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Items: 1 to 50 of 1320

1.

Homeobox protein Hhex negatively regulates Treg cells by inhibiting Foxp3 expression and function.

Jang SW, Hwang SS, Kim HS, Kim MK, Lee WH, Hwang SU, Gwak J, Yew SK, Flavell RA, Lee GR.

Proc Natl Acad Sci U S A. 2019 Dec 2. pii: 201907224. doi: 10.1073/pnas.1907224116. [Epub ahead of print]

PMID:
31792183
2.

IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus.

Geginat J, Vasco M, Gerosa M, Tas SW, Pagani M, Grassi F, Flavell RA, Meroni P, Abrignani S.

Semin Immunol. 2019 Aug;44:101330. doi: 10.1016/j.smim.2019.101330. Epub 2019 Nov 15. Review.

PMID:
31735515
3.

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.

Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL.

Nat Commun. 2019 Nov 13;10(1):5137. doi: 10.1038/s41467-019-12970-4.

4.

Author Correction: Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.

Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Cruz CSD, Palm NW, Jackson R, Flavell RA.

Nature. 2019 Nov;575(7784):E7. doi: 10.1038/s41586-019-1755-5.

PMID:
31712625
5.

High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection.

Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM.

ACS Infect Dis. 2019 Nov 21. doi: 10.1021/acsinfecdis.9b00196. [Epub ahead of print]

PMID:
31697062
6.

Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer.

Korenchan DE, Bok R, Sriram R, Liu K, Santos RD, Qin H, Lobach I, Korn N, Wilson DM, Kurhanewicz J, Flavell RR.

Oncotarget. 2019 Oct 22;10(58):6096-6110. doi: 10.18632/oncotarget.27225. eCollection 2019 Oct 22.

7.

hnRNPA2B1: a nuclear DNA sensor in antiviral immunity.

Zhang X, Flavell RA, Li HB.

Cell Res. 2019 Nov;29(11):879-880. doi: 10.1038/s41422-019-0226-8. No abstract available.

PMID:
31471560
8.

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Sep;573(7773):E2. doi: 10.1038/s41586-019-1490-y.

PMID:
31447485
9.

Publisher Correction: HER2 joins AKT to inhibit STING immunity.

Odell ID, Flavell RA.

Nat Cell Biol. 2019 Oct;21(10):1301. doi: 10.1038/s41556-019-0395-1.

PMID:
31444402
10.

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection.

Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, Xu H, Iijima N, Pillai PS, Kaplan DH, Weaver CT, Kluger Y, Kowalczyk MS, Iwasaki A, Pereira JP, Esplugues E, Gagliani N, Flavell RA.

Cell. 2019 Aug 22;178(5):1176-1188.e15. doi: 10.1016/j.cell.2019.07.032.

PMID:
31442406
11.

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.

Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Dela Cruz CS, Palm NW, Jackson R, Flavell RA.

Nature. 2019 Sep;573(7772):69-74. doi: 10.1038/s41586-019-1485-8. Epub 2019 Aug 21. Erratum in: Nature. 2019 Nov 12;:.

PMID:
31435009
12.

Publisher Correction: Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella M, Gamini R, Sécca C, Collins PL, Zhao S, Peng V, Robinette ML, Schettini J, Zaitsev K, Gordon W, Bando JK, Yomogida K, Cortez V, Fronick C, Fulton R, Lin LL, Gilfillan S, Flavell RA, Shan L, Artyomov MN, Bowman M, Oltz EM, Jelinsky SA, Colonna M.

Nat Immunol. 2019 Oct;20(10):1405. doi: 10.1038/s41590-019-0474-2.

PMID:
31388149
13.

Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy.

Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR.

Mol Pharm. 2019 Sep 3;16(9):3831-3841. doi: 10.1021/acs.molpharmaceut.9b00464. Epub 2019 Aug 16.

PMID:
31381351
14.

HER2 joins AKT to inhibit STING immunity.

Odell ID, Flavell RA.

Nat Cell Biol. 2019 Aug;21(8):917-918. doi: 10.1038/s41556-019-0368-4. Review. No abstract available. Erratum in: Nat Cell Biol. 2019 Oct;21(10):1301.

PMID:
31371829
15.

Amino Acid-Derived Sensors for Specific Zn2+ Detection Using Hyperpolarized 13 C Magnetic Resonance Spectroscopy.

