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Items: 1 to 50 of 77

1.

Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma.

Dong X, Zhang R, He J, Lai L, Alolga RN, Shen S, Zhu Y, You D, Lin L, Chen C, Zhao Y, Duan W, Su L, Shafer A, Salama M, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC.

Aging (Albany NY). 2019 Aug 21;11(16):6312-6335. doi: 10.18632/aging.102189. Epub 2019 Aug 21.

2.

Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data.

Lai X, Geier OM, Fleischer T, Garred Ø, Borgen E, Funke SW, Kumar S, Rognes ME, Seierstad T, Børresen-Dale AL, Kristensen VN, Engebraaten O, Köhn-Luque A, Frigessi A.

Cancer Res. 2019 Aug 15;79(16):4293-4304. doi: 10.1158/0008-5472.CAN-18-1804. Epub 2019 May 22.

PMID:
31118201
3.

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.

Brinkman AB, Nik-Zainal S, Simmer F, Rodríguez-González FG, Smid M, Alexandrov LB, Butler A, Martin S, Davies H, Glodzik D, Zou X, Ramakrishna M, Staaf J, Ringnér M, Sieuwerts A, Ferrari A, Morganella S, Fleischer T, Kristensen V, Gut M, van de Vijver MJ, Børresen-Dale AL, Richardson AL, Thomas G, Gut IG, Martens JWM, Foekens JA, Stratton MR, Stunnenberg HG.

Nat Commun. 2019 Apr 15;10(1):1749. doi: 10.1038/s41467-019-09828-0.

4.

SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis.

Zhang R, Lai L, Dong X, He J, You D, Chen C, Lin L, Zhu Y, Huang H, Shen S, Wei L, Chen X, Guo Y, Liu L, Su L, Shafer A, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC.

Mol Oncol. 2019 May;13(5):1235-1248. doi: 10.1002/1878-0261.12482. Epub 2019 Apr 17.

5.

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC.

Zhang R, Lai L, He J, Chen C, You D, Duan W, Dong X, Zhu Y, Lin L, Shen S, Guo Y, Su L, Shafer A, Moran S, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC.

Epigenetics. 2019 Feb;14(2):118-129. doi: 10.1080/15592294.2019.1573066. Epub 2019 Jan 31.

PMID:
30665327
6.

Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations.

Höglander EK, Nord S, Wedge DC, Lingjærde OC, Silwal-Pandit L, Gythfeldt HV, Vollan HKM, Fleischer T, Krohn M, Schlitchting E, Borgen E, Garred Ø, Holmen MM, Wist E, Naume B, Van Loo P, Børresen-Dale AL, Engebraaten O, Kristensen V.

Genome Med. 2018 Nov 29;10(1):92. doi: 10.1186/s13073-018-0601-y.

7.

Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab.

Jabeen S, Zucknick M, Nome M, Dannenfelser R, Fleischer T, Kumar S, Lüders T, von der Lippe Gythfeldt H, Troyanskaya O, Kyte JA, Børresen-Dale AL, Naume B, Tekpli X, Engebraaten O, Kristensen V.

Oncoimmunology. 2018 Aug 6;7(11):e1457598. doi: 10.1080/2162402X.2018.1457598. eCollection 2018.

8.

DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients.

Guo Y, Zhang R, Shen S, Wei Y, Salama SM, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Su L, Zhu Z, Staaf J, Helland Å, Esteller M, Christiani DC.

Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1527-1535. doi: 10.1158/1055-9965.EPI-18-0454. Epub 2018 Sep 5.

PMID:
30185536
9.

A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer.

Shen S, Zhang R, Guo Y, Loehrer E, Wei Y, Zhu Y, Yuan Q, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Su L, Chen F, Christiani DC.

Mol Oncol. 2018 Jun;12(6):913-924. doi: 10.1002/1878-0261.12204. Epub 2018 May 4.

10.

Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC.

Wei Y, Liang J, Zhang R, Guo Y, Shen S, Su L, Lin X, Moran S, Helland Å, Bjaanæs MM, Karlsson A, Planck M, Esteller M, Fleischer T, Staaf J, Zhao Y, Chen F, Christiani DC.

