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Items: 35

1.

FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update.

Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, Zirin J, Perkins L, Perrimon N, Mohr SE.

Nucleic Acids Res. 2017 Jan 4;45(D1):D672-D678. doi: 10.1093/nar/gkw977. Epub 2016 Oct 23.

2.

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.

Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N.

Genetics. 2015 Nov;201(3):843-52. doi: 10.1534/genetics.115.180208. Epub 2015 Aug 28.

3.

FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents.

Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE.

G3 (Bethesda). 2013 Sep 4;3(9):1607-16. doi: 10.1534/g3.113.007021.

4.

UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents.

Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE.

Genetics. 2013 Sep;195(1):37-45. doi: 10.1534/genetics.113.151340. Epub 2013 Jun 21.

5.

Electron-affinic sensitization VII. A correlation between structures, one-electron reduction potentials, and efficiencies of nitroimidazoles as hypoxic cell radiosensitizers. 1976.

Adams GE, Flockhart IR, Smithen CE, Stratford IJ, Wardman P, Watts ME.

Radiat Res. 2012 Aug;178(2):AV183-9. No abstract available.

PMID:
22870968
6.

FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update.

Flockhart IT, Booker M, Hu Y, McElvany B, Gilly Q, Mathey-Prevot B, Perrimon N, Mohr SE.

Nucleic Acids Res. 2012 Jan;40(Database issue):D715-9. doi: 10.1093/nar/gkr953. Epub 2011 Nov 8.

7.

An integrative approach to ortholog prediction for disease-focused and other functional studies.

Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE.

BMC Bioinformatics. 2011 Aug 31;12:357. doi: 10.1186/1471-2105-12-357.

8.

False negative rates in Drosophila cell-based RNAi screens: a case study.

Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N.

BMC Genomics. 2011 Jan 20;12:50. doi: 10.1186/1471-2164-12-50.

9.

Design and implementation of high-throughput RNAi screens in cultured Drosophila cells.

Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B.

Nat Protoc. 2007;2(9):2245-64.

PMID:
17853882
10.

FlyRNAi: the Drosophila RNAi screening center database.

Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D489-94.

11.

Effects of dexpanthenol with or without Aloe vera extract on radiation-induced oral mucositis: preclinical studies.

Dörr W, Schlichting S, Bray MA, Flockhart IR, Hopewell JW.

Int J Radiat Biol. 2005 Mar;81(3):243-50.

PMID:
16019933
12.

Modulation of the cell kinetics of pig skin by the topical application of evening primrose oil or Lioxasol.

Morris GM, Hopewell JW, Harold M, Ross GA, Nadejina NM, Gusev I, Flockhart I.

Cell Prolif. 1997 Aug-Sep;30(8-9):311-23.

PMID:
9501921
13.

Assessment of an in situ rat intestine preparation with perfused vascular bed for studying the absorption and first-pass metabolism of drugs.

Castle SJ, Tucker GT, Woods HF, Underwood JC, Nicholson CM, Havler ME, Lewis CJ, Flockhart IR, Lloyd-Jones G.

J Pharmacol Methods. 1985 Dec;14(4):255-74.

PMID:
4079443
14.

Effects of idazoxan on catecholamine systems in rat brain.

Walter DS, Flockhart IR, Haynes MJ, Howlett DR, Lane AC, Burton R, Johnson J, Dettmar PW.

Biochem Pharmacol. 1984 Aug 15;33(16):2553-7.

PMID:
6147143
15.

The radioimmunoassay of buprenorphine.

Bartlett AJ, Lloyd-Jones JG, Rance MJ, Flockhart IR, Dockray GJ, Bennett MR, Moore RA.

Eur J Clin Pharmacol. 1980 Oct;18(4):339-45.

PMID:
7439255
16.

Misonidazole-a drug for trial in radiotherapy and oncology.

Dische S, Saunders MI, Flockhart IR, Lee ME, Anderson P.

Int J Radiat Oncol Biol Phys. 1979 Jun;5(6):851-60. No abstract available.

PMID:
227822
17.

Structure-activity relationships in the development of hypoxic cell radiosensitizers. I. Sensitization efficiency.

