Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 32

1.

A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signaling in monocyte-derived alveolar macrophages.

Joshi N, Watanabe S, Verma R, Jablonski RP, Chen CI, Cheresh P, Markov NS, Reyfman PA, McQuattie-Pimentel AC, Sichizya L, Lu Z, Piseaux R, Kirchenbuechler D, Flozak AS, Gottardi CJ, Cuda CM, Perlman H, Jain M, Kamp DW, Scott Budinger GR, Misharin AV.

Eur Respir J. 2019 Oct 10. pii: 1900646. doi: 10.1183/13993003.00646-2019. [Epub ahead of print]

PMID:
31601718
2.

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.

Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Watanabe S, Williams KJN, Flozak AS, Nicholson TT, Morgan VK, Winter DR, Hinchcliff M, Hrusch CL, Guzy RD, Bonham CA, Sperling AI, Bag R, Hamanaka RB, Mutlu GM, Yeldandi AV, Marshall SA, Shilatifard A, Amaral LAN, Perlman H, Sznajder JI, Argento AC, Gillespie CT, Dematte J, Jain M, Singer BD, Ridge KM, Lam AP, Bharat A, Bhorade SM, Gottardi CJ, Budinger GRS, Misharin AV.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1517-1536. doi: 10.1164/rccm.201712-2410OC.

3.

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions.

Ishiyama N, Sarpal R, Wood MN, Barrick SK, Nishikawa T, Hayashi H, Kobb AB, Flozak AS, Yemelyanov A, Fernandez-Gonzalez R, Yonemura S, Leckband DE, Gottardi CJ, Tepass U, Ikura M.

Nat Commun. 2018 Nov 30;9(1):5121. doi: 10.1038/s41467-018-07481-7.

4.

αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family.

Chiarella SE, Rabin EE, Ostilla LA, Flozak AS, Gottardi CJ.

Tissue Barriers. 2018;6(2):e1463896. doi: 10.1080/21688370.2018.1463896. Epub 2018 May 10. Review.

5.

α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion.

Wood MN, Ishiyama N, Singaram I, Chung CM, Flozak AS, Yemelyanov A, Ikura M, Cho W, Gottardi CJ.

J Cell Biol. 2017 Nov 6;216(11):3767-3783. doi: 10.1083/jcb.201612006. Epub 2017 Sep 5.

6.

Lrp5/β-Catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis.

Sennello JA, Misharin AV, Flozak AS, Berdnikovs S, Cheresh P, Varga J, Kamp DW, Budinger GR, Gottardi CJ, Lam AP.

Am J Respir Cell Mol Biol. 2017 Feb;56(2):191-201. doi: 10.1165/rcmb.2016-0147OC.

7.

A Simple Method to Assess Abundance of the β-Catenin Signaling Pool in Cells.

Flozak AS, Lam AP, Gottardi CJ.

Methods Mol Biol. 2016;1481:49-60. doi: 10.1007/978-1-4939-6393-5_6.

8.

Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling.

Reinke L, Lam AP, Flozak AS, Varga J, Gottardi CJ.

Biochem Biophys Res Commun. 2016 Feb 12;470(3):606-612. doi: 10.1016/j.bbrc.2016.01.097. Epub 2016 Jan 23.

9.

α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.

Escobar DJ, Desai R, Ishiyama N, Folmsbee SS, Novak MN, Flozak AS, Daugherty RL, Mo R, Nanavati D, Sarpal R, Leckband D, Ikura M, Tepass U, Gottardi CJ.

J Cell Sci. 2015 Mar 15;128(6):1150-65. doi: 10.1242/jcs.163824. Epub 2015 Feb 4.

10.

Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.

Lam AP, Herazo-Maya JD, Sennello JA, Flozak AS, Russell S, Mutlu GM, Budinger GR, DasGupta R, Varga J, Kaminski N, Gottardi CJ.

Am J Respir Crit Care Med. 2014 Jul 15;190(2):185-95. doi: 10.1164/rccm.201401-0079OC.

11.

α-Catenin is an inhibitor of transcription.