Clin Epigenetics. 2018 Apr 2;10:41. doi: 10.1186/s13148-018-0474-3. eCollection 2018.

11.

A Controlled Trial of Sheng-Yu-Tang for Post-Hematopoietic Stem Cell Transplantation Leukemia Patients: A Proposed Protocol and Insights From a Preliminary Pilot Study.

Fleischer T, Chang TT, Chiang JH, Yen HR.

Integr Cancer Ther. 2018 Sep;17(3):665-673. doi: 10.1177/1534735418756736. Epub 2018 Feb 11.

12.

DNA methylation at enhancers identifies distinct breast cancer lineages.

Fleischer T, Tekpli X, Mathelier A, Wang S, Nebdal D, Dhakal HP, Sahlberg KK, Schlichting E; Oslo Breast Cancer Research Consortium (OSBREAC), Børresen-Dale AL, Borgen E, Naume B, Eskeland R, Frigessi A, Tost J, Hurtado A, Kristensen VN.

Nat Commun. 2017 Nov 9;8(1):1379. doi: 10.1038/s41467-017-00510-x.

13.

Rare catastrophic events drive population dynamics in a bat species with negligible senescence.

Fleischer T, Gampe J, Scheuerlein A, Kerth G.

Sci Rep. 2017 Aug 4;7(1):7370. doi: 10.1038/s41598-017-06392-9.

14.

The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer.

Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlitchting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen V, Langerød A, Lundgren S, Wist E, Naume B, Lingjærde OC, Børresen-Dale AL, Engebraaten O.

Clin Cancer Res. 2017 Aug 15;23(16):4662-4670. doi: 10.1158/1078-0432.CCR-17-0160. Epub 2017 May 9.

15.

How do government regulations influence the ability to practice Chinese herbal medicine in western countries.

Fleischer T, Su YC, Lin SJ.

J Ethnopharmacol. 2017 Jan 20;196:104-109. doi: 10.1016/j.jep.2016.11.047. Epub 2016 Dec 1.

16.

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival.

Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN.

Oncotarget. 2017 Jan 3;8(1):1074-1082. doi: 10.18632/oncotarget.13718.

17.

Post-hematopoietic stem cell transplantation in patients with hematologic disorders: Chinese herbal medicine for an unmet need.

Fleischer T, Chang TT, Yen HR.

J Integr Med. 2016 Sep;14(5):322-35. doi: 10.1016/S2095-4964(16)60270-4. Review.

PMID:
27641605
18.

Improved Survival With Integration of Chinese Herbal Medicine Therapy in Patients With Acute Myeloid Leukemia: A Nationwide Population-Based Cohort Study.

Fleischer T, Chang TT, Chiang JH, Sun MF, Yen HR.

Integr Cancer Ther. 2017 Jun;16(2):156-164. doi: 10.1177/1534735416664171. Epub 2016 Aug 16.

19.

Integration of Chinese Herbal Medicine Therapy Improves Survival of Patients With Chronic Lymphocytic Leukemia: A Nationwide Population-Based Cohort Study.

Fleischer T, Chang TT, Chiang JH, Hsieh CY, Sun MF, Yen HR.

Medicine (Baltimore). 2016 May;95(21):e3788. doi: 10.1097/MD.0000000000003788.

20.

Development and validation of a spontaneous preterm delivery predictor in asymptomatic women.

Saade GR, Boggess KA, Sullivan SA, Markenson GR, Iams JD, Coonrod DV, Pereira LM, Esplin MS, Cousins LM, Lam GK, Hoffman MK, Severinsen RD, Pugmire T, Flick JS, Fox AC, Lueth AJ, Rust SR, Mazzola E, Hsu C, Dufford MT, Bradford CL, Ichetovkin IE, Fleischer TC, Polpitiya AD, Critchfield GC, Kearney PE, Boniface JJ, Hickok DE.

Am J Obstet Gynecol. 2016 May;214(5):633.e1-633.e24. doi: 10.1016/j.ajog.2016.02.001. Epub 2016 Feb 11.

21.

Adjunctive Chinese Herbal Medicine therapy improves survival of patients with chronic myeloid leukemia: a nationwide population-based cohort study.

