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Items: 37

1.

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey.

Karas Kuželički N, Prodan Žitnik I, Gurwitz D, Llerena A, Cascorbi I, Siest S, Simmaco M, Ansari M, Pazzagli M, Di Resta C, Brandslund I, Schwab M, Vermeersch P, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Stingl JC, van Schaik RH, Manolopoulos VG, Marc J; Pharmacogenomics Education Working Group (PGxEWG); European Society of Pharmacogenomics and Personalized Therapy (ESPT).

Pharmacogenomics. 2019 Jun;20(9):643-657. doi: 10.2217/pgs-2019-0009.

2.

Intramyocardial thrombin promotes angiogenesis and improves cardiac function in an experimental rabbit model of acute myocardial infarction.

Mitsos S, Koletsis EN, Katsanos K, Bravou V, Kolonitsiou F, Marinos E, Flordellis CS, Dougenis D.

J Thorac Cardiovasc Surg. 2014 Apr;147(4):1376-83. doi: 10.1016/j.jtcvs.2013.05.036. Epub 2013 Jul 13.

3.

Editorial: From structural plasticity to functional diversity of 7TMRs: biased agonism and beyond.

Flordellis CS.

Curr Pharm Des. 2012;18(2):119-20. No abstract available.

PMID:
22250770
4.
5.

Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients.

Katsakiori PF, Papapetrou EP, Goumenos DS, Nikiforidis GC, Flordellis CS.

Indian J Pharmacol. 2011 Jul;43(4):385-8. doi: 10.4103/0253-7613.83106.

6.

Investigation of clinical interaction between omeprazole and tacrolimus in CYP3A5 non-expressors, renal transplant recipients.

Katsakiori PF, Papapetrou EP, Goumenos DS, Nikiforidis GC, Flordellis CS.

Ther Clin Risk Manag. 2010 Jun 24;6:265-9.

7.

Factors affecting the long-term response to tacrolimus in renal transplant patients: pharmacokinetic and pharmacogenetic approach.

Katsakiori PF, Papapetrou EP, Sakellaropoulos GC, Goumenos DS, Nikiforidis GC, Flordellis CS.

Int J Med Sci. 2010 May 11;7(2):94-100.

8.

Lack of association between the cholesteryl ester transfer protein gene--TaqIB polymorphism and coronary restenosis following percutaneous transluminal coronary angioplasty and stenting: a pilot study.

Kaestner S, Patsouras N, Spathas DH, Flordellis CS, Manolis AS.

Angiology. 2010 May;61(4):338-43. doi: 10.1177/0003319709348297. Epub 2009 Oct 8.

PMID:
19815603
9.

Identification of single-nucleotide polymorphisms by the oligonucleotide ligation reaction: a DNA biosensor for simultaneous visual detection of both alleles.

Toubanaki DK, Christopoulos TK, Ioannou PC, Flordellis CS.

Anal Chem. 2009 Jan 1;81(1):218-24. doi: 10.1021/ac801870x.

PMID:
19055390
10.

High-throughput chemiluminometric genotyping of single nucleotide polymorphisms of histamine, serotonin, and adrenergic receptor genes.

Toubanaki DK, Christopoulos TK, Ioannou PC, Flordellis CS.

Anal Biochem. 2009 Feb 1;385(1):34-41. doi: 10.1016/j.ab.2008.10.032. Epub 2008 Oct 31.

PMID:
19026982
11.

Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of angiogenesis.

Zania P, Gourni D, Aplin AC, Nicosia RF, Flordellis CS, Maragoudakis ME, Tsopanoglou NE.

J Pharmacol Exp Ther. 2009 Feb;328(2):378-89. doi: 10.1124/jpet.108.145664. Epub 2008 Nov 6.

PMID:
18988770
12.

Thrombin mediates mitogenesis and survival of human endothelial cells through distinct mechanisms.

Zania P, Papaconstantinou M, Flordellis CS, Maragoudakis ME, Tsopanoglou NE.

