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Items: 1 to 50 of 955

1.

A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.

Li JY, Perry SR, Muniz-Medina V, Wang X, Wetzel LK, Rebelatto MC, Masson Hinrichs MJ, Bezabeh BZ, Fleming RL, Dimasi N, Feng H, Toader D, Yuan AQ, Xu L, Lin J, Gao C, Wu H, Dixit R, Osbourn JK, Coats SR.

Cancer Cell. 2019 Jun 10;35(6):948-949. doi: 10.1016/j.ccell.2019.05.010. No abstract available.

PMID:
31185215
2.

Outcomes associated with a change in clinical practice to alleviate emotional harm related to venous thromboembolism.

Jones AE, Feehan M, Fleming R, Johnson SA, Witt DM.

Thromb Res. 2019 Jun 1;180:29-31. doi: 10.1016/j.thromres.2019.05.022. [Epub ahead of print] No abstract available.

PMID:
31176947
3.

Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease.

Heinken A, Ravcheev DA, Baldini F, Heirendt L, Fleming RMT, Thiele I.

Microbiome. 2019 May 15;7(1):75. doi: 10.1186/s40168-019-0689-3.

4.

Developmental validation of an enhanced mRNA-based multiplex system for body fluid and cell type identification.

Albani PP, Fleming R.

Sci Justice. 2019 May;59(3):217-227. doi: 10.1016/j.scijus.2019.01.001. Epub 2019 Jan 22. No abstract available.

PMID:
31054812
5.

Metabolic and signalling network maps integration: application to cross-talk studies and omics data analysis in cancer.

Sompairac N, Modamio J, Barillot E, Fleming RMT, Zinovyev A, Kuperstein I.

BMC Bioinformatics. 2019 Apr 18;20(Suppl 4):140. doi: 10.1186/s12859-019-2682-z.

6.

Integration of prior knowledge during haptic exploration depends on information type.

Zoeller AC, Lezkan A, Paulun VC, Fleming RW, Drewing K.

J Vis. 2019 Apr 1;19(4):20. doi: 10.1167/19.4.20.

PMID:
30998830
7.

A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours.

Mak G, Soria JC, Blagden SP, Plummer R, Fleming RA, Nebot N, Zhang J, Mazumdar J, Rogan D, Gazzah A, Rizzuto I, Greystoke A, Yan L, Tolson J, Auger KR, Arkenau HT.

Br J Cancer. 2019 May;120(10):975-981. doi: 10.1038/s41416-019-0452-3. Epub 2019 Apr 17.

PMID:
30992546
8.

Visual perception of shape-transforming processes: 'Shape Scission'.

Schmidt F, Phillips F, Fleming RW.

Cognition. 2019 Aug;189:167-180. doi: 10.1016/j.cognition.2019.04.006. Epub 2019 Apr 12.

PMID:
30986590
9.

Characterization of Disulfide Bond Rebridged Fab-Drug Conjugates Prepared Using a Dual Maleimide Pyrrolobenzodiazepine Cytotoxic Payload.

Ruddle BT, Fleming R, Wu H, Gao C, Dimasi N.

ChemMedChem. 2019 Apr 13. doi: 10.1002/cmdc.201900077. [Epub ahead of print]

PMID:
30980702
10.

Relation of Patent Foramen Ovale to Acute Mountain Sickness.

West BH, Fleming RG, Al Hemyari B, Banankhah P, Meyer K, Rozier LH, Murphy LS, Coluzzi AC, Rusheen JL, Kumar P, Elashoff D, Tobis JM.

Am J Cardiol. 2019 Jun 15;123(12):2022-2025. doi: 10.1016/j.amjcard.2019.03.030. Epub 2019 Mar 18.

PMID:
30979412
11.

Getting "fumpered": Classifying objects by what has been done to them.

Fleming RW, Schmidt F.

J Vis. 2019 Apr 1;19(4):15. doi: 10.1167/19.4.15.

PMID:
30952166
12.

