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Pharmacokinetics and Pharmacodynamics of Insulin Tregopil in Relation to Premeal Dosing Time, Between Meal Interval, and Meal Composition in Patients With Type 2 Diabetes Mellitus.

Khedkar A, Lebovitz H, Fleming A, Cherrington A, Jose V, Athalye SN, Vishweswaramurthy A.

Clin Pharmacol Drug Dev. 2019 Aug 7. doi: 10.1002/cpdd.730. [Epub ahead of print]


Proportional Myoelectric Control of a Powered Ankle Prosthesis for Postural Control under Expected Perturbation: A Pilot Study.

Fleming A, Huang HH.

IEEE Int Conf Rehabil Robot. 2019 Jun;2019:899-904. doi: 10.1109/ICORR.2019.8779509.


Effects of Moving the United States Medical Licensing Examination Step 1 After Core Clerkships on Step 2 Clinical Knowledge Performance.

Jurich D, Santen SA, Paniagua M, Fleming A, Harnik V, Pock A, Swan-Sein A, Barone MA, Daniel M.

Acad Med. 2019 Jul 30. doi: 10.1097/ACM.0000000000002921. [Epub ahead of print]


An investigation of the effects of procalcitonin testing on antimicrobial prescribing in respiratory tract infections in an Irish university hospital setting: a feasibility study.

O'Riordan F, Shiely F, Byrne S, O'Brien D, Palmer B, Dahly D, O'Connor TM, Curran D, Fleming A.

J Antimicrob Chemother. 2019 Jul 19. pii: dkz313. doi: 10.1093/jac/dkz313. [Epub ahead of print]


Genome-wide association analysis for β-hydroxybutyrate concentration in Milk in Holstein dairy cattle.

Nayeri S, Schenkel F, Fleming A, Kroezen V, Sargolzaei M, Baes C, Cánovas A, Squires J, Miglior F.

BMC Genet. 2019 Jul 16;20(1):58. doi: 10.1186/s12863-019-0761-9.


Twenty-two new species in the genus Hyphantrophaga Townsend (Diptera: Tachinidae) from Area de Conservación Guanacaste, with a key to the species of Mesoamerica.

Fleming AJ, Wood DM, Smith MA, Dapkey T, Hallwachs W, Janzen D.

Biodivers Data J. 2019 Jun 28;7:e29553. doi: 10.3897/BDJ.7.e29553. eCollection 2019.


Salvage Therapy for Childhood Medulloblastoma: A Single Center Experience.

Kameda-Smith MM, Wang A, Abdulhadi N, Voth R, Sergeant A, Maharaj A, Bakhshinyan D, Adile AA, Pai AM, Ajani O, Yarascavitch B, Alyman MC, Duckworth J, Samaan MC, Farrokhyar F, Singh SK, Fleming A; Pediatric Brain Tumour Study Group.

Can J Neurol Sci. 2019 Jul;46(4):403-414. doi: 10.1017/cjn.2019.39.


The Costs of Applying to Residency: One Institution's Efforts to Increase Transparency.

Kuhn AW, Jarrett RT, Scudder DR, Pereira DE, Fleming AE, Drolet BC.

South Med J. 2019 Jul;112(7):376-381. doi: 10.14423/SMJ.0000000000000995.


Mesophyll porosity is modulated by the presence of functional stomata.

Lundgren MR, Mathers A, Baillie AL, Dunn J, Wilson MJ, Hunt L, Pajor R, Fradera-Soler M, Rolfe S, Osborne CP, Sturrock CJ, Gray JE, Mooney SJ, Fleming AJ.

Nat Commun. 2019 Jun 27;10(1):2825. doi: 10.1038/s41467-019-10826-5.


Human NEIL3 Gene Expression Regulated by Epigenetic-Like Oxidative DNA Modification.

Fleming AM, Zhu J, Howpay Manage SA, Burrows CJ.

J Am Chem Soc. 2019 Jul 17;141(28):11036-11049. doi: 10.1021/jacs.9b01847. Epub 2019 Jul 8.


Proportional Myoelectric Control of a Virtual Inverted Pendulum Using Residual Antagonistic Muscles: Toward Voluntary Postural Control.

Fleming A, Huang S, Huang H.

IEEE Trans Neural Syst Rehabil Eng. 2019 Jul;27(7):1473-1482. doi: 10.1109/TNSRE.2019.2922102. Epub 2019 Jun 10.


Reduced stomatal density in bread wheat leads to increased water-use efficiency.

Dunn J, Hunt L, Afsharinafar M, Al Meselmani M, Mitchell A, Howells R, Wallington E, Fleming AJ, Gray JE.

