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Items: 1 to 50 of 129

1.

Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation.

Govier-Cole AE, Wood RJ, Fletcher JL, Gonsalvez DG, Merlo D, Cate HS, Murray SS, Xiao J.

eNeuro. 2019 May 14;6(2). pii: ENEURO.0399-18.2019. doi: 10.1523/ENEURO.0399-18.2019. Print 2019 Mar/Apr.

2.

Very early ART initiation during acute HIV infection is associated with normalization of cerebrospinal fluid but not plasma markers of immune activation.

Hellmuth J, Slike BM, Sacdalan C, Best J, Kroon E, Phanuphak N, Fletcher JLK, Prueksakaew P, Jagodzinski LL, Valcour V, Robb M, Ananworanich J, Allen IE, Krebs SJ, Spudich S; SEARCH 010/RV254 and SEARCH013/RV304 Study Groups.

J Infect Dis. 2019 Jan 21. doi: 10.1093/infdis/jiz030. [Epub ahead of print]

PMID:
30668739
3.

Brain-Derived Neurotrophic Factor in Central Nervous System Myelination: A New Mechanism to Promote Myelin Plasticity and Repair.

Fletcher JL, Murray SS, Xiao J.

Int J Mol Sci. 2018 Dec 19;19(12). pii: E4131. doi: 10.3390/ijms19124131. Review.

4.

Structural and functional brain imaging in acute HIV.

Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V; SEARCH 010/RV254; RV304 protocol teams.

Neuroimage Clin. 2018 Jul 27;20:327-335. doi: 10.1016/j.nicl.2018.07.024. eCollection 2018.

5.

Myelin Protein Zero180-199 Peptide Induced Experimental Autoimmune Neuritis in C57BL/6 Mice.

Gonsalvez DG, Yoo S, Craig GA, Wood RJ, Fletcher JL, Murray SS, Xiao J.

Methods Mol Biol. 2018;1791:243-250. doi: 10.1007/978-1-4939-7862-5_19.

PMID:
30006715
6.

Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain.

Fletcher JL, Wood RJ, Nguyen J, Norman EML, Jun CMK, Prawdiuk AR, Biemond M, Nguyen HTH, Northfield SE, Hughes RA, Gonsalvez DG, Xiao J, Murray SS.

J Neurosci. 2018 Aug 8;38(32):7088-7099. doi: 10.1523/JNEUROSCI.0487-18.2018. Epub 2018 Jul 5.

7.

BDNF haploinsufficiency exerts a transient and regionally different influence upon oligodendroglial lineage cells during postnatal development.

Nicholson M, Wood RJ, Fletcher JL, van den Buuse M, Murray SS, Xiao J.

Mol Cell Neurosci. 2018 May 18;90:12-21. doi: 10.1016/j.mcn.2018.05.005. [Epub ahead of print]

PMID:
29782918
8.

Characterization of Cellular Immune Responses in Thai Individuals With and Without HIV-Associated Neurocognitive Disorders.

Ratto-Kim S, Schuetz A, Sithinamsuwan P, Barber J, Hutchings N, Lerdlum S, Fletcher JLK, Phuang-Ngern Y, Chuenarom W, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Sajjaweerawan C, Akapirat S, Chalermchai T, Suttichom D, Kaewboon B, Prueksakaew P, Karnsomlap P, Clifford D, Paul RH, de Souza MS, Kim JH, Ananworanich J, Valcour V.

AIDS Res Hum Retroviruses. 2018 Aug;34(8):685-689. doi: 10.1089/AID.2017.0237. Epub 2018 Jun 12.

PMID:
29737194
9.

Preinjury statin use and thromboembolic events in trauma: a 10-year retrospective evaluation.

McMahon RA, Fletcher JL, Aden JK, Holland SR, Trexler ST, Blackbourne LH.

J Surg Res. 2018 Jun;226:100-111. doi: 10.1016/j.jss.2017.12.018. Epub 2018 Feb 22.

PMID:
29661275
10.

Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.

Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group .