Am J Physiol Cell Physiol. 2008 May;294(5):C1215-26. doi: 10.1152/ajpcell.00452.2007. Epub 2008 Mar 26.

13.

Statins and the risk of colorectal cancer: a meta-analysis of 18 studies involving more than 1.5 million patients.

Bonovas S, Filioussi K, Flordellis CS, Sitaras NM.

J Clin Oncol. 2007 Aug 10;25(23):3462-8.

PMID:
17687150
14.

Alpha 2-adrenergic receptors decrease DNA replication and cell proliferation and induce neurite outgrowth in transfected rat pheochromocytoma cells.

Karkoulias G, Mastrogianni O, Ilias I, Lymperopoulos A, Taraviras S, Tsopanoglou N, Sitaras N, Flordellis CS.

Ann N Y Acad Sci. 2006 Nov;1088:335-45.

PMID:
17192578
15.

Rethinking target discovery in polygenic diseases.

Flordellis CS, Manolis AS, Paris H, Karabinis A.

Curr Top Med Chem. 2006;6(16):1791-8. Review.

PMID:
17017957
16.

Methylene blue inhibits angiogenesis in chick chorioallontoic membrane through a nitric oxide-independent mechanism.

Zacharakis N, Tone P, Flordellis CS, Maragoudakis ME, Tsopanoglou NE.

J Cell Mol Med. 2006 Apr-Jun;10(2):493-8.

17.

Lack of association between alpha2B-adrenergic receptor polymorphism and risk of restenosis following coronary angioplasty and stent implantation--preliminary report.

Manolis AS, Patsouras N, Ilias I, Constantakopoulos J, Pyriohou A, Lymperopoulos A, Spathas DH, Flordellis CS.

Clin Chem Lab Med. 2006;44(7):807-12.

PMID:
16776624
18.

Alpha2-adrenergic receptor subtype-specific activation of NF-kappaB in PC12 cells.

Lymperopoulos A, Karkoulias G, Koch WJ, Flordellis CS.

Neurosci Lett. 2006 Jul 24;402(3):210-5. Epub 2006 May 24.

PMID:
16730120
19.

Blockade of angiogenesis by small molecule antagonists to protease-activated receptor-1: association with endothelial cell growth suppression and induction of apoptosis.

Zania P, Kritikou S, Flordellis CS, Maragoudakis ME, Tsopanoglou NE.

J Pharmacol Exp Ther. 2006 Jul;318(1):246-54. Epub 2006 Apr 4.

PMID:
16595737
20.

The emergence of a new paradigm of pharmacogenomics.

Flordellis CS.

Pharmacogenomics. 2005 Jul;6(5):515-26.

PMID:
16014001
21.

New therapeutic options for the metabolic syndrome: what's next?

Flordellis CS, Ilias I, Papavassiliou AG.

Trends Endocrinol Metab. 2005 Aug;16(6):254-60. Review.

PMID:
16002303
22.

Thrombin functions through its RGD sequence in a non-canonical conformation.

Papaconstantinou ME, Carrell CJ, Pineda AO, Bobofchak KM, Mathews FS, Flordellis CS, Maragoudakis ME, Tsopanoglou NE, Di Cera E.

J Biol Chem. 2005 Aug 19;280(33):29393-6. Epub 2005 Jul 5.

23.

Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education.

Gurwitz D, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Kirchheiner J, Licinio J, Llerena A, Manolopoulos VG, Sheffield LJ, Siest G, Torricelli F, Vasiliou V, Wong S.

Pharmacogenomics J. 2005;5(4):221-5.

PMID:
15852053
24.

On the mode of action of thrombin-induced angiogenesis: thrombin peptide, TP508, mediates effects in endothelial cells via alphavbeta3 integrin.

Tsopanoglou NE, Papaconstantinou ME, Flordellis CS, Maragoudakis ME.

