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Items: 1 to 50 of 238

1.

Adolescent exposure to Δ9-tetrahydrocannabinol delays acquisition of paired-associates learning in adulthood.

Abela AR, Rahbarnia A, Wood S, Lê AD, Fletcher PJ.

Psychopharmacology (Berl). 2019 Jan 29. doi: 10.1007/s00213-019-5171-1. [Epub ahead of print]

PMID:
30694374
2.
3.

Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition.

Browne CJ, Abela AR, Chu D, Li Z, Ji X, Lambe EK, Fletcher PJ.

Neuropsychopharmacology. 2019 Mar;44(4):793-804. doi: 10.1038/s41386-018-0271-x. Epub 2018 Nov 12.

PMID:
30420603
4.

Kappa opioid receptors mediate yohimbine-induced increases in impulsivity in the 5-choice serial reaction time task.

Funk D, Tamadon S, Coen K, Fletcher PJ, Lê AD.

Behav Brain Res. 2019 Feb 1;359:258-265. doi: 10.1016/j.bbr.2018.11.006. Epub 2018 Nov 8.

PMID:
30414973
5.

Objective investigation of activity preference in schizophrenia: A pilot study.

Siddiqui I, Remington G, Fervaha G, Fletcher PJ, Voineskos AN, Saperia S, Zakzanis KK, Foussias G.

Psychiatry Res. 2018 Sep;267:551-559. doi: 10.1016/j.psychres.2018.05.039. Epub 2018 May 16.

PMID:
29980136
6.

Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food.

Abela AR, Li Z, Lê AD, Fletcher PJ.

Addict Biol. 2018 Mar 25. doi: 10.1111/adb.12619. [Epub ahead of print]

PMID:
29575323
7.

Mortality and Readmission Following Hospitalisation for Heart Failure in Australia: A Systematic Review and Meta-Analysis.

Al-Omary MS, Davies AJ, Evans TJ, Bastian B, Fletcher PJ, Attia J, Boyle AJ.

Heart Lung Circ. 2018 Aug;27(8):917-927. doi: 10.1016/j.hlc.2018.01.009. Epub 2018 Feb 5. Review.

PMID:
29519691
8.

Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system.

Volle J, Bregman T, Scott B, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C.

Neuropharmacology. 2018 Jun;135:63-72. doi: 10.1016/j.neuropharm.2018.03.005. Epub 2018 Mar 2.

PMID:
29505786
9.

Preclinical evidence for combining the 5-HT2C receptor agonist lorcaserin and varenicline as a treatment for nicotine dependence.

Fletcher PJ, Li Z, Silenieks LB, MacMillan C, DeLannoy I, Higgins GA.

Addict Biol. 2018 Mar 2. doi: 10.1111/adb.12602. [Epub ahead of print]

PMID:
29498158
10.

Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.

Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR.

Front Pharmacol. 2018 Jan 4;8:924. doi: 10.3389/fphar.2017.00924. eCollection 2017.

11.

Outcomes following heart failure hospitalization in a regional Australian setting between 2005 and 2014.

Al-Omary MS, Khan AA, Davies AJ, Fletcher PJ, Mcivor D, Bastian B, Oldmeadow C, Sverdlov AL, Attia JR, Boyle AJ.

ESC Heart Fail. 2018 Apr;5(2):271-278. doi: 10.1002/ehf2.12239. Epub 2017 Dec 19.

12.

Deep brain stimulation induces antidepressant-like effects in serotonin transporter knockout mice.

Bregman T, Nona C, Volle J, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C.

Brain Stimul. 2018 Mar - Apr;11(2):423-425. doi: 10.1016/j.brs.2017.11.008. Epub 2017 Nov 15.

PMID:
29174865
13.

Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists.

Higgins GA, Zeeb FD, Fletcher PJ.

J Psychopharmacol. 2017 Nov;31(11):1403-1418. doi: 10.1177/0269881117735797. Epub 2017 Oct 26. Review.

PMID:
29072522
14.

Objective assessment of exploratory behaviour in schizophrenia using wireless motion capture.

Siddiqui I, Remington G, Fletcher PJ, Voineskos AN, Fong JW, Saperia S, Fervaha G, Da Silva S, Zakzanis KK, Foussias G.

