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Items: 47

1.

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy.

Andrejeva G, Gowan S, Lin G, Wong Te Fong AL, Shamsaei E, Parkes HG, Mui J, Raynaud FI, Asad Y, Vizcay-Barrena G, Nikitorowicz-Buniak J, Valenti M, Howell L, Fleck RA, Martin LA, Kirkin V, Leach MO, Chung YL.

Autophagy. 2019 Sep 13:1-17. doi: 10.1080/15548627.2019.1659608. [Epub ahead of print]

PMID:
31517566
2.

Human mesenchymal stromal cells engineered to express collagen VII can restore anchoring fibrils in recessive dystrophic epidermolysis bullosa skin graft chimeras.

Petrova A, Georgiadis C, Fleck RA, Allison L, McGrath JA, Dazzi F, Di WL, Qasim W.

J Invest Dermatol. 2019 Jul 18. pii: S0022-202X(19)32535-7. doi: 10.1016/j.jid.2019.05.031. [Epub ahead of print]

PMID:
31326396
3.

Detailed hair shaft analysis in a man with delayed-onset Chediak-Higashi syndrome.

Veraitch O, Allison L, Vizcay-Barrena G, Fleck RA, Price A, Fenton DA, McGrath JA, Stefanato CM.

Br J Dermatol. 2019 Jul 13. doi: 10.1111/bjd.18341. [Epub ahead of print] No abstract available.

PMID:
31301233
4.

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3.

Borghesan M, Fafián-Labora J, Eleftheriadou O, Carpintero-Fernández P, Paez-Ribes M, Vizcay-Barrena G, Swisa A, Kolodkin-Gal D, Ximénez-Embún P, Lowe R, Martín-Martín B, Peinado H, Muñoz J, Fleck RA, Dor Y, Ben-Porath I, Vossenkamper A, Muñoz-Espin D, O'Loghlen A.

Cell Rep. 2019 Jun 25;27(13):3956-3971.e6. doi: 10.1016/j.celrep.2019.05.095.

5.

Application of PLGA/FGF-2 coaxial microfibers in spinal cord tissue engineering: an in vitro and in vivo investigation.

Reis KP, Sperling LE, Teixeira C, Paim Á, Alcântara B, Vizcay-Barrena G, Fleck RA, Pranke P.

Regen Med. 2018 Oct;13(7):785-801. doi: 10.2217/rme-2018-0060. Epub 2018 Oct 5.

PMID:
30289057
6.

A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration.

Grillo FW, Neves G, Walker A, Vizcay-Barrena G, Fleck RA, Branco T, Burrone J.

Neuron. 2018 Jul 25;99(2):275-282.e3. doi: 10.1016/j.neuron.2018.06.015. Epub 2018 Jul 5.

7.

Cellular dissection of malaria parasite invasion of human erythrocytes using viable Plasmodium knowlesi merozoites.

Lyth O, Vizcay-Barrena G, Wright KE, Haase S, Mohring F, Najer A, Henshall IG, Ashdown GW, Bannister LH, Drew DR, Beeson JG, Fleck RA, Moon RW, Wilson DW, Baum J.

Sci Rep. 2018 Jul 5;8(1):10165. doi: 10.1038/s41598-018-28457-z.

8.

Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons.

Hervera A, De Virgiliis F, Palmisano I, Zhou L, Tantardini E, Kong G, Hutson T, Danzi MC, Perry RB, Santos CXC, Kapustin AN, Fleck RA, Del Río JA, Carroll T, Lemmon V, Bixby JL, Shah AM, Fainzilber M, Di Giovanni S.

Nat Cell Biol. 2018 Sep;20(9):1098. doi: 10.1038/s41556-018-0063-x.

PMID:
29520084
9.

Publisher Correction: A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.

Thomas JA, Tan MSY, Bisson C, Borg A, Umrekar TR, Hackett F, Hale VL, Vizcay-Barrena G, Fleck RA, Snijders AP, Saibil HR, Blackman MJ.

Nat Microbiol. 2018 Apr;3(4):523. doi: 10.1038/s41564-018-0134-6.

PMID:
29511275
10.

A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.

Thomas JA, Tan MSY, Bisson C, Borg A, Umrekar TR, Hackett F, Hale VL, Vizcay-Barrena G, Fleck RA, Snijders AP, Saibil HR, Blackman MJ.