Wang S, Korenchan DE, Perez PM, Taglang C, Hayes TR, Sriram R, Bok R, Hong AS, Wu Y, Li H, Wang Z, Kurhanewicz J, Wilson DM, Flavell RR.

Chemistry. 2019 Sep 12;25(51):11842-11846. doi: 10.1002/chem.201902771. Epub 2019 Aug 20.

PMID:
31338914
16.

Spatiotemporal pH Heterogeneity as a Promoter of Cancer Progression and Therapeutic Resistance.

Korenchan DE, Flavell RR.

Cancers (Basel). 2019 Jul 20;11(7). pii: E1026. doi: 10.3390/cancers11071026. Review.

17.

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Jul;571(7765):403-407. doi: 10.1038/s41586-019-1311-3. Epub 2019 Jun 19. Erratum in: Nature. 2019 Sep;573(7773):E2.

PMID:
31217581
18.

Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella M, Gamini R, Sécca C, Collins PL, Zhao S, Peng V, Robinette ML, Schettini J, Zaitsev K, Gordon W, Bando JK, Yomogida K, Cortez V, Fronick C, Fulton R, Lin LL, Gilfillan S, Flavell RA, Shan L, Artyomov MN, Bowman M, Oltz EM, Jelinsky SA, Colonna M.

Nat Immunol. 2019 Aug;20(8):980-991. doi: 10.1038/s41590-019-0425-y. Epub 2019 Jun 17. Erratum in: Nat Immunol. 2019 Aug 6;:.

PMID:
31209406
19.

Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis.

Tang P, Low HB, Png CW, Torta F, Kumar JK, Lim HY, Zhou Y, Yang H, Angeli V, Shabbir A, Tai ES, Flavell RA, Dong C, Wenk MR, Yang DY, Zhang Y.

Hepatol Commun. 2019 Mar 1;3(6):748-762. doi: 10.1002/hep4.1324. eCollection 2019 Jun.

20.

Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.

Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR.

Magn Reson Med. 2019 Sep;82(3):959-972. doi: 10.1002/mrm.27780. Epub 2019 May 3.

PMID:
31050049
21.

Single-Center Prospective Evaluation of 68Ga-PSMA-11 PET in Biochemical Recurrence of Prostate Cancer.

Lawhn-Heath C, Flavell RR, Behr SC, Yohannan T, Greene KL, Feng F, Carroll PR, Hope TA.

AJR Am J Roentgenol. 2019 Aug;213(2):266-274. doi: 10.2214/AJR.18.20699. Epub 2019 Apr 30.

PMID:
31039025
22.

Quantitative and Qualitative Improvement of Low-Count [68Ga]Citrate and [90Y]Microspheres PET Image Reconstructions Using Block Sequential Regularized Expectation Maximization Algorithm.

Seo Y, Khalighi MM, Wangerin KA, Deller TW, Wang YH, Jivan S, Kohi MP, Aggarwal R, Flavell RR, Behr SC, Evans MJ.

Mol Imaging Biol. 2019 Apr 15. doi: 10.1007/s11307-019-01347-0. [Epub ahead of print]

PMID:
30993558
23.

miR-181a/b downregulation exerts a protective action on mitochondrial disease models.

Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez-Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao-Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B.

EMBO Mol Med. 2019 May;11(5). pii: e8734. doi: 10.15252/emmm.201708734.

24.

Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial.

Fendler WP, Calais J, Eiber M, Flavell RR, Mishoe A, Feng FY, Nguyen HG, Reiter RE, Rettig MB, Okamoto S, Emmett L, Zacho HD, Ilhan H, Wetter A, Rischpler C, Schoder H, Burger IA, Gartmann J, Smith R, Small EJ, Slavik R, Carroll PR, Herrmann K, Czernin J, Hope TA.

JAMA Oncol. 2019 Jun 1;5(6):856-863. doi: 10.1001/jamaoncol.2019.0096.

25.

Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis.

Barger SR, Reilly NS, Shutova MS, Li Q, Maiuri P, Heddleston JM, Mooseker MS, Flavell RA, Svitkina T, Oakes PW, Krendel M, Gauthier NC.

Nat Commun. 2019 Mar 19;10(1):1249. doi: 10.1038/s41467-019-09104-1.

26.

Breeding progress and preparedness for mass-scale deployment of perennial lignocellulosic biomass crops switchgrass, miscanthus, willow and poplar.

