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Correction: In Porphyromonas gingivalis VimF Is Involved in Gingipain Maturation through the Transfer of Galactose.

Muthiah AS, Aruni W, Robles AG, Dou Y, Roy F, Fletcher HM.

PLoS One. 2019 Sep 23;14(9):e0223145. doi: 10.1371/journal.pone.0223145. eCollection 2019.


Health in the 2030 Agenda for Sustainable Development: from framework to action, transforming challenges into opportunities.

Dietler D, Leuenberger A, Bempong NE, Campbell-Lendrum D, Cramer C, Eggen RIL, Erismann S, Ferazzi S, Flahault A, Fletcher HA, Fuhrer B, Fuhrimann S, Greter H, Heerdegen AC, Leach M, Leissing A, Lilje J, Penny MA, Prytherch H, Staudacher P, Vounatsou P, Weiss F, Wiedemann R, Winkler MS, Zhou XN, Utzinger J.

J Glob Health. 2019 Dec;9(2):020201. doi: 10.7189/jogh.09.020201. No abstract available.


Are people with an intellectual disability at increased risk of attachment difficulties? A critical review.

Hamadi L, Fletcher HK.

J Intellect Disabil. 2019 Jul 30:1744629519864772. doi: 10.1177/1744629519864772. [Epub ahead of print]


How can we improve priority-setting for investments in health research? A case study of tuberculosis.

Khan MS, Rahman-Shepherd A, Painter H, Fletcher H.

Health Res Policy Syst. 2019 Jul 19;17(1):68. doi: 10.1186/s12961-019-0473-7.


RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice.

Prabowo SA, Painter H, Zelmer A, Smith SG, Seifert K, Amat M, Cardona PJ, Fletcher HA.

Front Immunol. 2019 Apr 30;10:894. doi: 10.3389/fimmu.2019.00894. eCollection 2019.


In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection.

Lee H, Kim J, Kang YA, Kim DR, Sim B, Zelmer A, Fletcher HA, Dockrell HM, Smith SG, Cho SN.

Front Immunol. 2019 Apr 26;10:896. doi: 10.3389/fimmu.2019.00896. eCollection 2019.


Author Correction: The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2019 Apr 3;9(1):5596. doi: 10.1038/s41598-019-41387-8.


Methods of Cough Assessment.

Cho PSP, Birring SS, Fletcher HV, Turner RD.

J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1715-1723. doi: 10.1016/j.jaip.2019.01.049. Epub 2019 Mar 27. Review.


Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells.

Prabowo SA, Zelmer A, Stockdale L, Ojha U, Smith SG, Seifert K, Fletcher HA.

Sci Rep. 2019 Mar 19;9(1):4842. doi: 10.1038/s41598-019-41008-4.


Differences in monocyte: lymphocyte ratio and Tuberculosis disease progression in genetically distinct populations of macaques.

Sibley L, Gooch K, Wareham A, Gray S, Chancellor A, Dowall S, Bate S, Marriott A, Dennis M, White AD, Marsh PD, Fletcher H, Sharpe S.

Sci Rep. 2019 Mar 4;9(1):3340. doi: 10.1038/s41598-019-39819-6.


Impaired cough suppression in chronic refractory cough.

Cho PSP, Fletcher HV, Turner RD, Jolley CJ, Birring SS.

Eur Respir J. 2019 May 2;53(5). pii: 1802203. doi: 10.1183/13993003.02203-2018. Print 2019 May.


Household air pollution in Nairobi's slums: A long-term policy evaluation using participatory system dynamics.

Dianati K, Zimmermann N, Milner J, Muindi K, Ezeh A, Chege M, Mberu B, Kyobutungi C, Fletcher H, Wilkinson P, Davies M.

Sci Total Environ. 2019 Apr 10;660:1108-1134. doi: 10.1016/j.scitotenv.2018.12.430. Epub 2019 Jan 6.


Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin.

