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Items: 1 to 50 of 1270

1.

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

Stefanski HE, Xing Y, Taylor PA, Maio S, Henao-Meija J, Williams A, Flavell RA, Hollander GA, Blazar BR.

PLoS One. 2018 Jun 27;13(6):e0198871. doi: 10.1371/journal.pone.0198871. eCollection 2018.

2.

Detection of Metastatic Meningioma to the Liver Using 68Ga-DOTA-Octreotate PET/CT.

Villanueva-Meyer JE, Magill ST, Lee JC, Umetsu SE, Flavell RR.

Clin Nucl Med. 2018 Jun 22. doi: 10.1097/RLU.0000000000002183. [Epub ahead of print]

PMID:
29939957
3.

IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN.

Diefenhardt P, Nosko A, Kluger MA, Richter JV, Wegscheid C, Kobayashi Y, Tiegs G, Huber S, Flavell RA, Stahl RAK, Steinmetz OM.

J Am Soc Nephrol. 2018 Jul;29(7):1825-1837. doi: 10.1681/ASN.2017091044. Epub 2018 Jun 4.

PMID:
29866800
4.

Family-based study reveals decreased abundance of sputum Granulicatella in asthmatics.

Wang L, de Ángel Solá D, Mao Y, Bielecki P, Zhu Y, Sun Z, Shan L, Flavell RA, Bazzy-Asaad A, DeWan A.

Allergy. 2018 Jun 4. doi: 10.1111/all.13493. [Epub ahead of print] No abstract available.

PMID:
29862523
5.

Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes.

Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM.

Sci Rep. 2018 May 21;8(1):7928. doi: 10.1038/s41598-018-26296-6.

6.

Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI.

Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR.

Chem Commun (Camb). 2018 May 17;54(41):5233-5236. doi: 10.1039/c8cc02246a.

PMID:
29726563
7.

[11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism.

Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM.

ACS Infect Dis. 2018 Jul 13;4(7):1067-1072. doi: 10.1021/acsinfecdis.8b00061. Epub 2018 May 8.

PMID:
29712422
8.

Antigen-mediated regulation in monoclonal gammopathies and myeloma.

Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV.

JCI Insight. 2018 Apr 19;3(8). pii: 98259. doi: 10.1172/jci.insight.98259. [Epub ahead of print]

9.

NLRP6 and Dysbiosis: Avoiding the Luring Attraction of Over-Simplification.

Elinav E, Henao-Mejia J, Strowig T, Flavell R.

Immunity. 2018 Apr 17;48(4):603-604. doi: 10.1016/j.immuni.2018.04.002. No abstract available.

PMID:
29669238
10.

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

Herndler-Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, Lietzenmayer M, Kroehling L, Takumi A, Kometani K, Inoue T, Kluger Y, Kaech SM, Kurosaki T, Okada T, Flavell RA.

Immunity. 2018 Apr 17;48(4):716-729.e8. doi: 10.1016/j.immuni.2018.03.015. Epub 2018 Apr 3.

PMID:
29625895
11.

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM.

J Exp Med. 2018 Apr 2;215(4):1153-1168. doi: 10.1084/jem.20171352. Epub 2018 Feb 15.

PMID:
29449309
12.

Circuit Design Features of a Stable Two-Cell System.

Zhou X, Franklin RA, Adler M, Jacox JB, Bailis W, Shyer JA, Flavell RA, Mayo A, Alon U, Medzhitov R.

Cell. 2018 Feb 8;172(4):744-757.e17. doi: 10.1016/j.cell.2018.01.015. Epub 2018 Feb 1.

PMID:
29398113
13.

Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.

Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J.

J Allergy Clin Immunol. 2018 Jan 31. pii: S0091-6749(18)30078-2. doi: 10.1016/j.jaci.2017.12.984. [Epub ahead of print]

14.

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.

