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Items: 1 to 50 of 173

1.

Toward the elimination of bias in Pediatric Research.

Bearer C, Agostoni C, Anand KJS, Ambalavanan N, Bhandari V, Bliss JM, Bloomfield F, Bonifacio SL, Buhimschi I, Cilio MR, Coppes M, Czinn SJ, El-Khuffash A, Embleton N, Felderhoff-Müser U, Ferriero DM, Florin T, Fuentes-Afflick E, Gardner W, Gospe SM Jr, Gunn A, Gressens P, Guissani D, Haiden N, Hauptman M, Kim KS, Klebanoff M, Lachman P, Lanphear B, Ozen S, Roehr C, Roland D, Rosenblum N, Schwarz M, Staiano A, Stroustrup A, Valente EM, Wilson-Costello D, Wynn J, Molloy E.

Pediatr Res. 2019 Sep 18. doi: 10.1038/s41390-019-0583-5. [Epub ahead of print] No abstract available.

PMID:
31533126
2.

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity.

Sheng YH, Wong KY, Seim I, Wang R, He Y, Wu A, Patrick M, Lourie R, Schreiber V, Giri R, Ng CP, Popat A, Hooper J, Kijanka G, Florin TH, Begun J, Radford KJ, Hasnain S, McGuckin MA.

Oncogene. 2019 Aug 19. doi: 10.1038/s41388-019-0951-y. [Epub ahead of print]

PMID:
31427737
3.

Factors Associated With Antibiotic Prescribing and Outcomes for Pediatric Pneumonia in the Emergency Department.

Lipshaw MJ, Florin TA, Krueger S, Belsky MA, Epperson T, Crotty EJ, Lipscomb J, Jacobs J, Rattan MS, Ruddy RM, Shah SS, Ambroggio L.

Pediatr Emerg Care. 2019 Jul 8. doi: 10.1097/PEC.0000000000001892. [Epub ahead of print]

PMID:
31290801
4.

Validation of the British Thoracic Society Severity Criteria for Pediatric Community-acquired Pneumonia.

Ambroggio L, Brokamp C, Mantyla R, DePaoli B, Ruddy RM, Shah SS, Florin TA.

Pediatr Infect Dis J. 2019 Sep;38(9):894-899. doi: 10.1097/INF.0000000000002380.

PMID:
31232897
5.

Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: a retrospective analysis.

Jamal A, Finkelstein Y, Kuppermann N, Freedman SB, Florin TA, Babl FE, Dalziel SR, Zemek R, Plint AC, Steele DW, Schnadower D, Johnson DW, Stephens D, Kharbanda A, Roland D, Lyttle MD, Macias CG, Fernandes RM, Benito J, Schuh S; Pediatric Emergency Research Networks.

Lancet Child Adolesc Health. 2019 Aug;3(8):539-547. doi: 10.1016/S2352-4642(19)30193-2. Epub 2019 Jun 7.

PMID:
31182422
6.

Health and climate change.

Florin TH, Allen DW.

Lancet. 2019 Jun 1;393(10187):2196-2197. doi: 10.1016/S0140-6736(19)30303-4. No abstract available.

PMID:
31162074
7.

Diagnostic Testing and Antibiotic Use in Young Children With Community-Acquired Pneumonia in the United States, 2008-2015.

Florin TA, Byczkowski T, Gerber JS, Ruddy R, Kuppermann N.

J Pediatric Infect Dis Soc. 2019 May 20. pii: piz026. doi: 10.1093/jpids/piz026. [Epub ahead of print]

PMID:
31107533
8.

Improving Risk Stratification for Children with Pneumonia: The Journey Continues.

Florin TA.

Clin Infect Dis. 2019 May 6. pii: ciz353. doi: 10.1093/cid/ciz353. [Epub ahead of print] No abstract available.

PMID:
31056638
9.

Guideline Adherence in Diagnostic Testing and Treatment of Community-Acquired Pneumonia in Children.

McLaren SH, Mistry RD, Neuman MI, Florin TA, Dayan PS.

