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Items: 1 to 50 of 81

1.

Salmonellosis outbreak with novel Salmonella enterica subspecies enterica serotype (11:z41:e,n,z15) attributable to sesame products in five European countries, 2016 to 2017.

Meinen A, Simon S, Banerji S, Szabo I, Malorny B, Borowiak M, Hadziabdic S, Becker N, Luber P, Lohr D, Harms C, Plenge-Bönig A, Mellou K, Mandilara G, Mossong J, Ragimbeau C, Weicherding P, Hau P, Dědičová D, Šafaříková L, Nair S, Dallman TJ, Larkin L, McCormick J, De Pinna E, Severi E, Kotila S, Niskanen T, Rizzi V, Deserio D, Flieger A, Stark K.

Euro Surveill. 2019 Sep;24(36). doi: 10.2807/1560-7917.ES.2019.24.36.1800543.

2.

Whole-Genome-Based Public Health Surveillance of Less Common Shiga Toxin-Producing Escherichia coli Serovars and Untypeable Strains Identifies Four Novel O Genotypes.

Lang C, Hiller M, Konrad R, Fruth A, Flieger A.

J Clin Microbiol. 2019 Sep 24;57(10). pii: e00768-19. doi: 10.1128/JCM.00768-19. Print 2019 Oct.

3.

Fluoroquinolone-Resistant Salmonella enterica, Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana.

Dekker D, Eibach D, Boahen KG, Akenten CW, Pfeifer Y, Zautner AE, Mertens E, Krumkamp R, Jaeger A, Flieger A, Owusu-Dabo E, May J.

Foodborne Pathog Dis. 2019 May;16(5):352-358. doi: 10.1089/fpd.2018.2562. Epub 2019 Mar 23.

4.

A Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis.

Halbedel S, Prager R, Banerji S, Kleta S, Trost E, Nishanth G, Alles G, Hölzel C, Schlesiger F, Pietzka A, Schlüter D, Flieger A.

Emerg Microbes Infect. 2019;8(1):17-28. doi: 10.1080/22221751.2018.1558960.

5.

Pathways of host cell exit by intracellular pathogens.

Flieger A, Frischknecht F, Häcker G, Hornef MW, Pradel G.

Microb Cell. 2018 Oct 18;5(12):525-544. doi: 10.15698/mic2018.12.659. Review.

6.

Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence.

Lang C, Fruth A, Holland G, Laue M, Mühlen S, Dersch P, Flieger A.

Emerg Microbes Infect. 2018 Dec 5;7(1):203. doi: 10.1038/s41426-018-0209-8.

7.

Shiga toxin-producing Escherichia coli O103:H2 outbreak in Germany after school trip to Austria due to raw cow milk, 2017 - The important role of international collaboration for outbreak investigations.

Mylius M, Dreesman J, Pulz M, Pallasch G, Beyrer K, Claußen K, Allerberger F, Fruth A, Lang C, Prager R, Flieger A, Schlager S, Kalhöfer D, Mertens E.

Int J Med Microbiol. 2018 Jul;308(5):539-544. doi: 10.1016/j.ijmm.2018.05.005. Epub 2018 May 29.

PMID:
29884330
8.

Whole-Genome Sequencing of Recent Listeria monocytogenes Isolates from Germany Reveals Population Structure and Disease Clusters.

Halbedel S, Prager R, Fuchs S, Trost E, Werner G, Flieger A.

J Clin Microbiol. 2018 May 25;56(6). pii: e00119-18. doi: 10.1128/JCM.00119-18. Print 2018 Jun.

9.

Evaluation of WGS based approaches for investigating a food-borne outbreak caused by Salmonella enterica serovar Derby in Germany.

Simon S, Trost E, Bender J, Fuchs S, Malorny B, Rabsch W, Prager R, Tietze E, Flieger A.

Food Microbiol. 2018 May;71:46-54. doi: 10.1016/j.fm.2017.08.017. Epub 2017 Aug 25.

PMID:
29366468
10.

Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity.

Lang C, Hiller M, Flieger A.

Sci Rep. 2017 Nov 24;7(1):16313. doi: 10.1038/s41598-017-12796-4.

11.

glnA Truncation in Salmonella enterica Results in a Small Colony Variant Phenotype, Attenuated Host Cell Entry, and Reduced Expression of Flagellin and SPI-1-Associated Effector Genes.

Aurass P, Düvel J, Karste S, Nübel U, Rabsch W, Flieger A.

Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e01838-17. doi: 10.1128/AEM.01838-17. Print 2018 Jan 15.

12.

Secreted phospholipases of the lung pathogen Legionella pneumophila.

Hiller M, Lang C, Michel W, Flieger A.

