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Items: 1 to 50 of 524

1.

Relative Tissue Oxygenation and Temperature Changes for Detecting Early Upper Extremity Skin Ischemia.

Polfer EM, Sabino JM, Fleming IC, Means KR Jr.

Plast Reconstr Surg. 2019 Oct;144(4):907-910. doi: 10.1097/PRS.0000000000006024.

PMID:
31568302
2.

Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction.

Lasch M, Kleinert EC, Meister S, Kumaraswami K, Buchheim JI, Grantzow T, Lautz T, Salpisti S, Fischer S, Troidl K, Fleming I, Randi AM, Sperandio M, Preissner KT, Deindl E.

Blood. 2019 Sep 9. pii: blood.2019001392. doi: 10.1182/blood.2019001392. [Epub ahead of print]

PMID:
31501155
3.

Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity.

Hu J, Bibli SI, Wittig J, Zukunft S, Lin J, Hammes HP, Popp R, Fleming I.

J Clin Invest. 2019 Sep 3. pii: 123835. doi: 10.1172/JCI123835. [Epub ahead of print]

4.

New Lipid Mediators in Retinal Angiogenesis and Retinopathy.

Fleming I.

Front Pharmacol. 2019 Jul 5;10:739. doi: 10.3389/fphar.2019.00739. eCollection 2019. Review.

5.

Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.

Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I.

EMBO J. 2019 Sep 2;38(17):e100938. doi: 10.15252/embj.2018100938. Epub 2019 Jul 22.

PMID:
31328803
6.

Relative Tissue Oxygenation and Temperature Changes for Detecting Early Upper Extremity Skin Ischemia.

Polfer EM, Sabino JM, Fleming IC, Means KR Jr.

Plast Reconstr Surg. 2019 Jun 27. doi: 10.1097/PRS.0000000000006024. [Epub ahead of print]

PMID:
31261263
7.

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.

8.

Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS.

Leisegang MS, Bibli SI, Günther S, Pflüger-Müller B, Oo JA, Höper C, Seredinski S, Yekelchyk M, Schmitz-Rixen T, Schürmann C, Hu J, Looso M, Sigala F, Boon RA, Fleming I, Brandes RP.

Eur Heart J. 2019 Aug 7;40(30):2523-2533. doi: 10.1093/eurheartj/ehz393.

PMID:
31222221
9.

Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.

Iring A, Jin YJ, Albarrán-Juárez J, Siragusa M, Wang S, Dancs PT, Nakayama A, Tonack S, Chen M, Künne C, Sokol AM, Günther S, Martínez A, Fleming I, Wettschureck N, Graumann J, Weinstein LS, Offermanns S.

J Clin Invest. 2019 Jun 17;129(7):2775-2791. doi: 10.1172/JCI123825. eCollection 2019 Jun 17.

10.

AKAP12 deficiency impairs VEGF-induced endothelial cell migration and sprouting.

Benz PM, Ding Y, Stingl H, Loot AE, Zink J, Wittig I, Popp R, Fleming I.

Acta Physiol (Oxf). 2019 Jun 4:e13325. doi: 10.1111/apha.13325. [Epub ahead of print]

PMID:
31162891
11.

Anomalous Kv 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2 S and persulfidation in skeletal muscle.

Vellecco V, Martelli A, Bibli IS, Vallifuoco M, Manzo OL, Panza E, Citi V, Calderone V, de Dominicis G, Cozzolino C, Basso EM, Mariniello M, Fleming I, Mancini A, Bucci M, Cirino G.

Br J Pharmacol. 2019 May 3. doi: 10.1111/bph.14700. [Epub ahead of print]

PMID:
31051045
12.

Epigenetic control of the angiotensin-converting enzyme in endothelial cells during inflammation.

Mudersbach T, Siuda D, Kohlstedt K, Fleming I.

PLoS One. 2019 May 1;14(5):e0216218. doi: 10.1371/journal.pone.0216218. eCollection 2019.

13.

Estimating the relative fitness of escaped farmed salmon offspring in the wild and modelling the consequences of invasion for wild populations.

Sylvester EVA, Wringe BF, Duffy SJ, Hamilton LC, Fleming IA, Castellani M, Bentzen P, Bradbury IR.

Evol Appl. 2019 Jan 28;12(4):705-717. doi: 10.1111/eva.12746. eCollection 2019 Apr.

14.

Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins.

Fuhrmann DC, Olesch C, Kurrle N, Schnütgen F, Zukunft S, Fleming I, Brüne B.

