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Items: 1 to 50 of 79

1.

Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei.

Schlesinger M, Vilchez Larrea SC, Haikarainen T, Narwal M, Venkannagari H, Flawiá MM, Lehtiö L, Fernández Villamil SH.

Parasit Vectors. 2016 Mar 23;9:173. doi: 10.1186/s13071-016-1461-1.

2.

Selective pressure against horizontally acquired prokaryotic genes as a driving force of plastid evolution.

Llorente B, de Souza FSJ, Soto G, Meyer C, Alonso GD, Flawiá MM, Bravo-Almonacid F, Ayub ND, Rodríguez-Concepción M.

Sci Rep. 2016 Jan 11;6:19036. doi: 10.1038/srep19036.

3.

Phosphatidylinositol kinase activities in Trypanosoma cruzi epimastigotes.

Gimenez AM, Gesumaría MC, Schoijet AC, Alonso GD, Flawiá MM, Racagni GE, Machado EE.

Mol Biochem Parasitol. 2015 Sep-Oct;203(1-2):14-24. doi: 10.1016/j.molbiopara.2015.10.002. Epub 2015 Oct 19.

PMID:
26493613
4.

Host cell poly(ADP-ribose) glycohydrolase is crucial for Trypanosoma cruzi infection cycle.

Vilchez Larrea SC, Schlesinger M, Kevorkian ML, Flawiá MM, Alonso GD, Fernández Villamil SH.

PLoS One. 2013 Jun 12;8(6):e67356. doi: 10.1371/journal.pone.0067356. Print 2013.

5.

Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite.

Vilchez Larrea SC, Haikarainen T, Narwal M, Schlesinger M, Venkannagari H, Flawiá MM, Villamil SH, Lehtiö L.

PLoS One. 2012;7(9):e46063. doi: 10.1371/journal.pone.0046063. Epub 2012 Sep 25.

6.

Poly(ADP-ribose) polymerase plays a differential role in DNA damage-response and cell death pathways in Trypanosoma cruzi.

Vilchez Larrea SC, Alonso GD, Schlesinger M, Torres HN, Flawiá MM, Fernández Villamil SH.

Int J Parasitol. 2011 Mar;41(3-4):405-16. doi: 10.1016/j.ijpara.2010.11.008. Epub 2010 Dec 23.

PMID:
21185298
7.

Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi.

Schoijet AC, Miranda K, Medeiros LC, de Souza W, Flawiá MM, Torres HN, Pignataro OP, Docampo R, Alonso GD.

Mol Microbiol. 2011 Jan;79(1):50-62. doi: 10.1111/j.1365-2958.2010.07429.x. Epub 2010 Oct 28.

8.

Improvement of aroma in transgenic potato as a consequence of impairing tuber browning.

Llorente B, Rodríguez V, Alonso GD, Torres HN, Flawiá MM, Bravo-Almonacid FF.

PLoS One. 2010 Nov 17;5(11):e14030. doi: 10.1371/journal.pone.0014030.

9.

A quantitative real-time PCR method for in planta monitoring of Phytophthora infestans growth.

Llorente B, Bravo-Almonacid F, Cvitanich C, Orlowska E, Torres HN, Flawiá MM, Alonso GD.

Lett Appl Microbiol. 2010 Dec;51(6):603-10. doi: 10.1111/j.1472-765X.2010.02942.x. Epub 2010 Oct 11.

10.

The NADPH-cytochrome P450 reductase family in Trypanosoma cruzi is involved in the sterol biosynthesis pathway.

De Vas MG, Portal P, Alonso GD, Schlesinger M, Flawiá MM, Torres HN, Fernández Villamil S, Paveto C.

Int J Parasitol. 2011 Jan;41(1):99-108. doi: 10.1016/j.ijpara.2010.07.016. Epub 2010 Sep 16.

PMID:
20849858
11.

Safety assessment of nonbrowning potatoes: opening the discussion about the relevance of substantial equivalence on next generation biotech crops.

Llorente B, Alonso GD, Bravo-Almonacid F, Rodríguez V, López MG, Carrari F, Torres HN, Flawiá MM.