Int J Med Microbiol. 2018 Jan;308(1):168-175. doi: 10.1016/j.ijmm.2017.10.002. Epub 2017 Oct 28. Review.

PMID:
29108710
13.

Phospholipases during membrane dynamics in malaria parasites.

Flammersfeld A, Lang C, Flieger A, Pradel G.

Int J Med Microbiol. 2018 Jan;308(1):129-141. doi: 10.1016/j.ijmm.2017.09.015. Epub 2017 Sep 23. Review.

14.

Molecular Tracing to Find Source of Protracted Invasive Listeriosis Outbreak, Southern Germany, 2012-2016.

Kleta S, Hammerl JA, Dieckmann R, Malorny B, Borowiak M, Halbedel S, Prager R, Trost E, Flieger A, Wilking H, Vygen-Bonnet S, Busch U, Messelhäußer U, Horlacher S, Schönberger K, Lohr D, Aichinger E, Luber P, Hensel A, Al Dahouk S.

Emerg Infect Dis. 2017 Oct;23(10):1680-1683. doi: 10.3201/eid2310.161623.

15.

Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017.

Vygen-Bonnet S, Rosner B, Wilking H, Fruth A, Prager R, Kossow A, Lang C, Simon S, Seidel J, Faber M, Schielke A, Michaelis K, Holzer A, Kamphausen R, Kalhöfer D, Thole S, Mellmann A, Flieger A, Stark K.

Euro Surveill. 2017 May 25;22(21). pii: 30541. doi: 10.2807/1560-7917.ES.2017.22.21.30541.

16.

Genome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm.

Aurass P, Karste S, Trost E, Glaeser SP, Kämpfer P, Flieger A.

Genome Announc. 2017 Jun 8;5(23). pii: e00487-17. doi: 10.1128/genomeA.00487-17.

17.

Paracoccus contaminans sp. nov., isolated from a contaminated water microcosm.

Kämpfer P, Aurass P, Karste S, Flieger A, Glaeser SP.

Int J Syst Evol Microbiol. 2016 Dec;66(12):5101-5105. doi: 10.1099/ijsem.0.001478. Epub 2016 Sep 5.

PMID:
27599853
18.

Bony injuries in homicide cases (1994-2014). A retrospective study.

Flieger A, Kölzer SC, Plenzig S, Heinbuch S, Kettner M, Ramsthaler F, Verhoff MA.

Int J Legal Med. 2016 Sep;130(5):1401-8. doi: 10.1007/s00414-016-1407-3. Epub 2016 Jul 11.

PMID:
27401087
19.

Bacterial Sphingomyelinases and Phospholipases as Virulence Factors.

Flores-Díaz M, Monturiol-Gross L, Naylor C, Alape-Girón A, Flieger A.

Microbiol Mol Biol Rev. 2016 Jun 15;80(3):597-628. doi: 10.1128/MMBR.00082-15. Print 2016 Sep. Review.

20.

Life Stage-specific Proteomes of Legionella pneumophila Reveal a Highly Differential Abundance of Virulence-associated Dot/Icm effectors.

Aurass P, Gerlach T, Becher D, Voigt B, Karste S, Bernhardt J, Riedel K, Hecker M, Flieger A.

Mol Cell Proteomics. 2016 Jan;15(1):177-200. doi: 10.1074/mcp.M115.053579. Epub 2015 Nov 6.

21.

Molecular epidemiological view on Shiga toxin-producing Escherichia coli causing human disease in Germany: Diversity, prevalence, and outbreaks.

Fruth A, Prager R, Tietze E, Rabsch W, Flieger A.

Int J Med Microbiol. 2015 Oct;305(7):697-704. doi: 10.1016/j.ijmm.2015.08.020. Epub 2015 Aug 21. Review.

PMID:
26372529
22.

A transferable plasticity region in Campylobacter coli allows isolates of an otherwise non-glycolytic food-borne pathogen to catabolize glucose.

Vorwerk H, Huber C, Mohr J, Bunk B, Bhuju S, Wensel O, Spröer C, Fruth A, Flieger A, Schmidt-Hohagen K, Schomburg D, Eisenreich W, Hofreuter D.

Mol Microbiol. 2015 Dec;98(5):809-30. doi: 10.1111/mmi.13159. Epub 2015 Sep 10.

23.

Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor.

Schroeder GN, Aurass P, Oates CV, Tate EW, Hartland EL, Flieger A, Frankel G.

Infect Immun. 2015 Oct;83(10):3989-4002. doi: 10.1128/IAI.00785-15. Epub 2015 Jul 27.

24.

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI.

Sci Rep. 2015 Jun 1;5:10734. doi: 10.1038/srep10734.

25.