Emgård J, Kammoun H, García-Cassani B, Chesné J, Parigi SM, Jacob JM, Cheng HW, Evren E, Das S, Czarnewski P, Sleiers N, Melo-Gonzalez F, Kvedaraite E, Svensson M, Scandella E, Hepworth MR, Huber S, Ludewig B, Peduto L, Villablanca EJ, Veiga-Fernandes H, Pereira JP, Flavell RA, Willinger T.

Immunity. 2018 Jan 16;48(1):120-132.e8. doi: 10.1016/j.immuni.2017.11.020.

15.

Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate.

von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ.

Magn Reson Med. 2018 Apr;79(4):1862-1869. doi: 10.1002/mrm.27054. Epub 2018 Jan 3.

PMID:
29314217
16.

m6A mRNA methylation sustains Treg suppressive functions.

Tong J, Cao G, Zhang T, Sefik E, Amezcua Vesely MC, Broughton JP, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB.

Cell Res. 2018 Feb;28(2):253-256. doi: 10.1038/cr.2018.7. Epub 2018 Jan 5. No abstract available.

PMID:
29303144
17.

Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9".

Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Høyer-Hansen M, Elling F, Wallach D, Flavell R, Kroemer G, Nylandsted J, Jäättelä M.

Mol Cell Biol. 2017 Dec 29;38(2). pii: e00563-17. doi: 10.1128/MCB.00563-17. Print 2018 Jan 15. No abstract available.

18.

Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure.

Gálvez EJC, Iljazovic A, Gronow A, Flavell R, Strowig T.

Cell Rep. 2017 Dec 26;21(13):3914-3926. doi: 10.1016/j.celrep.2017.12.027.

19.

Discordant Findings on 18F-NaF and 99mTc-HDP Bone Scans in a Patient With ATTR Cardiac Amyloidosis.

Ng QKT, Sethi P, Saunders TA, Pampaloni MH, Flavell RR.

Clin Nucl Med. 2018 Mar;43(3):e89-e92. doi: 10.1097/RLU.0000000000001933.

PMID:
29261619
20.

IRF8-dependent molecular complexes control the Th9 transcriptional program.

Humblin E, Thibaudin M, Chalmin F, Derangère V, Limagne E, Richard C, Flavell RA, Chevrier S, Ladoire S, Berger H, Boidot R, Apetoh L, Végran F, Ghiringhelli F.

Nat Commun. 2017 Dec 12;8(1):2085. doi: 10.1038/s41467-017-01070-w.

21.

Corrigendum: Development and function of human innate immune cells in a humanized mouse model.

Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka AK, Manz MG, Flavell RA.

Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211c. No abstract available.

PMID:
29220023
22.

Cardiac Fibroma: An Uncommon Cause of a Fixed Defect on Myocardial Perfusion Imaging.

Pittman S, Sethi P, Flavell RR, Pampaloni MH.

Clin Nucl Med. 2018 Feb;43(2):e56-e58. doi: 10.1097/RLU.0000000000001924.

PMID:
29215416
23.

Effect of Time-of-Flight and Regularized Reconstructions on Quantitative Measurements and Qualitative Assessments in Newly Diagnosed Prostate Cancer With 18F-Fluorocholine Dual Time Point PET/MRI.

Behr SC, Mollard BJ, Yang J, Flavell RR, Hawkins RA, Seo Y.

Mol Imaging. 2017 Jan-Dec;16:1536012117736703. doi: 10.1177/1536012117736703.

24.

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

Ring NG, Herndler-Brandstetter D, Weiskopf K, Shan L, Volkmer JP, George BM, Lietzenmayer M, McKenna KM, Naik TJ, McCarty A, Zheng Y, Ring AM, Flavell RA, Weissman IL.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585. doi: 10.1073/pnas.1710877114. Epub 2017 Nov 20.

25.

Harnessing the power of regulatory T-cells to control autoimmune diabetes: overview and perspective.

Yu H, Paiva R, Flavell RA.