Fleischer T, Chang TT, Chiang JH, Chang CM, Hsieh CY, Yen HR.

Cancer Med. 2016 Apr;5(4):640-8. doi: 10.1002/cam4.627. Epub 2016 Jan 15.

22.

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis.

Bjaanæs MM, Fleischer T, Halvorsen AR, Daunay A, Busato F, Solberg S, Jørgensen L, Kure E, Edvardsen H, Børresen-Dale AL, Brustugun OT, Tost J, Kristensen V, Helland Å.

Mol Oncol. 2016 Feb;10(2):330-43. doi: 10.1016/j.molonc.2015.10.021. Epub 2015 Nov 6.

23.

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.

Johnson KC, Koestler DC, Fleischer T, Chen P, Jenson EG, Marotti JD, Onega T, Kristensen VN, Christensen BC.

Clin Epigenetics. 2015 Jul 25;7:75. doi: 10.1186/s13148-015-0094-0. eCollection 2015.

24.

Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes.

Győrffy B, Bottai G, Fleischer T, Munkácsy G, Budczies J, Paladini L, Børresen-Dale AL, Kristensen VN, Santarpia L.

Int J Cancer. 2016 Jan 1;138(1):87-97. doi: 10.1002/ijc.29684. Epub 2015 Jul 30. Review.

25.

DNA methylation status of key cell-cycle regulators such as CDKNA2/p16 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors.

Klajic J, Busato F, Edvardsen H, Touleimat N, Fleischer T, Bukholm I, Børresen-Dale AL, Lønning PE, Tost J, Kristensen VN.

Clin Cancer Res. 2014 Dec 15;20(24):6357-66. doi: 10.1158/1078-0432.CCR-14-0297. Epub 2014 Oct 7.

26.

Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis.

Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN.

Genome Biol. 2014;15(8):435. doi: 10.1186/PREACCEPT-2333349012841587. Epub 2014 Aug 22.

27.

Chemical constituents from Gouania longipetala and Glyphaea brevis.

Ekuadzi E, Dickson RA, Fleischer TC, Amponsah IK, Pistorius D, Oberer L.

Nat Prod Res. 2014;28(15):1210-3. doi: 10.1080/14786419.2014.921685. Epub 2014 Jun 9.

PMID:
24910899
28.

Research ethics capacity building in Sub-Saharan Africa: a review of NIH Fogarty-funded programs 2000–2012.

Ndebele P, Wassenaar D, Benatar S, Fleischer T, Kruger M, Adebamowo C, Kass N, Hyder AA, Meslin EM.

J Empir Res Hum Res Ethics. 2014 Apr;9(2):24-40. doi: 10.1525/jer.2014.9.2.24. Review.

29.

Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy.

Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H.

Int J Cancer. 2014 Nov 1;135(9):2085-95. doi: 10.1002/ijc.28862. Epub 2014 Apr 5.

30.

Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients.

Fleischer T, Edvardsen H, Solvang HK, Daviaud C, Naume B, Børresen-Dale AL, Kristensen VN, Tost J.

Int J Cancer. 2014 Jun 1;134(11):2615-25. doi: 10.1002/ijc.28606. Epub 2014 Jan 6.

31.

The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors.

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V.

Mol Oncol. 2014 Mar;8(2):273-84. doi: 10.1016/j.molonc.2013.11.008. Epub 2013 Dec 3.

32.

Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors.

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN.

Genome Biol. 2013 Nov 20;14(11):R126. doi: 10.1186/gb-2013-14-11-r126.

33.

Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors.

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN.

BMC Cancer. 2013 Oct 5;13:456. doi: 10.1186/1471-2407-13-456.

34.

Flavonoid glycosides from the stem bark of Margaritaria discoidea demonstrate antibacterial and free radical scavenging activities.

Ekuadzi E, Dickson R, Fleischer T, Annan K, Pistorius D, Oberer L, Gibbons S.

Phytother Res. 2014 May;28(5):784-7. doi: 10.1002/ptr.5053. Epub 2013 Aug 22.

PMID:
23970448
35.

Improving resource allocation decisions for health and HIV programmes in South Africa: Bioethical, cost-effectiveness and health diplomacy considerations.