Comparative genomic analysis of two novel sporadic Shiga toxin-producing Escherichia coli O104:H4 strains isolated 2011 in Germany.

Tietze E, Dabrowski PW, Prager R, Radonic A, Fruth A, Auraß P, Nitsche A, Mielke M, Flieger A.

PLoS One. 2015 Apr 2;10(4):e0122074. doi: 10.1371/journal.pone.0122074. eCollection 2015.

26.

A systematic proteomic analysis of Listeria monocytogenes house-keeping protein secretion systems.

Halbedel S, Reiss S, Hahn B, Albrecht D, Mannala GK, Chakraborty T, Hain T, Engelmann S, Flieger A.

Mol Cell Proteomics. 2014 Nov;13(11):3063-81. doi: 10.1074/mcp.M114.041327. Epub 2014 Jul 23.

27.

Oligomerization inhibits Legionella pneumophila PlaB phospholipase A activity.

Kuhle K, Krausze J, Curth U, Rössle M, Heuner K, Lang C, Flieger A.

J Biol Chem. 2014 Jul 4;289(27):18657-66. doi: 10.1074/jbc.M114.573196. Epub 2014 May 8. Erratum in: J Biol Chem. 2014 Jul 4;289(27):18667.

28.

Two novel EHEC/EAEC hybrid strains isolated from human infections.

Prager R, Lang C, Aurass P, Fruth A, Tietze E, Flieger A.

PLoS One. 2014 Apr 21;9(4):e95379. doi: 10.1371/journal.pone.0095379. eCollection 2014.

29.

Rabbit monoclonal antibodies directed at the T3SS effector protein YopM identify human pathogenic Yersinia isolates.

Rüter C, Silva MR, Grabowski B, Lubos ML, Scharnert J, Poceva M, von Tils D, Flieger A, Heesemann J, Bliska JB, Schmidt MA.

Int J Med Microbiol. 2014 May;304(3-4):444-51. doi: 10.1016/j.ijmm.2014.02.003. Epub 2014 Feb 18.

PMID:
24636859
30.

Legionella phospholipases implicated in virulence.

Kuhle K, Flieger A.

Curr Top Microbiol Immunol. 2013;376:175-209. doi: 10.1007/82_2013_348. Review.

PMID:
23925490
31.

Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany.

Grad YH, Lipsitch M, Griggs AD, Haas BJ, Shea TP, McCowan C, Montmayeur A, FitzGerald M, Wortman JR, Krogfelt KA, Bingen E, Weill FX, Tietze E, Flieger A, Lander ES, Nusbaum C, Birren BW, Hung DT, Hanage WP.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3629-30. No abstract available.

32.

The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi.

Aurass P, Schlegel M, Metwally O, Harding CR, Schroeder GN, Frankel G, Flieger A.

J Biol Chem. 2013 Apr 19;288(16):11080-92. doi: 10.1074/jbc.M112.426049. Epub 2013 Mar 1.

33.

Comparing the presence of different genes in Salmonella subspecies I-IV and development of a diagnostic multiplex PCR method for identification of Salmonella subspecies.

Münch S, Wernery U, Kinne J, Joseph M, Braun P, Pees M, Flieger A, Fruth A, Rabsch W.

Berl Munch Tierarztl Wochenschr. 2013 Jan-Feb;126(1-2):16-24.

PMID:
23367664
34.

[Role of pathogen surveillance and subtyping in outbreak recognition of food-borne bacterial infections. Microbiological perspective - Aims, methods and prospects of pathogen subtyping].

Flieger A, Mielke M, Tietze E.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Jan;56(1):42-6. doi: 10.1007/s00103-012-1592-2. German.

PMID:
23275955
35.

Carrier prevalence, secondary household transmission, and long-term shedding in 2 districts during the Escherichia coli O104:H4 outbreak in Germany, 2011.

Sin MA, Takla A, Flieger A, Prager R, Fruth A, Tietze E, Fink E, Korte J, Schink S, Höhle M, Eckmanns T.

J Infect Dis. 2013 Feb 1;207(3):432-8. doi: 10.1093/infdis/jis702. Epub 2012 Nov 21.

PMID:
23175763
36.

Legionella phospholipases implicated in infection: determination of enzymatic activities.

Seipel K, Flieger A.

Methods Mol Biol. 2013;954:355-65. doi: 10.1007/978-1-62703-161-5_22.

PMID:
23150408
37.

Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase.

Lang C, Rastew E, Hermes B, Siegbrecht E, Ahrends R, Banerji S, Flieger A.

J Biol Chem. 2012 Jul 6;287(28):23464-78. doi: 10.1074/jbc.M112.346387. Epub 2012 May 11.

38.

