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Items: 41

1.

Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness.

Dragset MS, Ioerger TR, Zhang YJ, Mærk M, Ginbot Z, Sacchettini JC, Flo TH, Rubin EJ, Steigedal M.

Sci Rep. 2019 Aug 6;9(1):11394. doi: 10.1038/s41598-019-47905-y.

2.

Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels.

Thorsvik S, van Beelen Granlund A, Svendsen TD, Bakke I, Røyset ES, Flo TH, Damås JK, Østvik AE, Bruland T, Sandvik AK.

J Pathol. 2019 Jul;248(3):316-325. doi: 10.1002/path.5258. Epub 2019 Mar 19.

3.

Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium.

Kannan N, Lai YP, Haug M, Lilleness MK, Bakke SS, Marstad A, Hov H, Naustdal T, Afset JE, Ioerger TR, Flo TH, Steigedal M.

Infect Immun. 2019 Mar 25;87(4). pii: e00323-18. doi: 10.1128/IAI.00323-18. Print 2019 Apr.

4.

A Sugar Rush for Innate Immunity.

Orning P, Flo TH, Lien E.

Cell Host Microbe. 2018 Oct 10;24(4):461-463. doi: 10.1016/j.chom.2018.09.017.

PMID:
30308148
5.

Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination.

Haug M, Brede G, Håkerud M, Nedberg AG, Gederaas OA, Flo TH, Edwards VT, Selbo PK, Høgset A, Halaas Ø.

Front Immunol. 2018 Apr 4;9:650. doi: 10.3389/fimmu.2018.00650. eCollection 2018.

6.

Statistikk og annen løgn.

Flo TH.

Tidsskr Nor Laegeforen. 2018 Feb 16;138(4). doi: 10.4045/tidsskr.18.0104. Print 2018 Feb 20. Norwegian. No abstract available.

PMID:
29460569
Free Article
7.

Correction: Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages.

Gidon A, Åsberg SE, Louet C, Ryan L, Haug M, Flo TH.

PLoS Pathog. 2017 Nov 7;13(11):e1006712. doi: 10.1371/journal.ppat.1006712. eCollection 2017 Nov.

8.

Author Correction: Molecular basis of mycobacterial survival in macrophages.

Awuh JA, Flo TH.

Cell Mol Life Sci. 2018 Jan;75(1):161. doi: 10.1007/s00018-017-2683-x.

PMID:
29022045
9.

N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.

Mildenberger J, Johansson I, Sergin I, Kjøbli E, Damås JK, Razani B, Flo TH, Bjørkøy G.

Autophagy. 2017 Oct 3;13(10):1664-1678. doi: 10.1080/15548627.2017.1345411. Epub 2017 Aug 18.

10.

Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages.

Gidon A, Åsberg SE, Louet C, Ryan L, Haug M, Flo TH.

PLoS Pathog. 2017 Aug 14;13(8):e1006551. doi: 10.1371/journal.ppat.1006551. eCollection 2017 Aug. Erratum in: PLoS Pathog. 2017 Nov 7;13(11):e1006712.

11.

Molecular basis of mycobacterial survival in macrophages.

Awuh JA, Flo TH.

Cell Mol Life Sci. 2017 May;74(9):1625-1648. doi: 10.1007/s00018-016-2422-8. Epub 2016 Nov 19. Review. Erratum in: Cell Mol Life Sci. 2018 Jan;75(1):161.

PMID:
27866220
12.

Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease.

Thorsvik S, Damås JK, Granlund AV, Flo TH, Bergh K, Østvik AE, Sandvik AK.

J Gastroenterol Hepatol. 2017 Jan;32(1):128-135. doi: 10.1111/jgh.13598.

PMID:
27640344
13.

Low levels of short- and medium-chain acylcarnitines in HIV-infected patients.

Waagsbø B, Svardal A, Ueland T, Landrø L, Øktedalen O, Berge RK, Flo TH, Aukrust P, Damås JK.

Eur J Clin Invest. 2016 May;46(5):408-17. doi: 10.1111/eci.12609. Epub 2016 Mar 7.