McNeill E, Stylianou E, Crabtree MJ, Harrington-Kandt R, Kolb AL, Diotallevi M, Hale AB, Bettencourt P, Tanner R, O'Shea MK, Matsumiya M, Lockstone H, Müller J, Fletcher HA, Greaves DR, McShane H, Channon KM.

Nat Commun. 2018 Dec 20;9(1):5409. doi: 10.1038/s41467-018-07714-9.


HIV, HCMV and mycobacterial antibody levels: a cross-sectional study in a rural Ugandan cohort.

Stockdale L, Nash S, Nalwoga A, Gibson L, Painter H, Raynes J, Asiki G, Newton R, Fletcher H.

Trop Med Int Health. 2019 Feb;24(2):247-257. doi: 10.1111/tmi.13188. Epub 2018 Dec 27.


Systems approaches to correlates of protection and progression to TB disease.

Fletcher HA.

Semin Immunol. 2018 Oct;39:81-87. doi: 10.1016/j.smim.2018.10.001. Epub 2018 Oct 10. Review.


Glibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 Polarization.

Kewcharoenwong C, Prabowo SA, Bancroft GJ, Fletcher HA, Lertmemongkolchai G.

Front Immunol. 2018 Sep 19;9:2109. doi: 10.3389/fimmu.2018.02109. eCollection 2018.


Screening for gestational diabetes mellitus: a Caribbean perspective.

Bassaw B, Fletcher H, Rattray C, McIntyre G, Sarkharkar V, Sankat S, Sirjusingh A, Chinnia J.

J Obstet Gynaecol. 2018 Nov;38(8):1035-1038. doi: 10.1080/01443615.2018.1467389. Epub 2018 Sep 26. Review.


Role of Acetyltransferase PG1842 in Gingipain Biogenesis in Porphyromonas gingivalis.

Mishra A, Roy F, Dou Y, Zhang K, Tang H, Fletcher HM.

J Bacteriol. 2018 Nov 26;200(24). pii: e00385-18. doi: 10.1128/JB.00385-18. Print 2018 Dec 15.


Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making.

Rhodes SJ, Guedj J, Fletcher HA, Lindenstrøm T, Scriba TJ, Evans TG, Knight GM, White RG.

NPJ Vaccines. 2018 Sep 17;3:36. doi: 10.1038/s41541-018-0075-3. eCollection 2018.


High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis.

Zelmer A, Stockdale L, Prabowo SA, Cia F, Spink N, Gibb M, Eddaoudi A, Fletcher HA.

Version 2. F1000Res. 2018 Mar 8 [revised 2018 Jan 1];7:296. doi: 10.12688/f1000research.14239.2. eCollection 2018.


VALIDATE: Exploiting the synergy between complex intracellular pathogens to expedite vaccine research and development for tuberculosis, leishmaniasis, melioidosis and leprosy.

Fletcher HA, Chatterjee M, Cooper A, Hussell T, Kaye PM, Prior J, Reljic R, Vermaak S, Vordermeier M, Williams A, McShane H.

F1000Res. 2018 Apr 23;7:485. doi: 10.12688/f1000research.14386.1. eCollection 2018.


Social determinants and BCG efficacy: a call for a socio-biological approach to TB prevention.

Dowd JB, Fletcher HA, Boccia D.

F1000Res. 2018 Feb 23;7:224. doi: 10.12688/f1000research.14085.1. eCollection 2018.


The convergent epidemiology of tuberculosis and human cytomegalovirus infection.

Cobelens F, Nagelkerke N, Fletcher H.

Version 2. F1000Res. 2018 Mar 6 [revised 2018 Jan 1];7:280. doi: 10.12688/f1000research.14184.2. eCollection 2018.


Progress and challenges in TB vaccine development.

Voss G, Casimiro D, Neyrolles O, Williams A, Kaufmann SHE, McShane H, Hatherill M, Fletcher HA.

F1000Res. 2018 Feb 16;7:199. doi: 10.12688/f1000research.13588.1. eCollection 2018. Review.