J Exp Bot. 2019 Jun 6. pii: erz248. doi: 10.1093/jxb/erz248. [Epub ahead of print]


Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC.

Nat Commun. 2019 Jun 4;10(1):2530. doi: 10.1038/s41467-019-10536-y.


Maternal symptoms of depression and sensitivity mediate the relation between maternal history of early adversity and her child temperament: The inheritance of circumstance.

Bouvette-Turcot AA, Fleming AS, Unternaehrer E, Gonzalez A, Atkinson L, Gaudreau H, Steiner M, Meaney MJ.

Dev Psychopathol. 2019 Jun 3:1-9. doi: 10.1017/S0954579419000488. [Epub ahead of print]


Acute Chest Syndrome After Splenectomy in Children With Sickle Cell Disease.

El-Gohary Y, Fleming A, Zhang H, Estepp JH, Hankins JS, Wang W, Davidoff AM, Murphy AJ.

J Surg Res. 2019 Oct;242:336-341. doi: 10.1016/j.jss.2019.04.077. Epub 2019 May 23.


Evaluating the prevalence of diabetes mellitus subtypes in childhood cancer survivors: a systematic review protocol.

Chen SSJ, Nadarajah A, Banfield L, Fleming A, Thabane L, Portwine C, Samaan MC.

Adolesc Health Med Ther. 2019 Apr 26;10:59-65. doi: 10.2147/AHMT.S199449. eCollection 2019.


Association of Herpes Simplex Virus Testing with Hospital Length of Stay for Infants ≤60 Days of Age Undergoing Evaluation for Meningitis.

Aronson PL, Cruz AT, Freedman SB, Balamuth F, Grether-Jones KL, Lyons TW, Fleming AH, Louie J, Mistry RD, Garro AC, Shah SS, Nigrovic LE; Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus (HSV) Study Group.

J Hosp Med. 2019 Aug 1;14(8):492-495. doi: 10.12788/jhm.3202. Epub 2019 May 12.


The UCD nanosafety workshop (03 December 2018): towards developing a consensus on safe handling of nanomaterials within the Irish university labs and beyond - a report.

Stuttgen V, Giffney HE, Anandan A, Alabdali A, Twarog C, Belhout SA, O Loughlin M, Podhorska L, Delaney C, Geoghegan N, Mc-Fadden J, Alhadhrami NA, Fleming A, Phadke S, Yadav R, Fattah S, McCartney F, Alsharif SA, McCaul J, Singh K, Erikandath S, O Meara F, Wychowaniec JK, Cutrona MB, MacMaster G, Reynolds AL, Gaines S, Hogg B, Farrelly M, D Alton M, Coulahan P, Bhattacharjee S.

Nanotoxicology. 2019 Aug;13(6):717-732. doi: 10.1080/17435390.2019.1621402. Epub 2019 Jun 20.


Corrigendum to: Heavy with child? Pregnancy status and stable isotope ratios as determined from biopsies of humpback whales.

Clark CT, Fleming AH, Calambokidis J, Kellar NM, Allen CD, Catelani KN, Robbins M, Beaulieu NE, Steel D, Harvey JT.

Conserv Physiol. 2019 May 10;7(1):coz013. doi: 10.1093/conphys/coz013. eCollection 2019.


Distribution of Non-perfusion and Neovascularization on Ultra-Wide Field Fluorescein Angiography in Proliferative Diabetic Retinopathy (RECOVERY Study): Report 1.

Fan W, Nittala MG, Velaga SB, Hirano T, Wykoff CC, Ip M, Lampen SIR, van Hemert J, Fleming A, Verhoek M, Sadda SR.

Am J Ophthalmol. 2019 May 9. pii: S0002-9394(19)30204-1. doi: 10.1016/j.ajo.2019.04.023. [Epub ahead of print]


A new species of Trismegistomya Reinhard (Diptera: Tachinidae) from Area de Conservación Guanacaste in northwestern Costa Rica.

Fleming AJ, Wood DM, Smith MA, Dapkey T, Hallwachs W, Janzen DH.

Biodivers Data J. 2019 Apr 10;7:e29130. doi: 10.3897/BDJ.7.e29130. eCollection 2019.


Lincoln center moments: integrating accessibility and enhancement through expanding performing arts experiences.

Loewy J, Torossian A, Appelbaum M, Fleming A, Tomaino C.

Arts Health. 2019 Feb 4:1-12. doi: 10.1080/17533015.2018.1555177. [Epub ahead of print]


Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine.

An N, Fleming AM, Rosecrans NC, Liao Y, Burrows CJ.

Methods Mol Biol. 2019;1973:15-25. doi: 10.1007/978-1-4939-9216-4_2.


Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC.

Nat Commun. 2019 Apr 18;10(1):1817. doi: 10.1038/s41467-019-09494-2. Erratum in: Nat Commun. 2019 Jun 4;10(1):2530.


Real-World Evidence Should Be Used in Regulatory Decisions About New Pharmaceutical and Medical Device Products for Diabetes.

Klonoff DC, Gutierrez A, Fleming A, Kerr D.

J Diabetes Sci Technol. 2019 Apr 3:1932296819839996. doi: 10.1177/1932296819839996. [Epub ahead of print]


Defining Learning Communities in Undergraduate Medical Education: A National Study.

Shochet R, Fleming A, Wagner J, Colbert-Getz J, Bhutiani M, Moynahan K, Keeley M.

J Med Educ Curric Dev. 2019 Mar 24;6:2382120519827911. doi: 10.1177/2382120519827911. eCollection 2019 Jan-Dec.


Does cellular metabolism from primary fibroblasts and oxidative stress in blood differ between mammals and birds? The (lack-thereof) scaling of oxidative stress.

Jimenez AG, O'Connor ES, Tobin KJ, Anderson KN, Winward JD, Fleming A, Winner C, Chinchilli E, Amy M, Carlson K, Downs CJ.

Integr Comp Biol. 2019 Mar 29. pii: icz017. doi: 10.1093/icb/icz017. [Epub ahead of print]


Too Many Hats? Conflicts of Interest in Learning Community Faculty Roles.

Gliatto P, Colbert-Getz JM, Bhutiani M, Cutrer WB, Edwards S, Fleming A, Keeley M, Osterberg L, Pilla MA, Moynahan K.

J Med Educ Curric Dev. 2019 Mar 22;6:2382120519827890. doi: 10.1177/2382120519827890. eCollection 2019 Jan-Dec.


Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress.

Fleming AM, Zhu J, Ding Y, Burrows CJ.

Nucleic Acids Res. 2019 Jun 4;47(10):5049-5060. doi: 10.1093/nar/gkz207.


Maternal care activates the ventral tegmental area but not dopaminergic cells in the rat.

Caba M, Melo AI, Fleming A, Meza E.

J Neuroendocrinol. 2019 Mar 26:e12713. doi: 10.1111/jne.12713. [Epub ahead of print]


Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR.

Immunity. 2019 Apr 16;50(4):1099-1114.e10. doi: 10.1016/j.immuni.2019.02.006. Epub 2019 Mar 12.


Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution.

Khoddami V, Yerra A, Mosbruger TL, Fleming AM, Burrows CJ, Cairns BR.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14. Erratum in: Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9136.


Draft Genome Sequence and Annotation of Acinetobacter junii MHI21018, Isolated from Bovine Colostrum.

Kröger C, Schauer K, Clerkin SR, Märtlbauer E, Fleming AB.

Microbiol Resour Announc. 2019 Mar 7;8(10). pii: e01700-18. doi: 10.1128/MRA.01700-18. eCollection 2019 Mar.


Inter-individual maternal care received and genotype interactions affect dopaminergic phenotypes in female rat offspring.

Lauby SC, Chatterjee D, Pan P, McGowan PO, Fleming AS.

J Neuroendocrinol. 2019 Mar 12:e12706. doi: 10.1111/jne.12706. [Epub ahead of print]


Assessing bioavailability of ruminally protected methionine and lysine prototypes.

Fleming AJ, Estes KA, Choi H, Barton BA, Zimmerman CA, Hanigan MD.

J Dairy Sci. 2019 May;102(5):4014-4024. doi: 10.3168/jds.2018-14667. Epub 2019 Mar 7.


Colocalization of m6A and G-Quadruplex-Forming Sequences in Viral RNA (HIV, Zika, Hepatitis B, and SV40) Suggests Topological Control of Adenosine N 6-Methylation.

Fleming AM, Nguyen NLB, Burrows CJ.

ACS Cent Sci. 2019 Feb 27;5(2):218-228. doi: 10.1021/acscentsci.8b00963. Epub 2019 Feb 4. Review.


Oxidative Modification of Guanine in a Potential Z-DNA-Forming Sequence of a Gene Promoter Impacts Gene Expression.

Fleming AM, Zhu J, Ding Y, Esders S, Burrows CJ.

Chem Res Toxicol. 2019 May 20;32(5):899-909. doi: 10.1021/acs.chemrestox.9b00041. Epub 2019 Mar 7.


Impact of DNA Oxidation on Toxicology: From Quantification to Genomics.

Wu J, Sturla SJ, Burrows CJ, Fleming AM.