Nat Microbiol. 2018 Apr;3(4):447-455. doi: 10.1038/s41564-018-0111-0. Epub 2018 Feb 19. Erratum in: Nat Microbiol. 2018 Mar 6;:.

11.

3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection.

Ortega-Prieto AM, Skelton JK, Wai SN, Large E, Lussignol M, Vizcay-Barrena G, Hughes D, Fleck RA, Thursz M, Catanese MT, Dorner M.

Nat Commun. 2018 Feb 14;9(1):682. doi: 10.1038/s41467-018-02969-8.

12.

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons.

Hervera A, De Virgiliis F, Palmisano I, Zhou L, Tantardini E, Kong G, Hutson T, Danzi MC, Perry RB, Santos CXC, Kapustin AN, Fleck RA, Del Río JA, Carroll T, Lemmon V, Bixby JL, Shah AM, Fainzilber M, Di Giovanni S.

Nat Cell Biol. 2018 Mar;20(3):307-319. doi: 10.1038/s41556-018-0039-x. Epub 2018 Feb 12. Erratum in: Nat Cell Biol. 2018 Mar 8;:.

PMID:
29434374
13.

Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration.

Baron O, Boudi A, Dias C, Schilling M, Nölle A, Vizcay-Barrena G, Rattray I, Jungbluth H, Scheper W, Fleck RA, Bates GP, Fanto M.

Curr Biol. 2017 Dec 4;27(23):3626-3642.e6. doi: 10.1016/j.cub.2017.10.054. Epub 2017 Nov 22.

14.

A Moving Source of Matrix Components Is Essential for De Novo Basement Membrane Formation.

Matsubayashi Y, Louani A, Dragu A, Sánchez-Sánchez BJ, Serna-Morales E, Yolland L, Gyoergy A, Vizcay G, Fleck RA, Heddleston JM, Chew TL, Siekhaus DE, Stramer BM.

Curr Biol. 2017 Nov 20;27(22):3526-3534.e4. doi: 10.1016/j.cub.2017.10.001. Epub 2017 Nov 9.

15.

Observation of metal nanoparticles at atomic resolution in Pt-based cancer chemotherapeutics.

Sheader AA, Varambhia AM, Fleck RA, Flatters SJL, Nellist PD.

J Microsc. 2018 Apr;270(1):92-97. doi: 10.1111/jmi.12659. Epub 2017 Nov 1.

PMID:
29091266
16.

Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB).

Sekhar GN, Georgian AR, Sanderson L, Vizcay-Barrena G, Brown RC, Muresan P, Fleck RA, Thomas SA.

PLoS One. 2017 Mar 31;12(3):e0173474. doi: 10.1371/journal.pone.0173474. eCollection 2017.

17.

Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress.

Hale VL, Watermeyer JM, Hackett F, Vizcay-Barrena G, van Ooij C, Thomas JA, Spink MC, Harkiolaki M, Duke E, Fleck RA, Blackman MJ, Saibil HR.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3439-3444. doi: 10.1073/pnas.1619441114. Epub 2017 Mar 14.

18.

TatA complexes exhibit a marked change in organisation in response to expression of the TatBC complex.

Smith SM, Yarwood A, Fleck RA, Robinson C, Smith CJ.

Biochem J. 2017 Apr 19;474(9):1495-1508. doi: 10.1042/BCJ20160952.

19.

Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites.

Walker AS, Neves G, Grillo F, Jackson RE, Rigby M, O'Donnell C, Lowe AS, Vizcay-Barrena G, Fleck RA, Burrone J.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1986-E1995. doi: 10.1073/pnas.1607462114. Epub 2017 Feb 16.

20.

Tunable Ultra-high Aspect Ratio Nanorod Architectures grown on Porous Substrate via Electromigration.

Mansourian A, Paknejad SA, Wen Q, Vizcay-Barrena G, Fleck RA, Zayats AV, Mannan SH.

Sci Rep. 2016 Feb 29;6:22272. doi: 10.1038/srep22272.

21.

Hair Follicle Miniaturization in a Woolly Hair Nevus: A Novel "Root" Perspective for a Mosaic Hair Disorder.

Veraitch O, Perez A, Hoque SR, Vizcay-Barrena G, Fleck RA, Fenton DA, Stefanato CM.