Clifton-Brown J, Harfouche A, Casler MD, Dylan Jones H, Macalpine WJ, Murphy-Bokern D, Smart LB, Adler A, Ashman C, Awty-Carroll D, Bastien C, Bopper S, Botnari V, Brancourt-Hulmel M, Chen Z, Clark LV, Cosentino S, Dalton S, Davey C, Dolstra O, Donnison I, Flavell R, Greef J, Hanley S, Hastings A, Hertzberg M, Hsu TW, Huang LS, Iurato A, Jensen E, Jin X, Jørgensen U, Kiesel A, Kim DS, Liu J, McCalmont JP, McMahon BG, Mos M, Robson P, Sacks EJ, Sandu A, Scalici G, Schwarz K, Scordia D, Shafiei R, Shield I, Slavov G, Stanton BJ, Swaminathan K, Taylor G, Torres AF, Trindade LM, Tschaplinski T, Tuskan GA, Yamada T, Yeon Yu C, Zalesny RS Jr, Zong J, Lewandowski I.

Glob Change Biol Bioenergy. 2019 Jan;11(1):118-151. doi: 10.1111/gcbb.12566. Epub 2018 Oct 23.

27.

Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT.

Raghavan K, Wen KW, Small EJ, Ha P, Flavell RR.

Clin Nucl Med. 2019 May;44(5):e367-e369. doi: 10.1097/RLU.0000000000002507.

PMID:
30829856
28.

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.

Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS.

Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186.

29.

The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI.

Bok R, Lee J, Sriram R, Keshari K, Sukumar S, Daneshmandi S, Korenchan DE, Flavell RR, Vigneron DB, Kurhanewicz J, Seth P.

Cancers (Basel). 2019 Feb 22;11(2). pii: E257. doi: 10.3390/cancers11020257.

30.

Role of IL-10 Receptor Signaling in the Function of CD4+ T-Regulatory Type 1 cells: T-Cell Therapy in Patients with Inflammatory Bowel Disease.

Soukou S, Brockmann L, Bedke T, Gagliani N, Flavell RA, Huber S.

Crit Rev Immunol. 2018;38(5):415-431. doi: 10.1615/CritRevImmunol.2018026850. Review.

PMID:
30806217
31.

Immunity, microbiota and kidney disease.

Knauf F, Brewer JR, Flavell RA.

Nat Rev Nephrol. 2019 May;15(5):263-274. doi: 10.1038/s41581-019-0118-7. Review.

PMID:
30796361
32.

Antiviral immunity: a link to bile acids.

Wang J, Flavell RA, Li HB.

Cell Res. 2019 Mar;29(3):177-178. doi: 10.1038/s41422-019-0148-5. No abstract available.

PMID:
30778178
33.

A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.

Song Y, Rongvaux A, Taylor A, Jiang T, Tebaldi T, Balasubramanian K, Bagale A, Terzi YK, Gbyli R, Wang X, Fu X, Gao Y, Zhao J, Podoltsev N, Xu M, Neparidze N, Wong E, Torres R, Bruscia EM, Kluger Y, Manz MG, Flavell RA, Halene S.

Nat Commun. 2019 Jan 21;10(1):366. doi: 10.1038/s41467-018-08166-x.

34.

Heterogeneous Uptake of 18F-FDG and 68Ga-PSMA-11 in Hepatocellular Carcinoma.

Perez PM, Flavell RR, Kelley RK, Umetsu S, Behr SC.

Clin Nucl Med. 2019 Mar;44(3):e133-e135. doi: 10.1097/RLU.0000000000002452.

PMID:
30624275
35.

Collecting wild Miscanthus germplasm in Asia for crop improvement and conservation in Europe whilst adhering to the guidelines of the United Nations' Convention on Biological Diversity.

Huang LS, Flavell R, Donnison IS, Chiang YC, Hastings A, Hayes C, Heidt C, Hong H, Hsu TW, Humphreys M, Jackson J, Norris J, Schwarz KU, Squance M, Swaller T, Thomas ID, Van Assche W, Xi Q, Yamada T, Youell S, Clifton-Brown J.

Ann Bot. 2019 Oct 29;124(4):591-604. doi: 10.1093/aob/mcy231.

36.

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells.

Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi SM, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki JR, Lohse AW, Flavell RA, Krebs C, Gustafsson JA, Antonson P, Roncarolo MG, Villablanca EJ, Gagliani N, Huber S.

Nat Commun. 2018 Dec 21;9(1):5457. doi: 10.1038/s41467-018-07581-4.

