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Items: 46

1.

The alveolar immune cell landscape is dysregulated in checkpoint inhibitor pneumonitis.

Suresh K, Naidoo J, Zhong Q, Xiong Y, Mammen J, de Flores MV, Cappelli L, Balaji A, Palmer T, Forde PM, Anagnostou V, Ettinger DS, Marrone KA, Kelly RJ, Hann CL, Levy B, Feliciano JL, Lin CT, Feller-Kopman D, Lerner AD, Lee H, Shafiq M, Yarmus L, Lipson EJ, Soloski M, Brahmer JR, Danoff SK, D'Alessio F.

J Clin Invest. 2019 Jul 16;130:4305-4315. doi: 10.1172/JCI128654.

2.

A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation.

Oehlers SH, Flores MV, Hall CJ, Wang L, Ko DC, Crosier KE, Crosier PS.

FEBS J. 2017 Feb;284(3):402-413. doi: 10.1111/febs.13976. Epub 2017 Jan 9.

3.

An in vivo antilymphatic screen in zebrafish identifies novel inhibitors of mammalian lymphangiogenesis and lymphatic-mediated metastasis.

Astin JW, Jamieson SM, Eng TC, Flores MV, Misa JP, Chien A, Crosier KE, Crosier PS.

Mol Cancer Ther. 2014 Oct;13(10):2450-62. doi: 10.1158/1535-7163.MCT-14-0469-T. Epub 2014 Jul 22.

4.

Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production.

Hall CJ, Boyle RH, Astin JW, Flores MV, Oehlers SH, Sanderson LE, Ellett F, Lieschke GJ, Crosier KE, Crosier PS.

Cell Metab. 2013 Aug 6;18(2):265-78. doi: 10.1016/j.cmet.2013.06.018.

5.

Modeling of celiac disease immune response and the therapeutic effect of potential drugs.

Demin OO, Smirnov SV, Sokolov VV, Cucurull-Sanchez L, Pichardo-Almarza C, Flores MV, Benson N, Demin OV.

BMC Syst Biol. 2013 Jul 5;7:56. doi: 10.1186/1752-0509-7-56.

6.

Pharmacokinetics and safety in cynomolgus monkeys of a monoclonal antibody targeting human scavenger receptor class B type-1 for hepatitis C treatment.

Flores MV, Corbau RG, Guionaud S.

Antivir Ther. 2013;18(6):775-84. doi: 10.3851/IMP2570. Epub 2013 May 23.

PMID:
23702590
7.

Chemically induced intestinal damage models in zebrafish larvae.

Oehlers SH, Flores MV, Hall CJ, Okuda KS, Sison JO, Crosier KE, Crosier PS.

Zebrafish. 2013 Jun;10(2):184-93. doi: 10.1089/zeb.2012.0824. Epub 2013 Feb 28.

PMID:
23448252
8.

lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish.

Okuda KS, Astin JW, Misa JP, Flores MV, Crosier KE, Crosier PS.

Development. 2012 Jul;139(13):2381-91. doi: 10.1242/dev.077701. Epub 2012 May 23.

9.

Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis.

Oehlers SH, Flores MV, Hall CJ, Crosier KE, Crosier PS.

Dis Model Mech. 2012 Jul;5(4):457-67. doi: 10.1242/dmm.009365. Epub 2012 Apr 19.

10.

Preclinical studies of PF-04849285, an interferon-α8 fusion protein for the treatment of HCV.

Flores MV, Hickling TP, Sreckovic S, Fidock MD, Horscroft N, Katragadda M, Savic B, Rawal J, Delpuech-Adams OE, Robas N, Corey T, Nelms L, Lawton M, Marcek J, Stubbs M, Westby M, Ciaramella G.

Antivir Ther. 2012;17(5):869-81. doi: 10.3851/IMP2099. Epub 2012 Apr 13. Erratum in: Antivir Ther.2012;17(5):939.

PMID:
22505586
11.

Infection-responsive expansion of the hematopoietic stem and progenitor cell compartment in zebrafish is dependent upon inducible nitric oxide.

Hall CJ, Flores MV, Oehlers SH, Sanderson LE, Lam EY, Crosier KE, Crosier PS.

Cell Stem Cell. 2012 Feb 3;10(2):198-209. doi: 10.1016/j.stem.2012.01.007.

12.

The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish.

Oehlers SH, Flores MV, Hall CJ, Swift S, Crosier KE, Crosier PS.

Dis Model Mech. 2011 Nov;4(6):832-41. doi: 10.1242/dmm.006122. Epub 2011 Jul 4.