Plant Biotechnol J. 2011 Feb;9(2):136-50. doi: 10.1111/j.1467-7652.2010.00534.x.

12.

A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis.

Schoijet AC, Miranda K, Girard-Dias W, de Souza W, Flawiá MM, Torres HN, Docampo R, Alonso GD.

J Biol Chem. 2008 Nov 14;283(46):31541-50. doi: 10.1074/jbc.M801367200. Epub 2008 Sep 17.

13.

Multiple NADPH-cytochrome P450 reductases from Trypanosoma cruzi suggested role on drug resistance.

Portal P, Fernández Villamil S, Alonso GD, De Vas MG, Flawiá MM, Torres HN, Paveto C.

Mol Biochem Parasitol. 2008 Jul;160(1):42-51. doi: 10.1016/j.molbiopara.2008.03.007. Epub 2008 Mar 21.

PMID:
18455247
14.

TcPARP: A DNA damage-dependent poly(ADP-ribose) polymerase from Trypanosoma cruzi.

Fernández Villamil SH, Baltanás R, Alonso GD, Vilchez Larrea SC, Torres HN, Flawiá MM.

Int J Parasitol. 2008 Mar;38(3-4):277-87. Epub 2007 Sep 8.

PMID:
17936287
15.

Trypanosoma cruzi: in vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg).

Güida MC, Esteva MI, Camino A, Flawiá MM, Torres HN, Paveto C.

Exp Parasitol. 2007 Oct;117(2):188-94. Epub 2007 May 16.

PMID:
17673202
16.

TcrPDEA1, a cAMP-specific phosphodiesterase with atypical pharmacological properties from Trypanosoma cruzi.

Alonso GD, Schoijet AC, Torres HN, Flawiá MM.

Mol Biochem Parasitol. 2007 Mar;152(1):72-9. Epub 2006 Dec 29.

PMID:
17222469
17.

Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: a unified nomenclature.

Kunz S, Beavo JA, D'Angelo MA, Flawia MM, Francis SH, Johner A, Laxman S, Oberholzer M, Rascon A, Shakur Y, Wentzinger L, Zoraghi R, Seebeck T.

Mol Biochem Parasitol. 2006 Jan;145(1):133-5. Epub 2005 Oct 21. No abstract available.

PMID:
16280178
18.

TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi.

Alonso GD, Schoijet AC, Torres HN, Flawiá MM.

Mol Biochem Parasitol. 2006 Jan;145(1):40-9. Epub 2005 Sep 30.

PMID:
16225937
19.

Anti-Trypanosoma cruzi activity of green tea (Camellia sinensis) catechins.

Paveto C, Güida MC, Esteva MI, Martino V, Coussio J, Flawiá MM, Torres HN.

Antimicrob Agents Chemother. 2004 Jan;48(1):69-74.

20.

Arginine kinase overexpression improves Trypanosoma cruzi survival capability.

Pereira CA, Alonso GD, Ivaldi S, Silber AM, Alves MJ, Torres HN, Flawiá MM.

FEBS Lett. 2003 Nov 6;554(1-2):201-5.

21.

Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.

D'Angelo MA, Sanguineti S, Reece JM, Birnbaumer L, Torres HN, Flawiá MM.

Biochem J. 2004 Feb 15;378(Pt 1):63-72.

22.

Trypanosoma cruzi poly-zinc finger protein: a novel DNA/RNA-binding CCHC-zinc finger protein.

Espinosa JM, Portal D, Lobo GS, Pereira CA, Alonso GD, Gómez EB, Lan GH, Pomar RV, Flawiá MM, Torres HN.

Mol Biochem Parasitol. 2003 Sep;131(1):35-44.

PMID:
12967710
23.

Screening of substrate analogs as potential enzyme inhibitors for the arginine kinase of Trypanosoma cruzi.

Pereira CA, Alonso GD, Ivaldi S, Bouvier LA, Torres HN, Flawiá MM.

J Eukaryot Microbiol. 2003 Mar-Apr;50(2):132-4.

PMID:
12744526
24.

An early ancestor in the evolution of splicing: a Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing.

Portal D, Espinosa JM, Lobo GS, Kadener S, Pereira CA, De La Mata M, Tang Z, Lin RJ, Kornblihtt AR, Baralle FE, Flawiá MM, Torres HN.