General anesthetic exposure in adolescent rats causes persistent maladaptations in cognitive and affective behaviors and neuroplasticity.

Landin JD, Palac M, Carter JM, Dzumaga Y, Santerre-Anderson JL, Fernandez GM, Savage LM, Varlinskaya EI, Spear LP, Moore SD, Swartzwelder HS, Fleming RL, Werner DF.

Neuropharmacology. 2019 May 15;150:153-163. doi: 10.1016/j.neuropharm.2019.03.022. Epub 2019 Mar 26.

PMID:
30926450
13.

Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer.

White JB, Fleming R, Masterson L, Ruddle BT, Zhong H, Fazenbaker C, Strout P, Rosenthal K, Reed M, Muniz-Medina V, Howard P, Dixit R, Wu H, Hinrichs MJ, Gao C, Dimasi N.

MAbs. 2019 Apr;11(3):500-515. doi: 10.1080/19420862.2019.1578611. Epub 2019 Mar 5.

PMID:
30835621
14.

Object Visibility, Not Energy Expenditure, Accounts For Spatial Biases in Human Grasp Selection.

Maiello G, Paulun VC, Klein LK, Fleming RW.

Iperception. 2019 Feb 24;10(1):2041669519827608. doi: 10.1177/2041669519827608. eCollection 2019 Jan-Feb.

15.

Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.

Heirendt L, Arreckx S, Pfau T, Mendoza SN, Richelle A, Heinken A, Haraldsdóttir HS, Wachowiak J, Keating SM, Vlasov V, Magnusdóttir S, Ng CY, Preciat G, Žagare A, Chan SHJ, Aurich MK, Clancy CM, Modamio J, Sauls JT, Noronha A, Bordbar A, Cousins B, El Assal DC, Valcarcel LV, Apaolaza I, Ghaderi S, Ahookhosh M, Ben Guebila M, Kostromins A, Sompairac N, Le HM, Ma D, Sun Y, Wang L, Yurkovich JT, Oliveira MAP, Vuong PT, El Assal LP, Kuperstein I, Zinovyev A, Hinton HS, Bryant WA, Aragón Artacho FJ, Planes FJ, Stalidzans E, Maass A, Vempala S, Hucka M, Saunders MA, Maranas CD, Lewis NE, Sauter T, Palsson BØ, Thiele I, Fleming RMT.

Nat Protoc. 2019 Mar;14(3):639-702. doi: 10.1038/s41596-018-0098-2.

PMID:
30787451
16.

Umbilical Cord Serum Ferritin Concentration is Inversely Associated with Umbilical Cord Hemoglobin in Neonates Born to Adolescents Carrying Singletons and Women Carrying Multiples.

Delaney KM, Guillet R, Fleming RE, Ru Y, Pressman EK, Vermeylen F, Nemeth E, O'Brien KO.

J Nutr. 2019 Mar 1;149(3):406-415. doi: 10.1093/jn/nxy286.

PMID:
30770543
17.

Automated microfluidic cell culture of stem cell derived dopaminergic neurons.

Kane KIW, Moreno EL, Hachi S, Walter M, Jarazo J, Oliveira MAP, Hankemeier T, Vulto P, Schwamborn JC, Thoma M, Fleming RMT.

Sci Rep. 2019 Feb 11;9(1):1796. doi: 10.1038/s41598-018-34828-3.

18.

Impact of unilateral versus bilateral ovarian endometriotic cystectomy on ovarian reserve: a systematic review and meta-analysis.

Younis JS, Shapso N, Fleming R, Ben-Shlomo I, Izhaki I.

Hum Reprod Update. 2019 May 1;25(3):375-391. doi: 10.1093/humupd/dmy049.

PMID:
30715359
19.

Letter to the Editor: A response to Hruska's case study on molecular breast imaging and the need for true tissue quantification.

Fleming RM, Fleming MR, Chaudhuri TK, Dooley WC, McKusick A.

