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Items: 1 to 50 of 355

1.

Pharmacological PAR-1 inhibition reduces blood glucose levels but does not improve kidney function in experimental type 2 diabetic nephropathy.

Waasdorp M, Florquin S, Duitman J, Spek CA.

FASEB J. 2019 Jul 9:fj201900516R. doi: 10.1096/fj.201900516R. [Epub ahead of print]

PMID:
31287960
2.

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.

Scantlebery AML, Uil M, Butter LM, Poelman R, Claessen N, Girardin SE, Florquin S, Roelofs JJTH, Leemans JC.

PLoS One. 2019 Mar 25;14(3):e0214437. doi: 10.1371/journal.pone.0214437. eCollection 2019.

3.

A multicenter application of the 2018 Banff Classification for BK polyomavirus-associated nephropathy in renal transplantation.

Bouatou Y, Nguyen TQ, Roelofs JJTH, Bemelman FJ, Michielsen L, Goldschmeding R, Kers J, Florquin S.

Transplantation. 2019 Mar 21. doi: 10.1097/TP.0000000000002712. [Epub ahead of print]

PMID:
30896679
4.

Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis.

de Porto APNA, Claushuis TAM, van der Donk LEH, de Beer R, de Boer OJ, Florquin S, Roelofs JJTH, Hendriks RW, van der Poll T, Van't Veer C, de Vos AF.

Thromb Haemost. 2019 Jun;119(6):930-940. doi: 10.1055/s-0039-1681046. Epub 2019 Mar 14.

PMID:
30873567
5.

Histological characteristics of Acute Tubular Injury during Delayed Graft Function predict renal function after renal transplantation.

Pieters TT, Falke LL, Nguyen TQ, Verhaar MC, Florquin S, Bemelman FJ, Kers J, Vanhove T, Kuypers D, Goldschmeding R, Rookmaaker MB.

Physiol Rep. 2019 Mar;7(5):e14000. doi: 10.14814/phy2.14000.

6.

Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain.

Uil M, Scantlebery AML, Butter LM, Larsen PWB, de Boer OJ, Leemans JC, Florquin S, Roelofs JJTH.

Sci Rep. 2019 Feb 27;9(1):3425. doi: 10.1038/s41598-018-38075-4.

7.

Challenges and opportunities for nephrology in Western Europe.

Rondeau E, Luyckx VA, Anders HJ, Eckardt KU, Florquin S, Marti HP, Ølgaard K, Harden P; members of the Western Europe Regional Board, International Society of Nephrology.

Kidney Int. 2019 May;95(5):1037-1040. doi: 10.1016/j.kint.2018.09.028. Epub 2019 Feb 16. No abstract available.

PMID:
30777285
8.

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia.

de Porto AP, Liu Z, de Beer R, Florquin S, de Boer OJ, Hendriks RW, van der Poll T, de Vos AF.

Mol Med. 2019 Jan 15;25(1):3. doi: 10.1186/s10020-018-0069-7.

9.

Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection.

Emal D, Rampanelli E, Claessen N, Bemelman FJ, Leemans JC, Florquin S, Dessing MC.

Sci Rep. 2019 Jan 14;9(1):106. doi: 10.1038/s41598-018-37482-x.

10.

Evaluation of the current post-transplantation Human Leukocyte Antigen antibody screening in pediatric renal transplant recipients.

Demirok A, Ranzijn C, Lardy J, Florquin S, Bouts A.

Pediatr Transplant. 2019 Mar;23(2):e13338. doi: 10.1111/petr.13338. Epub 2019 Jan 11.

PMID:
30635959
11.

Urinary mitochondrial deoxyribonucleic acid associates with delayed graft function following renal transplantation.

Jansen MPB, Pulskens WPC, Uil M, Claessen N, Nieuwenhuizen G, Standaar D, Hau CM, Nieuwland R, Florquin S, Bemelman FJ, Leemans JC, Roelofs JJTH.

Nephrol Dial Transplant. 2018 Dec 24. doi: 10.1093/ndt/gfy372. [Epub ahead of print]

PMID:
30590723
12.

Protease-activated receptor-1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy.

Waasdorp M, de Rooij DM, Florquin S, Duitman J, Spek CA.

J Cell Mol Med. 2019 Feb;23(2):1268-1279. doi: 10.1111/jcmm.14028. Epub 2018 Nov 28.

13.