Pediatr Emerg Care. 2019 Feb 14. doi: 10.1097/PEC.0000000000001745. [Epub ahead of print]

PMID:
30829848
10.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, Cole AT, Cummings FR, Daly MJ, Ellul P, Fedorak RN, Festen EAM, Florin TH, Gaya DR, Halfvarson J, Hart AL, Heerasing NM, Hendy P, Irving PM, Jones SE, Koskela J, Lindsay JO, Mansfield JC, McGovern D, Parkes M, Pollok RCG, Ramakrishnan S, Rampton DS, Rivas MA, Russell RK, Schultz M, Sebastian S, Seksik P, Singh A, So K, Sokol H, Subramaniam K, Todd A, Annese V, Weersma RK, Xavier R, Ward R, Weedon MN, Goodhand JR, Kennedy NA, Ahmad T; IBD Pharmacogenetics Study Group.

JAMA. 2019 Feb 26;321(8):773-785. doi: 10.1001/jama.2019.0709. Erratum in: JAMA. 2019 Apr 23;321(16):1636.

11.

Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children: The PRIME Randomized Clinical Trial.

Frey TM, Florin TA, Caruso M, Zhang N, Zhang Y, Mittiga MR.

JAMA Pediatr. 2019 Feb 1;173(2):140-146. doi: 10.1001/jamapediatrics.2018.4582.

PMID:
30592476
12.

Clinical Risk Factors for Revisits for Children With Community-Acquired Pneumonia.

Ambroggio L, Herman H, Fain E, Huang G, Florin TA.

Hosp Pediatr. 2018 Nov;8(11):718-723. doi: 10.1542/hpeds.2018-0014.

13.

A well-tolerated and rapidly acting thiopurine for IBD?

Florin THJ, Wright JD, Jambhrunkar SD, Henman MG, Popat A.

Drug Discov Today. 2019 Jan;24(1):37-41. doi: 10.1016/j.drudis.2018.09.001. Epub 2018 Sep 7. Review.

PMID:
30196006
14.

Predicting Escalated Care in Infants With Bronchiolitis.

Freire G, Kuppermann N, Zemek R, Plint AC, Babl FE, Dalziel SR, Freedman SB, Atenafu EG, Stephens D, Steele DW, Fernandes RM, Florin TA, Kharbanda A, Lyttle MD, Johnson DW, Schnadower D, Macias CG, Benito J, Schuh S; Pediatric Emergency Research Networks (PERN).

Pediatrics. 2018 Sep;142(3). pii: e20174253. doi: 10.1542/peds.2017-4253. Epub 2018 Aug 20. Erratum in: Pediatrics. 2019 Feb;143(2):.

15.

Emergency Medical Services Utilization Is Associated With Community Deprivation in Children.

Riney LC, Brokamp C, Beck AF, Pomerantz WJ, Schwartz HP, Florin TA.

Prehosp Emerg Care. 2019 Mar-Apr;23(2):225-232. doi: 10.1080/10903127.2018.1501124. Epub 2018 Aug 17.

PMID:
30118621
16.

Factors Associated With Pneumonia Severity in Children: A Systematic Review.

Dean P, Florin TA.

J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):323-334. doi: 10.1093/jpids/piy046.

17.

Entyvio lengthen dose-interval study: lengthening vedolizumab dose interval and the risk of clinical relapse in inflammatory bowel disease.

Chan W, Lynch N, Bampton P, Chang J, Chung A, Florin T, Hetzel DJ, Jakobovits S, Moore G, Pavli P, Radford-Smith G, Thin L, Baraty B, Haifer C, Yau Y, Leong RWL.

Eur J Gastroenterol Hepatol. 2018 Jul;30(7):735-740. doi: 10.1097/MEG.0000000000001150.

PMID:
29727386
18.

The role of IL-22 in the resolution of sterile and nonsterile inflammation.

Alabbas SY, Begun J, Florin TH, Oancea I.

Clin Transl Immunology. 2018 Apr 18;7(4):e1017. doi: 10.1002/cti2.1017. eCollection 2018. Review.

19.

Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site.