Clin Infect Dis. 2018 May 2;66(10):1540-1549. doi: 10.1093/cid/cix1063.

11.

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments.

Gonsalvez DG, Fletcher JL, Yoo SW, Wood RJ, Murray SS, Xiao J.

J Vis Exp. 2017 Nov 9;(129). doi: 10.3791/56455.

PMID:
29155769
12.

Accelerated epithelialization and improved wound healing metrics in porcine full-thickness wounds transplanted with full-thickness skin micrografts.

Rettinger CL, Fletcher JL, Carlsson AH, Chan RK.

Wound Repair Regen. 2017 Sep;25(5):816-827. doi: 10.1111/wrr.12585. Epub 2017 Oct 11.

PMID:
28922518
13.

Effectiveness of fluticasone furoate plus vilanterol on asthma control in clinical practice: an open-label, parallel group, randomised controlled trial.

Woodcock A, Vestbo J, Bakerly ND, New J, Gibson JM, McCorkindale S, Jones R, Collier S, Lay-Flurrie J, Frith L, Jacques L, Fletcher JL, Harvey C, Svedsater H, Leather D; Salford Lung Study Investigators.

Lancet. 2017 Nov 18;390(10109):2247-2255. doi: 10.1016/S0140-6736(17)32397-8. Epub 2017 Sep 10. Erratum in: Lancet. 2017 Nov 18;390(10109):e40. Lancet. 2018 Feb 3;391(10119):430.

PMID:
28903864
14.

Factors associated with intention to take non-occupational HIV post-exposure prophylaxis among Thai men who have sex with men.

Chomchey N, Woratanarat T, Hiransuthikul N, Lertmaharit S, Lohsoonthorn V, Teeratakulpisarn N, Pinyakorn S, Fletcher JL, Suttichom D, Phanuphak P, Ananworanich J, Phanuphak N.

J Virus Erad. 2017 Jul 1;3(3):128-139.

15.

Acute HIV infection detection and immediate treatment estimated to reduce transmission by 89% among men who have sex with men in Bangkok.

Kroon EDMB, Phanuphak N, Shattock AJ, Fletcher JLK, Pinyakorn S, Chomchey N, Akapirat S, de Souza MS, Robb ML, Kim JH, van Griensven F, Ananworanich J, Wilson DP.

J Int AIDS Soc. 2017 Jun 28;20(1):21708. doi: 10.7448/IAS.20.1.21708.

16.

Viral kinetics in untreated versus treated acute HIV infection in prospective cohort studies in Thailand.

Ananworanich J, Eller LA, Pinyakorn S, Kroon E, Sriplenchan S, Fletcher JL, Suttichom D, Bryant C, Trichavaroj R, Dawson P, Michael N, Phanuphak N, Robb ML.

J Int AIDS Soc. 2017 Jun 26;20(1):21652. doi: 10.7448/IAS.20.1.21652.

17.

A Brain-Derived Neurotrophic Factor-Based p75NTR Peptide Mimetic Ameliorates Experimental Autoimmune Neuritis Induced Axonal Pathology and Demyelination.

Gonsalvez DG, Tran G, Fletcher JL, Hughes RA, Hodgkinson S, Wood RJ, Yoo SW, De Silva M, Agnes WW, McLean C, Kennedy P, Kilpatrick TJ, Murray SS, Xiao J.

eNeuro. 2017 Jul 4;4(3). pii: ENEURO.0142-17.2017. doi: 10.1523/ENEURO.0142-17.2017. eCollection 2017 May-Jun.

18.

Ultrahigh dose gentamicin alters inflammation and angiogenesis in vivo and in vitro.

Olekson MA, Rose LF, Carlsson AH, Fletcher JL, Leung KP, Chan RK.

Wound Repair Regen. 2017 Aug;25(4):632-640. doi: 10.1111/wrr.12557. Epub 2017 Jul 10.

PMID:
28665034
19.

Delayed differentiation of potent effector CD8+ T cells reducing viremia and reservoir seeding in acute HIV infection.

