Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 1089

1.

hnRNPA2B1: a nuclear DNA sensor in antiviral immunity.

Zhang X, Flavell RA, Li HB.

Cell Res. 2019 Aug 30. doi: 10.1038/s41422-019-0226-8. [Epub ahead of print] No abstract available.

PMID:
31471560
2.

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Sep;573(7773):E2. doi: 10.1038/s41586-019-1490-y.

PMID:
31447485
3.

Publisher Correction: HER2 joins AKT to inhibit STING immunity.

Odell ID, Flavell RA.

Nat Cell Biol. 2019 Oct;21(10):1301. doi: 10.1038/s41556-019-0395-1.

PMID:
31444402
4.

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection.

Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, Xu H, Iijima N, Pillai PS, Kaplan DH, Weaver CT, Kluger Y, Kowalczyk MS, Iwasaki A, Pereira JP, Esplugues E, Gagliani N, Flavell RA.

Cell. 2019 Aug 22;178(5):1176-1188.e15. doi: 10.1016/j.cell.2019.07.032.

PMID:
31442406
5.

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.

Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Dela Cruz CS, Palm NW, Jackson R, Flavell RA.

Nature. 2019 Sep;573(7772):69-74. doi: 10.1038/s41586-019-1485-8. Epub 2019 Aug 21.

PMID:
31435009
6.

Publisher Correction: Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella M, Gamini R, Sécca C, Collins PL, Zhao S, Peng V, Robinette ML, Schettini J, Zaitsev K, Gordon W, Bando JK, Yomogida K, Cortez V, Fronick C, Fulton R, Lin LL, Gilfillan S, Flavell RA, Shan L, Artyomov MN, Bowman M, Oltz EM, Jelinsky SA, Colonna M.

Nat Immunol. 2019 Oct;20(10):1405. doi: 10.1038/s41590-019-0474-2.

PMID:
31388149
7.

HER2 joins AKT to inhibit STING immunity.

Odell ID, Flavell RA.

Nat Cell Biol. 2019 Aug;21(8):917-918. doi: 10.1038/s41556-019-0368-4. No abstract available. Erratum in: Nat Cell Biol. 2019 Oct;21(10):1301.

PMID:
31371829
8.

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Jul;571(7765):403-407. doi: 10.1038/s41586-019-1311-3. Epub 2019 Jun 19. Erratum in: Nature. 2019 Sep;573(7773):E2.

PMID:
31217581
9.

Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella M, Gamini R, Sécca C, Collins PL, Zhao S, Peng V, Robinette ML, Schettini J, Zaitsev K, Gordon W, Bando JK, Yomogida K, Cortez V, Fronick C, Fulton R, Lin LL, Gilfillan S, Flavell RA, Shan L, Artyomov MN, Bowman M, Oltz EM, Jelinsky SA, Colonna M.

Nat Immunol. 2019 Aug;20(8):980-991. doi: 10.1038/s41590-019-0425-y. Epub 2019 Jun 17. Erratum in: Nat Immunol. 2019 Aug 6;:.

PMID:
31209406
10.

Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis.

Tang P, Low HB, Png CW, Torta F, Kumar JK, Lim HY, Zhou Y, Yang H, Angeli V, Shabbir A, Tai ES, Flavell RA, Dong C, Wenk MR, Yang DY, Zhang Y.

Hepatol Commun. 2019 Mar 1;3(6):748-762. doi: 10.1002/hep4.1324. eCollection 2019 Jun.

11.

miR-181a/b downregulation exerts a protective action on mitochondrial disease models.

Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez-Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao-Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B.

EMBO Mol Med. 2019 May;11(5). pii: e8734. doi: 10.15252/emmm.201708734.

12.

Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis.

Barger SR, Reilly NS, Shutova MS, Li Q, Maiuri P, Heddleston JM, Mooseker MS, Flavell RA, Svitkina T, Oakes PW, Krendel M, Gauthier NC.

