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Items: 1 to 50 of 236

1.

Measuring radiologist workload: Progressing from RVUs to study ascribable times.

Pitman A, Cowan IA, Floyd RA, Munro PL.

J Med Imaging Radiat Oncol. 2018 Oct;62(5):605-618. doi: 10.1111/1754-9485.12778. Epub 2018 Aug 2.

PMID:
30070435
2.

Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure.

Du X, West MB, Cai Q, Cheng W, Ewert DL, Li W, Floyd RA, Kopke RD.

Free Radic Biol Med. 2017 Jul;108:627-643. doi: 10.1016/j.freeradbiomed.2017.04.343. Epub 2017 Apr 22.

PMID:
28438658
3.

Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury.

Du X, West MB, Cheng W, Ewert DL, Li W, Saunders D, Towner RA, Floyd RA, Kopke RD.

Oxid Med Cell Longev. 2016;2016:4159357. doi: 10.1155/2016/4159357. Epub 2015 Dec 16.

4.

Antioxidants reduce cellular and functional changes induced by intense noise in the inner ear and cochlear nucleus.

Lu J, Li W, Du X, Ewert DL, West MB, Stewart C, Floyd RA, Kopke RD.

J Assoc Res Otolaryngol. 2014 Jun;15(3):353-72. doi: 10.1007/s10162-014-0441-4. Epub 2014 Feb 5. Erratum in: J Assoc Res Otolaryngol. 2014 Jun;15(3):373-4.

5.

Effects of antioxidant treatment on blast-induced brain injury.

Du X, Ewert DL, Cheng W, West MB, Lu J, Li W, Floyd RA, Kopke RD.

PLoS One. 2013 Nov 5;8(11):e80138. doi: 10.1371/journal.pone.0080138. eCollection 2013.

6.

Therapeutic effects of orally administrated antioxidant drugs on acute noise-induced hearing loss.

Choi CH, Du X, Floyd RA, Kopke RD.

Free Radic Res. 2014 Mar;48(3):264-72. doi: 10.3109/10715762.2013.861599. Epub 2013 Nov 28.

PMID:
24182331
7.

Measuring and managing radiologist workload: measuring radiologist reporting times using data from a Radiology Information System.

Cowan IA, MacDonald SL, Floyd RA.

J Med Imaging Radiat Oncol. 2013 Oct;57(5):558-66. doi: 10.1111/1754-9485.12092. Epub 2013 Jul 12.

PMID:
24119269
8.

Measuring and managing radiologist workload: a method for quantifying radiologist activities and calculating the full-time equivalents required to operate a service.

MacDonald SL, Cowan IA, Floyd RA, Graham R.

J Med Imaging Radiat Oncol. 2013 Oct;57(5):551-7. doi: 10.1111/1754-9485.12091. Epub 2013 Jul 12.

PMID:
24119268
9.

Immuno-spin trapping from biochemistry to medicine: advances, challenges, and pitfalls. Focus on protein-centered radicals.

Gomez-Mejiba SE, Zhai Z, Della-Vedova MC, Muñoz MD, Chatterjee S, Towner RA, Hensley K, Floyd RA, Mason RP, Ramirez DC.

Biochim Biophys Acta. 2014 Feb;1840(2):722-9. doi: 10.1016/j.bbagen.2013.04.039. Epub 2013 May 2. Review.

10.

Nitrone-based therapeutics for neurodegenerative diseases: their use alone or in combination with lanthionines.

Floyd RA, Castro Faria Neto HC, Zimmerman GA, Hensley K, Towner RA.

Free Radic Biol Med. 2013 Sep;62:145-156. doi: 10.1016/j.freeradbiomed.2013.01.033. Epub 2013 Feb 16. Review.

11.

Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.

Towner RA, Gillespie DL, Schwager A, Saunders DG, Smith N, Njoku CE, Krysiak RS 3rd, Larabee C, Iqbal H, Floyd RA, Bourne DW, Abdullah O, Hsu EW, Jensen RL.

Neuro Oncol. 2013 Mar;15(3):330-40. doi: 10.1093/neuonc/nos337. Epub 2013 Jan 17.

12.

The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling.

Zheng X, Gai X, Han S, Moser CD, Hu C, Shire AM, Floyd RA, Roberts LR.

Genes Chromosomes Cancer. 2013 Mar;52(3):225-36. doi: 10.1002/gcc.22022. Epub 2012 Oct 29.

13.

Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment.

Du X, Chen K, Choi CH, Li W, Cheng W, Stewart C, Hu N, Floyd RA, Kopke RD.

Hear Res. 2012 Jan;283(1-2):1-13. doi: 10.1016/j.heares.2011.11.013. Epub 2011 Dec 9.

PMID:
22178982
14.

Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma.

Du X, Choi CH, Chen K, Cheng W, Floyd RA, Kopke RD.

Int J Otolaryngol. 2011;2011:612690. doi: 10.1155/2011/612690. Epub 2011 Sep 25.

15.

Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity.

Mandal MN, Moiseyev GP, Elliott MH, Kasus-Jacobi A, Li X, Chen H, Zheng L, Nikolaeva O, Floyd RA, Ma JX, Anderson RE.