Immunology. 2018 Feb;153(2):161-170. doi: 10.1111/imm.12867. Epub 2017 Dec 11. Review.

PMID:
29155454
26.

A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.

Kleinschmidt D, Giannou AD, McGee HM, Kempski J, Steglich B, Huber FJ, Ernst TM, Shiri AM, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse AW, Axelrod JH, Galun E, Flavell RA, Gagliani N, Huber S.

J Immunol. 2017 Dec 15;199(12):4078-4090. doi: 10.4049/jimmunol.1700587. Epub 2017 Nov 6.

PMID:
29109123
27.

Abnormal pulmonary 18F-florbetapir uptake in a patient evaluated for recurrent cardiac amyloidosis following orthotopic heart transplant.

Pittman S, Sethi P, Flavell RR, De Marco T, Hernandez Pampaloni M.

J Nucl Cardiol. 2017 Nov 3. doi: 10.1007/s12350-017-1096-4. [Epub ahead of print] No abstract available.

PMID:
29101671
28.

Humanized mouse model supports development, function, and tissue residency of human natural killer cells.

Herndler-Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, Strowig T, de Zoete MR, Palm NW, Chen J, Blish CA, Frleta D, Gurer C, Macdonald LE, Murphy AJ, Yancopoulos GD, Montgomery RR, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9626-E9634. doi: 10.1073/pnas.1705301114. Epub 2017 Oct 25.

29.

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells.

Roy U, Gálvez EJC, Iljazovic A, Lesker TR, Błażejewski AJ, Pils MC, Heise U, Huber S, Flavell RA, Strowig T.

Cell Rep. 2017 Oct 24;21(4):994-1008. doi: 10.1016/j.celrep.2017.09.097.

30.

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection.

Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, Ke R, Flavell RA, Siliciano JD, Siliciano RF.

Immunity. 2017 Oct 17;47(4):766-775.e3. doi: 10.1016/j.immuni.2017.09.014.

31.

A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.

Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ.

Cell Rep. 2017 Sep 19;20(12):2775-2783. doi: 10.1016/j.celrep.2017.08.025.

32.

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J.

Immunity. 2017 Sep 19;47(3):435-449.e8. doi: 10.1016/j.immuni.2017.08.012.

PMID:
28930659
33.

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.

Rivera Vargas T, Cai Z, Shen Y, Dosset M, Benoit-Lizon I, Martin T, Roussey A, Flavell RA, Ghiringhelli F, Apetoh L.

Nat Commun. 2017 Sep 15;8(1):559. doi: 10.1038/s41467-017-00468-w.

34.

No Oxygen? No Glucose? No Problem: Fatty Acid Catabolism Enhances Effector CD8+ TILs.

Bailis W, Shyer JA, Chiorazzi M, Flavell RA.

Cancer Cell. 2017 Sep 11;32(3):280-281. doi: 10.1016/j.ccell.2017.08.013.

PMID:
28898693
35.

Reply: Greener revolutions for all require transparency and diversity, not secrecy.

Flavell RB.

Nat Biotechnol. 2017 Sep 11;35(9):818-819. doi: 10.1038/nbt.3952. No abstract available.

PMID:
28898206
36.

Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development.

Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, Herold KC, Wen L, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10443-10448. doi: 10.1073/pnas.1705599114. Epub 2017 Sep 11.

37.

Exploring Metabolism In Vivo Using Endogenous 11C Metabolic Tracers.

Neumann K, Flavell R, Wilson DM.

Semin Nucl Med. 2017 Sep;47(5):461-473. doi: 10.1053/j.semnuclmed.2017.05.003. Epub 2017 Jul 11. Review.

38.

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.

Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, Ma H, Liao Y, Wen X, Roden C, Tobiasova Z, Wei Z, Zhao J, Liu J, Zheng J, Guo B, Khan SA, Bosenberg M, Flavell RA, Lu J.

