, Falconer E, Novoa C, Halsema N, Kazemier HG, Hoekstra-Wakker K, Guryev V, den Dunnen WF, Foijer F, Colomé-Tatché M, Boddeke HW, Landsdorp PM.

Genome Biol. 2016 Jun 30;17(1):143. No abstract available.

21.

Aneuploidy in stem cells.

Garcia-Martinez J, Bakker B, Schukken KM, Simon JE, Foijer F.

World J Stem Cells. 2016 Jun 26;8(6):216-22. doi: 10.4252/wjsc.v8.i6.216. Review.

22.

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

van den Bos H, Spierings DC, Taudt AS, Bakker B, Porubský D, Falconer E, Novoa C, Halsema N, Kazemier HG, Hoekstra-Wakker K, Guryev V, den Dunnen WF, Foijer F, Tatché MC, Boddeke HW, Lansdorp PM.

Genome Biol. 2016 May 31;17(1):116. doi: 10.1186/s13059-016-0976-2. Erratum in: Genome Biol. 2016 Jun 30;17(1):143.

23.

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies.

Bakker B, Taudt A, Belderbos ME, Porubsky D, Spierings DC, de Jong TV, Halsema N, Kazemier HG, Hoekstra-Wakker K, Bradley A, de Bont ES, van den Berg A, Guryev V, Lansdorp PM, Colomé-Tatché M, Foijer F.

Genome Biol. 2016 May 31;17(1):115. doi: 10.1186/s13059-016-0971-7.

24.

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

Heijink AM, Blomen VA, Bisteau X, Degener F, Matsushita FY, Kaldis P, Foijer F, van Vugt MA.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15160-5. doi: 10.1073/pnas.1505283112. Epub 2015 Nov 23.

25.

CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?

Simon JE, Bakker B, Foijer F.

Recent Results Cancer Res. 2015;200:39-60. doi: 10.1007/978-3-319-20291-4_2. Review.

PMID:
26376871
26.

How to count chromosomes in a cell: An overview of current and novel technologies.

Bakker B, van den Bos H, Lansdorp PM, Foijer F.

Bioessays. 2015 May;37(5):570-7. doi: 10.1002/bies.201400218. Epub 2015 Mar 4. Review.

PMID:
25739518
27.

Better check late than never: The chromosome segregation checkpoint (comment on DOI 10.1002/bies.201400140).

Oliveira VL, Foijer F.

Bioessays. 2015 Mar;37(3):235-6. doi: 10.1002/bies.201400212. Epub 2015 Jan 16. No abstract available.

PMID:
25594539
28.

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

Foijer F, Xie SZ, Simon JE, Bakker PL, Conte N, Davis SH, Kregel E, Jonkers J, Bradley A, Sorger PK.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13427-32. doi: 10.1073/pnas.1400892111. Epub 2014 Sep 2.

29.

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells.

Foijer F, DiTommaso T, Donati G, Hautaviita K, Xie SZ, Heath E, Smyth I, Watt FM, Sorger PK, Bradley A.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2928-33. doi: 10.1073/pnas.1217388110. Epub 2013 Feb 4.

30.

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ.

Cancer Res. 2011 Jul 1;71(13):4608-16. doi: 10.1158/0008-5472.CAN-11-0412. Epub 2011 Jun 28.

31.

CINister thoughts.

Foijer F.

Biochem Soc Trans. 2010 Dec;38(6):1715-21. doi: 10.1042/BST0381715. Review.

PMID:
21118153
32.

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling.

van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, Joenje H, te Riele H.

Genes Dev. 2010 Jul 1;24(13):1377-88. doi: 10.1101/gad.580710. Epub 2010 Jun 15.

33.

Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.

Vormer TL, Foijer F, Wielders CL, te Riele H.

Mol Cell Biol. 2008 Dec;28(24):7263-73. doi: 10.1128/MCB.00313-08. Epub 2008 Oct 20.

34.

Studying chromosome instability in the mouse.

Foijer F, Draviam VM, Sorger PK.

Biochim Biophys Acta. 2008 Sep;1786(1):73-82. doi: 10.1016/j.bbcan.2008.07.004. Epub 2008 Jul 26. Review.

35.

In vivo significance of the G2 restriction point.

Foijer F, Delzenne-Goette E, Dekker M, Te Riele H.

Cancer Res. 2007 Oct 1;67(19):9244-7.

36.

Oncogenic pathways impinging on the G2-restriction point.

Foijer F, Simonis M, van Vliet M, Wessels L, Kerkhoven R, Sorger PK, Te Riele H.

Oncogene. 2008 Feb 14;27(8):1142-54. Epub 2007 Aug 13.

PMID:
17700522
37.
38.

Check, double check: the G2 barrier to cancer.

Foijer F, te Riele H.

Cell Cycle. 2006 Apr;5(8):831-6. Epub 2006 Apr 17. Review.

PMID:
16627998
39.

Mitogen requirement for cell cycle progression in the absence of pocket protein activity.

Foijer F, Wolthuis RM, Doodeman V, Medema RH, te Riele H.

Cancer Cell. 2005 Dec;8(6):455-66. Erratum in: Cancer Cell. 2006 Jan;9(1):71.

40.

Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.

Verlinden L, Eelen G, Beullens I, Van Camp M, Van Hummelen P, Engelen K, Van Hellemont R, Marchal K, De Moor B, Foijer F, Te Riele H, Beullens M, Bollen M, Mathieu C, Bouillon R, Verstuyf A.

J Biol Chem. 2005 Nov 11;280(45):37319-30. Epub 2005 Sep 6.

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