Pantel L, Florin T, Dobosz-Bartoszek M, Racine E, Sarciaux M, Serri M, Houard J, Campagne JM, de Figueiredo RM, Midrier C, Gaudriault S, Givaudan A, Lanois A, Forst S, Aumelas A, Cotteaux-Lautard C, Bolla JM, Vingsbo Lundberg C, Huseby DL, Hughes D, Villain-Guillot P, Mankin AS, Polikanov YS, Gualtieri M.

Mol Cell. 2018 Apr 5;70(1):83-94.e7. doi: 10.1016/j.molcel.2018.03.001.

20.

Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease.

Wright EK, Kamm MA, De Cruz P, Hamilton AL, Selvaraj F, Princen F, Gorelik A, Liew D, Prideaux L, Lawrance IC, Andrews JM, Bampton PA, Jakobovits SL, Florin TH, Gibson PR, Debinski H, Macrae FA, Samuel D, Kronborg I, Radford-Smith G, Gearry RB, Selby W, Bell SJ, Brown SJ, Connell WR.

J Crohns Colitis. 2018 May 25;12(6):653-661. doi: 10.1093/ecco-jcc/jjy003.

PMID:
29385469
21.

Validation of the Pediatric Infectious Diseases Society-Infectious Diseases Society of America Severity Criteria in Children With Community-Acquired Pneumonia.

Florin TA, Brokamp C, Mantyla R, DePaoli B, Ruddy R, Shah SS, Ambroggio L.

Clin Infect Dis. 2018 Jun 18;67(1):112-119. doi: 10.1093/cid/ciy031.

22.

Clinical examination not strongly associated with pneumonia diagnosis.

Florin TA.

J Pediatr. 2018 Jan;192:266-269. doi: 10.1016/j.jpeds.2017.10.059. No abstract available.

PMID:
29246352
23.

Accounting for misclassification bias of binary outcomes due to underscreening: a sensitivity analysis.

Zhang N, Cheng S, Ambroggio L, Florin TA, Macaluso M.

BMC Med Res Methodol. 2017 Dec 12;17(1):168. doi: 10.1186/s12874-017-0447-9.

24.

Practice Variation in Acute Bronchiolitis: A Pediatric Emergency Research Networks Study.

Schuh S, Babl FE, Dalziel SR, Freedman SB, Macias CG, Stephens D, Steele DW, Fernandes RM, Zemek R, Plint AC, Florin TA, Lyttle MD, Johnson DW, Gouin S, Schnadower D, Klassen TP, Bajaj L, Benito J, Kharbanda A, Kuppermann N; Pediatric Emergency Research Networks (PERN).

Pediatrics. 2017 Dec;140(6). pii: e20170842. doi: 10.1542/peds.2017-0842.

25.

Colonic thioguanine pro-drug: Investigation of microbiome and novel host metabolism.

Florin T, Movva R, Begun J, Duley J, Oancea I, Cuív PÓ.

Gut Microbes. 2018 Mar 4;9(2):175-178. doi: 10.1080/19490976.2017.1387343. Epub 2017 Oct 17.

26.

Reliability of Examination Findings in Suspected Community-Acquired Pneumonia.

Florin TA, Ambroggio L, Brokamp C, Rattan MS, Crotty EJ, Kachelmeyer A, Ruddy RM, Shah SS.

Pediatrics. 2017 Sep;140(3). pii: e20170310. doi: 10.1542/peds.2017-0310.

27.

Critical assessment of thioguanine treatment for inflammatory bowel diseases: Is it time to rehabilitate this treatment?

Movva R, Haywood A, Khan SA, Florin TH, Oancea I.

J Dig Dis. 2017 Sep;18(9):529-536. doi: 10.1111/1751-2980.12536. Review.

PMID:
28834232
28.

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.

Florin T, Maracci C, Graf M, Karki P, Klepacki D, Berninghausen O, Beckmann R, Vázquez-Laslop N, Wilson DN, Rodnina MV, Mankin AS.

Nat Struct Mol Biol. 2017 Sep;24(9):752-757. doi: 10.1038/nsmb.3439. Epub 2017 Jul 24.