Nat Commun. 2019 Mar 19;10(1):1249. doi: 10.1038/s41467-019-09104-1.

13.

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.

Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS.

Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186.

14.

Role of IL-10 Receptor Signaling in the Function of CD4+ T-Regulatory Type 1 cells: T-Cell Therapy in Patients with Inflammatory Bowel Disease.

Soukou S, Brockmann L, Bedke T, Gagliani N, Flavell RA, Huber S.

Crit Rev Immunol. 2018;38(5):415-431. doi: 10.1615/CritRevImmunol.2018026850. Review.

PMID:
30806217
15.

Immunity, microbiota and kidney disease.

Knauf F, Brewer JR, Flavell RA.

Nat Rev Nephrol. 2019 May;15(5):263-274. doi: 10.1038/s41581-019-0118-7. Review.

PMID:
30796361
16.

Antiviral immunity: a link to bile acids.

Wang J, Flavell RA, Li HB.

Cell Res. 2019 Mar;29(3):177-178. doi: 10.1038/s41422-019-0148-5. No abstract available.

PMID:
30778178
17.

A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.

Song Y, Rongvaux A, Taylor A, Jiang T, Tebaldi T, Balasubramanian K, Bagale A, Terzi YK, Gbyli R, Wang X, Fu X, Gao Y, Zhao J, Podoltsev N, Xu M, Neparidze N, Wong E, Torres R, Bruscia EM, Kluger Y, Manz MG, Flavell RA, Halene S.

Nat Commun. 2019 Jan 21;10(1):366. doi: 10.1038/s41467-018-08166-x.

18.

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells.

Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi SM, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki JR, Lohse AW, Flavell RA, Krebs C, Gustafsson JA, Antonson P, Roncarolo MG, Villablanca EJ, Gagliani N, Huber S.

Nat Commun. 2018 Dec 21;9(1):5457. doi: 10.1038/s41467-018-07581-4.

19.

The translation of non-canonical open reading frames controls mucosal immunity.

Jackson R, Kroehling L, Khitun A, Bailis W, Jarret A, York AG, Khan OM, Brewer JR, Skadow MH, Duizer C, Harman CCD, Chang L, Bielecki P, Solis AG, Steach HR, Slavoff S, Flavell RA.

Nature. 2018 Dec;564(7736):434-438. doi: 10.1038/s41586-018-0794-7. Epub 2018 Dec 12.

PMID:
30542152
20.

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.

Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M.

Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8.

21.

Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells.

Ding S, Zhu S, Ren L, Feng N, Song Y, Ge X, Li B, Flavell RA, Greenberg HB.

Elife. 2018 Nov 21;7. pii: e39494. doi: 10.7554/eLife.39494.

22.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells.

Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber FJ, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell RA, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S.

J Immunol. 2018 Dec 15;201(12):3558-3568. doi: 10.4049/jimmunol.1800711. Epub 2018 Nov 16.

PMID:
30446566
23.

cGAS activation in phased droplets.

Liu Y, Li HB, Flavell RA.

Cell Res. 2018 Oct;28(10):967-968. doi: 10.1038/s41422-018-0087-6. No abstract available.

24.

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.

Tye H, Yu CH, Simms LA, de Zoete MR, Kim ML, Zakrzewski M, Penington JS, Harapas CR, Souza-Fonseca-Guimaraes F, Wockner LF, Preaudet A, Mielke LA, Wilcox SA, Ogura Y, Corr SC, Kanojia K, Kouremenos KA, De Souza DP, McConville MJ, Flavell RA, Gerlic M, Kile BT, Papenfuss AT, Putoczki TL, Radford-Smith GL, Masters SL.

Nat Commun. 2018 Sep 13;9(1):3728. doi: 10.1038/s41467-018-06125-0.

25.

Lack of Sprouty 1 and 2 enhances survival of effector CD8+ T cells and yields more protective memory cells.