J Biol Chem. 2011 Sep 16;286(37):32491-501. doi: 10.1074/jbc.M111.255877. Epub 2011 Jul 24.

16.

Effects of delayed and extended antioxidant treatment on acute acoustic trauma.

Choi CH, Chen K, Du X, Floyd RA, Kopke RD.

Free Radic Res. 2011 Oct;45(10):1162-72. doi: 10.3109/10715762.2011.605360. Epub 2011 Aug 10.

PMID:
21756051
17.

Anti-cancer activity of nitrones and observations on mechanism of action.

Floyd RA, Chandru HK, He T, Towner R.

Anticancer Agents Med Chem. 2011 May 1;11(4):373-9. Review.

18.

Effects of PBN and OKN007 in rodent glioma models assessed by 1H MR spectroscopy.

He T, Doblas S, Saunders D, Casteel R, Lerner M, Ritchey JW, Snider T, Floyd RA, Towner RA.

Free Radic Biol Med. 2011 Jul 15;51(2):490-502. doi: 10.1016/j.freeradbiomed.2011.04.037. Epub 2011 Apr 30.

PMID:
21600283
19.

Translational research involving oxidative stress and diseases of aging.

Floyd RA, Towner RA, He T, Hensley K, Maples KR.

Free Radic Biol Med. 2011 Sep 1;51(5):931-41. doi: 10.1016/j.freeradbiomed.2011.04.014. Epub 2011 Apr 14. Review.

20.

Comment: identifying optimal initial infusion rates for unfractionated heparin in morbidly obese patients.

Floyd RA.

Ann Pharmacother. 2010 Dec;44(12):2037-8; author reply 2038-9. doi: 10.1345/aph.1P088a. Epub 2010 Nov 23. No abstract available.

PMID:
21098747
21.

Multiparametric assessment of the anti-glioma properties of OKN007 by magnetic resonance imaging.

Garteiser P, Doblas S, Watanabe Y, Saunders D, Hoyle J, Lerner M, He T, Floyd RA, Towner RA.

J Magn Reson Imaging. 2010 Apr;31(4):796-806. doi: 10.1002/jmri.22106.

PMID:
20373422
22.

Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancer.

Floyd RA, Towner RA, Wu D, Abbott A, Cranford R, Branch D, Guo WX, Foster SB, Jones I, Alam R, Moore D, Allen T, Huycke M.

Free Radic Res. 2010 Jan;44(1):108-17. doi: 10.3109/10715760903321796.

23.

Serendipitous findings while researching oxygen free radicals.

Floyd RA.

Free Radic Biol Med. 2009 Apr 15;46(8):1004-13. doi: 10.1016/j.freeradbiomed.2009.02.003. Epub 2009 Feb 12. Review.

24.

In vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGF alpha/c-myc transgenic mouse model.

Griffitts J, Tesiram Y, Reid GE, Saunders D, Floyd RA, Towner RA.

J Lipid Res. 2009 Apr;50(4):611-22. doi: 10.1194/jlr.M800265-JLR200. Epub 2008 Dec 8.

25.

Nitrones as therapeutics.

Floyd RA, Kopke RD, Choi CH, Foster SB, Doblas S, Towner RA.

Free Radic Biol Med. 2008 Nov 15;45(10):1361-74. doi: 10.1016/j.freeradbiomed.2008.08.017. Epub 2008 Aug 29. Review.

26.

Visualization of the protective ability of a free radical trapping compound against rat C6 and F98 gliomas with diffusion tensor fiber tractography.

Asanuma T, Doblas S, Tesiram YA, Saunders D, Cranford R, Yasui H, Inanami O, Smith N, Floyd RA, Kotake Y, Towner RA.

J Magn Reson Imaging. 2008 Sep;28(3):574-87. doi: 10.1002/jmri.21474.

PMID:
18777527
27.

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.

Strong R, Miller RA, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Harrison DE.

Aging Cell. 2008 Oct;7(5):641-50. doi: 10.1111/j.1474-9726.2008.00414.x.

28.

Color and luminance increment thresholds in poor readers.

Dain SJ, Floyd RA, Elliot RT.

Vis Neurosci. 2008 May-Jun;25(3):481-6. doi: 10.1017/S0952523808080565.

PMID:
18598422
29.

Effectiveness of 4-hydroxy phenyl N-tert-butylnitrone (4-OHPBN) alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla.

Choi CH, Chen K, Vasquez-Weldon A, Jackson RL, Floyd RA, Kopke RD.

Free Radic Biol Med. 2008 May 1;44(9):1772-84. doi: 10.1016/j.freeradbiomed.2008.02.005. Epub 2008 Feb 20.

PMID:
18328271
30.

Phenyl-tert-butylnitrone induces tumor regression and decreases angiogenesis in a C6 rat glioma model.

Doblas S, Saunders D, Kshirsagar P, Pye Q, Oblander J, Gordon B, Kosanke S, Floyd RA, Towner RA.

Free Radic Biol Med. 2008 Jan 1;44(1):63-72. Epub 2007 Sep 20.

PMID:
18045548
31.

