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Items: 1 to 50 of 70

1.

Limitations of resting haemodynamics in chronic thromboembolic disease without pulmonary hypertension.

Swietlik EM, Ruggiero A, Fletcher AJ, Taboada D, Knightbridge E, Harlow L, Harvey I, Screaton N, Cannon JE, Sheares KKK, Ng C, Jenkins DP, Pepke-Zaba J, Toshner MR.

Eur Respir J. 2018 Nov 8. pii: 1801787. doi: 10.1183/13993003.01787-2018. [Epub ahead of print] No abstract available.

PMID:
30409818
2.

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.

Dickson C, Fletcher AJ, Vaysburd M, Yang JC, Mallery DL, Zeng J, Johnson CM, McLaughlin SH, Skehel M, Maslen S, Cruickshank J, Huguenin-Dezot N, Chin JW, Neuhaus D, James LC.

Elife. 2018 Apr 18;7. pii: e32660. doi: 10.7554/eLife.32660.

3.

Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases.

Hudson AM, Stephenson NL, Li C, Trotter E, Fletcher AJ, Katona G, Bieniasz-Krzywiec P, Howell M, Wirth C, Furney S, Miller CJ, Brognard J.

Sci Signal. 2018 Apr 17;11(526). pii: eaan6776. doi: 10.1126/scisignal.aan6776.

PMID:
29666306
4.

Solvent-switchable continuous-breathing behaviour in a diamondoid metal-organic framework and its influence on CO2 versus CH4 selectivity.

Carrington EJ, McAnally CA, Fletcher AJ, Thompson SP, Warren M, Brammer L.

Nat Chem. 2017 Sep;9(9):882-889. doi: 10.1038/nchem.2747. Epub 2017 Mar 14.

5.

Coordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21.

Fletcher AJ, James LC.

J Virol. 2016 Apr 29;90(10):4856-4859. doi: 10.1128/JVI.00050-16. Print 2016 May 15. Review.

6.

Prioritizing health leadership capabilities in Canada: Testing LEADS in a Caring Environment.

Marchildon GP, Fletcher AJ.

Healthc Manage Forum. 2016 Jan;29(1):19-22. doi: 10.1177/0840470415602744. Epub 2015 Dec 9. Review.

PMID:
26656384
7.

Effects of Secondary Metal Carbonate Addition on the Porous Character of Resorcinol-Formaldehyde Xerogels.

Taylor SJ, Haw MD, Sefcik J, Fletcher AJ.

Langmuir. 2015 Dec 22;31(50):13571-80. doi: 10.1021/acs.langmuir.5b02483. Epub 2015 Dec 11.

PMID:
26630450
8.

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21.

Fletcher AJ, Mallery DL, Watkinson RE, Dickson CF, James LC.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):10014-9. doi: 10.1073/pnas.1507534112. Epub 2015 Jul 6.

9.

TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.

Fletcher AJ, Christensen DE, Nelson C, Tan CP, Schaller T, Lehner PJ, Sundquist WI, Towers GJ.

EMBO J. 2015 Aug 4;34(15):2078-95. doi: 10.15252/embj.201490361. Epub 2015 Jun 22.

10.

Coordination polymer flexibility leads to polymorphism and enables a crystalline solid-vapour reaction: a multi-technique mechanistic study.

Vitórica-Yrezábal IJ, Libri S, Loader JR, Mínguez Espallargas G, Hippler M, Fletcher AJ, Thompson SP, Warren JE, Musumeci D, Ward MD, Brammer L.

Chemistry. 2015 Jun 8;21(24):8799-811. doi: 10.1002/chem.201500514. Epub 2015 May 11.

11.

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

Price AJ, Jacques DA, McEwan WA, Fletcher AJ, Essig S, Chin JW, Halambage UD, Aiken C, James LC.

PLoS Pathog. 2014 Oct 30;10(10):e1004459. doi: 10.1371/journal.ppat.1004459. eCollection 2014 Oct.

