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Items: 1 to 50 of 72

1.

The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach.

Wu S, Fagan RR, Uttamapinant C, Lifshitz LM, Fogarty KE, Ting AY, Melikian HE.

J Neurosci. 2017 Sep 27;37(39):9438-9452. doi: 10.1523/JNEUROSCI.3885-16.2017. Epub 2017 Aug 28.

2.

The molecular basis of the genesis of basal tone in internal anal sphincter.

Zhang CH, Wang P, Liu DH, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Lu P, Zheng K, Craige SM, Lifshitz LM, Keaney JF Jr, Fogarty KE, ZhuGe R, Zhu MS.

Nat Commun. 2016 Apr 22;7:11358. doi: 10.1038/ncomms11358.

3.

Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant.

Wu S, Bellve KD, Fogarty KE, Melikian HE.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15480-5. doi: 10.1073/pnas.1512957112. Epub 2015 Nov 30.

4.

A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay.

Kashem MA, Kennedy CA, Fogarty KE, Dimock JR, Zhang Y, Sanville-Ross ML, Skow DJ, Brunette SR, Swantek JL, Hummel HS, Swindle J, Nelson RM.

Assay Drug Dev Technol. 2016 Jan-Feb;14(1):39-49. doi: 10.1089/adt.2015.671. Epub 2015 Oct 1.

PMID:
26426296
5.

Beclin 1 regulates growth factor receptor signaling in breast cancer.

Rohatgi RA, Janusis J, Leonard D, Bellvé KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM.

Oncogene. 2015 Oct 16;34(42):5352-62. doi: 10.1038/onc.2014.454. Epub 2015 Feb 2.

6.

NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone.

Awata J, Takada S, Standley C, Lechtreck KF, Bellvé KD, Pazour GJ, Fogarty KE, Witman GB.

J Cell Sci. 2014 Nov 1;127(Pt 21):4714-27. doi: 10.1242/jcs.155275. Epub 2014 Aug 22.

7.

Catecholamine exocytosis during low frequency stimulation in mouse adrenal chromaffin cells is primarily asynchronous and controlled by the novel mechanism of Ca2+ syntilla suppression.

Lefkowitz JJ, DeCrescenzo V, Duan K, Bellve KD, Fogarty KE, Walsh JV Jr, ZhuGe R.

J Physiol. 2014 Nov 1;592(21):4639-55. doi: 10.1113/jphysiol.2014.278127. Epub 2014 Aug 15.

8.

A high-throughput scintillation proximity assay for sphingosine-1-phosphate lyase.

Kashem MA, Wa C, Wolak JP, Grafos NS, Ryan KR, Sanville-Ross ML, Fogarty KE, Rybina IV, Shoultz A, Molinaro T, Desai SN, Rajan A, Huber JD, Nelson RM.

Assay Drug Dev Technol. 2014 Jun;12(5):293-302. doi: 10.1089/adt.2014.575. Epub 2014 May 20.

PMID:
24846303
9.

Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton.

Gabriel LR, Wu S, Kearney P, Bellvé KD, Standley C, Fogarty KE, Melikian HE.

J Neurosci. 2013 Nov 6;33(45):17836-46. doi: 10.1523/JNEUROSCI.3284-13.2013.

10.

The cellular and molecular basis of bitter tastant-induced bronchodilation.

Zhang CH, Lifshitz LM, Uy KF, Ikebe M, Fogarty KE, ZhuGe R.

PLoS Biol. 2013;11(3):e1001501. doi: 10.1371/journal.pbio.1001501. Epub 2013 Mar 5. Erratum in: PLoS Biol. 2013 Mar;11(3). doi:10.1371/annotation/7899a865-d68b-45bd-8b9b-ec6f50c9308a.

11.

Activation of BK channels may not be required for bitter tastant-induced bronchodilation.

Zhang CH, Chen C, Lifshitz LM, Fogarty KE, Zhu MS, ZhuGe R.

Nat Med. 2012 May 4;18(5):648-50; author reply 650-1. doi: 10.1038/nm.2733. No abstract available.

PMID:
22561814
12.

Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.

Navaroli DM, Bellvé KD, Standley C, Lifshitz LM, Cardia J, Lambright D, Leonard D, Fogarty KE, Corvera S.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):E471-80. doi: 10.1073/pnas.1115495109. Epub 2012 Jan 30.

13.

Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype.

De Crescenzo V, Fogarty KE, Lefkowitz JJ, Bellve KD, Zvaritch E, MacLennan DH, Walsh JV Jr.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):610-5. doi: 10.1073/pnas.1115111108. Epub 2011 Dec 27.

14.

Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes.

Lifshitz LM, Carmichael JD, Lai FA, Sorrentino V, Bellvé K, Fogarty KE, ZhuGe R.