Breast Cancer Res. 2019 Jan 29;21(1):15. doi: 10.1186/s13058-019-1103-6. No abstract available.

20.

The material-weight illusion disappears or inverts in objects made of two materials.

Paulun VC, Buckingham G, Goodale MA, Fleming RW.

J Neurophysiol. 2019 Mar 1;121(3):996-1010. doi: 10.1152/jn.00199.2018. Epub 2019 Jan 23.

21.

Male Intimate Partner Violence Perpetrators' Perceptions of the Positives and Negatives of Peer Interactions in Group Batterer Intervention Programs.

Morrison PK, George D, Cluss PA, Miller E, Hawker L, Fleming R, Bicehouse T, Burke J, Chang JC.

Violence Against Women. 2019 Jan 22:1077801218824053. doi: 10.1177/1077801218824053. [Epub ahead of print]

PMID:
30666903
22.

3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing.

Bolognin S, Fossépré M, Qing X, Jarazo J, Ščančar J, Moreno EL, Nickels SL, Wasner K, Ouzren N, Walter J, Grünewald A, Glaab E, Salamanca L, Fleming RMT, Antony PMA, Schwamborn JC.

Adv Sci (Weinh). 2018 Nov 20;6(1):1800927. doi: 10.1002/advs.201800927. eCollection 2019 Jan 9.

23.

Tfr2 suppression benefits β-thalassemic erythropoiesis.

Ginzburg YZ, Fleming RE.

Blood. 2018 Nov 22;132(21):2215-2216. doi: 10.1182/blood-2018-10-876110. No abstract available.

24.

The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities.

Baldini F, Heinken A, Heirendt L, Magnusdottir S, Fleming RMT, Thiele I.

Bioinformatics. 2018 Nov 21. doi: 10.1093/bioinformatics/bty941. [Epub ahead of print]

PMID:
30462168
25.

DNA on feminine sanitary products.

Albani PP, Patel J, Fleming RI.

Forensic Sci Int. 2018 Dec;293:24-26. doi: 10.1016/j.forsciint.2018.10.010. Epub 2018 Oct 21.

PMID:
30396148
26.

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips.

Novak R, Didier M, Calamari E, Ng CF, Choe Y, Clauson SL, Nestor BA, Puerta J, Fleming R, Firoozinezhad SJ, Ingber DE.

J Vis Exp. 2018 Oct 20;(140). doi: 10.3791/58151. Erratum in: J Vis Exp. 2019 May 8;(147):.

PMID:
30394380
27.

The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease.

Noronha A, Modamio J, Jarosz Y, Guerard E, Sompairac N, Preciat G, Daníelsdóttir AD, Krecke M, Merten D, Haraldsdóttir HS, Heinken A, Heirendt L, Magnúsdóttir S, Ravcheev DA, Sahoo S, Gawron P, Friscioni L, Garcia B, Prendergast M, Puente A, Rodrigues M, Roy A, Rouquaya M, Wiltgen L, Žagare A, John E, Krueger M, Kuperstein I, Zinovyev A, Schneider R, Fleming RMT, Thiele I.

Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.

28.

Re-design of Aged Care Environments is Key to Improved Care Quality and Cost Effective Reform of Aged and Health System Care.

Eckermann S, Phillipson L, Fleming R.

Appl Health Econ Health Policy. 2019 Apr;17(2):127-130. doi: 10.1007/s40258-018-0435-1. No abstract available.

PMID:
30328015
29.

Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells.

Kinneer K, Flynn M, Thomas SB, Meekin J, Varkey R, Xiao X, Zhong H, Breen S, Hynes PG, Fleming R, Bezabeh B, Chen CT, Wetzel L, Chen R, Dimasi N, Tai YT, Anderson KC, Herbst R, Howard PW, Hurt EM, Tice DA.

Leukemia. 2019 Mar;33(3):766-771. doi: 10.1038/s41375-018-0278-7. Epub 2018 Oct 12. No abstract available.

PMID:
30315237
30.