PMID:
26913383
14.

Seeing a Mycobacterium-Infected Cell in Nanoscale 3D: Correlative Imaging by Light Microscopy and FIB/SEM Tomography.

Beckwith MS, Beckwith KS, Sikorski P, Skogaker NT, Flo TH, Halaas Ø.

PLoS One. 2015 Sep 25;10(9):e0134644. doi: 10.1371/journal.pone.0134644. eCollection 2015.

15.

Benzoic Acid-Inducible Gene Expression in Mycobacteria.

Dragset MS, Barczak AK, Kannan N, Mærk M, Flo TH, Valla S, Rubin EJ, Steigedal M.

PLoS One. 2015 Sep 8;10(9):e0134544. doi: 10.1371/journal.pone.0134544. eCollection 2015.

16.

Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages.

Awuh JA, Haug M, Mildenberger J, Marstad A, Do CP, Louet C, Stenvik J, Steigedal M, Damås JK, Halaas Ø, Flo TH.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4272-80. doi: 10.1073/pnas.1423449112. Epub 2015 Jul 20.

17.

TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway.

Bergstrøm B, Aune MH, Awuh JA, Kojen JF, Blix KJ, Ryan L, Flo TH, Mollnes TE, Espevik T, Stenvik J.

J Immunol. 2015 Aug 1;195(3):1100-11. doi: 10.4049/jimmunol.1403176. Epub 2015 Jun 17.

18.

Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection.

Steigedal M, Marstad A, Haug M, Damås JK, Strong RK, Roberts PL, Himpsl SD, Stapleton A, Hooton TM, Mobley HL, Hawn TR, Flo TH.

J Immunol. 2014 Dec 15;193(12):6081-9. doi: 10.4049/jimmunol.1401528. Epub 2014 Nov 14.

19.

Dynamics of immune effector mechanisms during infection with Mycobacterium avium in C57BL/6 mice.

Haug M, Awuh JA, Steigedal M, Frengen Kojen J, Marstad A, Nordrum IS, Halaas Ø, Flo TH.

Immunology. 2013 Oct;140(2):232-43. doi: 10.1111/imm.12131.

20.

Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2.

Østvik AE, Granlund AV, Torp SH, Flatberg A, Beisvåg V, Waldum HL, Flo TH, Espevik T, Damås JK, Sandvik AK.

Clin Exp Immunol. 2013 Sep;173(3):502-11. doi: 10.1111/cei.12136.

21.

Counting mycobacteria in infected human cells and mouse tissue: a comparison between qPCR and CFU.

Pathak S, Awuh JA, Leversen NA, Flo TH, Asjø B.

PLoS One. 2012;7(4):e34931. doi: 10.1371/journal.pone.0034931. Epub 2012 Apr 19.

22.

Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS).

Damås JK, Øktedalen O, Ueland T, Landrø L, Barstad J, Müller F, Frøland SS, Flo TH, Aukrust P.

Clin Exp Immunol. 2012 Mar;167(3):492-8. doi: 10.1111/j.1365-2249.2011.04524.x.

23.

Serum levels of neutrophil gelatinase-associated lipocalin are associated with microalbuminuria in HIV-infected patients.

Damås JK, Bækken M, Ueland T, Manner IW, Os I, Yndestad A, Flo TH, Øktedalen O, Aukrust P.

J Acquir Immune Defic Syndr. 2012 Feb 1;59(2):e24-5. doi: 10.1097/QAI.0b013e31823f35a7. No abstract available.

PMID:
22245717
24.

The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA*.

Nymo SH, Ueland T, Askevold ET, Flo TH, Kjekshus J, Hulthe J, Wikstrand J, McMurray J, Van Veldhuisen DJ, Gullestad L, Aukrust P, Yndestad A.

J Intern Med. 2012 May;271(5):436-43. doi: 10.1111/j.1365-2796.2011.02503.x. Epub 2012 Jan 16.

25.

Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers.

Pukstad BS, Ryan L, Flo TH, Stenvik J, Moseley R, Harding K, Thomas DW, Espevik T.