12.

Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation.

Guiliano DB, Fussell H, Lenart I, Tsao E, Nesbeth D, Fletcher AJ, Campbell EC, Yousaf N, Williams S, Santos S, Cameron A, Towers GJ, Kellam P, Hebert DN, Gould KG, Powis SJ, Antoniou AN.

Arthritis Rheumatol. 2014 Nov;66(11):2976-88. doi: 10.1002/art.38809.

13.

Gelation mechanism of resorcinol-formaldehyde gels investigated by dynamic light scattering.

Taylor SJ, Haw MD, Sefcik J, Fletcher AJ.

Langmuir. 2014 Sep 2;30(34):10231-40. doi: 10.1021/la502394u. Epub 2014 Aug 21.

PMID:
25100498
14.

Perceptions regarding genetic testing in populations at risk for nephropathy.

Freedman BI, Fletcher AJ, Sanghani VR, Spainhour M, Graham AW, Russell GB, Cooke Bailey JN, Iltis AS, King NM.

Am J Nephrol. 2013;38(6):453-7. doi: 10.1159/000356244. Epub 2013 Nov 21.

15.

HIV-1 evades innate immune recognition through specific cofactor recruitment.

Rasaiyaah J, Tan CP, Fletcher AJ, Price AJ, Blondeau C, Hilditch L, Jacques DA, Selwood DL, James LC, Noursadeghi M, Towers GJ.

Nature. 2013 Nov 21;503(7476):402-405. doi: 10.1038/nature12769. Epub 2013 Nov 6.

16.

Ethnicity, medical insurance, and living kidney donation.

Reeves-Daniel AM, Farney AC, Fletcher AJ, Assimos D, Westcott C, Rogers J, Stratta RJ, Rocco MV, Freedman BI.

Clin Transplant. 2013 Jul-Aug;27(4):E498-503. doi: 10.1111/ctr.12168. Epub 2013 Jun 19.

PMID:
23781870
17.

Inhibition of retroviral replication by members of the TRIM protein family.

Fletcher AJ, Towers GJ.

Curr Top Microbiol Immunol. 2013;371:29-66. doi: 10.1007/978-3-642-37765-5_2. Review.

PMID:
23686231
18.

Zipping and unzipping of a paddlewheel metal-organic framework to enable two-step synthetic and structural transformation.

Smart P, Mason CA, Loader JR, Meijer AJ, Florence AJ, Shankland K, Fletcher AJ, Thompson SP, Brunelli M, Hill AH, Brammer L.

Chemistry. 2013 Mar 11;19(11):3552-7. doi: 10.1002/chem.201204492. Epub 2013 Feb 11. No abstract available.

PMID:
23401016
19.

Metaldehyde removal from aqueous solution by adsorption and ion exchange mechanisms onto activated carbon and polymeric sorbents.

Tao B, Fletcher AJ.

J Hazard Mater. 2013 Jan 15;244-245:240-50. doi: 10.1016/j.jhazmat.2012.11.014. Epub 2012 Nov 20.

PMID:
23257324
20.

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.

Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC.

PLoS Pathog. 2012;8(8):e1002896. doi: 10.1371/journal.ppat.1002896. Epub 2012 Aug 30.

21.

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, KewalRamani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ.

PLoS Pathog. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.ppat.1002439. Epub 2011 Dec 8.

22.

Sex differences in the ovine fetal cortisol response to stress.

Giussani DA, Fletcher AJ, Gardner DS.

Pediatr Res. 2011 Feb;69(2):118-22. doi: 10.1203/PDR.0b013e3182042a20.

PMID:
21045750
23.

Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes.

Fletcher AJ, Hué S, Schaller T, Pillay D, Towers GJ.

J Virol. 2010 Dec;84(23):12463-8. doi: 10.1128/JVI.01514-10. Epub 2010 Sep 22.

24.