Am J Dermatopathol. 2016 Mar;38(3):239-43. doi: 10.1097/DAD.0000000000000525.

PMID:
26894777
22.

Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis.

Lussignol M, Kopp M, Molloy K, Vizcay-Barrena G, Fleck RA, Dorner M, Bell KL, Chait BT, Rice CM, Catanese MT.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2484-9. doi: 10.1073/pnas.1518934113. Epub 2016 Feb 16.

23.

Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.

Buniello A, Ingham NJ, Lewis MA, Huma AC, Martinez-Vega R, Varela-Nieto I, Vizcay-Barrena G, Fleck RA, Houston O, Bardhan T, Johnson SL, White JK, Yuan H, Marcotti W, Steel KP.

EMBO Mol Med. 2016 Mar 1;8(3):191-207. doi: 10.15252/emmm.201505523.

24.

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

Georgiadis C, Syed F, Petrova A, Abdul-Wahab A, Lwin SM, Farzaneh F, Chan L, Ghani S, Fleck RA, Glover L, McMillan JR, Chen M, Thrasher AJ, McGrath JA, Di WL, Qasim W.

J Invest Dermatol. 2016 Jan;136(1):284-92. doi: 10.1038/JID.2015.364.

25.

A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes.

Watermeyer JM, Hale VL, Hackett F, Clare DK, Cutts EE, Vakonakis I, Fleck RA, Blackman MJ, Saibil HR.

Blood. 2016 Jan 21;127(3):343-51. doi: 10.1182/blood-2015-10-674002. Epub 2015 Dec 4.

26.

Lentiviral Engineered Fibroblasts Expressing Codon Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

Georgiadis C, Syed F, Petrova A, Abdul-Wahab A, Lwin SM, Farzaneh F, Chan L, Ghani S, Fleck RA, Glover L, McMillan JR, Chen M, Thrasher AJ, McGrath JA, Di WL, Qasim W.

J Invest Dermatol. 2015 Sep 22. doi: 10.1038/jid.2015.364. [Epub ahead of print]

PMID:
26394110
27.

Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy.

Bullen A, West T, Moores C, Ashmore J, Fleck RA, MacLellan-Gibson K, Forge A.

J Cell Sci. 2015 Jul 15;128(14):2529-40. doi: 10.1242/jcs.170761. Epub 2015 Jun 4.

28.

Low-temperature electron microscopy: techniques and protocols.

Fleck RA.

Methods Mol Biol. 2015;1257:243-74. doi: 10.1007/978-1-4939-2193-5_9.

PMID:
25428009
29.

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome.

Costa A, Renault L, Swuec P, Petojevic T, Pesavento JJ, Ilves I, MacLellan-Gibson K, Fleck RA, Botchan MR, Berger JM.

Elife. 2014 Aug 12;3:e03273. doi: 10.7554/eLife.03273.

30.

Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods.

Bullen A, Taylor RR, Kachar B, Moores C, Fleck RA, Forge A.

Hear Res. 2014 Sep;315:49-60. doi: 10.1016/j.heares.2014.06.006. Epub 2014 Jul 10.

31.

The effect of sterilization methods on electronspun poly(lactide-co-glycolide) and subsequent adhesion efficiency of mesenchymal stem cells.

Braghirolli DI, Steffens D, Quintiliano K, Acasigua GA, Gamba D, Fleck RA, Petzhold CL, Pranke P.

J Biomed Mater Res B Appl Biomater. 2014 May;102(4):700-8. doi: 10.1002/jbm.b.33049. Epub 2013 Nov 21.

PMID:
24259451
32.

Confocal microscopy study of pertussis toxin and toxoids on CHO-cells.

Tan Y, Fleck RA, Asokanathan C, Yuen CT, Xing D, Zhang S, Wang J.

Hum Vaccin Immunother. 2013 Feb;9(2):332-8. Epub 2013 Jan 4.

33.

Maturational alterations in gap junction expression and associated collagen synthesis in response to tendon function.

Young NJ, Becker DL, Fleck RA, Goodship AE, Patterson-Kane JC.

Matrix Biol. 2009 Jul;28(6):311-23. doi: 10.1016/j.matbio.2009.05.002. Epub 2009 May 27.

PMID:
19481603
34.

A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodies.

