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Items: 32


Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16- Monocytes.

Lee MKS, Al-Sharea A, Shihata WA, Bertuzzo Veiga C, Cooney OD, Fleetwood AJ, Flynn MC, Claeson E, Palmer CS, Lancaster GI, Henstridge DC, Hamilton JA, Murphy AJ.

Front Immunol. 2019 Sep 6;10:2054. doi: 10.3389/fimmu.2019.02054. eCollection 2019.


Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages.

De Souza DP, Achuthan A, Lee MK, Binger KJ, Lee MC, Davidson S, Tull DL, McConville MJ, Cook AD, Murphy AJ, Hamilton JA, Fleetwood AJ.

J Clin Invest. 2019 Oct 1;129(10):4239-4244. doi: 10.1172/JCI127597.


GM-CSF- and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage Phenotype during Inflammation.

Lee MC, Lacey DC, Fleetwood AJ, Achuthan A, Hamilton JA, Cook AD.

J Immunol. 2019 May 15;202(10):3033-3040. doi: 10.4049/jimmunol.1801549. Epub 2019 Apr 15.


CSF-1 in Inflammatory and Arthritic Pain Development.

Saleh R, Lee MC, Khiew SH, Louis C, Fleetwood AJ, Achuthan A, Förster I, Cook AD, Hamilton JA.

J Immunol. 2018 Oct 1;201(7):2042-2053. doi: 10.4049/jimmunol.1800665. Epub 2018 Aug 17.


Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages.

Hsu AT, Lupancu TJ, Lee MC, Fleetwood AJ, Cook AD, Hamilton JA, Achuthan A.

J Biol Chem. 2018 Jul 20;293(29):11415-11423. doi: 10.1074/jbc.RA118.002416. Epub 2018 Jun 5.


Cytokine-Induced Acute Inflammatory Monoarticular Arthritis.

Achuthan A, Lee MC, Saleh R, Fleetwood AJ, Hamilton JA, Cook AD.

Methods Mol Biol. 2018;1784:215-223. doi: 10.1007/978-1-4939-7837-3_20.


CCL17 blockade as a therapy for osteoarthritis pain and disease.

Lee MC, Saleh R, Achuthan A, Fleetwood AJ, Förster I, Hamilton JA, Cook AD.

Arthritis Res Ther. 2018 Apr 5;20(1):62. doi: 10.1186/s13075-018-1560-9.


TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.

Cook AD, Lee MC, Saleh R, Khiew HW, Christensen AD, Achuthan A, Fleetwood AJ, Lacey DC, Smith JE, Förster I, Hamilton JA.

JCI Insight. 2018 Mar 22;3(6). pii: 99249. doi: 10.1172/jci.insight.99249.


Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity.

Achuthan A, Aslam ASM, Nguyen Q, Lam PY, Fleetwood AJ, Frye AT, Louis C, Lee MC, Smith JE, Cook AD, Olshansky M, Turner SJ, Hamilton JA.

Cell Death Dis. 2018 Feb 15;9(3):267. doi: 10.1038/s41419-018-0332-4.


Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O'Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA.

Front Cell Infect Microbiol. 2017 Aug 4;7:351. doi: 10.3389/fcimb.2017.00351. eCollection 2017.


G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.

Lee MC, McCubbin JA, Christensen AD, Poole DP, Rajasekhar P, Lieu T, Bunnett NW, Garcia-Caraballo S, Erickson A, Brierley SM, Saleh R, Achuthan A, Fleetwood AJ, Anderson RL, Hamilton JA, Cook AD.

J Immunol. 2017 May 1;198(9):3565-3575. doi: 10.4049/jimmunol.1602127. Epub 2017 Mar 20.


Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.

Achuthan A, Cook AD, Lee MC, Saleh R, Khiew HW, Chang MW, Louis C, Fleetwood AJ, Lacey DC, Christensen AD, Frye AT, Lam PY, Kusano H, Nomura K, Steiner N, Förster I, Nutt SL, Olshansky M, Turner SJ, Hamilton JA.

J Clin Invest. 2016 Sep 1;126(9):3453-66. doi: 10.1172/JCI87828. Epub 2016 Aug 15.


OSCAR-collagen signaling in monocytes plays a proinflammatory role and may contribute to the pathogenesis of rheumatoid arthritis.

Schultz HS, Guo L, Keller P, Fleetwood AJ, Sun M, Guo W, Ma C, Hamilton JA, Bjørkdahl O, Berchtold MW, Panina S.

Eur J Immunol. 2016 Apr;46(4):952-63. doi: 10.1002/eji.201545986. Epub 2016 Feb 9.


Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System.

Louis C, Cook AD, Lacey D, Fleetwood AJ, Vlahos R, Anderson GP, Hamilton JA.

J Immunol. 2015 Jul 1;195(1):134-44. doi: 10.4049/jimmunol.1500369. Epub 2015 May 27.


Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS.

Fleetwood AJ, O'Brien-Simpson NM, Veith PD, Lam RS, Achuthan A, Cook AD, Singleton W, Lund IK, Reynolds EC, Hamilton JA.

J Biol Chem. 2015 Jun 26;290(26):16031-42. doi: 10.1074/jbc.M115.645572. Epub 2015 May 15.


GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar bone loss in a mouse periodontitis model.

Lam RS, O'Brien-Simpson NM, Hamilton JA, Lenzo JC, Holden JA, Brammar GC, Orth RK, Tan Y, Walsh KA, Fleetwood AJ, Reynolds EC.

Immunol Cell Biol. 2015 Sep;93(8):705-15. doi: 10.1038/icb.2015.25. Epub 2015 Mar 10.


Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor.

Schultz HS, Nitze LM, Zeuthen LH, Keller P, Gruhler A, Pass J, Chen J, Guo L, Fleetwood AJ, Hamilton JA, Berchtold MW, Panina S.

J Immunol. 2015 Apr 1;194(7):3169-79. doi: 10.4049/jimmunol.1402800. Epub 2015 Feb 27.


Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1.

Read CB, Kuijper JL, Hjorth SA, Heipel MD, Tang X, Fleetwood AJ, Dantzler JL, Grell SN, Kastrup J, Wang C, Brandt CS, Hansen AJ, Wagtmann NR, Xu W, Stennicke VW.

J Immunol. 2015 Feb 15;194(4):1417-21. doi: 10.4049/jimmunol.1402303. Epub 2015 Jan 16.


Urokinase plasminogen activator is a central regulator of macrophage three-dimensional invasion, matrix degradation, and adhesion.

Fleetwood AJ, Achuthan A, Schultz H, Nansen A, Almholt K, Usher P, Hamilton JA.

J Immunol. 2014 Apr 15;192(8):3540-7. doi: 10.4049/jimmunol.1302864. Epub 2014 Mar 10.


Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models.

Lacey DC, Achuthan A, Fleetwood AJ, Dinh H, Roiniotis J, Scholz GM, Chang MW, Beckman SK, Cook AD, Hamilton JA.

J Immunol. 2012 Jun 1;188(11):5752-65. doi: 10.4049/jimmunol.1103426. Epub 2012 Apr 30.


GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

Fleetwood AJ, Dinh H, Cook AD, Hertzog PJ, Hamilton JA.

J Leukoc Biol. 2009 Aug;86(2):411-21. doi: 10.1189/jlb.1108702. Epub 2009 Apr 30. Erratum in: J Leukoc Biol. 2012 Feb;91(2):347. J Leukoc Biol. 2012 Feb;91(2):347.


Macrophage lineage phenotypes and osteoclastogenesis--complexity in the control by GM-CSF and TGF-beta.

Lari R, Fleetwood AJ, Kitchener PD, Cook AD, Pavasovic D, Hertzog PJ, Hamilton JA.

Bone. 2007 Feb;40(2):323-36. Epub 2006 Oct 18.


Functions of granulocyte-macrophage colony-stimulating factor.

Fleetwood AJ, Cook AD, Hamilton JA.

Crit Rev Immunol. 2005;25(5):405-28. Review.


A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

De Nardo D, Masendycz P, Ho S, Cross M, Fleetwood AJ, Reynolds EC, Hamilton JA, Scholz GM.

J Biol Chem. 2005 Mar 18;280(11):9813-22. Epub 2005 Jan 12.


Effect of rendering procedures on the scrapie agent.

Taylor DM, Woodgate SL, Fleetwood AJ, Cawthorne RJ.

Vet Rec. 1997 Dec 20-27;141(25):643-9.


Cryptosporidiosis and farm visits.

Pritchard GC, Fleetwood AJ.

Vet Rec. 1995 Feb 18;136(7):179. No abstract available.


Sodium monochloroacetate poisoning of greenfinches.

Quick MP, Porter S, Bennett AC, Fleetwood AJ.

Forensic Sci Int. 1992 Apr;54(1):1-8.


Cardiomyopathy in adult Holstein Friesian cattle in Britain.

Black DH, Robinson TC, Bradley R, Wijeratne WV, Fleetwood AJ.

Vet Rec. 1991 Nov 9;129(19):435. No abstract available.


Spongiform encephalopathy in an eland.

Fleetwood AJ, Furley CW.

Vet Rec. 1990 Apr 21;126(16):408-9. No abstract available.


Winter dysentery in adult dairy cattle.

Fleetwood AJ, Edwards S, Foxell PW, Thorns CJ.

Vet Rec. 1989 Nov 25;125(22):553-4. No abstract available.


Tuberculosis in deer.

Fleetwood AJ, Stuart FA, Bodé R, Sutton JP.

Vet Rec. 1988 Sep 3;123(10):279-80. No abstract available.


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