29.

Emerging Biomarkers of Illness Severity: Urinary Metabolites Associated with Sepsis and Necrotizing Methicillin-Resistant Staphylococcus aureus Pneumonia.

Ambroggio L, Florin TA, Shah SS, Ruddy R, Yeomans L, Trexel J, Stringer KA.

Pharmacotherapy. 2017 Sep;37(9):1033-1042. doi: 10.1002/phar.1973. Epub 2017 Jul 28.

30.

Emergency Department Management of Bronchiolitis in the United States.

Gong C, Byczkowski T, McAneney C, Goyal MK, Florin TA.

Pediatr Emerg Care. 2019 May;35(5):323-329. doi: 10.1097/PEC.0000000000001145.

PMID:
28441240
31.

Procalcitonin in Childhood Pneumonia.

Shah SS, Florin TA, Ambroggio L.

J Pediatric Infect Dis Soc. 2018 Feb 19;7(1):54-55. doi: 10.1093/jpids/piw095. No abstract available.

PMID:
28339955
32.

Is Tachycardia at Discharge From the Pediatric Emergency Department a Cause for Concern? A Nonconcurrent Cohort Study.

Wilson PM, Florin TA, Huang G, Fenchel M, Mittiga MR.

Ann Emerg Med. 2017 Sep;70(3):268-276.e2. doi: 10.1016/j.annemergmed.2016.12.010. Epub 2017 Feb 24.

PMID:
28238501
33.

Serologic antibodies in relation to outcome in postoperative Crohn's disease.

Hamilton AL, Kamm MA, De Cruz P, Wright EK, Selvaraj F, Princen F, Gorelik A, Liew D, Lawrance IC, Andrews JM, Bampton PA, Sparrow MP, Florin TH, Gibson PR, Debinski H, Gearry RB, Macrae FA, Leong RW, Kronborg I, Radford-Smith G, Selby W, Bell SJ, Brown SJ, Connell WR.

J Gastroenterol Hepatol. 2017 Jun;32(6):1195-1203. doi: 10.1111/jgh.13677.

PMID:
27976801
34.

Viral bronchiolitis.

Florin TA, Plint AC, Zorc JJ.

Lancet. 2017 Jan 14;389(10065):211-224. doi: 10.1016/S0140-6736(16)30951-5. Epub 2016 Aug 20. Review.

PMID:
27549684
35.

Microbial metabolism of thiopurines: A method to measure thioguanine nucleotides.

Movva R, Lobb M, Ó Cuív P, Florin THJ, Duley JA, Oancea I.

J Microbiol Methods. 2016 Sep;128:102-107. doi: 10.1016/j.mimet.2016.07.017. Epub 2016 Jul 19.

PMID:
27444548
36.

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism.

Oancea I, Movva R, Das I, Aguirre de Cárcer D, Schreiber V, Yang Y, Purdon A, Harrington B, Proctor M, Wang R, Sheng Y, Lobb M, Lourie R, Ó Cuív P, Duley JA, Begun J, Florin TH.

Gut. 2017 Jan;66(1):59-69. doi: 10.1136/gutjnl-2015-310874. Epub 2016 Jul 13.

37.

MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target.

Sheng YH, He Y, Hasnain SZ, Wang R, Tong H, Clarke DT, Lourie R, Oancea I, Wong KY, Lumley JW, Florin TH, Sutton P, Hooper JD, McMillan NA, McGuckin MA.

Oncogene. 2017 Feb 2;36(5):700-713. doi: 10.1038/onc.2016.241. Epub 2016 Jul 11.

38.

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.

Gulhane M, Murray L, Lourie R, Tong H, Sheng YH, Wang R, Kang A, Schreiber V, Wong KY, Magor G, Denman S, Begun J, Florin TH, Perkins A, Cuív PÓ, McGuckin MA, Hasnain SZ.

Sci Rep. 2016 Jun 28;6:28990. doi: 10.1038/srep28990.

39.

Pneumonia in Children Presenting to the Emergency Department With an Asthma Exacerbation.