Takata H, Buranapraditkun S, Kessing C, Fletcher JL, Muir R, Tardif V, Cartwright P, Vandergeeten C, Bakeman W, Nichols CN, Pinyakorn S, Hansasuta P, Kroon E, Chalermchai T, O'Connell R, Kim J, Phanuphak N, Robb ML, Michael NL, Chomont N, Haddad EK, Ananworanich J, Trautmann L; RV254/SEARCH010 and the RV304/SEARCH013 Study Groups.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaag1809. doi: 10.1126/scitranslmed.aag1809.

20.

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection.

Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Takata H, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee S, Zetterberg H, Hellmuth J, Phanuphak N, Robb ML, Michael NL, Ananworanich J, Trautmann L.

J Acquir Immune Defic Syndr. 2017 May 1;75(1):108-117. doi: 10.1097/QAI.0000000000001301.

21.

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S; RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study Teams.

AIDS. 2017 Jan 14;31(2):247-252. doi: 10.1097/QAD.0000000000001314.

22.

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.

Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS; RV254/SEARCH 010, RV304/SEARCH 013 and SEARCH 011 protocol teams.

Clin Infect Dis. 2017 Jan 15;64(2):124-131. doi: 10.1093/cid/ciw683. Epub 2016 Oct 12.

23.

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.

Crowell TA, Fletcher JL, Sereti I, Pinyakorn S, Dewar R, Krebs SJ, Chomchey N, Rerknimitr R, Schuetz A, Michael NL, Phanuphak N, Chomont N, Ananworanich J; RV254/SEARCH010 Study Group.

J Int AIDS Soc. 2016 Sep 15;19(1):21163. doi: 10.7448/IAS.19.1.21163. eCollection 2016.

24.

Antecedent thermal injury worsens split-thickness skin graft quality: A clinically relevant porcine model of full-thickness burn, excision and grafting.

Carlsson AH, Rose LF, Fletcher JL, Wu JC, Leung KP, Chan RK.

Burns. 2017 Feb;43(1):223-231. doi: 10.1016/j.burns.2016.08.006. Epub 2016 Sep 3.

PMID:
27600980
25.

Therapy Development for the Lysosomal Storage Disease Fucosidosis using the Canine Animal Model.

Fletcher JL, Taylor RM.

Pediatr Endocrinol Rev. 2016 Jun;13 Suppl 1:697-706. Review.

PMID:
27491218
26.

HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART.

Ananworanich J, Chomont N, Eller LA, Kroon E, Tovanabutra S, Bose M, Nau M, Fletcher JLK, Tipsuk S, Vandergeeten C, O'Connell RJ, Pinyakorn S, Michael N, Phanuphak N, Robb ML; RV217 and RV254/SEARCH010 study groups.

EBioMedicine. 2016 Sep;11:68-72. doi: 10.1016/j.ebiom.2016.07.024. Epub 2016 Jul 20.

27.

Impact of early cART in the gut during acute HIV infection.

Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, Schacker TW, Hunt P, Lifson JD, Ananworanich J, Estes JD.

JCI Insight. 2016 Jul 7;1(10). pii: e87065.

28.

Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology.

de Souza MS, Pinyakorn S, Akapirat S, Pattanachaiwit S, Fletcher JL, Chomchey N, Kroon ED, Ubolyam S, Michael NL, Robb ML, Phanuphak P, Kim JH, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group.

Clin Infect Dis. 2016 Aug 15;63(4):555-61. doi: 10.1093/cid/ciw365. Epub 2016 Jun 17.

PMID:
27317797
29.

Neurologic signs and symptoms frequently manifest in acute HIV infection.

Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S; SEARCH 010/RV254 Study Group.

Neurology. 2016 Jul 12;87(2):148-54. doi: 10.1212/WNL.0000000000002837. Epub 2016 Jun 10.

30.

Virologic failure is uncommon after treatment initiation during acute HIV infection.

Crowell TA, Phanuphak N, Pinyakorn S, Kroon E, Fletcher JL, Colby D, Tipsuk S, Karnsomlap P, Laopraynak N, O'Connell RJ, Robb ML, Ananworanich J; RV254SEARCH010 Study Group.