Mol Biochem Parasitol. 2003 Mar;127(1):37-46.

PMID:
12615334
25.

Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases.

Portal D, Lobo GS, Kadener S, Prasad J, Espinosa JM, Pereira CA, Tang Z, Lin RJ, Manley JL, Kornblihtt AR, Flawiá MM, Torres HN.

Mol Biochem Parasitol. 2003 Mar;127(1):9-21.

PMID:
12615332
26.

Arginine metabolism in Trypanosoma cruzi is coupled to parasite stage and replication.

Pereira CA, Alonso GD, Ivaldi S, Silber A, Alves MJ, Bouvier LA, Flawiá MM, Torres HN.

FEBS Lett. 2002 Aug 28;526(1-3):111-4.

27.

A novel calcium-stimulated adenylyl cyclase from Trypanosoma cruzi, which interacts with the structural flagellar protein paraflagellar rod.

D'Angelo MA, Montagna AE, Sanguineti S, Torres HN, Flawiá MM.

J Biol Chem. 2002 Sep 20;277(38):35025-34. Epub 2002 Jul 16.

28.

Arginine kinase: a common feature for management of energy reserves in African and American flagellated trypanosomatids.

Pereira CA, Alonso GD, Torres HN, Flawiá MM.

J Eukaryot Microbiol. 2002 Jan-Feb;49(1):82-5.

PMID:
11908902
29.

Arginine kinase of the flagellate protozoa Trypanosoma cruzi. Regulation of its expression and catalytic activity.

Alonso GD, Pereira CA, Remedi MS, Paveto MC, Cochella L, Ivaldi MS, Gerez de Burgos NM, Torres HN, Flawiá MM.

FEBS Lett. 2001 Jun 1;498(1):22-5.

30.

Immuno and cytochemical localization of Trypanosoma cruzi nitric oxide synthase.

Goldstein J, Paveto C, López-Costa JJ, Pereira C, Alonso G, Torres HN, Flawia MM.

Biocell. 2000 Dec;24(3):217-22.

PMID:
11201657
31.

MRNA encoding a putative RNA helicase of the DEAD-box gene family is up-regulated in trypomastigotes of Trypanosoma cruzi.

Diaz Añel AM, Rossi MS, Espinosa JM, Güida C, Freitas FA, Kornblihtt AR, Zingales B, Flawia MM, Torres HN.

J Eukaryot Microbiol. 2000 Nov-Dec;47(6):555-60.

PMID:
11128707
32.

Trypanosoma cruzi arginine kinase characterization and cloning. A novel energetic pathway in protozoan parasites.

Pereira CA, Alonso GD, Paveto MC, Iribarren A, Cabanas ML, Torres HN, Flawiá MM.

J Biol Chem. 2000 Jan 14;275(2):1495-501.

33.

L-arginine uptake and L-phosphoarginine synthesis in Trypanosoma cruzi.

Pereira CA, Alonso GD, Paveto MC, Flawiá MM, Torres HN.

J Eukaryot Microbiol. 1999 Nov-Dec;46(6):566-70.

PMID:
10568030
34.

Factors from Trypanosoma cruzi interacting with AP-1 sequences.

Espinosa J, Martinetto H, Portal D, D'Angelo M, Torres HN, Flawiá MM.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):516-21.

PMID:
10519220
35.

Partial characterization of guanylyl cyclase activity in calf thyroid.

Bocanera LV, Martinetto H, Flawiá MM, Pisarev MA.

Endocr Res. 1999 May;25(2):215-28.

PMID:
10382683
36.

Entamoeba histolytica: signaling through G proteins.

Paveto C, Torres HN, Flawia MM, García-Espitia M, Ortega A, Orozco E.

Exp Parasitol. 1999 Feb;91(2):170-5.

PMID:
9990345
37.

Control of Trypanosoma cruzi epimastigote motility through the nitric oxide pathway.

Pereira C, Paveto C, Espinosa J, Alonso G, Flawiá MM, Torres HN.

J Eukaryot Microbiol. 1997 Mar-Apr;44(2):155-6.