World TB Day 2018: The Challenge of Drug Resistant Tuberculosis.

Gupta-Wright A, Tomlinson GS, Rangaka MX, Fletcher HA.

F1000Res. 2018 Feb 22;7:217. doi: 10.12688/f1000research.14088.1. eCollection 2018.


Porphyromonas gingivalis: the gift of community involvement.

Fletcher HM.

Mol Oral Microbiol. 2018 Apr;33(2):111-112. doi: 10.1111/omi.12218. Epub 2018 Feb 20. No abstract available.


Human cytomegalovirus epidemiology and relationship to tuberculosis and cardiovascular disease risk factors in a rural Ugandan cohort.

Stockdale L, Nash S, Nalwoga A, Painter H, Asiki G, Fletcher H, Newton R.

PLoS One. 2018 Feb 6;13(2):e0192086. doi: 10.1371/journal.pone.0192086. eCollection 2018.


Role of extracytoplasmic function sigma factor PG1660 (RpoE) in the oxidative stress resistance regulatory network of Porphyromonas gingivalis.

Dou Y, Rutanhira H, Chen X, Mishra A, Wang C, Fletcher HM.

Mol Oral Microbiol. 2018 Feb;33(1):89-104. doi: 10.1111/omi.12204. Epub 2017 Dec 15.


Exercise-induced Fatigue in Severe Hypoxia after an Intermittent Hypoxic Protocol.

Twomey R, Wrightson J, Fletcher H, Avraam S, Ross E, Dekerle J.

Med Sci Sports Exerc. 2017 Dec;49(12):2422-2432. doi: 10.1249/MSS.0000000000001371.


The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.

Brennan MJ, Tanner R, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey DA, Izzo A, Sharpe S, Williams A, Penn-Nicholson A, Erasmus M, Stylianou E, Hoft DF, McShane H, Fletcher HA.

Clin Vaccine Immunol. 2017 Sep 5;24(9). pii: e00142-17. doi: 10.1128/CVI.00142-17. Print 2017 Sep. Review.


Clinical residual symptomatology and associated factors in multiple organ failure survivors: A long-term mortgage.

Rodríguez-Villar S, Rodríguez-García JL, Arévalo-Serrano J, Sánchez-Casado M, Fletcher H.

Rev Esp Anestesiol Reanim. 2017 Dec;64(10):550-559. doi: 10.1016/j.redar.2017.03.011. Epub 2017 May 23. English, Spanish.


A gaze independent hybrid-BCI based on visual spatial attention.

Egan JM, Loughnane GM, Fletcher H, Meade E, Lalor EC.

J Neural Eng. 2017 Aug;14(4):046006. doi: 10.1088/1741-2552/aa6bb2.


Factors associated with mercury levels in human placenta and the relationship to neonatal anthropometry in Jamaica and Trinidad & Tobago.

Ricketts P, Fletcher H, Voutchkov M.

Reprod Toxicol. 2017 Aug;71:78-83. doi: 10.1016/j.reprotox.2017.04.008. Epub 2017 Apr 28.


The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2017 Mar 3;7:43478. doi: 10.1038/srep43478. Erratum in: Sci Rep. 2019 Apr 3;9(1):5596.


Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study.

Andrews JR, Nemes E, Tameris M, Landry BS, Mahomed H, McClain JB, Fletcher HA, Hanekom WA, Wood R, McShane H, Scriba TJ, Hatherill M.

Lancet Respir Med. 2017 Apr;5(4):282-290. doi: 10.1016/S2213-2600(17)30060-7. Epub 2017 Feb 16.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods.

Rhodes SJ, Sarfas C, Knight GM, White A, Pathan AA, McShane H, Evans TG, Fletcher H, Sharpe S, White RG.

Clin Vaccine Immunol. 2017 Mar 6;24(3). pii: e00525-16. doi: 10.1128/CVI.00525-16. Print 2017 Mar.


