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Items: 14


Genome Editing Using Engineered Nucleases and Their Use in Genomic Screening.

Costa JR, Bejcek BE, McGee JE, Fogel AI, Brimacombe KR, Ketteler R.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2017 Nov 20.


Application of Imaging-Based Assays in Microplate Formats for High-Content Screening.

Fogel AI, Martin SE, Hasson SA.

Methods Mol Biol. 2016;1439:273-304. doi: 10.1007/978-1-4939-3673-1_18.


The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.

Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI, Youle RJ.

Nature. 2015 Aug 20;524(7565):309-314. doi: 10.1038/nature14893. Epub 2015 Aug 12.


MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.

Nezich CL, Wang C, Fogel AI, Youle RJ.

J Cell Biol. 2015 Aug 3;210(3):435-50. doi: 10.1083/jcb.201501002.


Chemogenomic profiling of endogenous PARK2 expression using a genome-edited coincidence reporter.

Hasson SA, Fogel AI, Wang C, MacArthur R, Guha R, Heman-Ackah S, Martin S, Youle RJ, Inglese J.

ACS Chem Biol. 2015 May 15;10(5):1188-97. doi: 10.1021/cb5010417. Epub 2015 Feb 26.


PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.

Kane LA, Lazarou M, Fogel AI, Li Y, Yamano K, Sarraf SA, Banerjee S, Youle RJ.

J Cell Biol. 2014 Apr 28;205(2):143-53. doi: 10.1083/jcb.201402104. Epub 2014 Apr 21.


Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.

Yamano K, Fogel AI, Wang C, van der Bliek AM, Youle RJ.

Elife. 2014 Feb 25;3:e01612. doi: 10.7554/eLife.01612.


Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.

Fogel AI, Dlouhy BJ, Wang C, Ryu SW, Neutzner A, Hasson SA, Sideris DP, Abeliovich H, Youle RJ.

Mol Cell Biol. 2013 Sep;33(18):3675-88. doi: 10.1128/MCB.00079-13. Epub 2013 Jul 22.


Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation.

Fogel AI, Stagi M, Perez de Arce K, Biederer T.

EMBO J. 2011 Sep 16;30(23):4728-38. doi: 10.1038/emboj.2011.336.


SynCAM1, a synaptic adhesion molecule, is expressed in astrocytes and contributes to erbB4 receptor-mediated control of female sexual development.

Sandau US, Mungenast AE, Alderman Z, Sardi SP, Fogel AI, Taylor B, Parent AS, Biederer T, Corfas G, Ojeda SR.

Endocrinology. 2011 Jun;152(6):2364-76. doi: 10.1210/en.2010-1435. Epub 2011 Apr 12.


SynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning.

Robbins EM, Krupp AJ, Perez de Arce K, Ghosh AK, Fogel AI, Boucard A, S├╝dhof TC, Stein V, Biederer T.

Neuron. 2010 Dec 9;68(5):894-906. doi: 10.1016/j.neuron.2010.11.003.


N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.

Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T.

J Biol Chem. 2010 Nov 5;285(45):34864-74. doi: 10.1074/jbc.M110.120865. Epub 2010 Aug 25.


SynCAM 1 participates in axo-dendritic contact assembly and shapes neuronal growth cones.

Stagi M, Fogel AI, Biederer T.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7568-73. doi: 10.1073/pnas.0911798107. Epub 2010 Apr 5.


SynCAMs organize synapses through heterophilic adhesion.

Fogel AI, Akins MR, Krupp AJ, Stagi M, Stein V, Biederer T.

J Neurosci. 2007 Nov 14;27(46):12516-30.

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