Thromb Haemost. 2004 Oct;92(4):846-57.

PMID:
15467917
25.

The shift in the "paradigm" of the pharmacology of hypertension.

Flordellis CS, Goumenos D, Kourounis G, Tsementzis SA, Paris H, Vlachojiannis J.

Curr Top Med Chem. 2004;4(4):487-98. Review.

PMID:
14965315
26.

The alpha2B adrenergic receptor deletion/insertion polymorphism in morbid obesity.

Sykiotis GP, Polyzogopoulou E, Georgopoulos NA, Trakada G, Spyropoulos K, Kalfarentzos F, Papavassiliou AG, Vagenakis AG, Flordellis CS.

Clin Auton Res. 2003 Jun;13(3):203-7.

PMID:
12822042
27.

Oral administration of recombinant human granulocyte macrophage colony-stimulating factor in the management of radiotherapy-induced esophagitis.

Koukourakis MI, Flordellis CS, Giatromanolaki A, Koukouraki S, Kapsoritakis A, Potamianos S, Retalis G, Sivridis E, Salsaa B, Harris AL, Maragoudakis MI.

Clin Cancer Res. 1999 Dec;5(12):3970-6.

28.

Alpha 2 adrenergic receptor subtypes expressed in Chinese hamster ovary cells activate differentially mitogen-activated protein kinase by a p21ras independent pathway.

Flordellis CS, Berguerand M, Gouache P, Barbu V, Gavras H, Handy DE, Béréziat G, Masliah J.

J Biol Chem. 1995 Feb 24;270(8):3491-4.

29.

Diverse tissue expression of rat alpha 2-adrenergic receptor genes.

Handy DE, Flordellis CS, Bogdanova NN, Bresnahan MR, Gavras H.

Hypertension. 1993 Jun;21(6 Pt 1):861-5.

PMID:
7684725
30.

Cloning and expression of a rat brain alpha 2B-adrenergic receptor.

Flordellis CS, Handy DE, Bresnahan MR, Zannis VI, Gavras H.

Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):1019-23.

31.

Expression of multiple alpha 2-adrenergic receptor messenger RNA species in rat tissues.

Flordellis CS, Castellano M, Franco R, Zannis VI, Gavras H.

Hypertension. 1990 Jun;15(6 Pt 2):881-7.

PMID:
2161794
32.

High level of expression of functional human platelet alpha 2-adrenergic receptors in a stable mouse C127 cell line.

Bresnahan MR, Flordellis CS, Vassilatis DK, Makrides SC, Zannis VI, Gavras H.

Biochim Biophys Acta. 1990 May 22;1052(3):439-45.

PMID:
1972337
33.

Analysis of the cellular proto-oncogene mht/raf: relationship to the 5' sequences of v-mht in avian carcinoma virus MH2 and v-raf in murine sarcoma virus 3611.

Flordellis CS, Kan NC, Lautenberger JA, Samuel KP, Garon CF, Papas TS.

Virology. 1985 Mar;141(2):267-74.

PMID:
3002017
34.
35.

A common onc gene sequence transduced by avian carcinoma virus MH2 and by murine sarcoma virus 3611.

Kan NC, Flordellis CS, Mark GE, Duesberg PH, Papas TS.

Science. 1984 Feb 24;223(4638):813-6.

PMID:
6320371
36.

Ultrastructural studies of fibroblasts transfected with hepatitis B virus DNA.

Aoki N, Gerber MA, Thung SN, Chen ML, Christman JK, Price PM, Flordellis CS, Acs G.

Hepatology. 1984 Jan-Feb;4(1):84-9.

PMID:
6363250
37.

Avian carcinoma virus MH2 contains a transformation-specific sequence, mht, and shares the myc sequence with MC29, CMII, and OK10 viruses.

Kan NC, Flordellis CS, Garon CF, Duesberg PH, Papas TS.

Proc Natl Acad Sci U S A. 1983 Nov;80(21):6566-70.

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