Adams GE, Clarke ED, Flockhart IR, Jacobs RS, Sehmi DS, Stratford IJ, Wardman P, Watts ME, Parrick J, Wallace RG, Smithen CE.

Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Feb;35(2):133-50.

PMID:
312783
18.

A metabolite of the 2-nitroimidazole misonidazole with radiosensitizing properties.

Flockhart IR, Sheldon PW, Stratford IJ, Watts ME.

Int J Radiat Biol Relat Stud Phys Chem Med. 1978 Jul;34(1):91-4. No abstract available.

PMID:
309446
19.

Some aspects of the metabolism of misonidazole.

Flockhart IR, Malcolm SL, Marten TR, Parkins CS, Ruane RJ, Troup D.

Br J Cancer Suppl. 1978 Jun;3:264-7.

20.

The rationale for the development of improved hypoxic cell radiosensitizers.

Wardman P, Clarke ED, Flockhart IR, Wallace RG.

Br J Cancer Suppl. 1978 Jun;3:1-5.

21.
22.

The neurotoxicity of misonidazole and its relationship to dose, half-life and concentration in the serum.

Saunders ME, Dische S, Anderson P, Flockhart IR.

Br J Cancer Suppl. 1978 Jun;3:268-70.

23.

Estimation of the hypoxic cell-sensitiser misonidazole and its O-demethylated metabolite in biological materials by reversed-phase high-performance liquid chromatography.

Workman P, Little CJ, Marten TR, Dale AD, Ruane RJ, Flockhart IR, Bleehen NM.

J Chromatogr. 1978 May 1;145(3):507-12. No abstract available.

PMID:
659541
24.

Hypoxic cell sensitization by misonidazole in vivo and in vitro.

McNally NJ, Denekamp J, Sheldon PW, Flockhart IR.

Br J Radiol. 1978 Apr;51(604):317-8. No abstract available.

PMID:
647189
25.

Radiosensitization by misonidazole (Ro 07-0582). The importance of timing and tumor concentration of sensitizer.

McNally NJ, Denekamp J, Sheldon P, Flockhart IR, Stewart FA.

Radiat Res. 1978 Mar;73(3):568-80. No abstract available.

PMID:
273269
26.

Pharmacokinetic and metabolic studies of the hypoxic cell radiosensitizer misonidazole.

Flockhart IR, Large P, Troup D, Malcolm SL, Marten TR.

Xenobiotica. 1978 Feb;8(2):97-105.

PMID:
415443
27.

Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses.

Dische S, Saunders MI, Lee ME, Adams GE, Flockhart IR.

Br J Cancer. 1977 May;35(5):567-79.

28.

Electron-affinic sensitization. VII. A correlation between structures, one-electron reduction potentials, and efficiencies of nitroimidazoles as hypoxic cell radiosensitizers.

Adams GE, Flockhart IR, Smithen CE, Stratford IJ, Wardman P, Watts ME.

Radiat Res. 1976 Jul;67(1):9-20. No abstract available.

PMID:
940937
29.

Clinical testing of the radiosensitiser Ro-07-0582. I. Dose tolerance, serum and tumour concentrations.

Gray AJ, Dische S, Adams GE, Flockhart IR, Foster JL.

Clin Radiol. 1976 Apr;27(2):151-7.

PMID:
776493
30.

Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results.

Foster JL, Flockhart IR, Dische S, Gray A, Lenox-Smith I, Smithen CE.

Br J Cancer. 1975 Jun;31(6):679-83. No abstract available.

31.
32.

The partial purification and some properties of a human erythrocyte 4-nitroacetophenone reductases.

Cohen GM, Flockhart IR.

Biochem Soc Trans. 1975;3(1):178-9. No abstract available.

PMID:
1126532
33.

Proceedings: Some pharmacological considerations important in the selection of radiosensitizing drugs.

Foster JL, Flockhart IR.

Br J Radiol. 1975 Jan;48(565):75-6. No abstract available.

PMID:
1109647
34.
35.

The fate of 4,5- and 5,6-dichloro-2-trifluoromethybenzimidazole in the rat and rabbit.

Flockhart IR, Smith RL, Williams RT.

Biochem J. 1968 Dec;110(3):32P-33P. No abstract available.

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