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Items: 1 to 50 of 76

1.

Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins.

Hennigan RF, Fletcher JS, Guard S, Ratner N.

Sci Signal. 2019 Apr 23;12(578). pii: eaau8749. doi: 10.1126/scisignal.aau8749.

PMID:
31015291
2.

Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice.

Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N.

JCI Insight. 2019 Feb 7;4(3). pii: 98601. doi: 10.1172/jci.insight.98601. [Epub ahead of print]

3.

STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma.

Fletcher JS, Springer MG, Choi K, Jousma E, Rizvi TA, Dombi E, Kim MO, Wu J, Ratner N.

Oncogene. 2019 Apr;38(15):2876-2884. doi: 10.1038/s41388-018-0600-x. Epub 2018 Dec 12.

4.

On-Tissue Chemical Derivatization of Catecholamines Using 4-( N-Methyl)pyridinium Boronic Acid for ToF-SIMS and LDI-ToF Mass Spectrometry Imaging.

Kaya I, Brülls SM, Dunevall J, Jennische E, Lange S, Mårtensson J, Ewing AG, Malmberg P, Fletcher JS.

Anal Chem. 2018 Nov 20;90(22):13580-13590. doi: 10.1021/acs.analchem.8b03746. Epub 2018 Nov 5.

PMID:
30346141
5.

Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues.

Porta Siegel T, Hamm G, Bunch J, Cappell J, Fletcher JS, Schwamborn K.

Mol Imaging Biol. 2018 Dec;20(6):888-901. doi: 10.1007/s11307-018-1267-y. Review.

6.

Benefits of NaCl addition for ToF-SIMS analysis including the discrimination of diacylglyceride and triacylglyceride ions.

Sämfors S, Ewing AG, Fletcher JS.

Rapid Commun Mass Spectrom. 2018 Jun 1. doi: 10.1002/rcm.8181. [Epub ahead of print]

PMID:
29856895
7.

Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila Brain.

Philipsen MH, Phan NTN, Fletcher JS, Malmberg P, Ewing AG.

ACS Chem Neurosci. 2018 Jun 20;9(6):1462-1468. doi: 10.1021/acschemneuro.8b00046. Epub 2018 Mar 20.

PMID:
29508991
8.

Chemical imaging of aggressive basal cell carcinoma using time-of-flight secondary ion mass spectrometry.

Munem M, Zaar O, Dimovska Nilsson K, Neittaanmäki N, Paoli J, Fletcher JS.

Biointerphases. 2018 Jan 12;13(3):03B402. doi: 10.1116/1.5016254.

PMID:
29329503
9.

MS/MS analysis and imaging of lipids across Drosophila brain using secondary ion mass spectrometry.

Phan NTN, Munem M, Ewing AG, Fletcher JS.

Anal Bioanal Chem. 2017 Jun;409(16):3923-3932. doi: 10.1007/s00216-017-0336-4. Epub 2017 Apr 7.

10.

An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system.

Choi K, Komurov K, Fletcher JS, Jousma E, Cancelas JA, Wu J, Ratner N.

Sci Rep. 2017 Mar 3;7:43315. doi: 10.1038/srep43315.

11.

Lipid Heterogeneity Resulting from Fatty Acid Processing in the Human Breast Cancer Microenvironment Identified by GCIB-ToF-SIMS Imaging.

Angerer TB, Magnusson Y, Landberg G, Fletcher JS.

Anal Chem. 2016 Dec 6;88(23):11946-11954. Epub 2016 Nov 9.

PMID:
27783898
12.

Cholesterol Alters the Dynamics of Release in Protein Independent Cell Models for Exocytosis.

Najafinobar N, Mellander LJ, Kurczy ME, Dunevall J, Angerer TB, Fletcher JS, Cans AS.

Sci Rep. 2016 Sep 21;6:33702. doi: 10.1038/srep33702.

13.

Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry.

Mohammadi AS, Phan NT, Fletcher JS, Ewing AG.

Anal Bioanal Chem. 2016 Sep;408(24):6857-68. doi: 10.1007/s00216-016-9812-5. Epub 2016 Aug 22.

14.

Investigating the Role of the Stringent Response in Lipid Modifications during the Stationary Phase in E. coli by Direct Analysis with Time-of-Flight-Secondary Ion Mass Spectrometry.