Shehata HM, Khan S, Chen E, Fields PE, Flavell RA, Sanjabi S.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8939-E8947. doi: 10.1073/pnas.1808320115. Epub 2018 Aug 20.

26.

RNA m6A modification and its function in diseases.

Tong J, Flavell RA, Li HB.

Front Med. 2018 Aug;12(4):481-489. doi: 10.1007/s11684-018-0654-8. Epub 2018 Aug 10. Review.

PMID:
30097961
27.

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

Stefanski HE, Xing Y, Taylor PA, Maio S, Henao-Meija J, Williams A, Flavell RA, Hollander GA, Blazar BR.

PLoS One. 2018 Jun 27;13(6):e0198871. doi: 10.1371/journal.pone.0198871. eCollection 2018.

28.

IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN.

Diefenhardt P, Nosko A, Kluger MA, Richter JV, Wegscheid C, Kobayashi Y, Tiegs G, Huber S, Flavell RA, Stahl RAK, Steinmetz OM.

J Am Soc Nephrol. 2018 Jul;29(7):1825-1837. doi: 10.1681/ASN.2017091044. Epub 2018 Jun 4.

29.

Family-based study reveals decreased abundance of sputum Granulicatella in asthmatics.

Wang L, de Ángel Solá D, Mao Y, Bielecki P, Zhu Y, Sun Z, Shan L, Flavell RA, Bazzy-Asaad A, DeWan A.

Allergy. 2018 Sep;73(9):1918-1921. doi: 10.1111/all.13493. Epub 2018 Jun 25. No abstract available.

30.

Antigen-mediated regulation in monoclonal gammopathies and myeloma.

Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV.

JCI Insight. 2018 Apr 19;3(8). pii: 98259. doi: 10.1172/jci.insight.98259. eCollection 2018 Apr 19.

31.

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

Herndler-Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, Lietzenmayer M, Kroehling L, Takumi A, Kometani K, Inoue T, Kluger Y, Kaech SM, Kurosaki T, Okada T, Flavell RA.

Immunity. 2018 Apr 17;48(4):716-729.e8. doi: 10.1016/j.immuni.2018.03.015. Epub 2018 Apr 3.

32.

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM.

J Exp Med. 2018 Apr 2;215(4):1153-1168. doi: 10.1084/jem.20171352. Epub 2018 Feb 15.

33.

Circuit Design Features of a Stable Two-Cell System.

Zhou X, Franklin RA, Adler M, Jacox JB, Bailis W, Shyer JA, Flavell RA, Mayo A, Alon U, Medzhitov R.

Cell. 2018 Feb 8;172(4):744-757.e17. doi: 10.1016/j.cell.2018.01.015. Epub 2018 Feb 1.

34.

Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.

Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J.

J Allergy Clin Immunol. 2018 Nov;142(5):1537-1547.e8. doi: 10.1016/j.jaci.2017.12.984. Epub 2018 Jan 31.

35.

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.

Emgård J, Kammoun H, García-Cassani B, Chesné J, Parigi SM, Jacob JM, Cheng HW, Evren E, Das S, Czarnewski P, Sleiers N, Melo-Gonzalez F, Kvedaraite E, Svensson M, Scandella E, Hepworth MR, Huber S, Ludewig B, Peduto L, Villablanca EJ, Veiga-Fernandes H, Pereira JP, Flavell RA, Willinger T.

Immunity. 2018 Jan 16;48(1):120-132.e8. doi: 10.1016/j.immuni.2017.11.020.

36.

m6A mRNA methylation sustains Treg suppressive functions.

Tong J, Cao G, Zhang T, Sefik E, Amezcua Vesely MC, Broughton JP, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB.

Cell Res. 2018 Feb;28(2):253-256. doi: 10.1038/cr.2018.7. Epub 2018 Jan 5. No abstract available.

37.

IRF8-dependent molecular complexes control the Th9 transcriptional program.