Schizophr Res. 2018 May;195:122-129. doi: 10.1016/j.schres.2017.09.011. Epub 2017 Sep 24.

PMID:
28954705
15.
16.

Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice.

Browne CJ, Ji X, Higgins GA, Fletcher PJ, Harvey-Lewis C.

Neuropsychopharmacology. 2017 Oct;42(11):2178-2187. doi: 10.1038/npp.2017.124. Epub 2017 Jun 13.

17.

Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse.

Feldcamp LA, Boutros PC, Raymond R, Fletcher PJ, Nobrega JN, Wong AHC.

Transl Psychiatry. 2017 May 9;7(5):e1125. doi: 10.1038/tp.2017.85.

18.

Pre-hospital thrombolysis in ST-segment elevation myocardial infarction: a regional Australian experience.

Khan AA, Fletcher PJ, Boyle AJ.

Med J Aust. 2017 May 1;206(8):369-370. No abstract available.

PMID:
28446123
19.

Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101.

Higgins GA, Silenieks LB, Patrick A, De Lannoy IAM, Fletcher PJ, Parker LA, MacLusky NJ, Sullivan LC, Chavera TA, Berg KA.

ACS Chem Neurosci. 2017 May 17;8(5):1074-1084. doi: 10.1021/acschemneuro.6b00444. Epub 2017 Mar 24.

PMID:
28338324
20.

Acquisition of nicotine self-administration in amphetamine and phencyclidine models of schizophrenia: A role for stress?

Fletcher PJ, Li Z, Coen KM, Lê AD.

Schizophr Res. 2018 Apr;194:98-106. doi: 10.1016/j.schres.2017.02.028. Epub 2017 Mar 17.

PMID:
28318841
21.

Effects of 5-HT1A, 5-HT2A and 5-HT2C receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate.

Fletcher PJ, Zeeb FD, Browne CJ, Higgins GA, Soko AD.

Psychopharmacology (Berl). 2017 Mar;234(5):889-902. doi: 10.1007/s00213-017-4529-5. Epub 2017 Jan 18.

PMID:
28097374
22.

Heart Failure Hospitalisations in the Hunter New England Area Over 10 years. A Changing Trend.

Al-Omary MS, Davies AJ, Khan AA, McGee M, Bastian B, Leitch J, Attia J, Fletcher PJ, Boyle AJ.

Heart Lung Circ. 2017 Jun;26(6):627-630. doi: 10.1016/j.hlc.2016.10.005. Epub 2016 Nov 19.

PMID:
27916591
23.

Lipoic acid and haloperidol-induced vacuous chewing movements: Implications for prophylactic antioxidant use in tardive dyskinesia.

Lister J, Andreazza AC, Navaid B, Wilson VS, Teo C, Nesarajah Y, Wilson AA, Nobrega JN, Fletcher PJ, Remington G.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jan 4;72:23-29. doi: 10.1016/j.pnpbp.2016.08.010. Epub 2016 Aug 24.

PMID:
27565433
24.

Disruption of a dopamine receptor complex amplifies the actions of cocaine.

Perreault ML, Hasbi A, Shen MYF, Fan T, Navarro G, Fletcher PJ, Franco R, Lanciego JL, George SR.

Eur Neuropsychopharmacol. 2016 Sep;26(9):1366-1377. doi: 10.1016/j.euroneuro.2016.07.008. Epub 2016 Jul 30.

PMID:
27480020
25.

Pre-hospital thrombolysis in ST-segment elevation myocardial infarction: a regional Australian experience.

Khan AA, Williams T, Savage L, Stewart P, Ashraf A, Davies AJ, Faddy S, Attia J, Oldmeadow C, Bhagwandeen R, Fletcher PJ, Boyle AJ.

Med J Aust. 2016 Aug 1;205(3):121-5.

PMID:
27465767
26.

Mgat5 modulates the effect of early life stress on adult behavior and physical health in mice.

Feldcamp L, Doucet JS, Pawling J, Fadel MP, Fletcher PJ, Maunder R, Dennis JW, Wong AH.

Behav Brain Res. 2016 Oct 1;312:253-64. doi: 10.1016/j.bbr.2016.06.033. Epub 2016 Jun 18.

PMID:
27329152
27.

Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT2C receptor agonists.

Higgins GA, Silenieks LB, Altherr EB, MacMillan C, Fletcher PJ, Pratt WE.

Psychopharmacology (Berl). 2016 Jul;233(14):2841-56. doi: 10.1007/s00213-016-4329-3. Epub 2016 May 30.

PMID:
27241709
28.

Decreased Incentive Motivation Following Knockout or Acute Blockade of the Serotonin Transporter: Role of the 5-HT2C Receptor.

Browne CJ, Fletcher PJ.

Neuropsychopharmacology. 2016 Sep;41(10):2566-76. doi: 10.1038/npp.2016.63. Epub 2016 Apr 29.

29.

The adrenergic α2 antagonist atipamezole alters the behavioural effects of pramipexole and increases pramipexole concentration in blood plasma.

McCormick PN, Fletcher PJ, Wilson VS, Remington GJ.

Life Sci. 2016 Apr 15;151:300-304. doi: 10.1016/j.lfs.2016.03.017. Epub 2016 Mar 11.

PMID:
26976325
30.

Low Impulsive Action, but not Impulsive Choice, Predicts Greater Conditioned Reinforcer Salience and Augmented Nucleus Accumbens Dopamine Release.

Zeeb FD, Soko AD, Ji X, Fletcher PJ.

Neuropsychopharmacology. 2016 Jul;41(8):2091-100. doi: 10.1038/npp.2016.9. Epub 2016 Jan 19.

31.

Responding for a conditioned reinforcer or unconditioned sensory reinforcer in mice: interactions with environmental enrichment, social isolation, and monoamine reuptake inhibitors.

Browne CJ, Fletcher PJ, Zeeb FD.

Psychopharmacology (Berl). 2016 Mar;233(6):983-93. doi: 10.1007/s00213-015-4178-5. Epub 2015 Dec 22.

PMID:
26690588
32.

The 5-HT(2C) receptor agonist lorcaserin reduces cocaine self-administration, reinstatement of cocaine-seeking and cocaine induced locomotor activity.

Harvey-Lewis C, Li Z, Higgins GA, Fletcher PJ.

Neuropharmacology. 2016 Feb;101:237-45. doi: 10.1016/j.neuropharm.2015.09.028. Epub 2015 Sep 30.

PMID:
26427596
33.

Therapeutic Potential of 5-HT2C Receptor Agonists for Addictive Disorders.

Higgins GA, Fletcher PJ.

ACS Chem Neurosci. 2015 Jul 15;6(7):1071-88. doi: 10.1021/acschemneuro.5b00025. Epub 2015 Apr 14. Review.

PMID:
25870913
34.

The Serotonin 2C Receptor Agonist Lorcaserin Attenuates Intracranial Self-Stimulation and Blocks the Reward-Enhancing Effects of Nicotine.

Zeeb FD, Higgins GA, Fletcher PJ.

ACS Chem Neurosci. 2015 Jul 15;6(7):1231-40. doi: 10.1021/acschemneuro.5b00017. Epub 2015 Mar 17.

PMID:
25781911
35.

Characterization of the 5-HT2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet-induced obesity.

Higgins GA, Desnoyer J, Van Niekerk A, Silenieks LB, Lau W, Thevarkunnel S, Izhakova J, DeLannoy IA, Fletcher PJ, DeLay J, Dobson H.

Pharmacol Res Perspect. 2015 Feb;3(1):e00084. doi: 10.1002/prp2.84. Epub 2014 Nov 7.

36.

Behavioral effects of food-derived opioid-like peptides in rodents: Implications for schizophrenia?

Lister J, Fletcher PJ, Nobrega JN, Remington G.

Pharmacol Biochem Behav. 2015 Jul;134:70-8. doi: 10.1016/j.pbb.2015.01.020. Epub 2015 Feb 7. Review.

PMID:
25661529
37.

Antipsychotics and amotivation.

Fervaha G, Takeuchi H, Lee J, Foussias G, Fletcher PJ, Agid O, Remington G.

Neuropsychopharmacology. 2015 May;40(6):1539-48. doi: 10.1038/npp.2015.3. Epub 2015 Jan 8.

38.

A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects.

