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Items: 1 to 50 of 155

1.

Cutaneous B-Cell Lymphoblastic Lymphoma.

Amarasekera D, Connolly D, Gochoco A, Yang S, Grosso D, Flomenberg N, Shi W, Alpdogan SO, Duffy R, Sahu J.

Am J Dermatopathol. 2018 Dec 20. doi: 10.1097/DAD.0000000000001347. [Epub ahead of print]

PMID:
30601207
2.

Final outcomes of escalated melphalan 280 mg/m2 with amifostine cytoprotection followed autologous hematopoietic stem cell transplantation for multiple myeloma: high CR and VGPR rates do not translate into improved survival.

Hari P, Reece DE, Randhawa J, Flomenberg N, Howard DS, Badros AZ, Rapoport AP, Meisenberg BR, Filicko-Ohara J, Phillips GL, Vesole DH.

Bone Marrow Transplant. 2019 Feb;54(2):293-299. doi: 10.1038/s41409-018-0261-y. Epub 2018 Jun 15.

PMID:
29907806
3.

Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition.

Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE.

Invest New Drugs. 2018 Aug;36(4):657-666. doi: 10.1007/s10637-018-0585-x. Epub 2018 Apr 2.

PMID:
29607465
4.

Relapsed Multiple Myeloma Presenting as Intracranial Plasmacytoma and Malignant Pericardial Effusion following Recent Allogeneic Stem Cell Transplantation.

Pan J, Chen J, Filicko J, Grosso D, Nagurney M, Alpdogan O, Flomenberg N.

Case Rep Oncol. 2017 Jul 4;10(2):582-587. doi: 10.1159/000478001. eCollection 2017 May-Aug.

5.

Higher rates of relapse in maternal recipients of haploidentical hematopoietic stem cell transplantation from adult offspring donors for AML and myelodysplastic syndrome.

Geethakumari PR, Leiby B, Nair R, Alpdogan SO, Carabasi M, Filicko-O'Hara J, Gaballa S, Kasner M, Klumpp T, Martinez-Outschoorn U, Palmisiano N, Wagner JL, Porcu P, Flomenberg N, Grosso D.

Bone Marrow Transplant. 2017 Oct;52(10):1465-1467. doi: 10.1038/bmt.2017.159. Epub 2017 Jul 31. No abstract available.

PMID:
28759027
6.

New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity.

Bailey CP, Budak-Alpdogan T, Sauter CT, Panis MM, Buyukgoz C, Jeng EK, Wong HC, Flomenberg N, Alpdogan O.

Oncotarget. 2017 Jul 4;8(27):44366-44378. doi: 10.18632/oncotarget.17875.

7.

Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification.

Petruk S, Mariani SA, De Dominici M, Porazzi P, Minieri V, Cai J, Iacovitti L, Flomenberg N, Calabretta B, Mazo A.

Cell Rep. 2017 Apr 11;19(2):295-306. doi: 10.1016/j.celrep.2017.03.035.

8.

Acquired uniparental disomy in chromosome 6p as a feature of relapse after T-cell replete haploidentical hematopoietic stem cell transplantation using cyclophosphamide tolerization.

Grosso D, Johnson E, Colombe B, Alpdogan O, Carabasi M, Filicko-O'Hara J, Gaballa S, Kasner M, Klumpp T, Martinez-Outschoorn U, Wagner JL, Weiss M, Wang Z, Flomenberg N.

Bone Marrow Transplant. 2017 Apr;52(4):615-619. doi: 10.1038/bmt.2016.324. Epub 2017 Jan 9. No abstract available.

PMID:
28067885
9.

Evaluating frequency and quality of pathogen-specific T cells.

Anikeeva N, Grosso D, Flomenberg N, Sykulev Y.

Nat Commun. 2016 Oct 27;7:13264. doi: 10.1038/ncomms13264.

10.

A Two-Step Haploidentical Versus a Two-Step Matched Related Allogeneic Myeloablative Peripheral Blood Stem Cell Transplantation.

Gaballa S, Palmisiano N, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Kraft WK, Leiby B, Martinez-Outschoorn U, O'Hara W, Pro B, Rudolph S, Sharma M, Wagner JL, Weiss M, Flomenberg N, Grosso D.