AIDS. 2016 Jul 31;30(12):1943-50. doi: 10.1097/QAD.0000000000001148.

PMID:
27163706
31.

Retinoic Acid Receptor γ Regulates B and T Lymphopoiesis via Nestin-Expressing Cells in the Bone Marrow and Thymic Microenvironments.

Joseph C, Nota C, Fletcher JL, Maluenda AC, Green AC, Purton LE.

J Immunol. 2016 Mar 1;196(5):2132-44. doi: 10.4049/jimmunol.1501246. Epub 2016 Feb 3.

32.

Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification.

Ananworanich J, Chomont N, Fletcher JL, Pinyakorn S, Schuetz A, Sereti I, Rerknimitr R, Dewar R, Kroon E, Vandergeeten C, Trichavaroj R, Chomchey N, Chalermchai T, Michael NL, Kim JH, Phanuphak P, Phanuphak N.

J Virus Erad. 2015;1(2):116-122. Epub 2015 Apr 1.

33.

Associations between neurologic dysfunction and lesions in canine fucosidosis.

Fletcher JL, Taylor RM.

Genes Brain Behav. 2016 Apr;15(4):420-8. doi: 10.1111/gbb.12282. Epub 2016 Jan 22.

34.

Reverse posterior interosseous flap for defects of the dorsal ulnar wrist using previously burned and recently grafted skin.

Baylan JM, Chambers JA, McMullin N, Fletcher JL, Sinha I, Lundy J, King BT, Chan RK.

Burns. 2016 Mar;42(2):e24-30. doi: 10.1016/j.burns.2015.06.020. Epub 2015 Dec 2.

PMID:
26652146
35.

Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV.

Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J; SEARCH 010/RV 254 Study Group.

PLoS One. 2015 Nov 10;10(11):e0142600. doi: 10.1371/journal.pone.0142600. eCollection 2015.

36.

The effects of intracisternal enzyme replacement versus sham treatment on central neuropathology in preclinical canine fucosidosis.

Kondagari GS, Fletcher JL, Cruz R, Williamson P, Hopwood JJ, Taylor RM.

Orphanet J Rare Dis. 2015 Nov 4;10:143. doi: 10.1186/s13023-015-0357-z.

37.

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy.

Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S; RV254/SEARCH 010 Study Group.

J Acquir Immune Defic Syndr. 2015 Dec 1;70(4):393-9. doi: 10.1097/QAI.0000000000000746.

38.

Inability to determine tissue health is main indication of allograft use in intermediate extent burns.

Fletcher JL, Cancio LC, Sinha I, Leung KP, Renz EM, Chan RK.

Burns. 2015 Dec;41(8):1862-1867. doi: 10.1016/j.burns.2015.09.006. Epub 2015 Oct 23.

PMID:
26471053
39.

Neuronal-Glia Markers by Magnetic Resonance Spectroscopy in HIV Before and After Combination Antiretroviral Therapy.

Sailasuta N, Ananworanich J, Lerdlum S, Sithinamsuwan P, Fletcher JL, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Chalermchai T, Catella S, Busovaca E, Desai A, Paul R, Valcour V; SEARCH 011 Study Group.

J Acquir Immune Defic Syndr. 2016 Jan 1;71(1):24-30. doi: 10.1097/QAI.0000000000000779.

40.

Absence of Cerebrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection.

Peluso MJ, Valcour V, Ananworanich J, Sithinamsuwan P, Chalermchai T, Fletcher JL, Lerdlum S, Chomchey N, Slike B, Sailasuta N, Gisslén M, Zetterberg H, Spudich S; RV254/SEARCH 010 and SEARCH 011 Study Teams.

J Infect Dis. 2015 Dec 1;212(11):1759-67. doi: 10.1093/infdis/jiv296. Epub 2015 May 20.

41.

Impact of nucleic acid testing relative to antigen/antibody combination immunoassay on the detection of acute HIV infection.