PMID:
9109262
38.

Signal transduction mechanisms in Trypanosoma cruzi.

Flawiá MM, Téllez-Iñón MT, Torres HN.

Parasitol Today. 1997 Jan;13(1):30-3.

PMID:
15275164
39.

Induction of Trypanosoma cruzi metacyclogenesis in the gut of the hematophagous insect vector, Rhodnius prolixus, by hemoglobin and peptides carrying alpha D-globin sequences.

Garcia ES, Gonzalez MS, de Azambuja P, Baralle FE, Fraidenraich D, Torres HN, Flawiá MM.

Exp Parasitol. 1995 Nov;81(3):255-61.

PMID:
7498422
40.

The nitric oxide transduction pathway in Trypanosoma cruzi.

Paveto C, Pereira C, Espinosa J, Montagna AE, Farber M, Esteva M, Flawiá MM, Torres HN.

J Biol Chem. 1995 Jul 14;270(28):16576-9.

41.

Adenylyl cyclase and G-proteins in Phytomonas.

Farber MD, Montagna AE, Paveto C, Dollet M, Sanchex-Moreno M, Osuna A, Torres HN, Flawia MM.

J Eukaryot Microbiol. 1995 May-Jun;42(3):257-60.

PMID:
12075624
42.

[Nobel Prize in medicine 1994: Martín Rodbell and Alfred Gilman. Signal transduction].

Flawia MM.

Medicina (B Aires). 1995;55(1):75-80. Spanish. No abstract available.

PMID:
7565041
43.

Stimulation of Trypanosoma cruzi adenylyl cyclase by an alpha D-globin fragment from Triatoma hindgut: effect on differentiation of epimastigote to trypomastigote forms.

Fraidenraich D, Peña C, Isola EL, Lammel EM, Coso O, Añel AD, Pongor S, Baralle F, Torres HN, Flawia MM.

Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10140-4.

44.

G-protein from Medicago sativa: functional association to photoreceptors.

Muschietti JP, Martinetto HE, Coso OA, Farber MD, Torres HN, Flawia MM.

Biochem J. 1993 Apr 15;291 ( Pt 2):383-8.

45.

Isolation of adenylate cyclase mutants from Rhizobium meliloti deficient in nodulation.

Bianchini GM, Carricarte VC, Flawia MM, Sanchez-Rivas C.

World J Microbiol Biotechnol. 1993 Mar;9(2):168-73. doi: 10.1007/BF00327829.

PMID:
24419939
46.

An alpha D-globin fragment from Triatoma infestans hindgut stimulates Trypanosoma cruzi adenylyl cyclase and promotes metacyclogenesis.

Fraidenraich D, Peña C, Isola EL, Lammel EM, Coso O, Añel AD, Baralle F, Torres HN, Flawia MM.

Biol Res. 1993;26(1-2):279-83.

PMID:
7670540
47.

Characterization of a Gi-protein from Trypanosoma cruzi epimastigote membranes.

Coso OA, Díaz Añel A, Martinetto H, Muschietti JP, Kazanietz M, Fraidenraich D, Torres HN, Flawia MM.

Biochem J. 1992 Oct 15;287 ( Pt 2):443-6.

48.

Adenylate cyclase activity in cyanobacteria: activation by Ca(2+)-calmodulin and a calmodulin-like activity.

Bianchini GM, Pastini AC, Muschietti JP, Téllez-Iñón MT, Martinetto HE, Torres HN, Flawiá MM.

Biochim Biophys Acta. 1990 Oct 15;1055(1):75-81.

PMID:
2121284
49.

Bicarbonate dependence of cAMP accumulation induced by phorbol esters in hamster spermatozoa.

Visconti PE, Muschietti JP, Flawia MM, Tezon JG.

Biochim Biophys Acta. 1990 Sep 1;1054(2):231-6.

PMID:
2169311
50.

Adaptive mechanisms of striatal D1 and D2 dopamine receptors in response to a prolonged reserpine treatment in mice.

Rubinstein M, Muschietti JP, Gershanik O, Flawia MM, Stefano FJ.

J Pharmacol Exp Ther. 1990 Feb;252(2):810-6.

PMID:
2138223

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