Biol Blood Marrow Transplant. 2016 Jan;22(1):141-8. doi: 10.1016/j.bbmt.2015.09.017. Epub 2015 Sep 28.

11.

A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease.

Grosso D, Gaballa S, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Martinez-Outschoorn U, Wagner JL, O'Hara W, Rudolph S, Chervoneva I, Colombe B, Farley PC, Flomenberg P, Pro B, Sharma M, Shi W, Weiss M, Flomenberg N.

Biol Blood Marrow Transplant. 2015 Apr;21(4):646-52. doi: 10.1016/j.bbmt.2014.12.019. Epub 2014 Dec 23.

12.

Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation.

Bruminhent J, Wang ZX, Hu C, Wagner J, Sunday R, Bobik B, Hegarty S, Keith S, Alpdogan S, Carabasi M, Filicko-O'Hara J, Flomenberg N, Kasner M, Outschoorn UM, Weiss M, Flomenberg P.

Biol Blood Marrow Transplant. 2014 Sep;20(9):1329-34. doi: 10.1016/j.bbmt.2014.04.026. Epub 2014 May 2.

13.

Recent advances in haploidentical stem cell transplantation.

Alpdogan O, Grosso D, Flomenberg N.

Discov Med. 2013 Oct;16(88):159-65. Review.

14.

Reverse Warburg effect in a patient with aggressive B-cell lymphoma: is lactic acidosis a paraneoplastic syndrome?

Martinez-Outschoorn UE, Whitaker-Menezes D, Valsecchi M, Martinez-Cantarin MP, Dulau-Florea A, Gong J, Howell A, Flomenberg N, Pestell RG, Wagner J, Arana-Yi C, Sharma M, Sotgia F, Lisanti MP.

Semin Oncol. 2013 Aug;40(4):403-18. doi: 10.1053/j.seminoncol.2013.04.016. No abstract available.

PMID:
23972703
15.

Interleukin-15 administration increases graft-versus-tumor activity in recipients of haploidentical hematopoietic SCT.

Sauter CT, Bailey CP, Panis MM, Biswas CS, Budak-Alpdogan T, Durham A, Flomenberg N, Alpdogan O.

Bone Marrow Transplant. 2013 Sep;48(9):1237-42. doi: 10.1038/bmt.2013.47. Epub 2013 Apr 29.

PMID:
23624821
16.

Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation.

Fernández-Viña MA, Klein JP, Haagenson M, Spellman SR, Anasetti C, Noreen H, Baxter-Lowe LA, Cano P, Flomenberg N, Confer DL, Horowitz MM, Oudshoorn M, Petersdorf EW, Setterholm M, Champlin R, Lee SJ, de Lima M.

Blood. 2013 May 30;121(22):4603-10. doi: 10.1182/blood-2013-02-481945. Epub 2013 Apr 17.

17.

Haploidentical hematopoietic SCT increases graft-versus-tumor effect against renal cell carcinoma.

Budak-Alpdogan T, Sauter CT, Bailey CP, Biswas CS, Panis MM, Civriz S, Flomenberg N, Alpdogan O.

Bone Marrow Transplant. 2013 Aug;48(8):1084-90. doi: 10.1038/bmt.2013.9. Epub 2013 Feb 25.

PMID:
23435516
18.

A two-step approach to allogeneic haploidentical hematopoietic stem cell transplantation.

Grosso D, Flomenberg N.

Semin Oncol. 2012 Dec;39(6):694-706. doi: 10.1053/j.seminoncol.2012.09.006. Review.

PMID:
23206846
19.

Introduction: haploidentical bone marrow transplantation.

Flomenberg N.

Semin Oncol. 2012 Dec;39(6):627-8. doi: 10.1053/j.seminoncol.2012.09.001. No abstract available.

PMID:
23206839
20.

Double haploidentical hematopoietic stem cell transplantation results in successful engraftment of bone marrow from both donors without graft-versus-host or graft-versus-graft effects.

Biswas CS, Sauter CT, Bailey CP, Rittenberg D, Luo X, Panis MM, Budak-Alpdogan T, Grosso D, Flomenberg N, Alpdogan O.