13.

A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents.

Oehlers SH, Flores MV, Okuda KS, Hall CJ, Crosier KE, Crosier PS.

Dev Dyn. 2011 Jan;240(1):288-98. doi: 10.1002/dvdy.22519.

14.

Topographical distribution of antimicrobial genes in the zebrafish intestine.

Oehlers SH, Flores MV, Chen T, Hall CJ, Crosier KE, Crosier PS.

Dev Comp Immunol. 2011 Mar;35(3):385-91. doi: 10.1016/j.dci.2010.11.008. Epub 2010 Nov 25.

PMID:
21093479
15.

Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.

Brimacombe CL, Grove J, Meredith LW, Hu K, Syder AJ, Flores MV, Timpe JM, Krieger SE, Baumert TF, Tellinghuisen TL, Wong-Staal F, Balfe P, McKeating JA.

J Virol. 2011 Jan;85(1):596-605. doi: 10.1128/JVI.01592-10. Epub 2010 Oct 20.

16.

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties.

Flores MV, Crawford KC, Pullin LM, Hall CJ, Crosier KE, Crosier PS.

Biochem Biophys Res Commun. 2010 Sep 10;400(1):164-8. doi: 10.1016/j.bbrc.2010.08.037. Epub 2010 Aug 13.

PMID:
20709024
17.

Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies.

Flores MV, Hall CJ, Crosier KE, Crosier PS.

Dev Dyn. 2010 Jul;239(7):2128-35. doi: 10.1002/dvdy.22328.

18.

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells.

Lam EY, Hall CJ, Crosier PS, Crosier KE, Flores MV.

Blood. 2010 Aug 12;116(6):909-14. doi: 10.1182/blood-2010-01-264382. Epub 2010 May 7.

PMID:
20453160
19.

Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation.

Oehlers SH, Flores MV, Hall CJ, O'Toole R, Swift S, Crosier KE, Crosier PS.

Dev Comp Immunol. 2010 Mar;34(3):352-9. doi: 10.1016/j.dci.2009.11.007. Epub 2009 Dec 1.

PMID:
19941893
20.

HCV-NS3 inhibitors: determination of their kinetic parameters and mechanism.

Flores MV, Strawbridge J, Ciaramella G, Corbau R.

Biochim Biophys Acta. 2009 Oct;1794(10):1441-8. doi: 10.1016/j.bbapap.2009.06.004. Epub 2009 Jun 6.

PMID:
19505593
21.

Live cell imaging of zebrafish leukocytes.

Hall C, Flores MV, Crosier K, Crosier P.

Methods Mol Biol. 2009;546:255-71. doi: 10.1007/978-1-60327-977-2_16.

PMID:
19378109
22.

Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages.

Hall C, Flores MV, Chien A, Davidson A, Crosier K, Crosier P.

J Leukoc Biol. 2009 May;85(5):751-65. doi: 10.1189/jlb.0708405. Epub 2009 Feb 13.

PMID:
19218482
23.

Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors.

Lam EY, Chau JY, Kalev-Zylinska ML, Fountaine TM, Mead RS, Hall CJ, Crosier PS, Crosier KE, Flores MV.

Blood. 2009 Feb 5;113(6):1241-9. doi: 10.1182/blood-2008-04-149898. Epub 2008 Oct 16.

PMID:
18927441
24.

Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2.

Flores MV, Hall CJ, Davidson AJ, Singh PP, Mahagaonkar AA, Zon LI, Crosier KE, Crosier PS.

Gastroenterology. 2008 Nov;135(5):1665-75. doi: 10.1053/j.gastro.2008.07.024. Epub 2008 Jul 31.

PMID:
18804112
25.

Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae.

Cvejic A, Hall C, Bak-Maier M, Flores MV, Crosier P, Redd MJ, Martin P.

J Cell Sci. 2008 Oct 1;121(Pt 19):3196-206. doi: 10.1242/jcs.032235. Epub 2008 Sep 9.

26.

Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish.

Flores MV, Lam EY, Crosier KE, Crosier PS.

Nat Cell Biol. 2008 Mar;10(3):346-52. doi: 10.1038/ncb1697. Epub 2008 Feb 3.

PMID:
18246063
27.

The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish.

Hall C, Flores MV, Storm T, Crosier K, Crosier P.

BMC Dev Biol. 2007 May 4;7:42.

28.

The zebrafish retinoid-related orphan receptor (ror) gene family.

Flores MV, Hall C, Jury A, Crosier K, Crosier P.