37.

The translation of non-canonical open reading frames controls mucosal immunity.

Jackson R, Kroehling L, Khitun A, Bailis W, Jarret A, York AG, Khan OM, Brewer JR, Skadow MH, Duizer C, Harman CCD, Chang L, Bielecki P, Solis AG, Steach HR, Slavoff S, Flavell RA.

Nature. 2018 Dec;564(7736):434-438. doi: 10.1038/s41586-018-0794-7. Epub 2018 Dec 12.

PMID:
30542152
38.

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.

Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M.

Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8.

39.

Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer.

Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y.

J Nucl Med. 2019 Jul;60(7):910-916. doi: 10.2967/jnumed.118.220715. Epub 2018 Nov 21.

PMID:
30464040
40.

Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells.

Ding S, Zhu S, Ren L, Feng N, Song Y, Ge X, Li B, Flavell RA, Greenberg HB.

Elife. 2018 Nov 21;7. pii: e39494. doi: 10.7554/eLife.39494.

41.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells.

Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber FJ, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell RA, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S.

J Immunol. 2018 Dec 15;201(12):3558-3568. doi: 10.4049/jimmunol.1800711. Epub 2018 Nov 16.

PMID:
30446566
42.

A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain.

Ding Y, Sohn JH, Kawczynski MG, Trivedi H, Harnish R, Jenkins NW, Lituiev D, Copeland TP, Aboian MS, Mari Aparici C, Behr SC, Flavell RR, Huang SY, Zalocusky KA, Nardo L, Seo Y, Hawkins RA, Hernandez Pampaloni M, Hadley D, Franc BL.

Radiology. 2019 Feb;290(2):456-464. doi: 10.1148/radiol.2018180958. Epub 2018 Nov 6.

PMID:
30398430
43.

Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases.

Perez PM, Hope TA, Behr SC, van Zante A, Small EJ, Flavell RR.

Clin Nucl Med. 2019 Jan;44(1):e28-e32. doi: 10.1097/RLU.0000000000002367.

PMID:
30394930
44.

Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity.

Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, Moran T, Flavell R, Aaronson S, Hu HM, Arase H, Ramanathan S, Flores R, Pan PY, Chen SH.

J Clin Invest. 2018 Dec 3;128(12):5647-5662. doi: 10.1172/JCI97570. Epub 2018 Oct 22.

45.

cGAS activation in phased droplets.

Liu Y, Li HB, Flavell RA.

Cell Res. 2018 Oct;28(10):967-968. doi: 10.1038/s41422-018-0087-6. No abstract available.

46.

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.

Tye H, Yu CH, Simms LA, de Zoete MR, Kim ML, Zakrzewski M, Penington JS, Harapas CR, Souza-Fonseca-Guimaraes F, Wockner LF, Preaudet A, Mielke LA, Wilcox SA, Ogura Y, Corr SC, Kanojia K, Kouremenos KA, De Souza DP, McConville MJ, Flavell RA, Gerlic M, Kile BT, Papenfuss AT, Putoczki TL, Radford-Smith GL, Masters SL.

Nat Commun. 2018 Sep 13;9(1):3728. doi: 10.1038/s41467-018-06125-0.

47.

Lack of Sprouty 1 and 2 enhances survival of effector CD8+ T cells and yields more protective memory cells.

Shehata HM, Khan S, Chen E, Fields PE, Flavell RA, Sanjabi S.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8939-E8947. doi: 10.1073/pnas.1808320115. Epub 2018 Aug 20.

48.

RNA m6A modification and its function in diseases.

Tong J, Flavell RA, Li HB.

Front Med. 2018 Aug;12(4):481-489. doi: 10.1007/s11684-018-0654-8. Epub 2018 Aug 10. Review.

PMID:
30097961
49.

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

Stefanski HE, Xing Y, Taylor PA, Maio S, Henao-Meija J, Williams A, Flavell RA, Hollander GA, Blazar BR.

PLoS One. 2018 Jun 27;13(6):e0198871. doi: 10.1371/journal.pone.0198871. eCollection 2018.

50.

Detection of Metastatic Meningioma to the Liver Using 68Ga-DOTA-Octreotate PET/CT.

Villanueva-Meyer JE, Magill ST, Lee JC, Umetsu SE, Flavell RR.

Clin Nucl Med. 2018 Sep;43(9):e338-e340. doi: 10.1097/RLU.0000000000002183.

PMID:
29939957

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