Biol Blood Marrow Transplant. 2012 Dec;18(12):1808-18. doi: 10.1016/j.bbmt.2012.09.012. Epub 2012 Oct 16.

21.

Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.

Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Philp NJ, Pestell RG, Lisanti MP.

Cell Cycle. 2012 Apr 1;11(7):1445-54. doi: 10.4161/cc.19841. Epub 2012 Apr 1.

22.

Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance.

Ko YH, Lin Z, Flomenberg N, Pestell RG, Howell A, Sotgia F, Lisanti MP, Martinez-Outschoorn UE.

Cancer Biol Ther. 2011 Dec 15;12(12):1085-97. doi: 10.4161/cbt.12.12.18671. Epub 2011 Dec 15.

23.

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.

Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F.

Cell Cycle. 2011 Dec 1;10(23):4047-64. doi: 10.4161/cc.10.23.18151. Epub 2011 Dec 1.

24.

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.

Martinez-Outschoorn UE, Goldberg A, Lin Z, Ko YH, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP.

Cancer Biol Ther. 2011 Nov 15;12(10):924-38. doi: 10.4161/cbt.12.10.17780. Epub 2011 Nov 15.

25.

A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing.

Grosso D, Carabasi M, Filicko-O'Hara J, Kasner M, Wagner JL, Colombe B, Cornett Farley P, O'Hara W, Flomenberg P, Werner-Wasik M, Brunner J, Mookerjee B, Hyslop T, Weiss M, Flomenberg N.

Blood. 2011 Oct 27;118(17):4732-9. doi: 10.1182/blood-2011-07-365338. Epub 2011 Aug 25.

26.

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors.

Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2011 Aug 1;10(15):2504-20. Epub 2011 Aug 1.

27.

Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells.

Martinez-Outschoorn UE, Lin Z, Ko YH, Goldberg AF, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2011 Aug 1;10(15):2521-8. Epub 2011 Aug 1.

28.

Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.

Martinez-Outschoorn UE, Whitaker-Menezes D, Lin Z, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F.

Cell Cycle. 2011 Jun 1;10(11):1784-93. Epub 2011 Jun 1.

29.

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.

Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, Ertel A, Flomenberg N, Witkiewicz AK, Birbe RC, Howell A, Pavlides S, Gandara R, Pestell RG, Sotgia F, Philp NJ, Lisanti MP.

Cell Cycle. 2011 Jun 1;10(11):1772-83. Epub 2011 Jun 1.

30.

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics.

Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP.

Cell Cycle. 2011 Apr 15;10(8):1271-86. doi: 10.4161/cc.10.8.15330.

31.

The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox.

Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, Caro J, Pestell RG, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Nov 1;9(21):4297-306. Epub 2010 Nov 30. Review.

32.

HLA-C antigen mismatch is associated with worse outcome in unrelated donor peripheral blood stem cell transplantation.

Woolfrey A, Klein JP, Haagenson M, Spellman S, Petersdorf E, Oudshoorn M, Gajewski J, Hale GA, Horan J, Battiwalla M, Marino SR, Setterholm M, Ringden O, Hurley C, Flomenberg N, Anasetti C, Fernandez-Vina M, Lee SJ.

Biol Blood Marrow Transplant. 2011 Jun;17(6):885-92. doi: 10.1016/j.bbmt.2010.09.012. Epub 2010 Sep 24.

33.

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism.

Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Sep 1;9(17):3485-505. doi: 10.4161/cc.9.17.12721.

34.

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.

Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, Lisanti MP, Sotgia F.

Cell Cycle. 2010 Sep 1;9(17):3515-33. Epub 2010 Sep 9.

35.

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism.

Bonuccelli G, Tsirigos A, Whitaker-Menezes D, Pavlides S, Pestell RG, Chiavarina B, Frank PG, Flomenberg N, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Sep 1;9(17):3506-14. Epub 2010 Sep 21.

36.

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.

Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, Whitaker-Menezes D, Daumer KM, Lin Z, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Knudsen ES, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Aug 15;9(16):3256-76. doi: 10.4161/cc.9.16.12553. Epub 2010 Aug 28.

37.

Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.

Migneco G, Whitaker-Menezes D, Chiavarina B, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Flomenberg N, Tsirigos A, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Jun 15;9(12):2412-22. Epub 2010 Jun 15.

