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Items: 1 to 50 of 273

1.

Predictors of One Year Compliance with Adaptive Servo-Ventilation in Patients with Heart Failure and Sleep- Disordered Breathing: Preliminary Data from the ADVENT-HF Trial.

Perger E, Lyons OD, Inami T, Smith S, Floras JS, Logan AG, Douglas Bradley T; ADVENT-HF Investigators.

Eur Respir J. 2018 Nov 8. pii: 1801626. doi: 10.1183/13993003.01626-2018. [Epub ahead of print]

PMID:
30409822
2.

MICRONEUROGRAPHIC CHARACTERIZATION OF SYMPATHETIC RESPONSES DURING 1-LEG EXERCISE IN YOUNG AND MIDDLE-AGED HUMANS.

Notarius CF, Millar PJ, Doherty CJ, Incognito AV, Haruki N, O'Donnell E, Floras JS.

Appl Physiol Nutr Metab. 2018 Jul 31. doi: 10.1139/apnm-2018-0101. [Epub ahead of print]

PMID:
30063163
3.

Sleep Apnea and Cardiovascular Disease: An Enigmatic Risk Factor.

Floras JS.

Circ Res. 2018 Jun 8;122(12):1741-1764. doi: 10.1161/CIRCRESAHA.118.310783. Review.

PMID:
29880501
4.

Heart Rate Variability Responses of Individuals With and Without Saline-Induced Obstructive Sleep Apnea.

Vena D, Bradley TD, Millar PJ, Floras JS, Rubianto J, Gavrilovic B, Perger E, Yadollahi A.

J Clin Sleep Med. 2018 Apr 15;14(4):503-510. doi: 10.5664/jcsm.7032.

5.

Exercise Blood Pressure Guidelines: Time to Re-evaluate What is Normal and Exaggerated?

Currie KD, Floras JS, La Gerche A, Goodman JM.

Sports Med. 2018 Aug;48(8):1763-1771. doi: 10.1007/s40279-018-0900-x.

PMID:
29574665
6.

Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.

Muñoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H.

J Hypertens. 2018 Jul;36(7):1477-1485. doi: 10.1097/HJH.0000000000001715.

7.

Should Maternal Hemodynamics Guide Antihypertensive Therapy in Preeclampsia?

McLaughlin K, Scholten RR, Kingdom JC, Floras JS, Parker JD.

Hypertension. 2018 Apr;71(4):550-556. doi: 10.1161/HYPERTENSIONAHA.117.10606. Epub 2018 Feb 5. Review. No abstract available.

PMID:
29437898
8.

Cortical Autonomic Network Grey Matter and Sympathetic Nerve Activity in Obstructive Sleep Apnea.

Taylor KS, Millar PJ, Murai H, Haruki N, Kimmerly DS, Bradley TD, Floras JS.

Sleep. 2017 Dec 23. doi: 10.1093/sleep/zsx208. [Epub ahead of print]

PMID:
29309669
9.

Distinct Patterns of Hyperpnea During Cheyne-Stokes Respiration: Implication for Cardiac Function in Patients With Heart Failure.

Perger E, Inami T, Lyons OD, Alshaer H, Smith S, Floras JS, Logan AG, Arzt M, Duran Cantolla J, Delgado D, Fitzpatrick M, Fleetham J, Kasai T, Kimoff RJ, Leung RST, Lorenzi Filho G, Mayer P, Mielniczuk L, Morrison DL, Parati G, Parthasarathy S, Redolfi S, Ryan CM, Series F, Tomlinson GA, Woo A, Bradley TD; ADVENT-HF Investigators.

J Clin Sleep Med. 2017 Nov 15;13(11):1235-1241. doi: 10.5664/jcsm.6788.

10.

Ambulatory Apnea Monitoring in Heart Failure: Proceed With Caution.

Floras JS.

J Am Coll Cardiol. 2017 Sep 12;70(11):1365-1367. doi: 10.1016/j.jacc.2017.07.761. No abstract available.

11.

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC.

Nat Commun. 2017 Aug 2;8:16140. doi: 10.1038/ncomms16140.

12.

Acute effects of angiotensin-converting enzyme inhibition versus angiotensin II receptor blockade on cardiac sympathetic activity in patients with heart failure.