The TB vaccine H56+IC31 dose-response curve is peaked not saturating: Data generation for new mathematical modelling methods to inform vaccine dose decisions.

Rhodes SJ, Zelmer A, Knight GM, Prabowo SA, Stockdale L, Evans TG, Lindenstrøm T, White RG, Fletcher H.

Vaccine. 2016 Dec 7;34(50):6285-6291. doi: 10.1016/j.vaccine.2016.10.060. Epub 2016 Nov 2.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


Polyfunctional CD4 T-cells correlate with in vitro mycobacterial growth inhibition following Mycobacterium bovis BCG-vaccination of infants.

Smith SG, Zelmer A, Blitz R, Fletcher HA, Dockrell HM.

Vaccine. 2016 Oct 17;34(44):5298-5305. doi: 10.1016/j.vaccine.2016.09.002. Epub 2016 Sep 9.


Assessment of fish consumption and mercury exposure among pregnant women in Jamaica and Trinidad & Tobago.

Ricketts P, Basu N, Fletcher H, Voutchkov M, Bassaw B.

Chemosphere. 2016 Dec;164:462-468. doi: 10.1016/j.chemosphere.2016.08.054. Epub 2016 Sep 7.


Sleeping Beauty and the Story of the Bacille Calmette-Guérin Vaccine.

Fletcher HA.

MBio. 2016 Aug 30;7(4). pii: e01370-16. doi: 10.1128/mBio.01370-16.


Investments in tuberculosis research - what are the gaps?

Khan MS, Fletcher H; London School of Hygiene and Tropical Medicine TB Centre Steering Committee, Coker R.

BMC Med. 2016 Aug 25;14(1):123. doi: 10.1186/s12916-016-0644-0.


In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy.

Tanner R, O'Shea MK, Fletcher HA, McShane H.

Vaccine. 2016 Sep 7;34(39):4656-4665. doi: 10.1016/j.vaccine.2016.07.058. Epub 2016 Aug 12. Review.


A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis.

Zelmer A, Tanner R, Stylianou E, Damelang T, Morris S, Izzo A, Williams A, Sharpe S, Pepponi I, Walker B, Hokey DA, McShane H, Brennan M, Fletcher H.

BMC Infect Dis. 2016 Aug 12;16:412. doi: 10.1186/s12879-016-1751-4.


Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points.

Vainieri ML, Blagborough AM, MacLean AL, Haltalli ML, Ruivo N, Fletcher HA, Stumpf MP, Sinden RE, Celso CL.

Open Biol. 2016 Jun;6(6). pii: 160038. doi: 10.1098/rsob.160038.


Human biomarkers: can they help us to develop a new tuberculosis vaccine?

Fletcher HA, Dockrell HM.

Future Microbiol. 2016 Jun;11:781-7. doi: 10.2217/fmb.16.15. Epub 2016 May 20. Review.


Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study.

Fletcher HA, Filali-Mouhim A, Nemes E, Hawkridge A, Keyser A, Njikan S, Hatherill M, Scriba TJ, Abel B, Kagina BM, Veldsman A, Agudelo NM, Kaplan G, Hussey GD, Sekaly RP, Hanekom WA; BCG study team.

BMC Med. 2016 May 16;14:76. doi: 10.1186/s12916-016-0617-3.


Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants.

Fletcher HA, Snowden MA, Landry B, Rida W, Satti I, Harris SA, Matsumiya M, Tanner R, O'Shea MK, Dheenadhayalan V, Bogardus L, Stockdale L, Marsay L, Chomka A, Harrington-Kandt R, Manjaly-Thomas ZR, Naranbhai V, Stylianou E, Darboe F, Penn-Nicholson A, Nemes E, Hatherill M, Hussey G, Mahomed H, Tameris M, McClain JB, Evans TG, Hanekom WA, Scriba TJ, McShane H.

Nat Commun. 2016 May 6;7:11633. doi: 10.1038/ncomms11633. No abstract available.

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