PMID:
20562527
38.

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors.

Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Daumer KM, Milliman JN, Chiavarina B, Migneco G, Witkiewicz AK, Martinez-Cantarin MP, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F.

Cell Cycle. 2010 Jun 15;9(12):2423-33. Epub 2010 Jun 15.

PMID:
20562526
39.

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation.

Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Jun 1;9(11):2201-19.

PMID:
20519932
40.

The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts.

Bonuccelli G, Whitaker-Menezes D, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Witkiewicz AK, Vander Heiden MG, Migneco G, Chiavarina B, Frank PG, Capozza F, Flomenberg N, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2010 May 15;9(10):1960-71. Epub 2010 May 15.

PMID:
20495363
41.

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling".

Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP.

Aging (Albany NY). 2010 Apr;2(4):185-99.

42.

Plerixafor (Mozobil) alone to mobilize hematopoietic stem cells from multiple myeloma patients for autologous transplantation.

Flomenberg N, Comenzo RL, Badel K, Calandra G.

Biol Blood Marrow Transplant. 2010 May;16(5):695-700. doi: 10.1016/j.bbmt.2009.12.538. Epub 2010 Jan 11.

43.

c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.

Jiao X, Katiyar S, Willmarth NE, Liu M, Ma X, Flomenberg N, Lisanti MP, Pestell RG.

J Biol Chem. 2010 Mar 12;285(11):8218-26. doi: 10.1074/jbc.M110.100792. Epub 2010 Jan 6.

44.

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.

Pavlides S, Whitaker-Menezes D, Castello-Cros R, Flomenberg N, Witkiewicz AK, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Cell Cycle. 2009 Dec;8(23):3984-4001. Epub 2009 Dec 5.

PMID:
19923890
45.

Antiviral responses following L-leucyl-L-leucine methyl esther (LLME)-treated lymphocyte infusions: graft-versus-infection without graft-versus-host disease.

Filicko-O'Hara J, Grosso D, Flomenberg PR, Friedman TM, Brunner J, Drobyski W, Ferber A, Kakhniashvili I, Keever-Taylor C, Mookerjee B, Talano JA, Wagner JI, Korngold R, Flomenberg N.

Biol Blood Marrow Transplant. 2009 Dec;15(12):1609-19. doi: 10.1016/j.bbmt.2009.08.020. Epub 2009 Sep 8.

46.

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.

Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP.

Am J Pathol. 2009 May;174(5):1650-62. doi: 10.2353/ajpath.2009.080648.

47.

Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders.

Mercier I, Jasmin JF, Pavlides S, Minetti C, Flomenberg N, Pestell RG, Frank PG, Sotgia F, Lisanti MP.

Lab Invest. 2009 Jun;89(6):614-23. doi: 10.1038/labinvest.2009.23. Epub 2009 Mar 30. Review.

48.

A Phase II trial of autologous stem cell transplantation followed by mini-allogeneic stem cell transplantation for the treatment of multiple myeloma: an analysis of Eastern Cooperative Oncology Group ECOG E4A98 and E1A97.

Vesole DH, Zhang L, Flomenberg N, Greipp PR, Lazarus HM, Huff CA; ECOG Myeloma and BMT Committees.

Biol Blood Marrow Transplant. 2009 Jan;15(1):83-91. doi: 10.1016/j.bbmt.2008.10.030. Erratum in: Biol Blood Marrow Transplant. 2009 Oct;15(10):1346. Huff, Carol A [added].

49.

Adenovirus DNA polymerase is recognized by human CD8+ T cells.

Joshi A, Tang J, Kuzma M, Wagner J, Mookerjee B, Filicko J, Carabasi M, Flomenberg N, Flomenberg P.

J Gen Virol. 2009 Jan;90(Pt 1):84-94. doi: 10.1099/vir.0.002493-0.

PMID:
19088277
50.

Complete resolution of gastric amyloidosis after autologous stem cell transplantation.

Cherian D, Braun K, Flomenberg N, Palazzo J, Kastenberg D.

Endoscopy. 2008 Sep;40 Suppl 2:E167-8. doi: 10.1055/s-2007-995793. No abstract available.

PMID:
18668456

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