Kevany S, Benatar SR, Fleischer T.

Glob Public Health. 2013;8(5):570-87. doi: 10.1080/17441692.2013.790461. Epub 2013 May 7.

PMID:
23651436
36.

Participation in 'big style': first observations at the German citizens' dialogue on future technologies.

Decker M, Fleischer T.

Poiesis Prax. 2012 Nov;9(1-2):81-99. Epub 2012 Nov 16.

37.

Anti-inflammatory and antioxidant activities of the leaves of Wissadula amplissima var Rostrata.

Mensah AY, Donkor PO, Fleischer TC.

Afr J Tradit Complement Altern Med. 2011;8(2):185-95. Epub 2010 Dec 30.

38.

Anti-inflammatory, antioxidant, and selective antibacterial effects of Euadenia eminens root bark.

Dickson R, Fleischer T, Ekuadzi E, Komlaga G.

Afr J Tradit Complement Altern Med. 2011 Dec 29;9(2):271-6. eCollection 2012.

39.

EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery.

Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT.

J Thorac Oncol. 2011 May;6(5):947-50. doi: 10.1097/JTO.0b013e31820db209.

40.

Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer.

Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V.

Mol Oncol. 2011 Feb;5(1):61-76. doi: 10.1016/j.molonc.2010.11.004. Epub 2010 Nov 25.

41.

Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt).

Lockman JW, Murphy BR, Zigar DF, Judd WR, Slattum PM, Gao ZH, Ostanin K, Green J, McKinnon R, Terry-Lorenzo RT, Fleischer TC, Boniface JJ, Shenderovich M, Willardsen JA.

J Med Chem. 2010 Dec 23;53(24):8734-46. doi: 10.1021/jm101145b. Epub 2010 Nov 16.

PMID:
21080724
42.

Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound.

Fleischer TC, Murphy BR, Flick JS, Terry-Lorenzo RT, Gao ZH, Davis T, McKinnon R, Ostanin K, Willardsen JA, Boniface JJ.

Chem Biol. 2010 Jun 25;17(6):659-64. doi: 10.1016/j.chembiol.2010.05.008.

43.

Will escalating spending on HIV treatment displace funding for treatment of other diseases?

Fleischer T, Kevany S, Benatar SR.

S Afr Med J. 2010 Jan;100(1):32-4. No abstract available.

PMID:
20429484
44.

Assesssing herbal medical practitioners in professional qualifying examination in Ghana, a model.

Adusi-Poku Y, Okine LK, Hlortsi-Akakpo FK, Fleischer TC, Mensah ML, Arhin P, Agyemfra G, Dabra T, Mensah EN.

Afr J Tradit Complement Altern Med. 2009 Oct 15;7(1):85-7.

45.

Contacting the brain--aspects of a technology assessment of neural implants.

Decker M, Fleischer T.

Biotechnol J. 2008 Dec;3(12):1502-10. doi: 10.1002/biot.200800225.

PMID:
19072906
46.

Antimicrobial activity of essential oils of Xylopia aethiopica.

Fleischer TC, Mensah ML, Mensah AY, Komlaga G, Gbedema SY, Skaltsa H.

Afr J Tradit Complement Altern Med. 2008 Jun 18;5(4):391-3.

47.

Effectiveness and safety assessment of Mist Tonica, a herbal haematinic.

Adusi-Poku Y, Sittie A, Mensah ML, Sarpong K, Fleischer TC, Ankrah TC, Nsiah D.

Afr J Tradit Complement Altern Med. 2008 Jan 22;5(2):115-9.

48.

Ethical issues in research in low-income countries.

Benatar SR, Fleischer TE.

Int J Tuberc Lung Dis. 2007 Jun;11(6):617-23.

PMID:
17519092
49.

Enrolling adolescents in HIV vaccine trials: reflections on legal complexities from South Africa.

Slack C, Strode A, Fleischer T, Gray G, Ranchod C.

BMC Med Ethics. 2007 May 13;8:5.

50.

Bioethics with blinders.

Benatar S, Fleischer T.

Hastings Cent Rep. 2006 Sep-Oct;36(5):4; author reply 4-5. No abstract available.

PMID:
17091686

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