Olfactory Ensheathing Cells: A Trojan Horse for Glioma Gene Therapy.

Carvalho LA, Teng J, Fleming RL, Tabet EI, Zinter M, de Melo Reis RA, Tannous BA.

J Natl Cancer Inst. 2019 Mar 1;111(3):283-291. doi: 10.1093/jnci/djy138.

PMID:
30257000
31.

Identifying shape transformations from photographs of real objects.

Schmidt F, Fleming RW.

PLoS One. 2018 Aug 16;13(8):e0202115. doi: 10.1371/journal.pone.0202115. eCollection 2018.

32.

Molecular engineering strategies and methods for the expression and purification of IgG1-based bispecific bivalent antibodies.

Dimasi N, Fleming R, Wu H, Gao C.

Methods. 2019 Feb 1;154:77-86. doi: 10.1016/j.ymeth.2018.08.004. Epub 2018 Aug 11. Review.

PMID:
30102989
33.

The Sequential-Weight Illusion.

Maiello G, Paulun VC, Klein LK, Fleming RW.

Iperception. 2018 Jul 25;9(4):2041669518790275. doi: 10.1177/2041669518790275. eCollection 2018 Jul-Aug.

34.

Reply to "Challenges in modeling the human gut microbiome".

Magnúsdóttir S, Heinken A, Fleming RMT, Thiele I.

Nat Biotechnol. 2018 Aug 6;36(8):686-691. doi: 10.1038/nbt.4212. No abstract available.

PMID:
30080835
35.

Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.

Cho S, Zammarchi F, Williams DG, Havenith CEG, Monks NR, Tyrer P, D'Hooge F, Fleming R, Vashisht K, Dimasi N, Bertelli F, Corbett S, Adams L, Reinert HW, Dissanayake S, Britten CE, King W, Dacosta K, Tammali R, Schifferli K, Strout P, Korade M 3rd, Masson Hinrichs MJ, Chivers S, Corey E, Liu H, Kim S, Bander NH, Howard PW, Hartley JA, Coats S, Tice DA, Herbst R, van Berkel PH.

Mol Cancer Ther. 2018 Oct;17(10):2176-2186. doi: 10.1158/1535-7163.MCT-17-0982. Epub 2018 Jul 31.

PMID:
30065100
36.

Semiquantification Limitations: FMTVDM©℗ Demonstrates Quantified Tumor Response to Treatment with Both Regional Blood Flow and Metabolic Changes.

Fleming RM, Fleming MR, McKusick A, Chaudhuri TK.

J Nucl Med. 2018 Oct;59(10):1643-1644. doi: 10.2967/jnumed.118.217018. Epub 2018 Jul 20. No abstract available.

PMID:
30030345
37.

Colour, contours, shading and shape: flow interactions reveal anchor neighbourhoods.

Kunsberg B, Holtmann-Rice D, Alexander E, Cholewiak S, Fleming R, Zucker SW.

Interface Focus. 2018 Aug 6;8(4):20180019. doi: 10.1098/rsfs.2018.0019. Epub 2018 Jun 15.

PMID:
29951196
38.

FMTVDM-TFM©℗: True quantification requires standardization of the tool being used to measure, with a known, unchanging standard to produce accurate, consistent and reproducible quantified measurements.

Fleming RM, Fleming MR, McKusick A, Chaudhuri T.

J Nucl Cardiol. 2018 Jun 19. doi: 10.1007/s12350-018-1343-3. [Epub ahead of print] No abstract available.

PMID:
29923099
39.

The Challenges of Working With Men Who Perpetrate Partner Violence: Perspectives and Observations of Experts Who Work With Batterer Intervention Programs.

Morrison PK, Hawker L, Cluss PA, Miller E, Fleming R, Bicehouse T, George D, Burke J, Wright K, Chang JC.

J Interpers Violence. 2018 Jun 1:886260518778258. doi: 10.1177/0886260518778258. [Epub ahead of print]

PMID:
29897001
40.