Immunity. 2017 Aug 15;47(2):284-297.e5. doi: 10.1016/j.immuni.2017.07.020.

PMID:
28813659
39.

Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers.

Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM.

Sci Rep. 2017 Aug 11;7(1):7903. doi: 10.1038/s41598-017-08415-x.

40.

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.

Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA.

Nature. 2017 Aug 17;548(7667):338-342. doi: 10.1038/nature23450. Epub 2017 Aug 9.

41.

PTPN22 inhibition resets defective human central B cell tolerance.

Schickel JN, Kuhny M, Baldo A, Bannock JM, Massad C, Wang H, Katz N, Oe T, Menard L, Soulas-Sprauel P, Strowig T, Flavell R, Meffre E.

Sci Immunol. 2016 Jul 22;1(1):aaf7153. doi: 10.1126/sciimmunol.aaf7153. Epub 2016 Jul 22.

PMID:
28783674
42.

AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome.

Cunha LD, Silva ALN, Ribeiro JM, Mascarenhas DPA, Quirino GFS, Santos LL, Flavell RA, Zamboni DS.

Cell Rep. 2017 Jul 25;20(4):794-805. doi: 10.1016/j.celrep.2017.06.086.

43.

Long-term consumption of caffeine-free high sucrose cola beverages aggravates the pathogenesis of EAE in mice.

Cao G, Wang Q, Huang W, Tong J, Ye D, He Y, Liu Z, Tang X, Cheng H, Wen Q, Li D, Chau HT, Wen Y, Zhong H, Meng Z, Liu H, Wu Z, Zhao L, Flavell RA, Zhou H, Xu A, Yang H, Yin Z.

Cell Discov. 2017 Jun 20;3:17020. doi: 10.1038/celldisc.2017.20. eCollection 2017.

44.

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA.

Nature. 2017 Jun 29;546(7660):667-670. doi: 10.1038/nature22967. Epub 2017 Jun 21.

45.

Enhancement of IFNγ Production by Distinct Commensals Ameliorates Salmonella-Induced Disease.

Thiemann S, Smit N, Roy U, Lesker TR, Gálvez EJC, Helmecke J, Basic M, Bleich A, Goodman AL, Kalinke U, Flavell RA, Erhardt M, Strowig T.

Cell Host Microbe. 2017 Jun 14;21(6):682-694.e5. doi: 10.1016/j.chom.2017.05.005.

46.

Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation.

Błażejewski AJ, Thiemann S, Schenk A, Pils MC, Gálvez EJC, Roy U, Heise U, de Zoete MR, Flavell RA, Strowig T.

Cell Rep. 2017 Jun 13;19(11):2319-2330. doi: 10.1016/j.celrep.2017.05.058.

47.

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation.

Patel AA, Zhang Y, Fullerton JN, Boelen L, Rongvaux A, Maini AA, Bigley V, Flavell RA, Gilroy DW, Asquith B, Macallan D, Yona S.

J Exp Med. 2017 Jul 3;214(7):1913-1923. doi: 10.1084/jem.20170355. Epub 2017 Jun 12.

48.

Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells.

Bosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, Weinstein JS, Licona-Limon P, Schmid ET, Pelorosso F, Gagliani N, Craft JE, Flavell RA, Ghosh S, Rothlin CV.

Science. 2017 Jun 9;356(6342):1072-1076. doi: 10.1126/science.aai8132. Epub 2017 May 11.

49.

miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling.

Hori D, Dunkerly-Eyring B, Nomura Y, Biswas D, Steppan J, Henao-Mejia J, Adachi H, Santhanam L, Berkowitz DE, Steenbergen C, Flavell RA, Das S.

PLoS One. 2017 Mar 21;12(3):e0174108. doi: 10.1371/journal.pone.0174108. eCollection 2017.

50.

Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.

Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR.

Analyst. 2017 May 2;142(9):1429-1433. doi: 10.1039/c7an00076f.

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