Prevalence, serovars, phage types, and antibiotic susceptibilities of Salmonella strains isolated from animals in the United Arab Emirates from 1996 to 2009.

Münch S, Braun P, Wernery U, Kinne J, Pees M, Flieger A, Tietze E, Rabsch W.

Trop Anim Health Prod. 2012 Oct;44(7):1725-38. doi: 10.1007/s11250-012-0130-4. Epub 2012 Apr 4.

PMID:
22476789
39.

DivIVA affects secretion of virulence-related autolysins in Listeria monocytogenes.

Halbedel S, Hahn B, Daniel RA, Flieger A.

Mol Microbiol. 2012 Feb;83(4):821-39. doi: 10.1111/j.1365-2958.2012.07969.x. Epub 2012 Jan 18.

40.

Outbreaks of virulent diarrheagenic Escherichia coli--are we in control?

Werber D, Krause G, Frank C, Fruth A, Flieger A, Mielke M, Schaade L, Stark K.

BMC Med. 2012 Feb 2;10:11. doi: 10.1186/1741-7015-10-11. Review.

41.
42.

Characterisation of Legionella pneumophila phospholipases and their impact on host cells.

Lang C, Flieger A.

Eur J Cell Biol. 2011 Nov;90(11):903-12. doi: 10.1016/j.ejcb.2010.12.003. Epub 2011 Feb 20. Review.

PMID:
21342713
43.

Legionella pneumophila-induced IκBζ-dependent expression of interleukin-6 in lung epithelium.

Lorenz J, Zahlten J, Pollok I, Lippmann J, Scharf S, N'Guessan PD, Opitz B, Flieger A, Suttorp N, Hippenstiel S, Schmeck B.

Eur Respir J. 2011 Mar;37(3):648-57. doi: 10.1183/09031936.00200009. Epub 2010 Jul 22.

44.

Legionella pneumophila induces human beta defensin-3 in pulmonary cells.

Scharf S, Vardarova K, Lang F, Schmeck B, Opitz B, Flieger A, Heuner K, Hippenstiel S, Suttorp N, N'Guessan PD.

Respir Res. 2010 Jul 8;11:93. doi: 10.1186/1465-9921-11-93.

45.

Update: Multinational listeriosis outbreak due to 'Quargel', a sour milk curd cheese, caused by two different L. monocytogenes serotype 1/2a strains, 2009-2010.

Fretz R, Pichler J, Sagel U, Much P, Ruppitsch W, Pietzka AT, Stöger A, Huhulescu S, Heuberger S, Appl G, Werber D, Stark K, Prager R, Flieger A, Karpísková R, Pfaff G, Allerberger F.

Euro Surveill. 2010 Apr 22;15(16). pii: 19543.

46.

Characterisation of multidrug-resistant Salmonella Typhimurium 4,[5],12:i:- DT193 strains carrying a novel genomic island adjacent to the thrW tRNA locus.

Trüpschuch S, Laverde Gomez JA, Ediberidze Ia, Flieger A, Rabsch W.

Int J Med Microbiol. 2010 Jun;300(5):279-88. doi: 10.1016/j.ijmm.2010.02.001. Epub 2010 Mar 19.

PMID:
20303825
47.

Induction of human β-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-κB, and AP-1.

Scharf S, Hippenstiel S, Flieger A, Suttorp N, N'Guessan PD.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L687-95. doi: 10.1152/ajplung.00365.2009. Epub 2010 Feb 12.

48.

Phospholipase PlaB is a new virulence factor of Legionella pneumophila.

Schunder E, Adam P, Higa F, Remer KA, Lorenz U, Bender J, Schulz T, Flieger A, Steinert M, Heuner K.

Int J Med Microbiol. 2010 Jun;300(5):313-23. doi: 10.1016/j.ijmm.2010.01.002. Epub 2010 Feb 12.

PMID:
20153694
49.

Listeriosis outbreak caused by acid curd cheese Quargel , Austria and Germany 2009.

Fretz R, Sagel U, Ruppitsch W, Pietzka A, Stoger A, Huhulescu S, Heuberger S, Pichler J, Much P, Pfaff G, Stark K, Prager R, Flieger A, Feenstra O, Allerberger F.

Euro Surveill. 2010 Feb 4;15(5). pii: 19477.

50.

Phospholipase PlaB of Legionella pneumophila represents a novel lipase family: protein residues essential for lipolytic activity, substrate specificity, and hemolysis.

Bender J, Rydzewski K, Broich M, Schunder E, Heuner K, Flieger A.

J Biol Chem. 2009 Oct 2;284(40):27185-94. doi: 10.1074/jbc.M109.026021. Epub 2009 Jul 29.

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