Effectiveness of environment assessment tools to guide refurbishment of Australian residential aged care facilities: A systematic review.

Fleming R.

Australas J Ageing. 2018 Jun;37(2):88-89. doi: 10.1111/ajag.12441. No abstract available.

PMID:
29870148
41.

Prevalence and correlates of bleeding and emotional harms in a national US sample of patients with venous thromboembolism: A cross-sectional structural equation model.

Feehan M, Walsh M, Van Duker H, Godin J, Munger MA, Fleming R, Johnson SA, Morrison MA, DeAngelis MM, Witt DM.

Thromb Res. 2018 Dec;172:181-187. doi: 10.1016/j.thromres.2018.05.025. Epub 2018 May 23.

PMID:
29843918
42.

A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [11C]GSK2256098.

Brown NF, Williams M, Arkenau HT, Fleming RA, Tolson J, Yan L, Zhang J, Swartz L, Singh R, Auger KR, Lenox L, Cox D, Lewis Y, Plisson C, Searle G, Saleem A, Blagden S, Mulholland P.

Neuro Oncol. 2018 Nov 12;20(12):1634-1642. doi: 10.1093/neuonc/noy078.

PMID:
29788497
43.

Genome-wide association study for bone strength in laying hens.

Raymond B, Johansson AM, McCormack HA, Fleming RH, Schmutz M, Dunn IC, De Koning DJ.

J Anim Sci. 2018 Jun 29;96(7):2525-2535. doi: 10.1093/jas/sky157.

PMID:
29701819
44.

Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia.

Carvalho LA, Fleming R, Sant'Anna M, Guimarães R, Dantas AM, Morizot-Leite E, Cavalcante LA, Allodi S.

Clinics (Sao Paulo). 2018;73:e161. doi: 10.6061/clinics/2018/e161. Epub 2018 Apr 19.

45.

Community-driven roadmap for integrated disease maps.

Ostaszewski M, Gebel S, Kuperstein I, Mazein A, Zinovyev A, Dogrusoz U, Hasenauer J, Fleming RMT, Le Novère N, Gawron P, Ligon T, Niarakis A, Nickerson D, Weindl D, Balling R, Barillot E, Auffray C, Schneider R.

Brief Bioinform. 2019 Mar 25;20(2):659-670. doi: 10.1093/bib/bby024.

46.

NIH/Kennedy Center Workshop on Music and the Brain: Finding Harmony.

Cheever T, Taylor A, Finkelstein R, Edwards E, Thomas L, Bradt J, Holochwost SJ, Johnson JK, Limb C, Patel AD, Tottenham N, Iyengar S, Rutter D, Fleming R, Collins FS.

Neuron. 2018 Mar 21;97(6):1214-1218. doi: 10.1016/j.neuron.2018.02.004.

47.

Novel messenger RNAs for body fluid identification.

Albani PP, Fleming R.

Sci Justice. 2018 Mar;58(2):145-152. doi: 10.1016/j.scijus.2017.09.002. Epub 2017 Sep 25.

PMID:
29526266
48.

Recon3D enables a three-dimensional view of gene variation in human metabolism.

Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Dräger A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlić A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, Rose PW, Burley SK, Fleming RMT, Nielsen J, Thiele I, Palsson BO.

Nat Biotechnol. 2018 Mar;36(3):272-281. doi: 10.1038/nbt.4072. Epub 2018 Feb 19.

49.

Visual Features in the Perception of Liquids.

van Assen JJR, Barla P, Fleming RW.

Curr Biol. 2018 Feb 5;28(3):452-458.e4. doi: 10.1016/j.cub.2017.12.037. Epub 2018 Jan 27.

50.

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry.

Parrow NL, Violet PC, Tu H, Nichols J, Pittman CA, Fitzhugh C, Fleming RE, Mohandas N, Tisdale JF, Levine M.

J Vis Exp. 2018 Jan 12;(131). doi: 10.3791/56910.

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