Azevedo ER, Mak S, Floras JS, Parker JD.

Am J Physiol Regul Integr Comp Physiol. 2017 Oct 1;313(4):R410-R417. doi: 10.1152/ajpregu.00095.2017. Epub 2017 Jul 5.

13.

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC.

Nat Commun. 2017 Jun 14;8:15805. doi: 10.1038/ncomms15805. Erratum in: Nat Commun. 2017 Aug 02;8:16140.

14.

Sleep-Disordered Breathing in Heart Failure - A Therapeutic Dilemma.

Haruki N, Floras JS.

Circ J. 2017 Jun 23;81(7):903-912. doi: 10.1253/circj.CJ-17-0440. Epub 2017 May 23. Review.

15.

Design of the effect of adaptive servo-ventilation on survival and cardiovascular hospital admissions in patients with heart failure and sleep apnoea: the ADVENT-HF trial.

Lyons OD, Floras JS, Logan AG, Beanlands R, Cantolla JD, Fitzpatrick M, Fleetham J, John Kimoff R, Leung RS, Lorenzi Filho G, Mayer P, Mielniczuk L, Morrison DL, Ryan CM, Series F, Tomlinson GA, Woo A, Arzt M, Parthasarathy S, Redolfi S, Kasai T, Parati G, Delgado DH, Bradley TD; ADVENT-HF Investigators.

Eur J Heart Fail. 2017 Apr;19(4):579-587. doi: 10.1002/ejhf.790.

16.

Complexity of Sympathetic Nerve Traffic in Human Heart Failure: Seeking Inspiration.

Floras JS, Zamel N.

J Card Fail. 2017 Feb;23(2):104-106. doi: 10.1016/j.cardfail.2016.11.007. Epub 2016 Nov 28. No abstract available.

PMID:
27908780
17.

Arousal From Sleep and Sympathetic Excitation During Wakefulness.

Taylor KS, Murai H, Millar PJ, Haruki N, Kimmerly DS, Morris BL, Tomlinson G, Bradley TD, Floras JS.

Hypertension. 2016 Dec;68(6):1467-1474. Epub 2016 Oct 3.

PMID:
27698070
18.

Sleep Apnea and Left Atrial Phasic Function in Heart Failure With Reduced Ejection Fraction.

Haruki N, Tsang W, Thavendiranathan P, Woo A, Tomlinson G, Logan AG, Bradley TD, Floras JS; ADVENT-HF Investigators.

Can J Cardiol. 2016 Dec;32(12):1402-1410. doi: 10.1016/j.cjca.2016.02.047. Epub 2016 Feb 13.

PMID:
27177838
19.

Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure.

Bradley TD, Floras JS.

N Engl J Med. 2016 Feb 18;374(7):689. doi: 10.1056/NEJMc1515007. No abstract available.

PMID:
26886533
20.

Adaptive Servo Ventilation for Central Sleep Apnea: More Data, Please.

Floras JS, Logan AG, Bradley TD.

Can J Cardiol. 2016 Mar;32(3):396.e3. doi: 10.1016/j.cjca.2015.10.004. Epub 2015 Oct 22. No abstract available.

PMID:
26827240
21.

Sympathetic Nervous System in Patients with Sleep Related Breathing Disorders.

Floras JS.

Curr Hypertens Rev. 2016;12(1):18-26. Review.

PMID:
26778202
22.

After-exercise heart rate variability is attenuated in postmenopausal women and unaffected by estrogen therapy.

Harvey PJ, O'Donnell E, Picton P, Morris BL, Notarius CF, Floras JS.

Menopause. 2016 Apr;23(4):390-5. doi: 10.1097/GME.0000000000000568.

PMID:
26694735
23.

Adaptive Servo-ventilation and the Treatment of Central Sleep Apnea in Heart Failure. Let's Not Throw the Baby Out with the Bathwater.

Bradley TD, Floras JS.

Am J Respir Crit Care Med. 2016 Feb 15;193(4):357-9. doi: 10.1164/rccm.201511-2198ED. No abstract available.

PMID:
26646208
24.

Hemodynamic and neurochemical determinates of renal function in chronic heart failure.

Gilbert C, Cherney DZ, Parker AB, Mak S, Floras JS, Al-Hesayen A, Parker JD.

Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15;310(2):R167-75. doi: 10.1152/ajpregu.00190.2015. Epub 2015 Nov 11.

25.

Association between resting-state brain functional connectivity and muscle sympathetic burst incidence.

Taylor KS, Kucyi A, Millar PJ, Murai H, Kimmerly DS, Morris BL, Bradley TD, Floras JS.

J Neurophysiol. 2016 Feb 1;115(2):662-73. doi: 10.1152/jn.00675.2015. Epub 2015 Nov 4.

26.

To Pulse or Not to Pulse, Is That the Question?

Floras JS, Rao V, Billia F.

Circulation. 2015 Dec 15;132(24):2293-6. doi: 10.1161/CIRCULATIONAHA.115.019461. Epub 2015 Oct 28. No abstract available.

PMID:
26510697
27.

Muscle sympathetic activity in resting and exercising humans with and without heart failure.

Notarius CF, Millar PJ, Floras JS.

Appl Physiol Nutr Metab. 2015 Nov;40(11):1107-15. doi: 10.1139/apnm-2015-0289. Epub 2015 Aug 14. Review.

PMID:
26481289
28.

The SERVE-HF Trial.

Bradley TD, Floras JS; ADVENT-HF Investigators.

Can Respir J. 2015 Nov-Dec;22(6):313. Epub 2015 Oct 16. No abstract available.

29.

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea.

O'Donnell E, Goodman JM, Morris BL, Floras JS, Harvey PJ.

Clin Sci (Lond). 2015 Nov;129(10):885-93. doi: 10.1042/CS20150209. Epub 2015 Jul 28.

PMID:
26221028
30.

Hypertension and Sleep Apnea.

Floras JS.

Can J Cardiol. 2015 Jul;31(7):889-97. doi: 10.1016/j.cjca.2015.05.003. Epub 2015 May 16. Review.

PMID:
26112299
31.

Obstructive sleep apnea syndrome, continuous positive airway pressure and treatment of hypertension.

Floras JS.

Eur J Pharmacol. 2015 Sep 15;763(Pt A):28-37. doi: 10.1016/j.ejphar.2015.06.024. Epub 2015 Jun 18. Review.

PMID:
26096557
32.

Overnight Effects of Obstructive Sleep Apnea and Its Treatment on Stroke Volume in Patients With Heart Failure.

Kasai T, Yumino D, Redolfi S, Su MC, Ruttanaumpawan P, Mak S, Newton GE, Floras JS, Bradley TD.

Can J Cardiol. 2015 Jul;31(7):832-8. doi: 10.1016/j.cjca.2015.01.001. Epub 2015 Jan 10.

PMID:
26031298
33.

The sympathetic/parasympathetic imbalance in heart failure with reduced ejection fraction.

Floras JS, Ponikowski P.

Eur Heart J. 2015 Aug 7;36(30):1974-82b. doi: 10.1093/eurheartj/ehv087. Epub 2015 May 13. Review.

34.

Sleep apnoea in acute heart failure: fluid in flux.

Floras JS, Bradley TD.

Eur Heart J. 2015 Jun 14;36(23):1428-30. doi: 10.1093/eurheartj/ehv084. Epub 2015 Mar 22. No abstract available.

PMID:
25802394
35.

Discordant orthostatic reflex renin-angiotensin and sympathoneural responses in premenopausal exercising-hypoestrogenic women.

O'Donnell E, Goodman JM, Mak S, Murai H, Morris BL, Floras JS, Harvey PJ.

Hypertension. 2015 May;65(5):1089-95. doi: 10.1161/HYPERTENSIONAHA.114.04976. Epub 2015 Mar 16.

PMID:
25776076
36.

Acute renal failure after renal denervation.

Logan AG, Diaconita V, Ing DJ, Oreopoulos GD, Floras JS, Rajan DK.

J Vasc Interv Radiol. 2015 Mar;26(3):450-1. doi: 10.1016/j.jvir.2014.11.017. No abstract available.

PMID:
25735530
37.

Paradoxical muscle sympathetic reflex activation in human heart failure.

Millar PJ, Murai H, Floras JS.

Circulation. 2015 Feb 3;131(5):459-68. doi: 10.1161/CIRCULATIONAHA.114.010765. Epub 2014 Dec 2.

PMID:
25466974
38.