Cells. 2019 Feb 18;8(2). pii: E172. doi: 10.3390/cells8020172.

15.

Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA).

Lowe PT, Dall'Angelo S, Fleming IN, Piras M, Zanda M, O'Hagan D.

Org Biomol Chem. 2019 Feb 6;17(6):1480-1486. doi: 10.1039/c8ob03150a.

PMID:
30681115
16.

Can variation in standard metabolic rate explain context-dependent performance of farmed Atlantic salmon offspring?

Robertsen G, Reid D, Einum S, Aronsen T, Fleming IA, Sundt-Hansen LE, Karlsson S, Kvingedal E, Ugedal O, Hindar K.

Ecol Evol. 2018 Dec 26;9(1):212-222. doi: 10.1002/ece3.4716. eCollection 2019 Jan.

17.

ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function.

Baal N, Cunningham S, Obermann HL, Thomas J, Lippitsch A, Dietert K, Gruber AD, Kaufmann A, Michel G, Nist A, Stiewe T, Rupp O, Goesmann A, Zukunft S, Fleming I, Bein G, Lohmeyer J, Bauer S, Hackstein H.

J Immunol. 2019 Feb 15;202(4):1099-1111. doi: 10.4049/jimmunol.1800269. Epub 2019 Jan 16.

PMID:
30651342
18.

Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase.

Namgaladze D, Zukunft S, Schnütgen F, Kurrle N, Fleming I, Fuhrmann D, Brüne B.

Front Immunol. 2018 Dec 4;9:2858. doi: 10.3389/fimmu.2018.02858. eCollection 2018.

19.

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.

Riddell M, Nakayama A, Hikita T, Mirzapourshafiyi F, Kawamura T, Pasha A, Li M, Masuzawa M, Looso M, Steinbacher T, Ebnet K, Potente M, Hirose T, Ohno S, Fleming I, Gattenlöhner S, Aung PP, Phung T, Yamasaki O, Yanagi T, Umemura H, Nakayama M.

Nat Commun. 2018 Dec 17;9(1):5357. doi: 10.1038/s41467-018-07739-0.

20.

Association between arginase-containing platelet-derived microparticles and altered plasma arginine metabolism in polycystic ovary syndrome.

Kyselova A, Hinrichsmeyer H, Zukunft S, Mann AW, Dornauf I, Fleming I, Randriamboavonjy V.

Metabolism. 2019 Jan;90:16-19. doi: 10.1016/j.metabol.2018.10.008. Epub 2018 Oct 24.

PMID:
30367832
21.

Extensive hybridization following a large escape of domesticated Atlantic salmon in the Northwest Atlantic.

Wringe BF, Jeffery NW, Stanley RRE, Hamilton LC, Anderson EC, Fleming IA, Grant C, Dempson JB, Veinott G, Duffy SJ, Bradbury IR.

Commun Biol. 2018 Aug 9;1:108. doi: 10.1038/s42003-018-0112-9. eCollection 2018.

22.

Redox Regulation of Calpains: Consequences on Vascular Function.

Randriamboavonjy V, Kyselova A, Fleming I.

Antioxid Redox Signal. 2019 Mar 1;30(7):1011-1026. doi: 10.1089/ars.2018.7607. Epub 2018 Nov 15.

PMID:
30266074
23.

Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation.

Zippel N, Loot AE, Stingl H, Randriamboavonjy V, Fleming I, Fisslthaler B.

Int J Mol Sci. 2018 Sep 13;19(9). pii: E2753. doi: 10.3390/ijms19092753.

24.

Platelet communication with the vascular wall: role of platelet-derived microparticles and non-coding RNAs.

Randriamboavonjy V, Fleming I.

Clin Sci (Lond). 2018 Sep 5;132(17):1875-1888. doi: 10.1042/CS20180580. Print 2018 Sep 14. Review.

PMID:
30185611
25.

Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug.

Bibli SI, Papapetropoulos A, Iliodromitis EK, Daiber A, Randriamboavonjy V, Steven S, Brouckaert P, Chatzianastasiou A, Kypreos KE, Hausenloy DJ, Fleming I, Andreadou I.

Cardiovasc Res. 2019 Mar 1;115(3):625-636. doi: 10.1093/cvr/cvy222.

PMID:
30165375
26.

A selective and sensitive method for quantification of endogenous polysulfide production in biological samples.

Bibli SI, Luck B, Zukunft S, Wittig J, Chen W, Xian M, Papapetropoulos A, Hu J, Fleming I.