Modulation of Fas-FasL related apoptosis by PBN in the early phases of choline deficient diet-mediated hepatocarcinogenesis in rats.

Inoue Y, Asanuma T, Smith N, Saunders D, Oblander J, Kotake Y, Floyd RA, Towner RA.

Free Radic Res. 2007 Sep;41(9):972-80.

PMID:
17729114
32.

An Aging Interventions Testing Program: study design and interim report.

Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Strong R.

Aging Cell. 2007 Aug;6(4):565-75. Epub 2007 Jun 18. Erratum in: Aging Cell. 2008 Jun;7(3):445.

33.

LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period.

Asada K, Kotake Y, Asada R, Saunders D, Broyles RH, Towner RA, Fukui H, Floyd RA.

J Biomed Biotechnol. 2006;2006(1):17142.

34.
35.

Nitrones as therapeutics in age-related diseases.

Floyd RA.

Aging Cell. 2006 Feb;5(1):51-7. Review.

36.

Nitric oxide production by primary liver cells isolated from amino acid diet-fed rats.

Kotake Y, Kishida H, Nakae D, Floyd RA.

Methods Enzymol. 2005;396:535-41.

PMID:
16291260
37.

Methylene blue photoinactivation abolishes West Nile virus infectivity in vivo.

Papin JF, Floyd RA, Dittmer DP.

Antiviral Res. 2005 Nov;68(2):84-7. Epub 2005 Aug 9.

PMID:
16118025
38.

Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes.

Guo WX, Pye QN, Williamson KS, Stewart CA, Hensley KL, Kotake Y, Floyd RA, Broyles RH.

Free Radic Biol Med. 2005 Sep 1;39(5):641-50.

PMID:
16085182
39.

Distinct patterns of gene expression in hepatocellular carcinomas and adjacent non-cancerous, cirrhotic liver tissues in rats fed a choline-deficient, L-amino acid-defined diet.

Uematsu F, Takahashi M, Yoshida M, Igarashi M, Watanabe N, Suzuki N, Abe M, Rusyn I, Floyd RA, Nakae D.

Cancer Sci. 2005 Jul;96(7):414-24.

40.

Sensitivity of protein tyrosine phosphatase activity to the redox environment, cytochrome C, and microperoxidase.

Salsman SJ, Hensley K, Floyd RA.

Antioxid Redox Signal. 2005 Jul-Aug;7(7-8):1078-88.

PMID:
15998263
41.

Oxidative modification of proteins in cell signaling.

Hensley K, Floyd RA.

Antioxid Redox Signal. 2005 May-Jun;7(5-6):523-5. No abstract available.

PMID:
15889997
42.

Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, Hatch GE, Hensley K, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ 2nd, Rokach J, Shigenaga MK, Sohal RS, Sun J, Tice RR, Van Thiel DH, Wellner D, Walter PB, Tomer KB, Mason RP, Barrett JC.

Free Radic Biol Med. 2005 Mar 15;38(6):698-710.

PMID:
15721980
43.

Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke.

Maples KR, Green AR, Floyd RA.

CNS Drugs. 2004;18(15):1071-84. Review.

PMID:
15581379
44.

The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.

West M, Mhatre M, Ceballos A, Floyd RA, Grammas P, Gabbita SP, Hamdheydari L, Mai T, Mou S, Pye QN, Stewart C, West S, Williamson KS, Zemlan F, Hensley K.

J Neurochem. 2004 Oct;91(1):133-43.

45.

Reactive oxygen species in choline deficiency-induced apoptosis in rat hepatocytes.

Guo WX, Pye QN, Williamson KS, Stewart CA, Hensley KL, Kotake Y, Floyd RA, Broyles RH.

Free Radic Biol Med. 2004 Oct 1;37(7):1081-9.

PMID:
15336324
46.

Anti-inflammatory effects of tocopherol metabolites.

Grammas P, Hamdheydari L, Benaksas EJ, Mou S, Pye QN, Wechter WJ, Floyd RA, Stewart C, Hensley K.

Biochem Biophys Res Commun. 2004 Jul 2;319(3):1047-52.

PMID:
15184087
47.

Methylene blue photoinactivation of RNA viruses.

Floyd RA, Schneider JE Jr, Dittmer DP.

Antiviral Res. 2004 Mar;61(3):141-51. Review.

PMID:
15168794
48.
49.

Inhibition of the development of hepatocellular carcinomas by phenyl N-tert-butyl nitrone in rats fed with a choline-deficient, L-amino acid-defined diet.

Nakae D, Uematsu F, Kishida H, Kusuoka O, Katsuda S, Yoshida M, Takahashi M, Maekawa A, Denda A, Konishi Y, Kotake Y, Floyd RA.

Cancer Lett. 2004 Mar 31;206(1):1-13.

PMID:
15019154
50.

New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine.

Hensley K, Benaksas EJ, Bolli R, Comp P, Grammas P, Hamdheydari L, Mou S, Pye QN, Stoddard MF, Wallis G, Williamson KS, West M, Wechter WJ, Floyd RA.

Free Radic Biol Med. 2004 Jan 1;36(1):1-15. Review.

PMID:
14732286

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