Early Steroid Withdrawal Compared With Standard Immunosuppression in Kidney Transplantation - Interim Analysis of the Amsterdam-Leiden-Groningen Randomized Controlled Trial.

van Sandwijk MS, de Vries APJ, Bakker SJL, Ten Berge IJM, Berger SP, Bouatou YR, de Fijter JW, Florquin S, Homan van der Heide JJ, Idu MM, Krikke C, van der Pant KAMI, Reinders ME, Ringers J, van der Weerd NC, Bemelman FJ, Sanders JS.

Transplant Direct. 2018 May 15;4(6):e354. doi: 10.1097/TXD.0000000000000794. eCollection 2018 Jun.

14.

Erratum: Protease activated receptor 2 in diabetic nephropathy: a double edged sword.

Waasdorp M, Duitman JW, Florquin S, Spek CA.

Am J Transl Res. 2018 Jul 15;10(7):2220. eCollection 2018.

15.

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney.

Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC.

J Pathol. 2018 Dec;246(4):470-484. doi: 10.1002/path.5150. Epub 2018 Nov 5.

PMID:
30073645
16.

Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice.

Waasdorp M, Duitman J, Florquin S, Spek CA.

Oncotarget. 2018 Apr 24;9(31):21655-21662. doi: 10.18632/oncotarget.25069. eCollection 2018 Apr 24.

17.

The role of platelets in acute kidney injury.

Jansen MPB, Florquin S, Roelofs JJTH.

Nat Rev Nephrol. 2018 Jul;14(7):457-471. doi: 10.1038/s41581-018-0015-5. Review.

PMID:
29760447
18.

S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy.

Tammaro A, Florquin S, Brok M, Claessen N, Butter LM, Teske GJD, de Boer OJ, Vogl T, Leemans JC, Dessing MC.

Clin Exp Immunol. 2018 Sep;193(3):361-375. doi: 10.1111/cei.13154.

19.

Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain.

Uil M, Scantlebery AML, Butter LM, Larsen PWB, de Boer OJ, Leemans JC, Florquin S, Roelofs JJTH.

Sci Rep. 2018 Apr 3;8(1):5542. doi: 10.1038/s41598-018-23839-9. Erratum in: Sci Rep. 2019 Feb 27;9(1):3425.

20.

No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction.

Stroo I, Emal D, Butter LM, Teske GJ, Claessen N, Dessing MC, Girardin SE, Florquin S, Leemans JC.

BMC Nephrol. 2018 Apr 2;19(1):78. doi: 10.1186/s12882-018-0867-8.

21.

[A Massive Open Oneline Course (MOOC) on pratical histology: A goal, a tool, a large public ! Return on a first experience].

Multon S, Pesesse L, Weatherspoon A, Florquin S, Van de Poel JF, Martin P, Vincke G, Hoyoux R, Marée R, Verpoorten D, Bonnet P, Quatresooz P, Defaweux V.

Ann Pathol. 2018 Apr;38(2):76-84. doi: 10.1016/j.annpat.2018.02.002. Epub 2018 Mar 21. French.

22.

Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.

Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC.

Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1883-1895. doi: 10.1016/j.bbadis.2018.03.003. Epub 2018 Mar 4.

23.

Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy.

Bouatou Y, Stokman G, Claessen N, Roelofs JJTH, Bemelman F, Kers J, Florquin S.

Transpl Immunol. 2018 Apr;47:18-21. doi: 10.1016/j.trim.2017.12.005. Epub 2018 Jan 2.

24.

CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.

Eymael J, Sharma S, Loeven MA, Wetzels JF, Mooren F, Florquin S, Deegens JK, Willemsen BK, Sharma V, van Kuppevelt TH, Bakker MA, Ostendorf T, Moeller MJ, Dijkman HB, Smeets B, van der Vlag J.

Kidney Int. 2018 Mar;93(3):626-642. doi: 10.1016/j.kint.2017.09.020. Epub 2017 Dec 21.

PMID:
29276101
25.

Protease activated receptor 2 in diabetic nephropathy: a double edged sword.

Waasdorp M, Duitman J, Florquin S, Spek CA, Spek AC.

Am J Transl Res. 2017 Oct 15;9(10):4512-4520. eCollection 2017. Erratum in: Am J Transl Res. 2018 Jul 15;10(7):2220. Spek AC [corrected to Spek CA].

26.

ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice.

van Lieshout MHP, de Vos AF, Dessing MC, de Porto APNA, de Boer OJ, de Beer R, Terpstra S, Florquin S, Van't Veer C, van der Poll T.

Eur J Immunol. 2018 Jan;48(1):66-79. doi: 10.1002/eji.201646554. Epub 2017 Nov 3.

27.

Diagnostic accuracy of immunofluorescence versus immunoperoxidase staining to distinguish immune complex-mediated glomerulonephritis and C3 dominant glomerulopathy.

Bouatou Y, Kers J, Chevalier-Florquin MSN, Claessen N, Nguyen TQ, Damman J, Proença H, Roelofs JJTH, Florquin S.

Histopathology. 2018 Mar;72(4):601-608. doi: 10.1111/his.13385. Epub 2017 Dec 22.

PMID:
28881045
28.

Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction.

Jansen MPB, Pulskens WP, Butter LM, Florquin S, Juffermans NP, Roelofs JJTH, Leemans JC.

Shock. 2018 Mar;49(3):301-310. doi: 10.1097/SHK.0000000000000967.

PMID:
28837526
29.

High glucose induces HGF-independent activation of Met receptor in human renal tubular epithelium.

Mesarosova L, Ochodnicky P, Leemans JC, Florquin S, Krenek P, Klimas J.

J Recept Signal Transduct Res. 2017 Dec;37(6):535-542. doi: 10.1080/10799893.2017.1365902. Epub 2017 Aug 18.

PMID:
28819999
30.

Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis.

García-Laorden MI, Stroo I, Terpstra S, Florquin S, Medema JP, van T Veer C, de Vos AF, van der Poll T.

Mediators Inflamm. 2017;2017:4137563. doi: 10.1155/2017/4137563. Epub 2017 Jun 12.

31.

Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy.

Ochodnicky P, Lattenist L, Ahdi M, Kers J, Uil M, Claessen N, Leemans JC, Florquin S, Meijers JCM, Gerdes VEA, Roelofs JJTH.

Am J Pathol. 2017 Sep;187(9):1971-1983. doi: 10.1016/j.ajpath.2017.05.004. Epub 2017 Jun 29.

PMID:
28668213
32.

NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity.

Stokman G, Kors L, Bakker PJ, Rampanelli E, Claessen N, Teske GJD, Butter L, van Andel H, van den Bergh Weerman MA, Larsen PWB, Dessing MC, Zuurbier CJ, Girardin SE, Florquin S, Leemans JC.

J Exp Med. 2017 Aug 7;214(8):2405-2420. doi: 10.1084/jem.20161031. Epub 2017 Jun 16.

33.

Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation.

Rampanelli E, Orsó E, Ochodnicky P, Liebisch G, Bakker PJ, Claessen N, Butter LM, van den Bergh Weerman MA, Florquin S, Schmitz G, Leemans JC.

Sci Rep. 2017 Jun 6;7(1):2861. doi: 10.1038/s41598-017-01994-9.

34.

Absence of Intragraft B Cells in Rejection Biopsies After Rituximab Induction Therapy: Consequences for Clinical Outcome.

van den Hoogen MW, Steenbergen EJ, Baas MC, Florquin S, Hilbrands LB.

Transplant Direct. 2017 Mar 10;3(4):e143. doi: 10.1097/TXD.0000000000000659. eCollection 2017 Apr.

35.

Diagnostic dilemmas in a girl with acute glomerulonephritis: Questions.

Falix FA, Oosterveld MJS, Florquin S, Groothoff JW, Bouts AHM.

Pediatr Nephrol. 2018 Jan;33(1):63-64. doi: 10.1007/s00467-017-3625-4. Epub 2017 Mar 20. No abstract available.

36.

Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation.

Tammaro A, Kers J, Emal D, Stroo I, Teske GJ, Butter LM, Claessen N, Damman J, Derive M, Navis GJ, Florquin S, Leemans JC, Dessing MC.

Sci Rep. 2017 Mar 15;7:44163. doi: 10.1038/srep44163. No abstract available.

37.

Diagnostic dilemmas in a girl with acute glomerulonephritis: Answers.

Falix FA, Oosterveld MJS, Florquin S, Groothoff JW, Bouts AHM.

Pediatr Nephrol. 2018 Jan;33(1):65-69. doi: 10.1007/s00467-017-3626-3. Epub 2017 Mar 9. No abstract available.