Redox Biol. 2018 Sep;18:295-304. doi: 10.1016/j.redox.2018.07.016. Epub 2018 Jul 21.

27.

The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase.

Vasconez AE, Janetzko P, Oo JA, Pflüger-Müller B, Ratiu C, Gu L, Helin K, Geisslinger G, Fleming I, Schröder K, Fork C, Brandes RP, Leisegang MS.

Acta Physiol (Oxf). 2019 Jan;225(1):e13168. doi: 10.1111/apha.13168. Epub 2018 Aug 25.

PMID:
30076673
28.

Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy.

Nicolay JP, Thorn V, Daniel C, Amann K, Siraskar B, Lang F, Hillgruber C, Goerge T, Hoffmann S, Gorzelanny C, Huck V, Mess C, Obser T, Schneppenheim R, Fleming I, Schneider MF, Schneider SW.

Sci Rep. 2018 Jul 19;8(1):10945. doi: 10.1038/s41598-018-28961-2.

29.

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.

Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I.

Circulation. 2019 Jan 2;139(1):101-114. doi: 10.1161/CIRCULATIONAHA.118.034757.

PMID:
29970364
30.

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.

Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP.

Nat Commun. 2018 Jun 12;9(1):2292. doi: 10.1038/s41467-018-04602-0.

31.

Angiogenesis and vascular stability in eicosanoids and cancer.

Hu J, Frömel T, Fleming I.

Cancer Metastasis Rev. 2018 Sep;37(2-3):425-438. doi: 10.1007/s10555-018-9732-2. Review.

PMID:
29808461
32.

Estimating degradation-related settlement in two landfill-reclaimed soils by sand-salt analogues.

McDougall JR, Fleming IR, Thiel R, Dewaele P, Parker D, Kelly D.

Waste Manag. 2018 Jul;77:294-303. doi: 10.1016/j.wasman.2018.04.013. Epub 2018 Apr 26.

PMID:
29705046
33.

Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells.

Cencioni C, Spallotta F, Savoia M, Kuenne C, Guenther S, Re A, Wingert S, Rehage M, Sürün D, Siragusa M, Smith JG, Schnütgen F, von Melchner H, Rieger MA, Martelli F, Riccio A, Fleming I, Braun T, Zeiher AM, Farsetti A, Gaetano C.

Nat Commun. 2018 Mar 29;9(1):1281. doi: 10.1038/s41467-018-03668-0.

34.

Role of the angiotensin-converting enzyme in the G-CSF-induced mobilization of progenitor cells.

Kohlstedt K, Trouvain C, Frömel T, Mudersbach T, Henschler R, Fleming I.

Basic Res Cardiol. 2018 Mar 17;113(3):18. doi: 10.1007/s00395-018-0677-y.

PMID:
29549541
35.

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

Laban H, Weigert A, Zink J, Elgheznawy A, Schürmann C, Günther L, Abdel Malik R, Bothur S, Wingert S, Bremer R, Rieger MA, Brüne B, Brandes RP, Fleming I, Benz PM.

J Cell Biol. 2018 Apr 2;217(4):1503-1519. doi: 10.1083/jcb.201702048. Epub 2018 Mar 5.

36.

Characterization of Athabasca lean oil sands and mixed surficial materials: Comparison of capillary electrophoresis/low-resolution mass spectrometry and high-resolution mass spectrometry.

MacLennan MS, Peru KM, Swyngedouw C, Fleming I, Chen DDY, Headley JV.

Rapid Commun Mass Spectrom. 2018 May 15;32(9):695-702. doi: 10.1002/rcm.8093.

PMID:
29486520
37.

Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses.

Zezina E, Snodgrass RG, Schreiber Y, Zukunft S, Schürmann C, Heringdorf DMZ, Geisslinger G, Fleming I, Brandes RP, Brüne B, Namgaladze D.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):433-446. doi: 10.1016/j.bbalip.2018.01.009.

PMID:
29360568
38.

Phosphorylation of vasodilator-stimulated phosphoprotein contributes to myocardial ischemic preconditioning.

Köhler D, Bibli SI, Klammer LP, Roth JM, Lehmann R, Fleming I, Granja TF, Straub A, Benz PM, Rosenberger P.

Basic Res Cardiol. 2018 Jan 17;113(2):11. doi: 10.1007/s00395-018-0667-0.

PMID:
29344719
39.

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.

Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I.

Nature. 2017 Dec 14;552(7684):248-252. doi: 10.1038/nature25013. Epub 2017 Dec 6.