Chem Res Toxicol. 2019 Mar 18;32(3):345-347. doi: 10.1021/acs.chemrestox.9b00046. Epub 2019 Feb 26.


Motivational Advising Workshop: Utilizing Motivational Interviewing Theory to Facilitate and Engage Intrinsic Motivation to Change Learners' Behavior.

Parekh K, Benningfield M, Burrows H, Fleming A, Golden WC, Keeley M, Kileny S, Klink TE.

MedEdPORTAL. 2018 Sep 18;14:10751. doi: 10.15766/mep_2374-8265.10751.


Automated detection of age-related macular degeneration in color fundus photography: a systematic review.

Pead E, Megaw R, Cameron J, Fleming A, Dhillon B, Trucco E, MacGillivray T.

Surv Ophthalmol. 2019 Jul - Aug;64(4):498-511. doi: 10.1016/j.survophthal.2019.02.003. Epub 2019 Feb 14.


Challenges Associated With Moving the United States Medical Licensing Examination (USMLE) Step 1 to After the Core Clerkships and How to Approach Them.

Pock A, Daniel M, Santen SA, Swan-Sein A, Fleming A, Harnik V.

Acad Med. 2019 Jun;94(6):775-780. doi: 10.1097/ACM.0000000000002651.


An integrated device for the rapid and sensitive detection of the influenza hemagglutinin.

Anderson CE, Buser JR, Fleming AM, Strauch EM, Ladd PD, Englund J, Baker D, Yager P.

Lab Chip. 2019 Feb 26;19(5):885-896. doi: 10.1039/c8lc00691a.


Symposium review: The choice and collection of new relevant phenotypes for fertility selection.

Fleming A, Baes CF, Martin AAA, Chud TCS, Malchiodi F, Brito LF, Miglior F.

J Dairy Sci. 2019 Apr;102(4):3722-3734. doi: 10.3168/jds.2018-15470. Epub 2019 Feb 1. Review.


Pomalidomide Alters Pancreatic Macrophage Populations to Generate an Immune-Responsive Environment at Precancerous and Cancerous Lesions.

Bastea LI, Liou GY, Pandey V, Fleming AK, von Roemeling CA, Doeppler H, Li Z, Qiu Y, Edenfield B, Copland JA, Tun HW, Storz P.

Cancer Res. 2019 Apr 1;79(7):1535-1548. doi: 10.1158/0008-5472.CAN-18-1153. Epub 2019 Jan 29.


Guidance of sentinel lymph node biopsy decisions in patients with T1-T2 melanoma using gene expression profiling.

Vetto JT, Hsueh EC, Gastman BR, Dillon LD, Monzon FA, Cook RW, Keller J, Huang X, Fleming A, Hewgley P, Gerami P, Leachman S, Wayne JD, Berger AC, Fleming MD.

Future Oncol. 2019 Apr;15(11):1207-1217. doi: 10.2217/fon-2018-0912. Epub 2019 Jan 29.


Symposium review: The genomic architecture of inbreeding: How homozygosity affects health and performance.

Baes CF, Makanjuola BO, Miglior F, Marras G, Howard JT, Fleming A, Maltecca C.

J Dairy Sci. 2019 Mar;102(3):2807-2817. doi: 10.3168/jds.2018-15520. Epub 2019 Jan 17.


Mistreatment of Medical Trainees: Time for a New Approach.

Fleming AE, Smith S.

JAMA Netw Open. 2018 Jul 6;1(3):e180869. doi: 10.1001/jamanetworkopen.2018.0869. No abstract available.


Oxidative Modification of the Potential G-Quadruplex Sequence in the PCNA Gene Promoter Can Turn on Transcription.

Redstone SCJ, Fleming AM, Burrows CJ.

Chem Res Toxicol. 2019 Mar 18;32(3):437-446. doi: 10.1021/acs.chemrestox.8b00332. Epub 2019 Jan 14.


Impact of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open-Label, Placebo-Controlled, Crossover Study.

Khedkar A, Lebovitz H, Fleming A, Cherrington A, Jose V, Athalye SN, Vishweswaramurthy A.

Clin Transl Sci. 2019 May;12(3):276-282. doi: 10.1111/cts.12609. Epub 2019 Feb 12.


A landscape of the heritability of Fourier-transform infrared spectral wavelengths of milk samples by parity and lactation stage in Holstein cows.

Rovere G, de Los Campos G, Tempelman RJ, Vazquez AI, Miglior F, Schenkel F, Cecchinato A, Bittante G, Toledo-Alvarado H, Fleming A.

J Dairy Sci. 2019 Feb;102(2):1354-1363. doi: 10.3168/jds.2018-15109. Epub 2018 Dec 20.


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