38.

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives.

Tammaro A, Derive M, Gibot S, Leemans JC, Florquin S, Dessing MC.

Pharmacol Ther. 2017 Sep;177:81-95. doi: 10.1016/j.pharmthera.2017.02.043. Epub 2017 Feb 27. Review.

39.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB.

PLoS One. 2017 Feb 24;12(2):e0168981. doi: 10.1371/journal.pone.0168981. eCollection 2017.

40.

A chlorhexidine-releasing epoxy-based coating on titanium implants prevents Staphylococcus aureus experimental biomaterial-associated infection.

Riool M, Dirks AJ, Jaspers V, de Boer L, Loontjens TJ, van der Loos CM, Florquin S, Apachitei I, Rijk LN, Keul HA, Zaat SA.

Eur Cell Mater. 2017 Feb 14;33:143-157. doi: 10.22203/eCM.v033a11.

41.

A novel mutation of laminin β2 (LAMB2) in two siblings with renal failure.

Falix FA, Bennebroek CA, van der Zwaag B, Lapid-Gortzak R, Florquin S, Oosterveld MJ.

Eur J Pediatr. 2017 Apr;176(4):515-519. doi: 10.1007/s00431-017-2871-6. Epub 2017 Feb 10.

42.

Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia.

Anas AA, Claushuis TAM, Mohan RA, Christoffels VM, Aidinis V, Florquin S, Van't Veer C, Hou B, de Vos AF, van der Poll T.

Am J Respir Cell Mol Biol. 2017 May;56(5):648-656. doi: 10.1165/rcmb.2016-0190OC.

PMID:
28187270
43.

Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation.

Tammaro A, Kers J, Emal D, Stroo I, Teske GJD, Butter LM, Claessen N, Damman J, Derive M, Navis GJ, Florquin S, Leemans JC, Dessing MC.

Sci Rep. 2016 Dec 8;6:38275. doi: 10.1038/srep38275. Erratum in: Sci Rep. 2017 Mar 15;7:44163.

44.

Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury.

Emal D, Rampanelli E, Stroo I, Butter LM, Teske GJ, Claessen N, Stokman G, Florquin S, Leemans JC, Dessing MC.

J Am Soc Nephrol. 2017 May;28(5):1450-1461. doi: 10.1681/ASN.2016030255. Epub 2016 Dec 7.

45.

Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation.

Dessing MC, Kers J, Damman J, Navis GJ, Florquin S, Leemans JC.

Sci Rep. 2016 Nov 7;6:36315. doi: 10.1038/srep36315.

46.

Early Conversion to Prednisolone/Everolimus as an Alternative Weaning Regimen Associates With Beneficial Renal Transplant Histology and Function: The Randomized-Controlled MECANO Trial.

Bemelman FJ, de Fijter JW, Kers J, Meyer C, Peters-Sengers H, de Maar EF, van der Pant KA, de Vries AP, Sanders JS, Zwinderman A, Idu MM, Berger S, Reinders ME, Krikke C, Bajema IM, van Dijk MC, Ten Berge IJ, Ringers J, Lardy J, Roelen D, Moes DJ, Florquin S, Homan van der Heide JJ.

Am J Transplant. 2017 Apr;17(4):1020-1030. doi: 10.1111/ajt.14048. Epub 2016 Oct 17.

47.

Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps.

Jansen MP, Emal D, Teske GJ, Dessing MC, Florquin S, Roelofs JJ.

Kidney Int. 2017 Feb;91(2):352-364. doi: 10.1016/j.kint.2016.08.006. Epub 2016 Sep 28.

PMID:
27692564
48.

Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice.

Waasdorp M, Duitman J, Florquin S, Spek CA.

Sci Rep. 2016 Sep 13;6:33030. doi: 10.1038/srep33030.

49.

Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus.

van der Meer AJ, Achouiti A, van der Ende A, Soussan AA, Florquin S, de Vos A, Zeerleder SS, van der Poll T.

Mol Med. 2016 Sep;22:292-299. doi: 10.2119/molmed.2015.00242. Epub 2016 Jun 24.

50.

Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism.

Anas AA, van Lieshout MH, Claushuis TA, de Vos AF, Florquin S, de Boer OJ, Hou B, Van't Veer C, van der Poll T.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L219-28. doi: 10.1152/ajplung.00078.2016. Epub 2016 Jun 10.

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