J Gen Physiol. 2011 Aug;138(2):195-209. doi: 10.1085/jgp.201110626. Epub 2011 Jul 11.

15.

Advances in microscopy techniques.

Schmolze DB, Standley C, Fogarty KE, Fischer AH.

Arch Pathol Lab Med. 2011 Feb;135(2):255-63. doi: 10.1043/1543-2165-135.2.255. Review.

PMID:
21284447
16.

A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes.

Zhou QL, Jiang ZY, Mabardy AS, Del Campo CM, Lambright DG, Holik J, Fogarty KE, Straubhaar J, Nicoloro S, Chawla A, Czech MP.

J Biol Chem. 2010 Sep 3;285(36):27581-9. doi: 10.1074/jbc.M110.146886. Epub 2010 Jun 28.

17.

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis.

Nicoli S, Standley C, Walker P, Hurlstone A, Fogarty KE, Lawson ND.

Nature. 2010 Apr 22;464(7292):1196-200. doi: 10.1038/nature08889. Epub 2010 Apr 4. Erratum in: Nature. 2010 Sep 16;467(7313):356.

18.

Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle.

Zhuge R, Bao R, Fogarty KE, Lifshitz LM.

J Biol Chem. 2010 Jan 15;285(3):2203-10. doi: 10.1074/jbc.M109.067546. Epub 2009 Nov 17.

19.

Individual calcium syntillas do not trigger spontaneous exocytosis from nerve terminals of the neurohypophysis.

McNally JM, De Crescenzo V, Fogarty KE, Walsh JV, Lemos JR.

J Neurosci. 2009 Nov 11;29(45):14120-6. doi: 10.1523/JNEUROSCI.1726-09.2009.

20.

Chemokine signaling guides regional patterning of the first embryonic artery.

Siekmann AF, Standley C, Fogarty KE, Wolfe SA, Lawson ND.

Genes Dev. 2009 Oct 1;23(19):2272-7. doi: 10.1101/gad.1813509.

21.

Suppression of Ca2+ syntillas increases spontaneous exocytosis in mouse adrenal chromaffin cells.

Lefkowitz JJ, Fogarty KE, Lifshitz LM, Bellve KD, Tuft RA, ZhuGe R, Walsh JV Jr, De Crescenzo V.

J Gen Physiol. 2009 Oct;134(4):267-80. doi: 10.1085/jgp.200910285.

22.

Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes.

Leonard D, Hayakawa A, Lawe D, Lambright D, Bellve KD, Standley C, Lifshitz LM, Fogarty KE, Corvera S.

J Cell Sci. 2008 Oct 15;121(Pt 20):3445-58. doi: 10.1242/jcs.031484. Epub 2008 Sep 30.

23.

A close association of RyRs with highly dense clusters of Ca2+-activated Cl- channels underlies the activation of STICs by Ca2+ sparks in mouse airway smooth muscle.

Bao R, Lifshitz LM, Tuft RA, Bellvé K, Fogarty KE, ZhuGe R.

J Gen Physiol. 2008 Jul;132(1):145-60. doi: 10.1085/jgp.200709933.

24.

Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance.

Zhang YA, Tuft RA, Lifshitz LM, Fogarty KE, Singer JJ, Zou H.

Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2448-61. Epub 2007 May 4.

25.

Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes.

Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S, Corvera S, Fogarty KE, Czech MP.

Mol Cell Biol. 2007 May;27(9):3456-69. Epub 2007 Mar 5.

26.

Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals.

De Crescenzo V, Fogarty KE, Zhuge R, Tuft RA, Lifshitz LM, Carmichael J, Bellvé KD, Baker SP, Zissimopoulos S, Lai FA, Lemos JR, Walsh JV Jr.

J Neurosci. 2006 Jul 19;26(29):7565-74.

27.

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.

Follit JA, Tuft RA, Fogarty KE, Pazour GJ.

Mol Biol Cell. 2006 Sep;17(9):3781-92. Epub 2006 Jun 14.

28.

Plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells.

Bellve KD, Leonard D, Standley C, Lifshitz LM, Tuft RA, Hayakawa A, Corvera S, Fogarty KE.

J Biol Chem. 2006 Jun 9;281(23):16139-46. Epub 2006 Mar 13.

29.

Syntillas release Ca2+ at a site different from the microdomain where exocytosis occurs in mouse chromaffin cells.

ZhuGe R, DeCrescenzo V, Sorrentino V, Lai FA, Tuft RA, Lifshitz LM, Lemos JR, Smith C, Fogarty KE, Walsh JV Jr.

Biophys J. 2006 Mar 15;90(6):2027-37. Epub 2005 Dec 30.

30.

Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm.