Florin TA, Carron H, Huang G, Shah SS, Ruddy R, Ambroggio L.

JAMA Pediatr. 2016 Aug 1;170(8):803-5. doi: 10.1001/jamapediatrics.2016.0310. No abstract available.

40.

Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis.

Overmann KM, Florin TA.

Evid Based Med. 2016 Aug;21(4):143. doi: 10.1136/ebmed-2016-110452. Epub 2016 May 24. No abstract available.

PMID:
27222561
41.

Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.

Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS, Steitz TA.

Nucleic Acids Res. 2016 Mar 18;44(5):2439-50. doi: 10.1093/nar/gkw018. Epub 2016 Jan 24.

42.

Reply.

Florin TA, Aronson PL, Neuman MI.

J Pediatr. 2016 Apr;171:320-1. doi: 10.1016/j.jpeds.2015.12.049. Epub 2016 Jan 13. No abstract available.

PMID:
26794468
43.

Emergency Department Use of Computed Tomography for Children with Ventricular Shunts.

Florin TA, Aronson PL, Hall M, Kharbanda AB, Shah SS, Freedman SB, Alpern ER, Mistry RD, Simon HK, Berry J, Coley BD, Neuman MI.

J Pediatr. 2015 Dec;167(6):1382-8.e2. doi: 10.1016/j.jpeds.2015.09.024. Epub 2015 Oct 23.

PMID:
26474707
44.

Biomarkers for Predicting Illness Severity in Children With Acute Lower Respiratory Tract Infections.

Shah SS, Ambroggio L, Florin TA.

J Pediatric Infect Dis Soc. 2015 Sep;4(3):189-91. doi: 10.1093/jpids/piu041. Epub 2014 May 14. No abstract available.

45.

Efficacy of thiopurines and adalimumab in preventing Crohn's disease recurrence in high-risk patients - a POCER study analysis.

De Cruz P, Kamm MA, Hamilton AL, Ritchie KJ, Krejany EO, Gorelik A, Liew D, Prideaux L, Lawrance IC, Andrews JM, Bampton PA, Jakobovits S, Florin TH, Gibson PR, Debinski H, Gearry RB, Macrae FA, Leong RW, Kronborg I, Radford-Smith G, Selby W, Johnston MJ, Woods R, Elliott PR, Bell SJ, Brown SJ, Connell WR, Desmond PV.

Aliment Pharmacol Ther. 2015 Oct;42(7):867-79. doi: 10.1111/apt.13353. Epub 2015 Aug 28.

46.

Letter: therapeutic trial is more informative than SeHCAT to diagnose bile acid malabsorption.

Hendy P, Florin T.

Aliment Pharmacol Ther. 2015 Sep;42(6):780. doi: 10.1111/apt.13320. No abstract available.

47.

Protein synthesis by ribosomes with tethered subunits.

Orelle C, Carlson ED, Szal T, Florin T, Jewett MC, Mankin AS.

Nature. 2015 Aug 6;524(7563):119-24. doi: 10.1038/nature14862. Epub 2015 Jul 29.

PMID:
26222032
48.

Geographic Variation in Hospitalization for Lower Respiratory Tract Infections Across One County.

Beck AF, Florin TA, Campanella S, Shah SS.

JAMA Pediatr. 2015 Sep;169(9):846-54. doi: 10.1001/jamapediatrics.2015.1148.

49.

Enteroliths in a Kock continent ileostomy: case report and review of the literature.

Moattar H, Begun J, Florin T.

Endoscopy. 2015;47 Suppl 1 UCTN:E200-1. doi: 10.1055/s-0034-1391302. Epub 2015 Jun 10. Review. No abstract available.

PMID:
26062147
50.

Successful Pregnancies with Thiopurine-Allopurinol Co-Therapy for Inflammatory Bowel Disease.

Sheikh M, Nelson-Piercy C, Duley J, Florin T, Ansari A.

J Crohns Colitis. 2015 Aug;9(8):680-4. doi: 10.1093/ecco-jcc/jjv072. Epub 2015 May 4.

PMID:
25939351

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