Enantioselective desymmetrizing palladium catalyzed carbonylation reactions: the catalytic asymmetric synthesis of quaternary carbon center containing 1,3-dienes.

Byrne SJ, Fletcher AJ, Hebeisen P, Willis MC.

Org Biomol Chem. 2010 Feb 21;8(4):758-60. doi: 10.1039/b923186b. Epub 2009 Dec 21.

PMID:
20135030
25.

Chemically blockable transformation and ultraselective low-pressure gas adsorption in a non-porous metal organic framework.

Xiao B, Byrne PJ, Wheatley PS, Wragg DS, Zhao X, Fletcher AJ, Thomas KM, Peters L, Evans JS, Warren JE, Zhou W, Morris RE.

Nat Chem. 2009 Jul;1(4):289-94.

PMID:
21495253
26.

Levomepromazine-induced lupus?

Fletcher AJ.

J Pain Symptom Manage. 2009 Jun;37(6):e1-2. doi: 10.1016/j.jpainsymman.2008.12.001. No abstract available.

PMID:
19500717
27.

Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D.

Ylinen LM, Schaller T, Price A, Fletcher AJ, Noursadeghi M, James LC, Towers GJ.

J Virol. 2009 Feb;83(4):2044-7. doi: 10.1128/JVI.01876-08. Epub 2008 Dec 10.

28.

The LoTrach system: its role in the prevention of ventilator-associated pneumonia.

Fletcher AJ, Ruffell AJ, Young PJ.

Nurs Crit Care. 2008 Sep-Oct;13(5):260-8. doi: 10.1111/j.1478-5153.2008.00286.x. Review.

PMID:
18816312
29.

Quality data and documentation for EHRs in physician practice.

Cuvo JB, Dinh AK, Fahrenholz CG, Fletcher AJ, Howrey LM, Levinson SR, Washington L.

J AHIMA. 2008 Aug;79(8):43-8. No abstract available.

PMID:
18720680
30.

Surface interactions and quantum kinetic molecular sieving for H2 and D2 adsorption on a mixed metal-organic framework material.

Chen B, Zhao X, Putkham A, Hong K, Lobkovsky EB, Hurtado EJ, Fletcher AJ, Thomas KM.

J Am Chem Soc. 2008 May 21;130(20):6411-23. doi: 10.1021/ja710144k. Epub 2008 Apr 25.

PMID:
18435535
31.

A novel method to treat hyperthermia in a burns case: use of a catheter-based heat exchange system.

Mavrogordato AE, Wagstaff MJ, Fletcher AJ, Wilson DI, Jayamaha JE.

Burns. 2009 Feb;35(1):141-5. doi: 10.1016/j.burns.2007.10.014. Epub 2008 Apr 18. No abstract available.

PMID:
18378401
32.
33.

Nitric oxide-mediated nonadrenergic noncholinergic relaxation of piglet pulmonary arteries decreases with postnatal age.

Gonzáles-Luis G, Fletcher AJ, Moreno L, Pérez-Vizcaíno F, Blanco CE, Villamor E.

J Physiol Pharmacol. 2007 Mar;58(1):45-56.

34.

High-capacity hydrogen and nitric oxide adsorption and storage in a metal-organic framework.

Xiao B, Wheatley PS, Zhao X, Fletcher AJ, Fox S, Rossi AG, Megson IL, Bordiga S, Regli L, Thomas KM, Morris RE.

J Am Chem Soc. 2007 Feb 7;129(5):1203-9.

PMID:
17263402
35.
36.

Development of the ovine fetal cardiovascular defense to hypoxemia towards full term.

Fletcher AJ, Gardner DS, Edwards CM, Fowden AL, Giussani DA.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H3023-34. Epub 2006 Jul 21.

37.

Hydrogen adsorption on functionalized nanoporous activated carbons.

Zhao XB, Xiao B, Fletcher AJ, Thomas KM.

J Phys Chem B. 2005 May 12;109(18):8880-8.