Wehrli PM, Angerer TB, Farewell A, Fletcher JS, Gottfries J.

Anal Chem. 2016 Sep 6;88(17):8680-8. doi: 10.1021/acs.analchem.6b01981. Epub 2016 Aug 12.

PMID:
27479574
15.

Multimodal Imaging of Chemically Fixed Cells in Preparation for NanoSIMS.

Lovrić J, Malmberg P, Johansson BR, Fletcher JS, Ewing AG.

Anal Chem. 2016 Sep 6;88(17):8841-8. doi: 10.1021/acs.analchem.6b02408. Epub 2016 Aug 9.

PMID:
27462909
16.

Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion Sources.

Yokoyama Y, Aoyagi S, Fujii M, Matsuo J, Fletcher JS, Lockyer NP, Vickerman JC, Passarelli MK, Havelund R, Seah MP.

Anal Chem. 2016 Apr 5;88(7):3592-7. doi: 10.1021/acs.analchem.5b04133. Epub 2016 Mar 9.

PMID:
26916620
17.

Optimizing sample preparation for anatomical determination in the hippocampus of rodent brain by ToF-SIMS analysis.

Angerer TB, Mohammadi AS, Fletcher JS.

Biointerphases. 2016 Jun 8;11(2):02A319. doi: 10.1116/1.4941064.

PMID:
26856332
18.

Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar clusters.

Nakano S, Yokoyama Y, Aoyagi S, Himi N, Fletcher JS, Lockyer NP, Henderson A, Vickerman JC.

Biointerphases. 2016 Jun 8;11(2):02A307. doi: 10.1116/1.4939251.

PMID:
26746166
19.

3D imaging of biological specimen using MS.

Fletcher JS.

Bioanalysis. 2015;7(20):2657-66. doi: 10.4155/bio.15.158. Epub 2015 Oct 29.

PMID:
26510971
20.

Correction to Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

Shard AG, Havelund R, Spencer SJ, Gilmore IS, Alexander MR, Angerer TB, Aoyagi S, Barnes JP, Benayad A, Bernasik A, Ceccone G, Counsell JD, Deeks C, Fletcher JS, Graham DJ, Heuser C, Lee TG, Marie C, Marzec MM, Mishra G, Rading D, Renault O, Scurr DJ, Shon HK, Spampinato V, Tian H, Wang F, Winograd N, Wu K, Wucher A, Zhou Y, Zhu Z, Cristaudo V, Poleunis C.

J Phys Chem B. 2015 Nov 5;119(44):14337. doi: 10.1021/acs.jpcb.5b09767. Epub 2015 Oct 15. No abstract available.

PMID:
26469795
21.

Significant enhancement of negative secondary ion yields by cluster ion bombardment combined with cesium flooding.

Philipp P, Angerer TB, Sämfors S, Blenkinsopp P, Fletcher JS, Wirtz T.

Anal Chem. 2015 Oct 6;87(19):10025-32. doi: 10.1021/acs.analchem.5b02635.

PMID:
26378890
22.

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

Shard AG, Havelund R, Spencer SJ, Gilmore IS, Alexander MR, Angerer TB, Aoyagi S, Barnes JP, Benayad A, Bernasik A, Ceccone G, Counsell JD, Deeks C, Fletcher JS, Graham DJ, Heuser C, Lee TG, Marie C, Marzec MM, Mishra G, Rading D, Renault O, Scurr DJ, Shon HK, Spampinato V, Tian H, Wang F, Winograd N, Wu K, Wucher A, Zhou Y, Zhu Z, Cristaudo V, Poleunis C.

J Phys Chem B. 2015 Aug 20;119(33):10784-97. doi: 10.1021/acs.jpcb.5b05625. Epub 2015 Aug 6. Erratum in: J Phys Chem B. 2015 Nov 5;119(44):14337. Cristaudo, Vanina [added]; Poleunis, Claude [added].

PMID:
26204428
23.

ToF-SIMS imaging of lipids and lipid related compounds in Drosophila brain.

Phan NT, Fletcher JS, Sjövall P, Ewing AG.

Surf Interface Anal. 2014 Nov;46(Suppl 1):123-126.

24.

Analysis of liposome model systems by time-of-flight secondary ion mass spectrometry.

Lovrić J, Keighron JD, Angerer TB, Li X, Malmberg P, Fletcher JS, Ewing AG.