Gene Expr Patterns. 2007 Apr;7(5):535-43. Epub 2007 Feb 13.

PMID:
17374568
29.
30.

An essential role for zebrafish Fgfrl1 during gill cartilage development.

Hall C, Flores MV, Murison G, Crosier K, Crosier P.

Mech Dev. 2006 Dec;123(12):925-40. Epub 2006 Aug 24.

31.

Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements.

Flores MV, Tsang VW, Hu W, Kalev-Zylinska M, Postlethwait J, Crosier P, Crosier K, Fisher S.

Gene Expr Patterns. 2004 Sep;4(5):573-81.

PMID:
15261836
32.

Runx3 is required for hematopoietic development in zebrafish.

Kalev-Zylinska ML, Horsfield JA, Flores MV, Postlethwait JH, Chau JY, Cattin PM, Vitas MR, Crosier PS, Crosier KE.

Dev Dyn. 2003 Nov;228(3):323-36.

33.

Radar is required for the establishment of vascular integrity in the zebrafish.

Hall CJ, Flores MV, Davidson AJ, Crosier KE, Crosier PS.

Dev Biol. 2002 Nov 1;251(1):105-17.

34.

Pathways in blood and vessel development revealed through zebrafish genetics.

Crosier PS, Kalev-Zylinska ML, Hall CJ, Flores MV, Horsfield JA, Crosier KE.

Int J Dev Biol. 2002;46(4):493-502. Review.

35.

Influence of glucose solubility and dissolution rate on the kinetics of lipase catalyzed synthesis of glucose laurate in 2-methyl 2-butanol.

Flores MV, Naraghi K, Engasser JM, Halling PJ.

Biotechnol Bioeng. 2002 Jun 30;78(7):815-21.

PMID:
12001174
36.

Full model for reversible kinetics of lipase-catalyzed sugar-ester synthesis in 2-methyl 2-butanol.

Flores MV, Halling PJ.

Biotechnol Bioeng. 2002 Jun 30;78(7):795-801.

PMID:
12001171
37.

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

Kalev-Zylinska ML, Horsfield JA, Flores MV, Postlethwait JH, Vitas MR, Baas AM, Crosier PS, Crosier KE.

Development. 2002 Apr;129(8):2015-30.

38.

Critical Micelle Concentrations of Nonionic Surfactants in Organic Solvents: Approximate Prediction with UNIFAC.

Flores MV, Voutsas EC, Spiliotis N, Eccleston GM, Bell G, Tassios DP, Halling PJ.

J Colloid Interface Sci. 2001 Aug 1;240(1):277-283.

PMID:
11446811
39.

The nature of fatty acid modifies the equilibrium position in the esterification catalyzed by lipase.

Flores MV, Sewalt JJ, Janssen AE, van der Padt A.

Biotechnol Bioeng. 2000 Feb 5;67(3):364-71.

PMID:
10620267
40.

The proteolytic system of the yeast Kluyveromyces lactis.

Flores MV, Cuellas A, Voget CE.

Yeast. 1999 Oct;15(14):1437-48.

41.

Antimalarial antisense activity of hexitol nucleic acids.

Flores MV, Atkins D, Stewart TS, van Aerschot A, Herdewijn P.

Parasitol Res. 1999 Oct;85(10):864-6.

PMID:
10494816
42.

Plasmodium falciparum: a microassay for the malarial carbamoyl phosphate synthetase.

Flores MV, Stewart TS.

Exp Parasitol. 1998 Mar;88(3):243-5. No abstract available.

PMID:
9562429
43.

Inhibition of Plasmodium falciparum proliferation in vitro by ribozymes.

Flores MV, Atkins D, Wade D, O'Sullivan WJ, Stewart TS.

J Biol Chem. 1997 Jul 4;272(27):16940-5.

44.

Long-term cultivation of Plasmodium falciparum in media with commercial non-serum supplements.

Flores MV, Berger-Eiszele SM, Stewart TS.

Parasitol Res. 1997;83(7):734-6.

PMID:
9272569
45.

Characterisation of the carbamoyl phosphate synthetase gene from Plasmodium falciparum.

Flores MV, O'Sullivan WJ, Stewart TS.

Mol Biochem Parasitol. 1994 Dec;68(2):315-8. No abstract available.

PMID:
7739677
46.

A simple method for the purification of mitochondrial DNA from Plasmodium falciparum.

Flores MV, Stewart TS, O'Sullivan WJ.

Int J Parasitol. 1991 Sep;21(5):605-8.

PMID:
1743858

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