Daugherty RL, Serebryannyy L, Yemelyanov A, Flozak AS, Yu HJ, Kosak ST, deLanerolle P, Gottardi CJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5260-5. doi: 10.1073/pnas.1308663111. Epub 2014 Mar 25.

12.

Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation.

Lam AP, Flozak AS, Russell S, Wei J, Jain M, Mutlu GM, Budinger GR, Feghali-Bostwick CA, Varga J, Gottardi CJ.

Am J Respir Cell Mol Biol. 2011 Nov;45(5):915-22. doi: 10.1165/rcmb.2010-0113OC. Epub 2011 Mar 31.

13.

Beta-catenin phosphorylated at serine 45 is spatially uncoupled from beta-catenin phosphorylated in the GSK3 domain: implications for signaling.

Maher MT, Mo R, Flozak AS, Peled ON, Gottardi CJ.

PLoS One. 2010 Apr 16;5(4):e10184. doi: 10.1371/journal.pone.0010184.

14.

Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells.

Flozak AS, Lam AP, Russell S, Jain M, Peled ON, Sheppard KA, Beri R, Mutlu GM, Budinger GR, Gottardi CJ.

J Biol Chem. 2010 Jan 29;285(5):3157-67. doi: 10.1074/jbc.M109.070326. Epub 2009 Nov 20.

15.

Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion.

Maher MT, Flozak AS, Stocker AM, Chenn A, Gottardi CJ.

J Cell Biol. 2009 Jul 27;186(2):219-28. doi: 10.1083/jcb.200811108. Epub 2009 Jul 20.

16.

Issues associated with assessing nuclear localization of N-terminally unphosphorylated beta-catenin with monoclonal antibody 8E7.

Maher MT, Flozak AS, Hartsell AM, Russell S, Beri R, Peled ON, Gottardi CJ.

Biol Direct. 2009 Feb 2;4:5. doi: 10.1186/1745-6150-4-5.

19.
20.

Placental expression of insulin-like growth factor receptor-1 and insulin receptor in the growth-restricted fetal rat.

Reid GJ, Flozak AS, Simmons RA.

J Soc Gynecol Investig. 2002 Jul-Aug;9(4):210-4.

PMID:
12113879
21.
22.

Shear stress enhances human endothelial cell wound closure in vitro.

Albuquerque ML, Waters CM, Savla U, Schnaper HW, Flozak AS.

Am J Physiol Heart Circ Physiol. 2000 Jul;279(1):H293-302.

23.

Placental expression of glucose transporter proteins 1 and 3 in growth-restricted fetal rats.

Reid GJ, Lane RH, Flozak AS, Simmons RA.

Am J Obstet Gynecol. 1999 Apr;180(4):1017-23.

PMID:
10203672
24.

Localization and quantification of glucose transporters in liver of growth-retarded fetal and neonatal rats.

Lane RH, Crawford SE, Flozak AS, Simmons RA.

Am J Physiol. 1999 Jan;276(1):E135-42. doi: 10.1152/ajpendo.1999.276.1.E135.

PMID:
9886959
25.

Modulation of glucose transport in fetal rat lung: a sexual dimorphism.

Hart CD, Flozak AS, Simmons RA.

Am J Respir Cell Mol Biol. 1998 Jul;19(1):63-70.

PMID:
9651181
26.

Intrauterine growth retardation alters mitochondrial gene expression and function in fetal and juvenile rat skeletal muscle.

Lane RH, Chandorkar AK, Flozak AS, Simmons RA.

Pediatr Res. 1998 May;43(5):563-70.

PMID:
9585000
27.
28.

Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.

Lane RH, Flozak AS, Ogata ES, Bell GI, Simmons RA.

Pediatr Res. 1996 Mar;39(3):390-4.

PMID:
8929856
29.

The effects of severe maternal diabetes on glucose transport in the fetal rat.

Atkins V, Flozak AS, Ogata ES, Simmons RA.

Endocrinology. 1994 Jul;135(1):409-15.

PMID:
8013378
30.
31.

Glucose regulates glut 1 function and expression in fetal rat lung and muscle in vitro.

Simmons RA, Flozak AS, Ogata ES.

Endocrinology. 1993 Jun;132(6):2312-8.

PMID:
8504736
32.

Supplemental Content

Loading ...
Support Center