PMID:
16852056
38.

Kinetic isotope effect for H2 and D2 quantum molecular sieving in adsorption/desorption on porous carbon materials.

Zhao X, Villar-Rodil S, Fletcher AJ, Thomas KM.

J Phys Chem B. 2006 May 25;110(20):9947-55.

PMID:
16706452
39.

Assembly of heterometallic clusters and coordination polymers by combining Mo-S-based clusters with Mn2+.

Lin P, Clegg W, Harrington RW, Henderson RA, Fletcher AJ, Bell J, Thomas KM.

Inorg Chem. 2006 May 15;45(10):4284-302.

PMID:
16676992
40.

Synthesis of ellipticine: a radical cascade protocol to aryl- and heteroaryl-annulated[b]carbazoles.

Pedersen JM, Bowman WR, Elsegood MR, Fletcher AJ, Lovell PJ.

J Org Chem. 2005 Dec 9;70(25):10615-8.

PMID:
16323886
41.

Synthesis of heteroarenes using cascade radical cyclisation via iminyl radicals.

Bowman WR, Cloonan MO, Fletcher AJ, Stein T.

Org Biomol Chem. 2005 Apr 21;3(8):1460-7. Epub 2005 Mar 10.

PMID:
15827642
42.

Effects of gestational age and cortisol treatment on ovine fetal heart function in a novel biventricular Langendorff preparation.

Fletcher AJ, Forhead AJ, Fowden AL, Ford WR, Nathanielsz PW, Giussani DA.

J Physiol. 2005 Jan 15;562(Pt 2):493-505. Epub 2004 Oct 28.

43.

Hysteretic adsorption and desorption of hydrogen by nanoporous metal-organic frameworks.

Zhao X, Xiao B, Fletcher AJ, Thomas KM, Bradshaw D, Rosseinsky MJ.

Science. 2004 Nov 5;306(5698):1012-5. Epub 2004 Oct 14.

44.
45.

The pupillary effects of intravenous morphine, codeine, and tramadol in volunteers.

Knaggs RD, Crighton IM, Cobby TF, Fletcher AJ, Hobbs GJ.

Anesth Analg. 2004 Jul;99(1):108-12.

PMID:
15281513
46.

Adrenocortical responsiveness is blunted in twin relative to singleton ovine fetuses.

Gardner DS, Jamall E, Fletcher AJ, Fowden AL, Giussani DA.

J Physiol. 2004 Jun 15;557(Pt 3):1021-32. Epub 2004 Apr 8.

47.

Antenatal glucocorticoids reset the level of baseline and hypoxemia-induced pituitary-adrenal activity in the sheep fetus during late gestation.

Fletcher AJ, Ma XH, Wu WX, Nathanielsz PW, McGarrigle HH, Fowden AL, Giussani DA.

Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E311-9. Epub 2003 Oct 14.

48.

Cardiovascular and endocrine responses to acute hypoxaemia during and following dexamethasone infusion in the ovine fetus.

Fletcher AJ, Gardner DS, Edwards CM, Fowden AL, Giussani DA.

J Physiol. 2003 May 15;549(Pt 1):271-87. Epub 2003 Mar 28.

49.

The role of neuropeptide Y in the ovine fetal cardiovascular response to reduced oxygenation.

Sanhueza EM, Johansen-Bibby AA, Fletcher AJ, Riquelme RA, Daniels AJ, Serón-Ferré M, Gaete CR, Carrasco JE, Llanos AJ, Giussani DA.

J Physiol. 2003 Feb 1;546(Pt 3):891-901.

50.

Enhanced nitric oxide activity offsets peripheral vasoconstriction during acute hypoxaemia via chemoreflex and adrenomedullary actions in the sheep fetus.

Morrison S, Gardner DS, Fletcher AJ, Bloomfield MR, Giussani DA.

J Physiol. 2003 Feb 15;547(Pt 1):283-91. Epub 2003 Jan 10.

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