Humblin E, Thibaudin M, Chalmin F, Derangère V, Limagne E, Richard C, Flavell RA, Chevrier S, Ladoire S, Berger H, Boidot R, Apetoh L, Végran F, Ghiringhelli F.

Nat Commun. 2017 Dec 12;8(1):2085. doi: 10.1038/s41467-017-01070-w.

38.

Corrigendum: Development and function of human innate immune cells in a humanized mouse model.

Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka AK, Manz MG, Flavell RA.

Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211c. No abstract available.

PMID:
29220023
39.

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

Ring NG, Herndler-Brandstetter D, Weiskopf K, Shan L, Volkmer JP, George BM, Lietzenmayer M, McKenna KM, Naik TJ, McCarty A, Zheng Y, Ring AM, Flavell RA, Weissman IL.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585. doi: 10.1073/pnas.1710877114. Epub 2017 Nov 20.

40.

Harnessing the power of regulatory T-cells to control autoimmune diabetes: overview and perspective.

Yu H, Paiva R, Flavell RA.

Immunology. 2018 Feb;153(2):161-170. doi: 10.1111/imm.12867. Epub 2017 Dec 11. Review.

41.

A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.

Kleinschmidt D, Giannou AD, McGee HM, Kempski J, Steglich B, Huber FJ, Ernst TM, Shiri AM, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse AW, Axelrod JH, Galun E, Flavell RA, Gagliani N, Huber S.

J Immunol. 2017 Dec 15;199(12):4078-4090. doi: 10.4049/jimmunol.1700587. Epub 2017 Nov 6.

42.

Humanized mouse model supports development, function, and tissue residency of human natural killer cells.

Herndler-Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, Strowig T, de Zoete MR, Palm NW, Chen J, Blish CA, Frleta D, Gurer C, Macdonald LE, Murphy AJ, Yancopoulos GD, Montgomery RR, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9626-E9634. doi: 10.1073/pnas.1705301114. Epub 2017 Oct 25.

43.

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells.

Roy U, Gálvez EJC, Iljazovic A, Lesker TR, Błażejewski AJ, Pils MC, Heise U, Huber S, Flavell RA, Strowig T.

Cell Rep. 2017 Oct 24;21(4):994-1008. doi: 10.1016/j.celrep.2017.09.097.

44.

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection.

Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, Ke R, Flavell RA, Siliciano JD, Siliciano RF.

Immunity. 2017 Oct 17;47(4):766-775.e3. doi: 10.1016/j.immuni.2017.09.014.

45.

A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.

Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ.

Cell Rep. 2017 Sep 19;20(12):2775-2783. doi: 10.1016/j.celrep.2017.08.025.

46.

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J.

Immunity. 2017 Sep 19;47(3):435-449.e8. doi: 10.1016/j.immuni.2017.08.012.

47.

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.

Rivera Vargas T, Cai Z, Shen Y, Dosset M, Benoit-Lizon I, Martin T, Roussey A, Flavell RA, Ghiringhelli F, Apetoh L.

Nat Commun. 2017 Sep 15;8(1):559. doi: 10.1038/s41467-017-00468-w.

48.

No Oxygen? No Glucose? No Problem: Fatty Acid Catabolism Enhances Effector CD8+ TILs.

Bailis W, Shyer JA, Chiorazzi M, Flavell RA.

Cancer Cell. 2017 Sep 11;32(3):280-281. doi: 10.1016/j.ccell.2017.08.013.

49.

Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development.

Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, Herold KC, Wen L, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10443-10448. doi: 10.1073/pnas.1705599114. Epub 2017 Sep 11.

50.

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.

Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, Ma H, Liao Y, Wen X, Roden C, Tobiasova Z, Wei Z, Zhao J, Liu J, Zheng J, Guo B, Khan SA, Bosenberg M, Flavell RA, Lu J.

Immunity. 2017 Aug 15;47(2):284-297.e5. doi: 10.1016/j.immuni.2017.07.020.

Supplemental Content

Loading ...
Support Center