Surf Interface Anal. 2014 Nov;46(Suppl 1):74-78.

25.

Lipid structural effects of oral administration of methylphenidate in Drosophila brain by secondary ion mass spectrometry imaging.

Phan NT, Fletcher JS, Ewing AG.

Anal Chem. 2015 Apr 21;87(8):4063-71. doi: 10.1021/acs.analchem.5b00555. Epub 2015 Apr 13.

PMID:
25856152
26.

Improved molecular imaging in rodent brain with time-of-flight-secondary ion mass spectrometry using gas cluster ion beams and reactive vapor exposure.

Angerer TB, Dowlatshahi Pour M, Malmberg P, Fletcher JS.

Anal Chem. 2015 Apr 21;87(8):4305-13. doi: 10.1021/ac504774y. Epub 2015 Apr 2.

PMID:
25799886
27.

Latest applications of 3D ToF-SIMS bio-imaging.

Fletcher JS.

Biointerphases. 2015 Mar 10;10(1):018902. doi: 10.1116/1.4907727. Review.

PMID:
25708631
28.

Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic ToF-SIMS imaging.

Tian H, Fletcher JS, Thuret R, Henderson A, Papalopulu N, Vickerman JC, Lockyer NP.

J Lipid Res. 2014 Sep;55(9):1970-80. doi: 10.1194/jlr.D048660. Epub 2014 May 22.

29.

Time-of-flight secondary ion mass spectrometry based molecular histology of human spinal cord tissue and motor neurons.

Hanrieder J, Malmberg P, Lindberg OR, Fletcher JS, Ewing AG.

Anal Chem. 2013 Sep 17;85(18):8741-8. doi: 10.1021/ac401830m. Epub 2013 Aug 27.

30.

Peptide structural analysis using continuous Ar cluster and C60 ion beams.

Aoyagi S, Fletcher JS, Sheraz Rabbani S, Kawashima T, Berrueta Razo I, Henderson A, Lockyer NP, Vickerman JC.

Anal Bioanal Chem. 2013 Aug;405(21):6621-8. doi: 10.1007/s00216-013-7139-z. Epub 2013 Jul 9.

PMID:
23836082
31.

Enhancing secondary ion yields in time of flight-secondary ion mass spectrometry using water cluster primary beams.

Sheraz née Rabbani S, Barber A, Fletcher JS, Lockyer NP, Vickerman JC.

Anal Chem. 2013 Jun 18;85(12):5654-8. doi: 10.1021/ac4013732. Epub 2013 May 31.

32.

The inherent problem of transflection-mode infrared spectroscopic microscopy and the ramifications for biomedical single point and imaging applications.

Bassan P, Lee J, Sachdeva A, Pissardini J, Dorling KM, Fletcher JS, Henderson A, Gardner P.

Analyst. 2013 Jan 7;138(1):144-57. doi: 10.1039/c2an36090j. Epub 2012 Oct 26.

PMID:
23099638
33.

Secondary ion mass spectrometry: characterizing complex samples in two and three dimensions.

Fletcher JS, Vickerman JC.

Anal Chem. 2013 Jan 15;85(2):610-39. doi: 10.1021/ac303088m. Epub 2012 Nov 8. Review. No abstract available.

PMID:
23094968
34.

Label free biochemical 2D and 3D imaging using secondary ion mass spectrometry.

Fletcher JS, Vickerman JC, Winograd N.

Curr Opin Chem Biol. 2011 Oct;15(5):733-40. doi: 10.1016/j.cbpa.2011.05.016. Epub 2011 Jun 12. Review.

35.

TOF-SIMS with argon gas cluster ion beams: a comparison with C60+.

Rabbani S, Barber AM, Fletcher JS, Lockyer NP, Vickerman JC.

Anal Chem. 2011 May 15;83(10):3793-800. doi: 10.1021/ac200288v. Epub 2011 Apr 15.

PMID:
21462969
36.

Three-dimensional mass spectral imaging of HeLa-M cells--sample preparation, data interpretation and visualisation.

Fletcher JS, Rabbani S, Henderson A, Lockyer NP, Vickerman JC.

Rapid Commun Mass Spectrom. 2011 Apr 15;25(7):925-32. doi: 10.1002/rcm.4944. Epub 2011 Mar 14.

PMID:
21416529
37.