Su P, Li S, Chen S, Lipina TV, Wang M, Lai TK, Lee FH, Zhang H, Zhai D, Ferguson SS, Nobrega JN, Wong AH, Roder JC, Fletcher PJ, Liu F.

Neuron. 2014 Dec 17;84(6):1302-16. doi: 10.1016/j.neuron.2014.11.007. Epub 2014 Nov 26.

39.

Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforcer.

McCormick PN, Fletcher PJ, Wilson VS, Browne JD, Nobrega JN, Remington GJ.

Neuropharmacology. 2015 Feb;89:225-31. doi: 10.1016/j.neuropharm.2014.09.026. Epub 2014 Oct 13.

PMID:
25283483
40.

Examination of the effects of varenicline, bupropion, lorcaserin, or naltrexone on responding for conditioned reinforcement in nicotine-exposed rats.

Guy EG, Fisher DC, Higgins GA, Fletcher PJ.

Behav Pharmacol. 2014 Dec;25(8):775-83. doi: 10.1097/FBP.0000000000000092.

PMID:
25230208
41.
42.

Responding for conditioned reinforcement in C57BL/6 and CD-1 mice, and Sprague-Dawley rats: Effects of methylphenidate and amphetamine.

Browne JD, Soko AD, Fletcher PJ.

Psychopharmacology (Berl). 2014 Dec;231(23):4503-16. doi: 10.1007/s00213-014-3602-6. Epub 2014 May 8.

PMID:
24804572
43.

Oxidative stress and the antipsychotic-induced vacuous chewing movement model of tardive dyskinesia: evidence for antioxidant-based prevention strategies.

Lister J, Nobrega JN, Fletcher PJ, Remington G.

Psychopharmacology (Berl). 2014 Jun;231(11):2237-49. doi: 10.1007/s00213-014-3582-6. Epub 2014 Apr 22. Review.

PMID:
24752659
44.

Chronic exposure to a gambling-like schedule of reward predictive stimuli can promote sensitization to amphetamine in rats.

Zack M, Featherstone RE, Mathewson S, Fletcher PJ.

Front Behav Neurosci. 2014 Feb 11;8:36. doi: 10.3389/fnbeh.2014.00036. eCollection 2014.

45.

The effects of nicotine exposure during Pavlovian conditioning in rats on several measures of incentive motivation for a conditioned stimulus paired with water.

Guy EG, Fletcher PJ.

Psychopharmacology (Berl). 2014 Jun;231(11):2261-71. doi: 10.1007/s00213-013-3375-3. Epub 2013 Dec 7.

PMID:
24317443
46.

From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists.

Higgins GA, Sellers EM, Fletcher PJ.

Trends Pharmacol Sci. 2013 Oct;34(10):560-70. doi: 10.1016/j.tips.2013.08.001. Epub 2013 Sep 13. Review.

PMID:
24041919
47.

Pros, cons, and organization of prehospital thrombolysis.

Fletcher PJ, Stewart P, Savage L.

Clin Ther. 2013 Aug;35(8):1058-63. doi: 10.1016/j.clinthera.2013.07.425. Review.

PMID:
23973038
48.

Deep brain stimulation of the subthalamic nucleus increases premature responding in a rat gambling task.

Aleksandrova LR, Creed MC, Fletcher PJ, Lobo DS, Hamani C, Nobrega JN.

Behav Brain Res. 2013 May 15;245:76-82. doi: 10.1016/j.bbr.2013.02.011. Epub 2013 Feb 19.

PMID:
23434606
49.

Adolescent cocaine exposure causes enduring macroscale changes in mouse brain structure.

Wheeler AL, Lerch JP, Chakravarty MM, Friedel M, Sled JG, Fletcher PJ, Josselyn SA, Frankland PW.

J Neurosci. 2013 Jan 30;33(5):1797-803a. doi: 10.1523/JNEUROSCI.3830-12.2013.

50.

Antagonizing 5-HT₂A receptors with M100907 and stimulating 5-HT₂C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats.

Burton CL, Rizos Z, Diwan M, Nobrega JN, Fletcher PJ.

Behav Brain Res. 2013 Mar 1;240:171-81. doi: 10.1016/j.bbr.2012.11.030. Epub 2012 Nov 28.

PMID:
23201361

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