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Items: 21

1.

PTBP1 mRNA isoforms and regulation of their translation.

Arake de Tacca LM, Pulos-Holmes MC, Floor SN, Cate JHD.

RNA. 2019 Oct;25(10):1324-1336. doi: 10.1261/rna.070193.118. Epub 2019 Jul 1.

PMID:
31263002
2.

Move Over, Genomes: Here Comes Transcriptome Engineering.

Thai B, Floor SN.

CRISPR J. 2018 Apr;1:126-127. doi: 10.1089/crispr.2018.29010.stf. No abstract available.

PMID:
31021197
3.

The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.

Iwasaki S, Iwasaki W, Takahashi M, Sakamoto A, Watanabe C, Shichino Y, Floor SN, Fujiwara K, Mito M, Dodo K, Sodeoka M, Imataka H, Honma T, Fukuzawa K, Ito T, Ingolia NT.

Mol Cell. 2019 Feb 21;73(4):738-748.e9. doi: 10.1016/j.molcel.2018.11.026. Epub 2018 Dec 27.

PMID:
30595437
4.

CRISPR-Cas9 genome editing in human cells occurs via the Fanconi anemia pathway.

Richardson CD, Kazane KR, Feng SJ, Zelin E, Bray NL, Schäfer AJ, Floor SN, Corn JE.

Nat Genet. 2018 Aug;50(8):1132-1139. doi: 10.1038/s41588-018-0174-0. Epub 2018 Jul 27.

PMID:
30054595
5.

The Traffic Jam: Polyamine Prevalence Pauses Protein Production.

Venkataramanan S, Floor SN.

Mol Cell. 2018 Apr 19;70(2):191-192. doi: 10.1016/j.molcel.2018.04.005.

6.

Widespread Translational Remodeling during Human Neuronal Differentiation.

Blair JD, Hockemeyer D, Doudna JA, Bateup HS, Floor SN.

Cell Rep. 2017 Nov 14;21(7):2005-2016. doi: 10.1016/j.celrep.2017.10.095.

7.

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.

Staahl BT, Benekareddy M, Coulon-Bainier C, Banfal AA, Floor SN, Sabo JK, Urnes C, Munares GA, Ghosh A, Doudna JA.

Nat Biotechnol. 2017 May;35(5):431-434. doi: 10.1038/nbt.3806. Epub 2017 Feb 13.

8.

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.

Iwasaki S, Floor SN, Ingolia NT.

Nature. 2016 Jun 23;534(7608):558-61. doi: 10.1038/nature17978. Epub 2016 Jun 15.

9.

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.

Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, Warnatz HJ, Yaspo ML, Adams CM, Leib RD, Breese M, Marra MA, Malkin D, Lichter P, Doudna JA, Pfister SM, Taylor MD, Chang HY, Cho YJ.

Oncotarget. 2016 May 10;7(19):28169-82. doi: 10.18632/oncotarget.8612.

10.

Tunable protein synthesis by transcript isoforms in human cells.

Floor SN, Doudna JA.

Elife. 2016 Jan 6;5. pii: e10921. doi: 10.7554/eLife.10921.

11.

Analog sensitive chemical inhibition of the DEAD-box protein DDX3.

Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA.

Protein Sci. 2016 Mar;25(3):638-49. doi: 10.1002/pro.2857. Epub 2015 Dec 26.

12.

Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome.

Floor SN, Doudna JA.

Mol Cell. 2015 Dec 3;60(5):712-714. doi: 10.1016/j.molcel.2015.11.014.

13.

Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.

Floor SN, Condon KJ, Sharma D, Jankowsky E, Doudna JA.

J Biol Chem. 2016 Jan 29;291(5):2412-21. doi: 10.1074/jbc.M115.700625. Epub 2015 Nov 23.

14.

Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.

Aglietti RA, Floor SN, McClendon CL, Jacobson MP, Gross JD.

Structure. 2013 Sep 3;21(9):1571-80. doi: 10.1016/j.str.2013.06.021. Epub 2013 Aug 1.

15.

Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.

Floor SN, Borja MS, Gross JD.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2872-7. doi: 10.1073/pnas.1113620109. Epub 2012 Feb 9.

16.

A split active site couples cap recognition by Dcp2 to activation.

Floor SN, Jones BN, Hernandez GA, Gross JD.

Nat Struct Mol Biol. 2010 Sep;17(9):1096-101. doi: 10.1038/nsmb.1879. Epub 2010 Aug 15.

17.

SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction.

Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P.

Nat Struct Mol Biol. 2008 Sep;15(9):916-23.

18.

Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.

Lampe JN, Floor SN, Gross JD, Nishida CR, Jiang Y, Trnka MJ, Ortiz de Montellano PR.

J Am Chem Soc. 2008 Dec 3;130(48):16168-9. doi: 10.1021/ja8071463.

19.

Control of mRNA decapping by Dcp2: An open and shut case?

Floor SN, Jones BN, Gross JD.

RNA Biol. 2008 Oct-Dec;5(4):189-92. Epub 2008 Oct 26.

20.

mRNA decapping is promoted by an RNA-binding channel in Dcp2.

Deshmukh MV, Jones BN, Quang-Dang DU, Flinders J, Floor SN, Kim C, Jemielity J, Kalek M, Darzynkiewicz E, Gross JD.

Mol Cell. 2008 Feb 15;29(3):324-36. doi: 10.1016/j.molcel.2007.11.027.

21.

Empirical investigation of extreme single-particle behavior of nuclear quadrupole moments in highly collective A approximately 150 superdeformed bands.

Clark ST, Hackman G, Janssens RV, Clark RM, Fallon P, Floor SN, Lane GJ, Macchiavelli AO, Norris J, Sanders SJ, Svensson CE.

Phys Rev Lett. 2001 Oct 22;87(17):172503. Epub 2001 Oct 9.

PMID:
11690269

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