De Souza MS, Phanuphak N, Pinyakorn S, Trichavaroj R, Pattanachaiwit S, Chomchey N, Fletcher JL, Kroon ED, Michael NL, Phanuphak P, Kim JH, Ananworanich J; RV254SEARCH 010 Study Group.

AIDS. 2015 Apr 24;29(7):793-800. doi: 10.1097/QAD.0000000000000616.

PMID:
25985402
42.

Anogenital HIV RNA in Thai men who have sex with men in Bangkok during acute HIV infection and after randomization to standard vs. intensified antiretroviral regimens.

Phanuphak N, Teeratakulpisarn N, van Griensven F, Chomchey N, Pinyakorn S, Fletcher JL, Trichavaroj R, Pattanachaiwit S, Michael N, Phanuphak P, Kim JH, Ananworanich J; RV254/SEARCH 010 Study Group.

J Int AIDS Soc. 2015 May 7;18:19470. doi: 10.7448/IAS.18.1.19470. eCollection 2015.

43.

Association between brain volumes and HAND in cART-naïve HIV+ individuals from Thailand.

Heaps JM, Sithinamsuwan P, Paul R, Lerdlum S, Pothisri M, Clifford D, Tipsuk S, Catella S, Busovaca E, Fletcher JL, Raudabaugh B, Ratto-Kim S, Valcour V, Ananworanich J; SEARCH 007/011 study groups.

J Neurovirol. 2015 Apr;21(2):105-12. doi: 10.1007/s13365-014-0309-8. Epub 2015 Jan 21.

44.

High prevalence of transmitted drug resistance in acute HIV-infected Thai men who have sex with men.

Ananworanich J, Sirivichayakul S, Pinyakorn S, Crowell TA, Trichavaroj R, Weerayingyong J, Chomchey N, Fletcher JL, van Griensven F, Phanuphak P, Robb ML, Michael NL, Kim JH, Phanuphak N.

J Acquir Immune Defic Syndr. 2015 Apr 1;68(4):481-5. doi: 10.1097/QAI.0000000000000502.

PMID:
25559593
45.

Practice effect and normative data of an HIV-specific neuropsychological testing battery among healthy Thais.

Sithinamsuwan P, Hutchings N, Ananworanich J, Wendelken L, Saengtawan P, Paul R, Chomchey N, Fletcher JL, Chalermchai T, Valcour V.

J Med Assoc Thai. 2014 Feb;97 Suppl 2:S222-33.

46.

HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy.

Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J; SEARCH 011 study group.

AIDS. 2014 Jul 17;28(11):1619-24. doi: 10.1097/QAD.0000000000000306.

47.

Oligodendrocyte loss during the disease course in a canine model of the lysosomal storage disease fucosidosis.

Fletcher JL, Kondagari GS, Vite CH, Williamson P, Taylor RM.

J Neuropathol Exp Neurol. 2014 Jun;73(6):536-47. doi: 10.1097/NEN.0000000000000075.

48.

Acute tubular nephropathy in a patient with acute HIV infection: review of the literature.

Ananworanich J, Datta AA, Fletcher JL, Townamchai N, Chomchey N, Kroon E, Sereti I, Valcour V, Kim JH.

AIDS Res Ther. 2014 Nov 7;11:34. doi: 10.1186/1742-6405-11-34. eCollection 2014.

49.

HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients.

Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B; SEARCH 011 Protocol Team.

PLoS One. 2013 Jul 31;8(7):e70164. doi: 10.1371/journal.pone.0070164. Print 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/18c308ec-1cff-4e93-b4bb-6c9fc3a25a15.

50.

A novel acute HIV infection staging system based on 4th generation immunoassay.

Ananworanich J, Fletcher JL, Pinyakorn S, van Griensven F, Vandergeeten C, Schuetz A, Pankam T, Trichavaroj R, Akapirat S, Chomchey N, Phanuphak P, Chomont N, Michael NL, Kim JH, de Souza M; RV254/SEARCH 010 Study Group.

Retrovirology. 2013 May 29;10:56. doi: 10.1186/1742-4690-10-56.

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