Politz JC, Tuft RA, Prasanth KV, Baudendistel N, Fogarty KE, Lifshitz LM, Langowski J, Spector DL, Pederson T.

Mol Biol Cell. 2006 Mar;17(3):1239-49. Epub 2005 Dec 21.

31.
32.

Using total fluorescence increase (signal mass) to determine the Ca2+ current underlying localized Ca2+ events.

Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ.

J Gen Physiol. 2004 Sep;124(3):259-72. Erratum in: J Gen Physiol. 2005 Nov;126(5):539.

33.

Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them.

Zhuge R, Fogarty KE, Baker SP, McCarron JG, Tuft RA, Lifshitz LM, Walsh JV Jr.

Am J Physiol Cell Physiol. 2004 Dec;287(6):C1577-88. Epub 2004 Aug 11.

34.

Imaging calcium entering the cytosol through a single opening of plasma membrane ion channels: SCCaFTs--fundamental calcium events.

Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ.

Cell Calcium. 2004 Jun;35(6):523-33. Review.

PMID:
15110142
35.

Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity.

Thorn P, Fogarty KE, Parker I.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6774-9. Epub 2004 Apr 16.

36.

Spontaneous mitochondrial depolarizations are independent of SR Ca2+ release.

O'Reilly CM, Fogarty KE, Drummond RM, Tuft RA, Walsh JV Jr.

Am J Physiol Cell Physiol. 2004 May;286(5):C1139-51. Epub 2004 Jan 7.

37.

Ca2+ syntillas, miniature Ca2+ release events in terminals of hypothalamic neurons, are increased in frequency by depolarization in the absence of Ca2+ influx.

De Crescenzo V, ZhuGe R, Velázquez-Marrero C, Lifshitz LM, Custer E, Carmichael J, Lai FA, Tuft RA, Fogarty KE, Lemos JR, Walsh JV Jr.

J Neurosci. 2004 Feb 4;24(5):1226-35.

38.

Quantitative analysis of spontaneous mitochondrial depolarizations.

O'Reilly CM, Fogarty KE, Drummond RM, Tuft RA, Walsh JV Jr.

Biophys J. 2003 Nov;85(5):3350-7.

39.

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria.

Rapizzi E, Pinton P, Szabadkai G, Wieckowski MR, Vandecasteele G, Baird G, Tuft RA, Fogarty KE, Rizzuto R.

J Cell Biol. 2002 Nov 25;159(4):613-24. Epub 2002 Nov 18.

41.

Visualization of Ca2+ entry through single stretch-activated cation channels.

Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ.

Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6404-9.

42.

Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore.

Kidd JF, Pilkington MF, Schell MJ, Fogarty KE, Skepper JN, Taylor CW, Thorn P.

J Biol Chem. 2002 Feb 22;277(8):6504-10. Epub 2001 Nov 27.

43.

The fleet feet of haematopoietic stem cells: rapid motility, interaction and proteopodia.

Frimberger AE, McAuliffe CI, Werme KA, Tuft RA, Fogarty KE, Benoit BO, Dooner MS, Quesenberry PJ.

Br J Haematol. 2001 Mar;112(3):644-54.

PMID:
11260067
44.

Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling.

Chiesa A, Rapizzi E, Tosello V, Pinton P, de Virgilio M, Fogarty KE, Rizzuto R.

Biochem J. 2001 Apr 1;355(Pt 1):1-12. Review.

45.

Relationship of Ca2+ sparks to STOCs studied with 2D and 3D imaging in feline oesophageal smooth muscle cells.

Kirber MT, Etter EF, Bellve KA, Lifshitz LM, Tuft RA, Fay FS, Walsh JV, Fogarty KE.

J Physiol. 2001 Mar 1;531(Pt 2):315-27.

47.

Mechanisms underlying InsP3-evoked global Ca2+ signals in mouse pancreatic acinar cells.

Fogarty KE, Kidd JF, Tuft DA, Thorn P.

J Physiol. 2000 Aug 1;526 Pt 3:515-26.

48.

Microtubules regulate local Ca2+ spiking in secretory epithelial cells.

Fogarty KE, Kidd JF, Turner A, Skepper JN, Carmichael J, Thorn P.

J Biol Chem. 2000 Jul 21;275(29):22487-94.

49.

Intercellular calcium waves in HeLa cells expressing GFP-labeled connexin 43, 32, or 26.

Paemeleire K, Martin PE, Coleman SL, Fogarty KE, Carrington WA, Leybaert L, Tuft RA, Evans WH, Sanderson MJ.

Mol Biol Cell. 2000 May;11(5):1815-27.

50.

A bimodal pattern of InsP(3)-evoked elementary Ca(2+) signals in pancreatic acinar cells.

Fogarty KE, Kidd JF, Tuft RA, Thorn P.

Biophys J. 2000 May;78(5):2298-306.

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