Divergent muscle sympathetic responses to dynamic leg exercise in heart failure and age-matched healthy subjects.

Notarius CF, Millar PJ, Murai H, Morris BL, Marzolini S, Oh P, Floras JS.

J Physiol. 2015 Feb 1;593(3):715-22. doi: 10.1113/jphysiol.2014.281873. Epub 2014 Dec 15.

39.

Effects of short-term continuous positive airway pressure on myocardial sympathetic nerve function and energetics in patients with heart failure and obstructive sleep apnea: a randomized study.

Hall AB, Ziadi MC, Leech JA, Chen SY, Burwash IG, Renaud J, deKemp RA, Haddad H, Mielniczuk LM, Yoshinaga K, Guo A, Chen L, Walter O, Garrard L, DaSilva JN, Floras JS, Beanlands RS.

Circulation. 2014 Sep 9;130(11):892-901. doi: 10.1161/CIRCULATIONAHA.113.005893. Epub 2014 Jul 3.

PMID:
24993098
40.

Estrogen status and the renin angiotensin aldosterone system.

O'Donnell E, Floras JS, Harvey PJ.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 1;307(5):R498-500. doi: 10.1152/ajpregu.00182.2014. Epub 2014 Jun 18. Review.

41.

Coagulation factor XIIa-kinin-mediated contribution to hypertension of chronic kidney disease.

Papageorgiou PC, Chan CT, Yeo EL, Backx PH, Floras JS.

J Hypertens. 2014 Jul;32(7):1523-33; discussion 1533. doi: 10.1097/HJH.0000000000000192.

PMID:
24733030
42.

Relationship of heart rate variability to sleepiness in patients with obstructive sleep apnea with and without heart failure.

Taranto Montemurro L, Floras JS, Picton P, Kasai T, Alshaer H, Gabriel JM, Bradley TD.

J Clin Sleep Med. 2014 Mar 15;10(3):271-6. doi: 10.5664/jcsm.3526.

43.

Renal denervation for drug-resistant hypertension: suffering its original sin, seeking redemption.

Floras JS.

Can J Cardiol. 2014 May;30(5):476-8. doi: 10.1016/j.cjca.2014.02.008. Epub 2014 Feb 19. No abstract available.

PMID:
24629493
44.

Apnea-induced cortical BOLD-fMRI and peripheral sympathoneural firing response patterns of awake healthy humans.

Kimmerly DS, Morris BL, Floras JS.

PLoS One. 2013 Dec 16;8(12):e82525. doi: 10.1371/journal.pone.0082525. eCollection 2013.

45.

Statins and the autonomic nervous system.

Millar PJ, Floras JS.

Clin Sci (Lond). 2014 Mar;126(6):401-15. doi: 10.1042/CS20130332. Review.

PMID:
24274967
46.

Preventing cardiovascular events after percutaneous coronary intervention: have we been asleep at the switch?

Arzt M, Floras JS.

Can J Cardiol. 2014 Jan;30(1):8-11. doi: 10.1016/j.cjca.2013.09.005. Epub 2013 Nov 13. No abstract available.

PMID:
24238758
47.

Sleep apnea and cardiovascular risk.

Floras JS.

J Cardiol. 2014 Jan;63(1):3-8. doi: 10.1016/j.jjcc.2013.08.009. Epub 2013 Sep 29. Review.

48.

Inverse relationship between muscle sympathetic activity during exercise and peak oxygen uptake in subjects with and without heart failure.

Notarius CF, Millar PJ, Murai H, Morris BL, Floras JS.

J Am Coll Cardiol. 2014 Feb 18;63(6):605-6. doi: 10.1016/j.jacc.2013.08.693. Epub 2013 Aug 28. No abstract available.

49.

Microneurographic evidence in healthy middle-aged humans for a sympathoexcitatory reflex activated by atrial pressure.

Millar PJ, Murai H, Morris BL, Floras JS.

Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H931-8. doi: 10.1152/ajpheart.00375.2013. Epub 2013 Jul 12.

50.

Reply to letter from Zis and Zis--concerning blood pressure variability.

Floras JS.

Can J Cardiol. 2014 Feb;30(2):248.e9. doi: 10.1016/j.cjca.2013.05.008. Epub 2013 Jul 11. No abstract available.

PMID:
23850347

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