Effects of cryogenic sample analysis on molecular depth profiles with TOF-secondary ion mass spectrometry.

Piwowar AM, Fletcher JS, Kordys J, Lockyer NP, Winograd N, Vickerman JC.

Anal Chem. 2010 Oct 1;82(19):8291-9. doi: 10.1021/ac101746h.

PMID:
20836508
38.

Analysis of messenger RNA expression by in situ hybridization using RNA probes synthesized via in vitro transcription.

Carter BS, Fletcher JS, Thompson RC.

Methods. 2010 Dec;52(4):322-31. doi: 10.1016/j.ymeth.2010.08.001. Epub 2010 Aug 10.

39.

Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap system.

Lanekoff I, Kurczy ME, Hill R, Fletcher JS, Vickerman JC, Winograd N, Sjövall P, Ewing AG.

Anal Chem. 2010 Aug 1;82(15):6652-9. doi: 10.1021/ac101243b.

40.

Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions.

Fletcher JS, Lockyer NP, Vickerman JC.

Mass Spectrom Rev. 2011 Jan-Feb;30(1):142-74. doi: 10.1002/mas.20275. Review.

PMID:
20077559
41.

Explanatory multivariate analysis of ToF-SIMS spectra for the discrimination of bacterial isolates.

Vaidyanathan S, Fletcher JS, Jarvis RM, Henderson A, Lockyer NP, Goodacre R, Vickerman JC.

Analyst. 2009 Nov;134(11):2352-60. doi: 10.1039/b907570d. Epub 2009 Sep 14.

PMID:
19838426
42.

Cellular imaging with secondary ion mass spectrometry.

Fletcher JS.

Analyst. 2009 Nov;134(11):2204-15. doi: 10.1039/b913575h. Epub 2009 Sep 24. Review.

PMID:
19838405
43.

A new SIMS paradigm for 2D and 3D molecular imaging of bio-systems.

Fletcher JS, Vickerman JC.

Anal Bioanal Chem. 2010 Jan;396(1):85-104. doi: 10.1007/s00216-009-2986-3. Epub 2009 Aug 12. Review.

PMID:
19669735
44.

A new dynamic in mass spectral imaging of single biological cells.

Fletcher JS, Rabbani S, Henderson A, Blenkinsopp P, Thompson SP, Lockyer NP, Vickerman JC.

Anal Chem. 2008 Dec 1;80(23):9058-64. doi: 10.1021/ac8015278.

PMID:
19551933
45.

Ecological recovery of vegetation at a former industrial sludge basin and its implications to phytoremediation.

Olson PE, Fletcher JS.

Environ Sci Pollut Res Int. 2000;7(4):195-204. doi: 10.1007/BF02987348.

PMID:
19005834
46.

Subsurface biomolecular imaging of Streptomyces coelicolor using secondary ion mass spectrometry.

Vaidyanathan S, Fletcher JS, Goodacre R, Lockyer NP, Micklefield J, Vickerman JC.

Anal Chem. 2008 Mar 15;80(6):1942-51. doi: 10.1021/ac701921e. Epub 2008 Feb 22.

PMID:
18290669
47.

Properties of C84 and C24H12 molecular ion sources for routine TOF-SIMS analysis.

Biddulph GX, Piwowar AM, Fletcher JS, Lockyer NP, Vickerman JC.

Anal Chem. 2007 Oct 1;79(19):7259-66. Epub 2007 Sep 7.

PMID:
17822312
48.

TOF-SIMS 3D biomolecular imaging of Xenopus laevis oocytes using buckminsterfullerene (C60) primary ions.

Fletcher JS, Lockyer NP, Vaidyanathan S, Vickerman JC.

Anal Chem. 2007 Mar 15;79(6):2199-206. Epub 2007 Feb 16.

PMID:
17302385
49.

Polychlorinated biphenyl (PCB)-degrading bacteria associated with trees in a PCB-contaminated site.

Leigh MB, Prouzová P, Macková M, Macek T, Nagle DP, Fletcher JS.

Appl Environ Microbiol. 2006 Apr;72(4):2331-42.

50.

TOF-SIMS analysis using C60. Effect of impact energy on yield and damage.

Fletcher JS, Conlan XA, Jones EA, Biddulph G, Lockyer NP, Vickerman JC.

Anal Chem. 2006 Mar 15;78(6):1827-31.

PMID:
16536417

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