Uria MJ, Zhang Q, Li Y, Chan A, Exley RM, Gollan B, Chan H, Feavers I, Yarwood A, Abad R, Borrow R, Fleck RA, Mulloy B, Vazquez JA, Tang CM.

J Exp Med. 2008 Jun 9;205(6):1423-34. doi: 10.1084/jem.20072577. Epub 2008 May 26.

35.

Gap junction protein expression and cellularity: comparison of immature and adult equine digital tendons.

Stanley RL, Fleck RA, Becker DL, Goodship AE, Ralphs JR, Patterson-Kane JC.

J Anat. 2007 Sep;211(3):325-34.

36.

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

International Stem Cell Initiative, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, Hovatta O, Hyllner J, Imreh MP, Itskovitz-Eldor J, Jackson J, Johnson JL, Jones M, Kee K, King BL, Knowles BB, Lako M, Lebrin F, Mallon BS, Manning D, Mayshar Y, McKay RD, Michalska AE, Mikkola M, Mileikovsky M, Minger SL, Moore HD, Mummery CL, Nagy A, Nakatsuji N, O'Brien CM, Oh SK, Olsson C, Otonkoski T, Park KY, Passier R, Patel H, Patel M, Pedersen R, Pera MF, Piekarczyk MS, Pera RA, Reubinoff BE, Robins AJ, Rossant J, Rugg-Gunn P, Schulz TC, Semb H, Sherrer ES, Siemen H, Stacey GN, Stojkovic M, Suemori H, Szatkiewicz J, Turetsky T, Tuuri T, van den Brink S, Vintersten K, Vuoristo S, Ward D, Weaver TA, Young LA, Zhang W.

Nat Biotechnol. 2007 Jul;25(7):803-16. Epub 2007 Jun 17.

PMID:
17572666
37.

Impact of antifreeze proteins and antifreeze glycoproteins on bovine sperm during freeze-thaw.

Prathalingam NS, Holt WV, Revell SG, Mirczuk S, Fleck RA, Watson PF.

Theriogenology. 2006 Nov;66(8):1894-900. Epub 2006 Jun 13.

PMID:
16777208
38.

Evaluation of adenyl cyclase toxin constructs from Bordetella pertussis as candidate vaccine components in an in vitro model of complement-dependent intraphagocytic killing.

Prior S, Fleck RA, Gillett ML, Rigsby PR, Corbel MJ, Stacey GN, Xing DK.

Vaccine. 2006 May 29;24(22):4794-803. Epub 2006 Apr 3.

PMID:
16675078
39.

Use of opsonophagocytosis for serological evaluation of pneumococcal vaccines.

Romero-Steiner S, Frasch CE, Carlone G, Fleck RA, Goldblatt D, Nahm MH.

Clin Vaccine Immunol. 2006 Feb;13(2):165-9. Review. No abstract available.

40.

Characterisation of cryoinjury in Euglena gracilis using flow-cytometry and cryomicroscopy.

Fleck RA, Pickup RW, Day JG, Benson EE.

Cryobiology. 2006 Apr;52(2):261-8. Epub 2006 Feb 7.

PMID:
16455069
41.

Use of HL-60 cell line to measure opsonic capacity of pneumococcal antibodies.

Fleck RA, Romero-Steiner S, Nahm MH.

Clin Diagn Lab Immunol. 2005 Jan;12(1):19-27. Review. No abstract available.

42.

A comparative study of antioxidant protection in cryopreserved unicellular algae Euglena gracilis and Haematococcus pluvialis.

Fleck RA, Benson EE, Bremner DH, Day JG.

Cryo Letters. 2003 Jul-Aug;24(4):213-28.

PMID:
12955169
43.

Optimization of nb-4 and hl-60 differentiation for use in opsonophagocytosis assays.

Fleck RA, Athwal H, Bygraves JA, Hockley DJ, Feavers IM, Stacey GN.

In Vitro Cell Dev Biol Anim. 2003 May-Jun;39(5-6):235-42.

PMID:
12873158
45.
46.

Properties of factor VIIa/tissue factor complexes in an umbilical vein model.

Almus FE, Rao LV, Fleck RA, Rapaport SI.

Blood. 1990 Jul 15;76(2):354-60.

47.

Anti-prothrombin antibodies and the lupus anticoagulant.

Fleck RA, Rapaport SI, Rao LV.

Blood. 1988 Aug;72(2):512-9.

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