J Dermatol Sci. 2010 Aug;59(2):115-22. doi: 10.1016/j.jdermsci.2010.05.003. Epub 2010 May 27.

PMID:
20558044
26.

Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway.

Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH.

J Infect Dis. 2010 Mar;201(5):783-92. doi: 10.1086/650493.

27.

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.

Yndestad A, Landrø L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Frøland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Øie E, Gullestad L, Aukrust P.

Eur Heart J. 2009 May;30(10):1229-36. doi: 10.1093/eurheartj/ehp088. Epub 2009 Mar 26.

PMID:
19329498
28.

Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever.

Damås JK, Davì G, Jensenius M, Santilli F, Otterdal K, Ueland T, Flo TH, Lien E, Espevik T, Frøland SS, Vitale G, Raoult D, Aukrust P.

J Infect. 2009 Jan;58(1):68-75. doi: 10.1016/j.jinf.2008.11.008. Epub 2008 Dec 16.

PMID:
19091423
29.

Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy.

Landrø L, Damås JK, Flo TH, Heggelund L, Ueland T, Tjønnfjord GE, Espevik T, Aukrust P, Frøland SS.

Clin Exp Immunol. 2008 Apr;152(1):57-63. doi: 10.1111/j.1365-2249.2008.03592.x. Epub 2008 Jan 28.

30.

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron.

Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A.

Nature. 2004 Dec 16;432(7019):917-21. Epub 2004 Nov 7.

31.

Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target.

Schjetne KW, Thompson KM, Nilsen N, Flo TH, Fleckenstein B, Iversen JG, Espevik T, Bogen B.

J Immunol. 2003 Jul 1;171(1):32-6.

32.

Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.

Flo TH, Ryan L, Latz E, Takeuchi O, Monks BG, Lien E, Halaas Ø, Akira S, Skjåk-Braek G, Golenbock DT, Espevik T.

J Biol Chem. 2002 Sep 20;277(38):35489-95. Epub 2002 Jun 27.

33.

Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.

Dybdahl B, Wahba A, Lien E, Flo TH, Waage A, Qureshi N, Sellevold OF, Espevik T, Sundan A.

Circulation. 2002 Feb 12;105(6):685-90.

PMID:
11839622
34.

Differential expression of Toll-like receptor 2 in human cells.

Flo TH, Halaas O, Torp S, Ryan L, Lien E, Dybdahl B, Sundan A, Espevik T.

J Leukoc Biol. 2001 Mar;69(3):474-81.

PMID:
11261796
35.

Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.

Wang JE, Warris A, Ellingsen EA, Jørgensen PF, Flo TH, Espevik T, Solberg R, Verweij PE, Aasen AO.

Infect Immun. 2001 Apr;69(4):2402-6.

36.

Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.

Flo TH, Ryan L, Kilaas L, Skjâk-Braek G, Ingalls RR, Sundan A, Golenbock DT, Espevik T.

Infect Immun. 2000 Dec;68(12):6770-6.

37.

Beta 2 integrins are involved in cytokine responses to whole Gram-positive bacteria.

Cuzzola M, Mancuso G, Beninati C, Biondo C, Genovese F, Tomasello F, Flo TH, Espevik T, Teti G.

J Immunol. 2000 Jun 1;164(11):5871-6.

38.

Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.

Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T.

J Immunol. 2000 Feb 15;164(4):2064-9.

39.

Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products.

Cuzzola M, Mancuso G, Beninati C, Biondo C, von Hunolstein C, Orefici G, Espevik T, Flo TH, Teti G.

Infect Immun. 2000 Feb;68(2):994-8.

40.

Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

Lien E, Sellati TJ, Yoshimura A, Flo TH, Rawadi G, Finberg RW, Carroll JD, Espevik T, Ingalls RR, Radolf JD, Golenbock DT.

J Biol Chem. 1999 Nov 19;274(47):33419-25.

41.

The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles.

Berntzen G, Flo TH, Medvedev A, Kilaas L, Skjåk-Braek G, Sundan A, Espevik T.

Clin Diagn Lab Immunol. 1998 May;5(3):355-61.

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