40.

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice.

Rezende F, Moll F, Walter M, Helfinger V, Hahner F, Janetzko P, Ringel C, Weigert A, Fleming I, Weissmann N, Kuenne C, Looso M, Rieger MA, Nawroth P, Fleming T, Brandes RP, Schröder K.

Redox Biol. 2018 May;15:12-21. doi: 10.1016/j.redox.2017.11.014. Epub 2017 Nov 22.

41.

Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients: Rescue by α-Ketoglutarate and TET-TDG Functional Reactivation.

Spallotta F, Cencioni C, Atlante S, Garella D, Cocco M, Mori M, Mastrocola R, Kuenne C, Guenther S, Nanni S, Azzimato V, Zukunft S, Kornberger A, Sürün D, Schnütgen F, von Melchner H, Di Stilo A, Aragno M, Braspenning M, van Criekinge W, De Blasio MJ, Ritchie RH, Zaccagnini G, Martelli F, Farsetti A, Fleming I, Braun T, Beiras-Fernandez A, Botta B, Collino M, Bertinaria M, Zeiher AM, Gaetano C.

Circ Res. 2018 Jan 5;122(1):31-46. doi: 10.1161/CIRCRESAHA.117.311300. Epub 2017 Nov 20.

PMID:
29158345
42.

Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection.

Bibli SI, Szabo C, Chatzianastasiou A, Luck B, Zukunft S, Fleming I, Papapetropoulos A.

Mol Pharmacol. 2017 Dec;92(6):718-730. doi: 10.1124/mol.117.109645. Epub 2017 Oct 13.

PMID:
29030392
43.

Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux.

Ilina EI, Armento A, Sanchez LG, Reichlmeir M, Braun Y, Penski C, Capper D, Sahm F, Jennewein L, Harter PN, Zukunft S, Fleming I, Schulte D, Le Guerroué F, Behrends C, Ronellenfitsch MW, Naumann U, Mittelbronn M.

Oncotarget. 2017 Jun 27;8(40):67567-67591. doi: 10.18632/oncotarget.18747. eCollection 2017 Sep 15.

44.

Platelet-Enriched MicroRNAs and Cardiovascular Homeostasis.

Elgheznawy A, Fleming I.

Antioxid Redox Signal. 2018 Sep 20;29(9):902-921. doi: 10.1089/ars.2017.7289. Epub 2017 Sep 8. Review.

PMID:
28793796
45.

S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β.

Weichand B, Popp R, Dziumbla S, Mora J, Strack E, Elwakeel E, Frank AC, Scholich K, Pierre S, Syed SN, Olesch C, Ringleb J, Ören B, Döring C, Savai R, Jung M, von Knethen A, Levkau B, Fleming I, Weigert A, Brüne B.

J Exp Med. 2017 Sep 4;214(9):2695-2713. doi: 10.1084/jem.20160392. Epub 2017 Jul 24.

46.

Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status.

Andriu A, Crockett J, Dall'Angelo S, Piras M, Zanda M, Fleming IN.

Mol Imaging Biol. 2018 Feb;20(1):27-36. doi: 10.1007/s11307-017-1100-z.

47.

High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging αv β3 Integrin.

Piras M, Testa A, Fleming IN, Dall'Angelo S, Andriu A, Menta S, Mori M, Brown GD, Forster D, Williams KJ, Zanda M.

ChemMedChem. 2017 Jul 20;12(14):1142-1151. doi: 10.1002/cmdc.201700328. Epub 2017 Jul 3.

PMID:
28608961
48.

KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation.

Lazzari P, Spiga M, Sani M, Zanda M, Fleming IN.

Hypoxia (Auckl). 2017 May 23;5:45-59. doi: 10.2147/HP.S132832. eCollection 2017.

49.

Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2.

Bibli SI, Zhou Z, Zukunft S, Fisslthaler B, Andreadou I, Szabo C, Brouckaert P, Fleming I, Papapetropoulos A.

Cardiovasc Res. 2017 Jul 1;113(8):926-937. doi: 10.1093/cvr/cvx058.

PMID:
28444132
50.

Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis.

Hu J, Geyer A, Dziumbla S, Awwad K, Zeldin DC, Schunck WH, Popp R, Frömel T, Fleming I.

Prostaglandins Other Lipid Mediat. 2017 Nov;133:93-102. doi: 10.1016/j.prostaglandins.2017.04.002. Epub 2017 Apr 23.

PMID:
28442442

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